Valtteri Kaasinen

Summary

Affiliation: University of Turku
Country: Finland

Publications

  1. doi request reprint Effects of aging and gender on striatal and extrastriatal [(123)I]FP-CIT binding in Parkinson's disease
    Valtteri Kaasinen
    Division of Clinical Neurosciences, University of Turku and Turku University Hospital, Turku, Finland Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland Electronic address
    Neurobiol Aging 36:1757-63. 2015
  2. doi request reprint Differences in striatal dopamine transporter density between tremor dominant and non-tremor Parkinson's disease
    Valtteri Kaasinen
    Division of Clinical Neurosciences, University of Turku and Turku University Hospital, POB 52, 20521, Turku, Finland
    Eur J Nucl Med Mol Imaging 41:1931-7. 2014
  3. doi request reprint Seasonality of striatal dopamine synthesis capacity in Parkinson's disease
    Valtteri Kaasinen
    Department of Neurology, University of Turku and Turku University Hospital, Turku, Finland
    Neurosci Lett 530:80-4. 2012
  4. doi request reprint Effects of intravenous placebo with glucose expectation on human basal ganglia dopaminergic function
    Lauri T Haltia
    Department of Neurology, University of Turku, Turku, Finland
    Synapse 62:682-8. 2008
  5. doi request reprint Mesolimbic dopamine release is linked to symptom severity in pathological gambling
    Juho Joutsa
    Department of Neurology, University of Turku and Turku University Hospital, Turku, Finland
    Neuroimage 60:1992-9. 2012
  6. ncbi request reprint Effects of intravenous glucose on dopaminergic function in the human brain in vivo
    Lauri T Haltia
    Department of Neurology, University of Turku, Turku, Finland
    Synapse 61:748-56. 2007
  7. ncbi request reprint Substantial thalamostriatal dopaminergic defect in Unverricht-Lundborg disease
    Miikka Korja
    Department of Neurology, Turku University Hospital, Turku, Finland
    Epilepsia 48:1768-73. 2007
  8. doi request reprint Increased medial orbitofrontal [18F]fluorodopa uptake in Parkinsonian impulse control disorders
    Juho Joutsa
    Department of Neurology, University of Turku and Turku University Hospital, Turku, Finland
    Mov Disord 27:778-82. 2012
  9. doi request reprint Reduced striatal dopamine synthesis capacity is associated with symptoms of depression in patients with de novo unmedicated Parkinson's disease
    Juho Joutsa
    Division of Clinical Neurosciences, Turku University Hospital and University of Turku, Turku, Finland Turku PET Centre, Turku University Hospital and University of Turku, Turku, Finland
    J Parkinsons Dis 3:325-9. 2013
  10. ncbi request reprint Dopaminergic effects of caffeine in the human striatum and thalamus
    Valtteri Kaasinen
    Department of Neurology, University of Turku, PO Box 52, FIN 20521, Turku, Finland
    Neuroreport 15:281-5. 2004

