Research Topics
Species | Marja JylhaSummaryAffiliation: University of Tampere Country: Finland Publications
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Detail Information
Publications
Dementia as a determinant of social and health service use in the last two years of life 1996-2003Leena Forma
School of Health Sciences, FI 33014 University of Tampere, Finland
BMC Geriatr 11:14. 2011..The aim of this study was to assess the effects of dementia and year of death (1998-2003) on health and social service use in the last two years of life among old people...
Self-rated health showed a graded association with frequently used biomarkers in a large population sampleMarja Jylha
University of Tampere, School of Public Health, Medisiinarinkatu 3, Tampere, FIN 33014, Finland
J Clin Epidemiol 59:465-71. 2006..We investigated the association of frequently used biomarkers with self-rated health, and the role of these biomarkers in the association of self-rated health with mortality...
What is self-rated health and why does it predict mortality? Towards a unified conceptual modelMarja Jylha
School of Public Health, University of Tampere, Finland
Soc Sci Med 69:307-16. 2009..Self-rated health lies at the cross-roads of culture and biology, therefore a collaborative effort between different disciplines can only improve our understanding of this key measure of health status...- Interleukin-1 receptor antagonist, interleukin-6, and C-reactive protein as predictors of mortality in nonagenarians: the vitality 90+ studyMarja Jylha
Tampere School of Public Health, FIN 33014 University of Tampere, Finland
J Gerontol A Biol Sci Med Sci 62:1016-21. 2007..We investigated blood levels of C-reactive protein (CRP), interleukin-6 (IL-6), interleukin-1 receptor antagonist (IL-1ra), and their combinations as predictors of mortality in nonagenarians... - Old age and loneliness: cross-sectional and longitudinal analyses in the Tampere Longitudinal Study on AgingMarja Jylha
School of Public Health, University of Tampere, Finland
Can J Aging 23:157-68. 2004..In conclusion, only a minority of older people continuously suffer from loneliness. Loneliness does increase with age, not because of age per se, but because of increasing disability and decreasing social integration... - [Good and bad aspects of the medicalisation of aging]Marja Jylha
Tampereen yliopiston terveystieteen laitos, 33014 Tampereen yliopisto
Duodecim 119:1886-92. 2003 - Apolipoprotein E genotype is related to plasma levels of C-reactive protein and lipids and to longevity in nonagenariansRiikka Rontu
Laboratory of Atherosclerosis Genetics, Tampere University Hospital, Centre for Laboratory Medicine and Department of Clinical Chemistry, University of Tampere, Medical School, Finland
Clin Endocrinol (Oxf) 64:265-70. 2006..The aim of the present study was to establish whether APOE genotype is related to plasma concentrations of CRP and lipids, or longevity among nonagenarians... - Circulating cell-free DNA is associated with mortality and inflammatory markers in nonagenarians: the Vitality 90+ StudyJuulia Jylhävä
Department of Microbiology and Immunology, School of Medicine, University of Tampere, Finland
Exp Gerontol 47:372-8. 2012..The cf-DNA concentration could thus represent a novel biomarker for systemic inflammation and mortality in the elderly... - Inflammation, adiposity, and mortality in the oldest oldInna Lisko
Gerontology Research Center, School of Health Sciences, University of Tampere, Finland
Rejuvenation Res 15:445-52. 2012..We investigated the association of inflammatory markers with body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) in nonagenarians, and the combined effects of BMI, WC, WHR, and inflammatory status on mortality... - Among nonagenarians, congruence between self-rated and proxy-rated health was low but both predicted mortalityMerja Vuorisalmi
Tampere School of Health Sciences, University of Tampere, Medisiinarinkatu 3, Tampere 33014, Finland
J Clin Epidemiol 65:553-9. 2012.... - Inflammatory markers and physical performance among nonagenariansKristina Tiainen
Tampere School of Public Health, University of Tampere, FI 33014 University of Tampere, Finland
J Gerontol A Biol Sci Med Sci 65:658-63. 2010..This study examined associations between inflammatory markers and physical performance among nonagenarians... - Municipal variation in health and social service use in the last 2 years of life among old peopleLeena Forma
School of Health Sciences, University of Tampere, Finland
