Jiang M, Osterlund P, Westenius V, Guo D, Poranen M, Bamford D, et al. Efficient inhibition of avian and seasonal influenza A viruses by a virus-specific Dicer-substrate siRNA swarm in human monocyte-derived macrophages and dendritic cells. J Virol. 2018;: pubmed publisher
..The wide antiviral spectrum makes the virus-specific siRNA swarm a potentially efficient treatment modality against both avian and seasonal influenza viruses. ..
Jiang M, Ã–sterlund P, Fagerlund R, Rios D, Hoffmann A, Poranen M, et al. MAP kinase p38Î± regulates type III interferon (IFN-Î»1) gene expression in human monocyte-derived dendritic cells in response to RNA stimulation. J Leukoc Biol. 2015;97:307-20 pubmed publisher
He F, Melen K, Maljanen S, Lundberg R, Jiang M, Osterlund P, et al. Ebolavirus protein VP24 interferes with innate immune responses by inhibiting interferon-?1 gene expression. Virology. 2017;509:23-34 pubmed publisher
..These results emphasize the importance of VP24 in EBOV infection cycle, making VP24 as an excellent target for drug development. ..