Collaborators

Detail Information

Publications26

  1. doi request reprint Effects of aging and gender on striatal and extrastriatal [(123)I]FP-CIT binding in Parkinson's disease
    Valtteri Kaasinen
    Division of Clinical Neurosciences, University of Turku and Turku University Hospital, Turku, Finland Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland Electronic address
    Neurobiol Aging 36:1757-63. 2015
    ..Women have higher caudate nucleus dopamine transporter binding compared with men in both normal and degenerated dopamine systems. ..
  2. doi request reprint Differences in striatal dopamine transporter density between tremor dominant and non-tremor Parkinson's disease
    Valtteri Kaasinen
    Division of Clinical Neurosciences, University of Turku and Turku University Hospital, POB 52, 20521, Turku, Finland
    Eur J Nucl Med Mol Imaging 41:1931-7. 2014
    ..The present study investigated striatal dopamine transporter (DAT) binding characteristics in a large sample of patients with and without tremor...
  3. doi request reprint Seasonality of striatal dopamine synthesis capacity in Parkinson's disease
    Valtteri Kaasinen
    Department of Neurology, University of Turku and Turku University Hospital, Turku, Finland
    Neurosci Lett 530:80-4. 2012
    ..Findings concerning season of birth further suggest that there may be gestational or perinatal seasonal factors, which influence dopaminergic function in adulthood...
  4. doi request reprint Effects of intravenous placebo with glucose expectation on human basal ganglia dopaminergic function
    Lauri T Haltia
    Department of Neurology, University of Turku, Turku, Finland
    Synapse 62:682-8. 2008
    ..g., amphetamine and glucose). Also, they suggest that the DA release in the ventral striatum mediates placebo responses in the context of glucose expectation...
  5. doi request reprint Mesolimbic dopamine release is linked to symptom severity in pathological gambling
    Juho Joutsa
    Department of Neurology, University of Turku and Turku University Hospital, Turku, Finland
    Neuroimage 60:1992-9. 2012
    ..Human reward-seeking gambling behavior, and especially pathological gambling, has been presumed to be modulated by brain dopamine...
  6. ncbi request reprint Effects of intravenous glucose on dopaminergic function in the human brain in vivo
    Lauri T Haltia
    Department of Neurology, University of Turku, Turku, Finland
    Synapse 61:748-56. 2007
    ....
  7. ncbi request reprint Substantial thalamostriatal dopaminergic defect in Unverricht-Lundborg disease
    Miikka Korja
    Department of Neurology, Turku University Hospital, Turku, Finland
    Epilepsia 48:1768-73. 2007
    ..Myoclonus, the characteristic symptom in ULD, suggests that dopamine neurotransmission may be involved in the pathophysiology of ULD. Our purpose was to examine brain dopaminergic function in ULD patients...
  8. doi request reprint Increased medial orbitofrontal [18F]fluorodopa uptake in Parkinsonian impulse control disorders
    Juho Joutsa
    Department of Neurology, University of Turku and Turku University Hospital, Turku, Finland
    Mov Disord 27:778-82. 2012
    ..Impulse control disorders (ICDs) occur frequently in PD patients...
  9. doi request reprint Reduced striatal dopamine synthesis capacity is associated with symptoms of depression in patients with de novo unmedicated Parkinson's disease
    Juho Joutsa
    Division of Clinical Neurosciences, Turku University Hospital and University of Turku, Turku, Finland Turku PET Centre, Turku University Hospital and University of Turku, Turku, Finland
    J Parkinsons Dis 3:325-9. 2013
    ....
  10. ncbi request reprint Dopaminergic effects of caffeine in the human striatum and thalamus
    Valtteri Kaasinen
    Department of Neurology, University of Turku, PO Box 52, FIN 20521, Turku, Finland
    Neuroreport 15:281-5. 2004
    ..81, p = 0.03). The findings indicate that caffeine has effects on dopaminergic neurotransmission in the human brain, which may be differential in the striatum and the thalamus...
  11. doi request reprint Effects of dopamine agonist dose and gender on the prognosis of impulse control disorders in Parkinson's disease
    Juho Joutsa
    Department of Neurology, University of Turku and Turku University Hospital, Finland
    Parkinsonism Relat Disord 18:1079-83. 2012
    ..There have been no previous large-scale prospective studies investigating predictive and prognostic factors of these disorders...
  12. ncbi request reprint Expectation of caffeine induces dopaminergic responses in humans
    Valtteri Kaasinen
    Department of Neurology, University of Turku, PO Box 52, FIN 20521, Turku, Finland
    Eur J Neurosci 19:2352-6. 2004
    ..The results therefore suggest that caffeine and placebo caffeine may share some dopaminergic mechanisms of action...
  13. doi request reprint Acute hormonal changes following intravenous glucose challenge in lean and obese human subjects
    Lauri T Haltia
    Department of Neurology, University of Turku, Finland
    Scand J Clin Lab Invest 70:275-80. 2010
    ..v. glucose bolus on insulin, leptin, ghrelin, peptide YY (PYY), free fatty acids (FFA), glucagon and glucagon-like peptide-1 (GLP-1) concentrations together with self-reported satiety ratings in lean and obese human subjects...
  14. ncbi request reprint Insular dopamine D2 receptors and novelty seeking personality in Parkinson's disease
    Valtteri Kaasinen
    Department of Neurology, University of Turku, Finland
    Mov Disord 19:1348-51. 2004
    ..The results provide further support for a relationship between novelty seeking and insular D2 receptors. They indicate that the association is cross-cultural, independent of age, and unaffected by dopaminergic degeneration...