Scand J Public Health 39:361-70. 2011..To describe and analyse municipal differences in health and social service use among old people in the last 2 years of life... - Global self-rated health data from a longitudinal study predicted mortality better than comparative self-rated health in old ageMerja Vuorisalmi
Tampere School of Public Health and Centre of Advanced Study, University of Tampere, Finland
J Clin Epidemiol 58:680-7. 2005..Two SRH measures are examined, an age group comparative question and a global question with no explicit point of reference... - Interleukin-6 modulates plasma cholesterol and C-reactive protein concentrations in nonagenariansTerho Lehtimaki
Laboratory of Atherosclerosis Genetics, Tampere University Hospital, Tampere, Finland
J Am Geriatr Soc 53:1552-8. 2005..To establish whether the relationship between interleukin-6 (IL-6) and plasma lipid and C-reactive protein (CRP) concentrations is different in Finnish nonagenarians than in middle-aged subjects with lower inflammatory status... - Complement factor H 402His variant confers an increased mortality risk in Finnish nonagenarians: the Vitality 90+ studyJuulia Jylhävä
Department of Microbiology and Immunology, Medical School, University of Tampere, FIN 33014 Tampere, Finland
Exp Gerontol 44:297-9. 2009..016). We propose that the increased mortality is inflammation-related and mediated by aberrant complement regulation by the CFH 402His variant... - IL-7 concentration is increased in nonagenarians but is not associated with markers of T cell immunosenescenceSaara Marttila
Department of Microbiology and Immunology, School of Medicine, University of Tampere, Finland
Exp Gerontol 46:1000-2. 2011..These results suggest that the IL-7 levels in nonagenarians do not have an inhibitory effect on the development of immunosenescence; rather they are associated with increased inflammation... - The impact of dementia on care transitions during the last two years of lifeMari Aaltonen
School of Health Sciences, University of Tampere, Tampere FIN 33014, Finland
Age Ageing 41:52-7. 2012..Dementia is one of the main challenges to our health and social care. This study compares the number and timing of transitions between care settings in the last 2 years of life among older people with and without dementia... - Comparative vs global self-rated health: associations with age and functional abilityMerja Vuorisalmi
School of Public Health, University of Tampere, 33014 Tampere, Finland
Aging Clin Exp Res 18:211-7. 2006..The focus is on differences between these questions and on the consequences which these differences have in research... - Old people, alcohol use and mortality. A ten-year prospective studyEija Tolvanen
Tampere School of Public Health, University of Tampere, Finland
Aging Clin Exp Res 17:426-33. 2005..The aim of this study was to examine the association of drinking frequencies and beverage types with all-cause mortality among old people... - Body mass index, waist circumference, and waist-to-hip ratio as predictors of mortality in nonagenarians: the Vitality 90+ StudyInna Lisko
School of Health Sciences, University of Tampere, Finland
J Gerontol A Biol Sci Med Sci 66:1244-50. 2011..The purpose of this study was to investigate the association of BMI, waist circumference (WC), and waist-to-hip ratio with mortality in nonagenarians... - Expression profiling of immune-associated genes in peripheral blood mononuclear cells reveals baseline differences in co-stimulatory signalling between nonagenarians and younger controls: the vitality 90+ studyJuulia Jylhävä
Department of Microbiology and Immunology, University of Tampere, Finland
Biogerontology 11:671-7. 2010..Further research is, however, required to establish the relationship between these changes and the mechanisms of immunosenescence... - Cytomegalovirus (CMV)-dependent and -independent changes in the aging of the human immune system: a transcriptomic analysisTaru Kuparinen
Department of Microbiology and Immunology, School of Medicine, 33014 University of Tampere, Tampere, Finland
Exp Gerontol 48:305-12. 2013..Taken together, these results indicate that the CMV-dependent and CMV-independent changes in the aging of the immune system are fundamentally different... - Associations between inflammatory markers, candidate polymorphisms and physical performance in older Danish twinsKristina Tiainen
School of Health Sciences, University of Tampere, FI 33014 Tampere, Finland
