Research Topics
| M IsohanniSummaryAffiliation: University of Oulu Country: Finland Publications
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Detail Information
Publications
Childhood and adolescent predictors of schizophrenia in the Northern Finland 1966 birth cohort--a descriptive life-span modelM Isohanni
Department of Psychiatry, University of Oulu, Finland
Eur Arch Psychiatry Clin Neurosci 250:311-9. 2000..This is done by reviewing the Northern Finland 1966 Birth Cohort, its scientific activities (publications and work in progress) and selected literature...- Developmental precursors of psychosisMatti Isohanni
Department of Psychiatry, Faculty of Medicine, University of Oulu, Oulu University Central Hospital, PO Box 5000, FIN 90014 Oulu, Finland
Curr Psychiatry Rep 6:168-75. 2004..No powerful risk factor, premorbid sign, or risk indicator has been identified that is useful for prediction of psychoses in the general population... - The persistence of developmental markers in childhood and adolescence and risk for schizophrenic psychoses in adult life. A 34-year follow-up of the Northern Finland 1966 birth cohortMatti Isohanni
Department of Psychiatry, University of Oulu, P O Box 5000, 90014 Oulu, Finland
Schizophr Res 71:213-25. 2004..These findings are in line with the hypothesis that a neural diathesis is present during postnatal brain development before schizophrenia. This supports the longitudinal dimension and life span models of schizophrenia... - Predictors of schizophrenia: evidence from the Northern Finland 1966 Birth Cohort and other sourcesMatti Isohanni
Department of Psychiatry, University of Oulu, PO Box 5000, Finland
Br J Psychiatry Suppl 48:s4-7. 2005..Subtle motor, emotional, cognitive and behavioural abnormalities are often present in apparently healthy individuals who later develop schizophrenia, suggesting that some aspects of causation are established before overt psychosis... - Early developmental milestones in adult schizophrenia and other psychoses. A 31-year follow-up of the Northern Finland 1966 Birth CohortM Isohanni
Department of Psychiatry, University of Oulu, PL5000, 90014, Oulu, Finland
Schizophr Res 52:1-19. 2001..These developmental effects were not seen for non-psychotic outcomes. The findings support hypotheses regarding psychosis as having a developmental dimension with precursors apparent in early life... - [Control to the number of PhD thesis among medical doctors]Matti Isohanni
Oulun yliopisto ja OYS:n psykiatrian klinikka, Oulu
Duodecim 121:2315-6. 2005 - Is a child's risk of early onset schizophrenia increased in the highest social class?T Makikyro
Department of Psychiatry, University of Oulu, Finland
Schizophr Res 23:245-52. 1997..The results suggest that in some families in Northern Finland, a father's professional advancement, often linked to mental disorder, may be one determinant of an increased risk of schizophrenia in the child... - Hospital-treated psychiatric disorders in adults with a single-parent and two-parent family background: a 28-year follow-up of the 1966 Northern Finland Birth CohortT Makikyro
Department of Psychiatry, University of Oulu, Finland
Fam Process 37:335-44. 1998..It is likely that a combination of the single-parent family and psychosocial and/or genetic risk may influence the development of these disorders... - Schizophrenia as a long-term outcome of pregnancy, delivery, and perinatal complications: a 28-year follow-up of the 1966 north Finland general population birth cohortP B Jones
Department of Psychiatry, University of Nottingham, Oulu, Finland
Am J Psychiatry 155:355-64. 1998..The 1966 North Finland general population birth cohort was studied to determine whether abnormalities during pregnancy, delivery, and the neonatal period are associated with adult-onset schizophrenia... - Early developmental differences between DSM-III-R schizophrenics treated with clozapine and typical neurolepticsT Makikyro
Department of Psychiatry, University of Oulu, Finland
J Psychiatr Res 32:105-10. 1998..These early developmental characteristics did not predict clinical severity of schizophrenia in adulthood... - Birth order and risk for schizophrenia: a 31-year follow-up of the Northern Finland 1966 Birth CohortL Kemppainen
Department of Psychiatry, University of Oulu, Finland
Acta Psychiatr Scand 104:148-52. 2001..Theoretical explanations may arise from biological factors unidentified here and/or psychological stressors linked with these positions... - Serum lipids in schizophrenia and other functional psychoses: a general population northern Finland 1966 birth cohort surveyK Saari
Department of Psychiatry, University of Oulu, Oulu, Finland
Acta Psychiatr Scand 110:279-85. 2004..To compare fasting serum lipid concentrations of subjects with schizophrenia with a comparison group... - Outcome and its predictors in schizophrenia within the Northern Finland 1966 Birth CohortE Lauronen
Department of Psychiatry, University of Oulu, P O Box 5000, FIN 90014 University of Oulu, Finland
Eur Psychiatry 22:129-36. 2007..We report clinical and social outcomes of schizophrenia in the longitudinal, population-based Northern Finland 1966 Birth Cohort, and describe associated demographic, developmental and illness-related factors... - Educational consequences of mental disorders treated in hospital. A 31-year follow-up of the Northern Finland 1966 Birth CohortI Isohanni
Department of Psychiatry, University of Oulu and Oulu Polytechnic, Finland
Psychol Med 31:339-49. 2001..Failure to complete higher education may contribute to the 'social exclusion' of the mentally ill through reduced opportunities in later occupational life and failure to accumulate social capital... - The one-child family and violent criminality: a 31-year follow-up study of the Northern Finland 1966 Birth CohortL Kemppainen
Department of Psychiatry, University of Oulu, Peltolantie 5, 90210 Oulu, Finland
Am J Psychiatry 158:960-2. 2001..The authors studied whether being an only child was associated with criminality in adulthood and, secondly, if parental factors increased the putative risk... - Community placement of long-stay psychiatric patients in northern FinlandS Räsänen
Department of Psychiatry, University of Oulu, Finland
Psychiatr Serv 51:383-5. 2000..The results showed that long-stay patients are dependent on considerable support. Alternative residential facilities have made deinstitutionalization possible... - Infant motor development is associated with adult cognitive categorisation in a longitudinal birth cohort studyG K Murray
Department of Psychiatry, University of Cambridge, UK, and Muurola Hospital, Hospital District of Lapland, Finland
J Child Psychol Psychiatry 47:25-9. 2006..We hypothesised that the age of learning to stand in infancy would be associated with adult executive function and that the association would be apparent throughout the range of abilities, rather than confined to extremes... - Is grand multiparity associated with offsprings' hospital-treated mental disorders? A 28-year follow-up of the North Finland 1966 birth cohortL Kemppainen
Department of Psychiatry, University of Oulu, Finland
Soc Psychiatry Psychiatr Epidemiol 35:104-8. 2000..e. a mother who has undergone six or more deliveries) is at increased risk of perinatal complications, but it is not known whether or not GMP status is associated with child's adulthood mental disorders... - Psychiatric disorders and their predictors in young adulthood in FinlandJ Veijola
University of Oulu, Department of Psychiatry, Finland
Int J Circumpolar Health 57:195-201. 1998..Especially childhood predictors of mental disorders are reviewed... 
