Hannu Jarvelainen

Summary

Affiliation: University of Turku
Country: Finland

Publications

  1. doi request reprint Pivotal role for decorin in angiogenesis
    Hannu Jarvelainen
    Department of Medical Biochemistry and Genetics, University of Turku, Turku, Finland Department of Medicine, Division of Endocrinology, Turku University Hospital, Turku, Finland Electronic address
    Matrix Biol 43:15-26. 2015
  2. pmc Differential expression of decorin by human malignant and benign vascular tumors
    Henriikka H Salomäki
    Turku University Central Hospital, Department of Medicine, Kiinamyllynkatu 4 8, FI 20520 Turku, Finland
    J Histochem Cytochem 56:639-46. 2008
  3. ncbi request reprint [A young women with hypochromic microcytotic anemia unresponsive to iron therapy]
    Hannu Jarvelainen
    TYKS n sisätautien klinikka 20520 Turku
    Duodecim 120:80-3. 2004
  4. pmc Extracellular matrix molecules: potential targets in pharmacotherapy
    Hannu Jarvelainen
    Department of Medicine, Turku University Hospital, Kiinamyllynkatu 4 8, FI 20520 Turku, Finland
    Pharmacol Rev 61:198-223. 2009
  5. ncbi request reprint A role for decorin in cutaneous wound healing and angiogenesis
    Hannu Jarvelainen
    Department of Medicine, University of Turku, Turku, Finland
    Wound Repair Regen 14:443-52. 2006
  6. pmc Localization of decorin gene expression in normal human breast tissue and in benign and malignant tumors of the human breast
    Pia Boström
    Department of Pathology, Turku University Hospital, University of Turku, Kiinamyllynkatu 4 8, 20520 Turku, Finland
    Histochem Cell Biol 139:161-71. 2013
  7. pmc Lack of decorin expression by human bladder cancer cells offers new tools in the therapy of urothelial malignancies
    Annele Sainio
    Department of Medical Biochemistry and Genetics, University of Turku, Turku, Finland
    PLoS ONE 8:e76190. 2013
  8. doi request reprint The expression and distribution of group IIA phospholipase A2 in human colorectal tumours
    Tuulia Avoranta
    Department of Oncology and Radiotherapy, University of Turku and Turku University Hospital, Savitehtaankatu 1 PB 52, 20521, Turku, Finland
    Virchows Arch 457:659-67. 2010
  9. ncbi request reprint Cellular distribution and contribution of cyclooxygenase COX-2 to diabetogenesis in NOD mouse
    Cheng Luo
    Juvenile Diabetes Research Foundation FDRF Center for Prevention of Type 1 Diabetes in Finland, University of Turku, Turku, Finland
    Cell Tissue Res 310:169-75. 2002
  10. ncbi request reprint Inhibition of COX-2 aggravates neutrophil migration and pneumocyte apoptosis in surfactant-depleted rat lungs
    Heikki Lukkarinen
    Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, FIN 20520 Turku, Finland
    Pediatr Res 59:412-7. 2006

