Research Topics
| E O KajanderSummaryAffiliation: University of Kuopio Country: Finland Publications
| Collaborators
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Detail Information
Publications
Nanobacteria: an alternative mechanism for pathogenic intra- and extracellular calcification and stone formationE O Kajander
Department of Biochemistry and Biotechnology, University of Kuopio, P O B 1627, FIN 70211, Kuopio, Finland
Proc Natl Acad Sci U S A 95:8274-9. 1998..4, at physiological phosphate and calcium concentrations. Nanobacteria can produce apatite in media mimicking tissue fluids and glomerular filtrate and provide a unique model for in vitro studies on calcification...
Nanobacteria: controversial pathogens in nephrolithiasis and polycystic kidney diseaseE O Kajander
Department of Biochemistry, University of Kuopio, Kuopio, Finland
Curr Opin Nephrol Hypertens 10:445-52. 2001..Kidney cyst formation is hypothesized to involve nanobacteria-induced tubular damage and defective tissue regeneration yielding cyst formation, the extent of which is dependent on genetic vulnerability...
Characteristics of nanobacteria and their possible role in stone formationE Olavi Kajander
Department of Biochemistry, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
Urol Res 31:47-54. 2003..Our hypothesis underlines the role of active nidi: even supersaturated urine requires nidi for crystallization to appear...
Nanobacteria--propagating calcifying nanoparticlesE O Kajander
Department of Biochemistry, University of Kuopio, Kuopio, Finland
Lett Appl Microbiol 42:549-52. 2006..Despite the controversy of their classification, they propagate and cause cell death in vitro and are associated or found in many human diseases. Thus, more efforts should be focussed on research on pathogenicity of CNP...
Inhibition of nanobacteria by antimicrobial drugs as measured by a modified microdilution methodN Ciftcioglu
Department of Biochemistry, University of Kuopio, FIN 70211, Kuopio, Finland
Antimicrob Agents Chemother 46:2077-86. 2002..Insights into the nature of NB, the action(s) of these drugs, and the role of NB in calcifying diseases may be gained by exploiting this in vitro inhibition test system...
Nanobacteria: an infectious cause for kidney stone formationN Ciftcioglu
Department of Biochemistry, University of Kuopio, Finland
Kidney Int 56:1893-8. 1999..Nanobacteria produce carbonate apatite on their cell walls. Data on Randall's plaques suggest that apatite may initiate kidney stone formation. We assessed nanobacteria in 72 consecutively collected kidney stones from Finnish patients...
[Culture and identification of nanobacteria in bile]Yongguo Li
Second Xiangya Hospital, Central-South University, Changsha 410011, China
Zhonghua Yi Xue Za Zhi 82:1557-60. 2002..Calcific staining is of great value to identification of nanobacteria. Precipitation of white floccules adhering to the tube is an important microbiological characteristic of nanobacteria...
