Research Topics
| Hanna JokinenSummaryAffiliation: University of Helsinki Country: Finland Publications
| Collaborators
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Detail Information
Publications
Incident lacunes influence cognitive decline: the LADIS studyH Jokinen
Memory Research Unit, Department of Neurology, University of Helsinki, Helsinki, Finland
Neurology 76:1872-8. 2011..This study investigated whether incident lacunes on MRI determine longitudinal cognitive change in elderly subjects with WML...- Brain atrophy accelerates cognitive decline in cerebral small vessel disease: the LADIS studyH Jokinen
Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
Neurology 78:1785-92. 2012..To examine the independent contributions and combined interactions of medial temporal lobe atrophy (MTA), cortical and subcortical atrophy, and white matter lesion (WML) volume in longitudinal cognitive performance... - Callosal tissue loss parallels subtle decline in psychomotor speed. a longitudinal quantitative MRI study. The LADIS StudyHanna Jokinen
Department of Neurology, Helsinki University Central Hospital Helsinki, Finland
Neuropsychologia 50:1650-5. 2012..The adverse effect of CC tissue loss on psychomotor function may be driven by altered interhemispheric information transfer between homologous cortical areas... - Longitudinal cognitive decline in subcortical ischemic vascular disease--the LADIS StudyHanna Jokinen
Department of Psychology, University of Helsinki, Helsinki, Finland
Cerebrovasc Dis 27:384-91. 2009..The aim of the study was to investigate the longitudinal cognitive performance and incident dementia in subjects with and without SIVD in a sample of older adults with white matter lesions... - MRI-defined subcortical ischemic vascular disease: baseline clinical and neuropsychological findings. The LADIS StudyHanna Jokinen
Department of Psychology, University of Helsinki, Helsinki, Finland
Cerebrovasc Dis 27:336-44. 2009..The purpose of the study was to describe the clinical and cognitive characteristics of the MRI-defined SIVD in a mixed sample of functionally independent elderly subjects with WML... 
Medial temporal lobe atrophy and memory deficits in elderly stroke patientsH Jokinen
Department of Psychology, University of Helsinki, Helsinki, Finland
Eur J Neurol 11:825-32. 2004..The most vulnerable domains are memory and visuospatial functions, whereas verbal and executive functions seem to be unrelated to MTA...
White matter hyperintensities as a predictor of neuropsychological deficits post-strokeH Jokinen
Department of Neurology, Helsinki University Central Hospital, P O Box 302, FIN 00029 HUS, Helsinki, Finland
J Neurol Neurosurg Psychiatry 76:1229-33. 2005..The purpose of this study was to explore how the severity and location of WMHs predict neuropsychological test performance in the context of other brain lesions in elderly stroke patients...- Cognitive profile of subcortical ischaemic vascular diseaseH Jokinen
Department of Psychology, University of Helsinki, Helsinki, Finland
J Neurol Neurosurg Psychiatry 77:28-33. 2006..The aim of this study is to describe in detail the neuropsychological characteristics of patients with SIVD from a large well defined stroke cohort... - Corpus callosum atrophy is associated with mental slowing and executive deficits in subjects with age-related white matter hyperintensities: the LADIS StudyHanna Jokinen
Department of Psychology, University of Helsinki, Helsinki, Finland
J Neurol Neurosurg Psychiatry 78:491-6. 2007..Previous research has indicated that corpus callosum atrophy is associated with global cognitive decline in neurodegenerative diseases, but few studies have investigated specific cognitive functions... - Post-stroke delirium in relation to dementia and long-term mortalitySusanna Melkas
Department of Neurology, Helsinki University Central Hospital and Department of Neurological Sciences, University of Helsinki, Helsinki, Finland
Int J Geriatr Psychiatry 27:401-8. 2012..We aimed to investigate whether delirium is associated with increased risk of post-stroke dementia and long-term mortality once confounding is taken into account... - Comparison of the Alzheimer's Disease Assessment Scale Cognitive Subscale and the Vascular Dementia Assessment Scale in differentiating elderly individuals with different degrees of white matter changes. The LADIS StudyRaija Ylikoski
Memory Research Unit, Department of Neurology, University of Helsinki, Helsinki, Finland
Dement Geriatr Cogn Disord 24:73-81. 2007..The objective of this study was to compare the results of the two scales among subjects with various degrees of white matter hyperintensities (WMHs)... - White matter lesions are related to impaired instrumental activities of daily living poststrokeTarja Ilona Pohjasvaara
Department of Neurology, Helsinki Medical Imaging Center, Helsinki University Central Hospital, Helsinki, Finland
J Stroke Cerebrovasc Dis 16:251-8. 2007..We sought to examine the role of WMLs and their extent, in regard to basic ADL, instrumental ADL (IADL), and cognitive functions, in a large well-defined cohort examined 3 months after an ischemic stroke... - Depression-executive dysfunction syndrome relates to poor poststroke survivalSusanna Melkas
Department of Neurology, Helsinki University Central Hospital, Finland
Am J Geriatr Psychiatry 18:1007-16. 2010..The aim of this study was to investigate the influence of poststroke depression and executive dysfunction on long-term survival after acute stroke... - Poststroke dementia predicts poor survival in long-term follow-up: influence of prestroke cognitive decline and previous strokeS Melkas
Department of Neurology, Helsinki University Central Hospital, POB 300, 00029 HUS, Finland
J Neurol Neurosurg Psychiatry 80:865-70. 2009..The aim of this study was to investigate the influence of poststroke dementia on long-term survival after acute stroke and also to assess the possible influence of prestroke cognitive decline and previous stroke on this relationship... - Association of gait and balance disorders with age-related white matter changes: the LADIS studyH Baezner
Mannheim University Hospital, University of Heidelberg, Department of Neurology, Theodor Kutzer Ufer, D 68135 Mannheim, Germany
Neurology 70:935-42. 2008..We aimed at determining the influence of ARWMC on different objective measures of gait and balance... - Reliability and sensitivity of visual scales versus volumetry for evaluating white matter hyperintensity progressionA A Gouw
Alzheimer Center, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
Cerebrovasc Dis 25:247-53. 2008..However, the most suitable method for measuring WMH progression has not been established yet. We compared the reliability and sensitivity of cross-sectional and longitudinal visual scales with volumetry for measuring WMH progression... - On the etiology of incident brain lacunes: longitudinal observations from the LADIS studyAlida A Gouw
Alzheimer Center, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
Stroke 39:3083-5. 2008..We investigated regional differences in MRI characteristics and risk factor profiles of incident lacunes over a 3-year period... - Progression of white matter hyperintensities and incidence of new lacunes over a 3-year period: the Leukoaraiosis and Disability studyAlida A Gouw
Department of Neurology, Alzheimer Center and Image Analysis Center, Vrije Universiteit Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands
Stroke 39:1414-20. 2008..We studied the natural course of white matter hyperintensities (WMH) and lacunes, the main MRI representatives of small vessel disease, over time and evaluated possible predictors for their development... - Segmentation of age-related white matter changes in a clinical multi-center studyTim B Dyrby
Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark
Neuroimage 41:335-45. 2008..Expert knowledge not available to the neural networks was a minor source of discrepancy, while variation in MR scan quality constituted the largest source of error...