Collaborators

Detail Information

Publications18

  1. doi request reprint Pivotal role for decorin in angiogenesis
    Hannu Jarvelainen
    Department of Medical Biochemistry and Genetics, University of Turku, Turku, Finland Department of Medicine, Division of Endocrinology, Turku University Hospital, Turku, Finland Electronic address
    Matrix Biol 43:15-26. 2015
    ....
  2. pmc Differential expression of decorin by human malignant and benign vascular tumors
    Henriikka H Salomäki
    Turku University Central Hospital, Department of Medicine, Kiinamyllynkatu 4 8, FI 20520 Turku, Finland
    J Histochem Cytochem 56:639-46. 2008
    ..Decorin certainly provides a usable biomarker for distinguishing between benign and malignant vascular tumors in patients...
  3. ncbi request reprint [A young women with hypochromic microcytotic anemia unresponsive to iron therapy]
    Hannu Jarvelainen
    TYKS n sisätautien klinikka 20520 Turku
    Duodecim 120:80-3. 2004
  4. pmc Extracellular matrix molecules: potential targets in pharmacotherapy
    Hannu Jarvelainen
    Department of Medicine, Turku University Hospital, Kiinamyllynkatu 4 8, FI 20520 Turku, Finland
    Pharmacol Rev 61:198-223. 2009
    ..In the future, agents and compounds targeting directly the ECM will significantly advance the treatment of various human diseases, even those for which efficient therapies are not yet available...
  5. ncbi request reprint A role for decorin in cutaneous wound healing and angiogenesis
    Hannu Jarvelainen
    Department of Medicine, University of Turku, Turku, Finland
    Wound Repair Regen 14:443-52. 2006
    ..Thus, regulated production of decorin may serve as an excellent therapeutic approach for modifying impaired wound healing and harmful foreign body reactions...
  6. pmc Localization of decorin gene expression in normal human breast tissue and in benign and malignant tumors of the human breast
    Pia Boström
    Department of Pathology, Turku University Hospital, University of Turku, Kiinamyllynkatu 4 8, 20520 Turku, Finland
    Histochem Cell Biol 139:161-71. 2013
    ..Our study also shows that transduction of decorin in decorin-negative human breast cancer cells markedly modulates the growth pattern of these cells...
  7. pmc Lack of decorin expression by human bladder cancer cells offers new tools in the therapy of urothelial malignancies
    Annele Sainio
    Department of Medical Biochemistry and Genetics, University of Turku, Turku, Finland
    PLoS ONE 8:e76190. 2013
    ..Thus, decorin gene delivery offers new potential therapeutic tools in urothelial malignancies...
  8. doi request reprint The expression and distribution of group IIA phospholipase A2 in human colorectal tumours
    Tuulia Avoranta
    Department of Oncology and Radiotherapy, University of Turku and Turku University Hospital, Savitehtaankatu 1 PB 52, 20521, Turku, Finland
    Virchows Arch 457:659-67. 2010
    ..The protein is also found in the apoptotic cells, necrosis, peritumoural mucosa and in the invasive front of carcinomas...
  9. ncbi request reprint Cellular distribution and contribution of cyclooxygenase COX-2 to diabetogenesis in NOD mouse
    Cheng Luo
    Juvenile Diabetes Research Foundation FDRF Center for Prevention of Type 1 Diabetes in Finland, University of Turku, Turku, Finland
    Cell Tissue Res 310:169-75. 2002
    ..The effects of celecoxib on INS-1E cells suggest that PGE(2) and other downstream products of COX-2 may contribute to the regulation of insulin release from the beta-cells...
  10. ncbi request reprint Inhibition of COX-2 aggravates neutrophil migration and pneumocyte apoptosis in surfactant-depleted rat lungs
    Heikki Lukkarinen
    Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, FIN 20520 Turku, Finland
    Pediatr Res 59:412-7. 2006
    ..These results suggest that specific inhibitors of COX-2 should be used cautiously in association with surfactant-deficient lung injuries...
  11. ncbi request reprint Angiotensin II receptor inhibition prevents pneumocyte apoptosis in surfactant-depleted rat lungs
    Heikki P Lukkarinen
    Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland
    Pediatr Pulmonol 39:349-58. 2005
    ..The results suggest that increased epithelial apoptosis in surfactant-deficient lungs is mediated by ANG II receptor (specifically, subtype 1) action...
  12. ncbi request reprint Angiotensin II receptor blockade inhibits pneumocyte apoptosis in experimental meconium aspiration
    Heikki Lukkarinen
    Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, FIN 20014 Turku, Finland
    Pediatr Res 55:326-33. 2004
    ..Apoptotic cell death is further connected with ANG II receptor action in the meconium-contaminated lung tissue...
  13. ncbi request reprint Lung epithelial cells undergo apoptosis in neonatal respiratory distress syndrome
    Heikki P Lukkarinen
    Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland
    Pediatr Res 53:254-9. 2003
    ..These results suggest that significant epithelial apoptosis is present in the lungs of newborn infants with fatal RDS and that this apoptosis may be attenuated by steroid administration...
  14. ncbi request reprint Tissue inhibitor of metalloproteinases 4 (TIMP4) is involved in inflammatory processes of human cardiovascular pathology
    Ilpo Koskivirta
    Department of Medical Biochemistry and Molecular Biology, University of Turku, Turku, Finland
    Histochem Cell Biol 126:335-42. 2006
    ..In conclusion, the data demonstrate upregulation of TIMP4 in human cardiovascular disorders exhibiting inflammation, suggesting its future use as a novel systemic marker for vascular inflammation...
  15. doi request reprint Tissue inhibitor of matrix metalloproteinases 4 (TIMP4) in a population of young adults: relations to cardiovascular risk markers and carotid artery intima-media thickness. The Cardiovascular Risk in Young Finns Study
    Mervi Oikonen
    Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, 20520 Turku, Finland
    Scand J Clin Lab Invest 72:540-6. 2012
    ....
  16. doi request reprint Hyperglycemic conditions modulate connective tissue reorganization by human vascular smooth muscle cells through stimulation of hyaluronan synthesis
    Annele Sainio
    Department of Medical Biochemistry and Genetics, University of Turku, FI 20520 Turku, Finland
    Glycobiology 20:1117-26. 2010
    ....
  17. ncbi request reprint Overexpression of decorin by rat arterial smooth muscle cells enhances contraction of type I collagen in vitro
    Hannu Jarvelainen
    Department of Medicine, University of Turku, Finland
    Arterioscler Thromb Vasc Biol 24:67-72. 2004
    ..We examined the hypothesis that decorin regulates ECM volume by stimulating cell-mediated contraction of collagen-rich ECMs...
  18. doi request reprint Epigenetic Silencing of the Key Antioxidant Enzyme Catalase in Karyotypically Abnormal Human Pluripotent Stem Cells
    Mikko Konki
    Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku, Finland
    Sci Rep 6:22190. 2016
    ..Our findings provide novel insight into the mechanisms associated with spontaneous transformation of human pluripotent stem cells towards malignant fate. The same mechanisms may control the genomic stability of cells in somatic tissues. ..