  15. doi request reprint Impulse control disorders and depression in Finnish patients with Parkinson's disease
    Juho Joutsa
    Department of Neurology, University of Turku and Turku University Hospital, Finland
    Parkinsonism Relat Disord 18:155-60. 2012
    ..However, the frequencies have been investigated mainly in patients from secondary or tertiary care centers, and thus, the prevalence rates in general community are not known...
  16. ncbi request reprint Functional imaging studies of dopamine system and cognition in normal aging and Parkinson's disease
    Valtteri Kaasinen
    Department of Neurology, University of Turku, PO Box 52, FIN 20521, Turku, Finland
    Neurosci Biobehav Rev 26:785-93. 2002
    ..In particular, the focus is on describing and discussing the relationships between aging, cognition and the dopaminergic system in healthy subjects and in patients with Parkinson's disease...
  17. doi request reprint Intravenous ethanol increases dopamine release in the ventral striatum in humans: PET study using bolus-plus-infusion administration of [(11)C]raclopride
    Sargo Aalto
    1 Turku PET Centre, University of Turku, Turku, Finland 2 Department of Psychology, Abo Akademi University, Abo, Finland
    J Cereb Blood Flow Metab 35:424-31. 2015
    ..87, P=0.003) and putamen (r=-0.74; P=0.02). These results confirm that ethanol induces rapid DA release in the limbic striatum, which can be reliably estimated using the B/I method in one imaging session. ..
  18. doi request reprint Diagnostic accuracy of parkinsonism syndromes by general neurologists
    Juho Joutsa
    Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland Department of Neurology, Satakunta Central Hospital, Pori, Finland Electronic address
    Parkinsonism Relat Disord 20:840-4. 2014
    ..Movement disorder specialists can achieve a high level of accuracy when clinically diagnosing parkinsonism syndromes. However, data about the diagnostic accuracy among general neurologists is limited...
  19. doi request reprint Impulse control disorders are associated with multiple psychiatric symptoms in Parkinson's disease
    Elina Jaakkola
    Division of Clinical Neurosciences, Turku University Hospital and University of Turku, Turku, Finland Turku PET Centre, Turku University Hospital and University of Turku, Turku, Finland
    J Parkinsons Dis 4:507-15. 2014
    ..Impulse control disorders can have serious adverse consequences to the life of a patient with Parkinson's disease. Although impulse control disorders are common, a possible psychiatric comorbidity has not been fully characterized...
  20. ncbi request reprint Regional effects of donepezil and rivastigmine on cortical acetylcholinesterase activity in Alzheimer's disease
    Valtteri Kaasinen
    Department of Neurology, University of Turku, Turku, Finland
    J Clin Psychopharmacol 22:615-20. 2002
    ..We hypothesize that the clinical improvement in behavioral and attentional symptoms of AD due to AChE inhibitors is associated with the frontal AChE inhibition...
  21. ncbi request reprint Personality traits and striatal 6-[18F]fluoro-L-dopa uptake in healthy elderly subjects
    Valtteri Kaasinen
    Department of Neurology, University of Turku, P O Box 52, FIN 20521 Turku, Finland
    Neurosci Lett 332:61-4. 2002
    ..The results indicate that the previous positive findings concerning harm avoidance and (18)F-dopa uptake in Parkinson's disease are disease-related, and that they can not be generalized to healthy individuals...
  22. doi request reprint Extensive abnormality of brain white matter integrity in pathological gambling
    Juho Joutsa
    Department of Neurology, University of Turku, Turku, Finland Turku PET Centre, University of Turku, Finland
    Psychiatry Res 194:340-6. 2011
    ..The results suggest that pathological gambling is associated with extensive lower integrity of several brain white matter tracts. The diffusion abnormality closely resembles previous findings in individuals with substance addictions...
  23. ncbi request reprint Brain white matter expansion in human obesity and the recovering effect of dieting
    Lauri T Haltia
    Department of Neurology, University of Turku, P O Box 52, FIN 20521 Turku, Finland
    J Clin Endocrinol Metab 92:3278-84. 2007
    ..We hypothesized that possible differences seen in the brains of obese subjects would disappear or diminish after an intensive dieting period...
  24. doi request reprint Mortality in Parkinson's disease is not associated with the severity of early dopaminergic defect
    Juha T Järvelä
    Division of Clinical Neurosciences, Turku University Hospital and University of Turku, Turku, Finland Electronic address
    Parkinsonism Relat Disord 20:894-7. 2014
    ..The objective of this study was to determine whether the initial degree of hypodopaminergic defect, as measured by 6-[(18)F]fluoro-L-DOPA positron emission tomography (FDOPA-PET), can predict patient survival...
  25. pmc Parallel appearance of compulsive behaviors and artistic creativity in Parkinson's disease
    Juho Joutsa
    Department of Neurology, University of Turku and Turku University Hospital, Turku, Finland
    Case Rep Neurol 4:77-83. 2012
    ....
  26. doi request reprint Brain ¹⁸F-FDG and ¹¹C-PiB PET findings in two siblings with FTD/ALS associated with the C9ORF72 repeat expansion
    Mika H Martikainen
    a Department of Neurology, University of Turku and Turku University Hospital, Turku, Finland
    Neurocase 20:150-7. 2014
    ..His sister was diagnosed with FTD, and the C9ORF72 expansion was detected in both siblings. We conclude that ¹¹C-PiB PET imaging may help the early differential diagnosis between AD and FTD, including C9FTD/ALS...