Exp Gerontol 47:109-15. 2012..However, other gene variations than the candidate gene polymorphisms studied here seem to explain the major part of the genetic proportion of this association... - Aging-associated increase in indoleamine 2,3-dioxygenase (IDO) activity appears to be unrelated to the transcription of the IDO1 or IDO2 genes in peripheral blood mononuclear cellsSaara Marttila
Department of Microbiology and Immunology, The School of Medicine, University of Tampere, Finland
Immun Ageing 8:9. 2011..abstract:.. - Aging is associated with quantitative and qualitative changes in circulating cell-free DNA: the Vitality 90+ studyJuulia Jylhävä
Department of Microbiology and Immunology, Medical School, University of Tampere, Biokatu 6, FIN Medi 33014, Finland
Mech Ageing Dev 132:20-6. 2011..In nonagenarians, the quality of cf-DNA appeared similar in the original and follow-up samples. We propose that some, as yet uncharacterized, aspects of aging are reflected in the appearance of cf-DNA... - Use of hospitals at age 90. A population-based studySirkka Goebeler
Department of Forensic Medicine, Medical School, University of Tampere, Bldg B, FIN 33014 Tampere, Finland
Arch Gerontol Geriatr 39:93-102. 2004..2%. People aged 90 are an important group of hospital users. In the future, hospitals need to be prepared to provide adequate care for the most common diseases affecting the growing population of the oldest-old... - Always one step behind: husbands' narratives about taking care of their demented wivesTapio Kirsi
University of Tampere, Finland
Health (London) 8:159-81. 2004.... - IgA levels are predictors of mortality in Finnish nonagenariansMikko Hurme
Department of Microbiology and Immunology, University of Tampere Medical School and Tampere University Hospital, Finland
Mech Ageing Dev 126:829-31. 2005..These data imply that elevated serum IgA level, i.e. indicator of intestinal inflammation and/or defect in mucosal defence, is a strong mortality predicting factor... - Age and closeness of death as determinants of health and social care utilization: a case-control studyLeena Forma
Tampere School of Public Health, University of Tampere, Finland
Eur J Public Health 19:313-8. 2009..We used case-control design to compare utilization of health and social services between older decedents and survivors, and to identify the respective impact of age and closeness of death on the utilization of services... - Circadian activity rhythm in demented and non-demented nursing-home residents measured by telemetric actigraphyPaula Paavilainen
Tampere School of Public Health, University of Tampere, Tampere, Finland
J Sleep Res 14:61-8. 2005.... - Are IADLs comparable across countries? Sociodemographic associates of harmonized IADL measuresSuvi Nikula
University of Tampere, School of Public Health, Tampere, Finland
Aging Clin Exp Res 15:451-9. 2003..The focus of this report is to examine the comparability of IADLs across countries and to study the association of IADLs with age, gender and socioeconomic status, and the scalability of the measure... - Medical history, cognitive status and mobility at the age of 90. A population-based study in Tampere, FinlandSirkka Goebeler
School of Public Health, University of Tampere, Tampere, Finland
Aging Clin Exp Res 15:154-61. 2003..We studied the population of people born in 1907-1910 and living in the city of Tampere (Finland) at the age 90 (N=916, 79.4% women, 20.6% men); 71.7% of the population lived in the community and 28.3% in institutions... - Is there successful aging for nonagenarians? The vitality 90+ studyLily Nosraty
Gerontology Research Center and School of Health Sciences, 33014 University of Tampere, Tampere, Finland
J Aging Res 2012:868797. 2012..Age-sensitive approaches would help us better understand the potential of successful aging among individuals who already have success in longevity... - Self-reported medical history and self-rated health at age 90. Agreement with medical recordsSirkka Goebeler
School of Public Health, University of Tampere, Tampere, Finland
Aging Clin Exp Res 19:213-9. 2007..We ascertained whether the self-reported medical history and self-rated health of 90-year-olds would be in agreement with their medical records... - Urinary incontinence in a Finnish population aged 70 and over. Prevalence of types, associated factors and self-reported treatmentsMaria Nuotio
Vaasa City Hospital, University of Tampere, Finland
Scand J Prim Health Care 21:182-7. 2003..To describe the prevalence, associated factors and self-reported treatments of different types of incontinence in a random older population...