Negative symptoms in schizophrenia: a reviewJ Makinen
Department of Psychiatry, University of Oulu, Finland
Nord J Psychiatry 62:334-41. 2008..However, according to clinical experience, when treating negative symptoms, the best effect is achieved by optimizing the dose of medication and by complementing it with psychosocial therapies...- The use of videoconferencing for telepsychiatry in FinlandM L Mielonen
Department of Psychiatry, Oulu University Hospital, Finland
J Telemed Telecare 4:125-31. 1998..5 (SD 1.0). Preliminary results with telepsychiatry in Finland have been promising. Interactive videoconferencing provides an easy, fast and relatively inexpensive method of providing psychiatric services over long distances... - Prevalence of alcohol use disorders in schizophrenia--a systematic review and meta-analysisJ Koskinen
Department of Psychiatry, University of Oulu and Oulu University Hospital, Oulu, Finland
Acta Psychiatr Scand 120:85-96. 2009..Our aim was to present recent studies of alcohol use disorders (AUDs) in patients with schizophrenia, estimate overall prevalence and characteristics affecting the prevalence of AUDs... - Good school performance is a risk factor of suicide in psychoses: a 35-year follow up of the Northern Finland 1966 Birth CohortA Alaräisänen
Department of Psychiatry, University of Oulu, Oulu, Finland
Acta Psychiatr Scand 114:357-62. 2006..Our aim was to analyse the relationship between good school performance and risk of suicide in the Northern Finland 1966 Birth Cohort, especially in psychoses... - Gender differences in treatment and outcome in a therapeutic community ward, with special reference to schizophrenic patientsS Räsänen
Department of Psychiatry, University of Oulu, Finland
Psychiatry 62:235-49. 1999..With its greater degree of interaction and positive experiences, the therapeutic community model may help psychotic male patients in facing their age- and gender-specific life-span challenges... - Parental separation at birth and depression in adulthood: a long-term follow-up of the Finnish Christmas Seal Home ChildrenJ Veijola
Department of Psychiatry, University of Oulu, Finland
Psychol Med 34:357-62. 2004..On the other hand, separation from the parents at birth was not found to be strongly associated with severe adulthood depression... - The use of bibliometric data in evaluating research on therapeutic community for addictions and in psychiatryP Nieminen
Medical Computing Unit, University of Oulu, Finland
Subst Use Misuse 32:555-70. 1997..This may lead to the smoother use of traditional quantitative research strategies and standard publication channels than in other psychiatric therapeutic community studies... - Psychiatric inpatient care planning via telemedicineM L Mielonen
Department of Psychiatry, University Hospital of Oulu, Finland
J Telemed Telecare 6:152-7. 2000..At 50 care consultations per year, a remote municipality would save about FM117,000... - Peer review--still the well-functioning quality control and enhancer in scientific researchMatti Isohanni
Acta Psychiatr Scand 112:165-6. 2005 - Infant developmental milestones: a 31-year follow-upAnja Taanila
University of Oulu, Department of Public Health Science and General Practice, PO Box 5000, 90014 Oulu, Finland
Dev Med Child Neurol 47:581-6. 2005..4 times greater in faster developers than in slow developers. In conclusion, those who develop faster during their first year of life tend to attain higher levels of education in adolescence and adulthood... - Poor premorbid school performance is associated with later cigarette smoking among schizophrenia patientsKaisa Riala
Department of Psychiatry, University of Oulu, Box 5000, FIN 90014 University of Oulu, Finland
Psychiatry Res 137:137-41. 2005..Poor school performance might represent premorbid nicotinergic dysfunction associated with cognitive deficits in future smokers among schizophrenia patients compared with those who remained non-smokers... - Statistical methodologies in psychopharmacology: a reviewPentti Nieminen
Medical Informatics Group, University of Oulu, Finland
Hum Psychopharmacol 21:195-203. 2006.... - Patterns of psychiatric hospitalizations in schizophrenic psychoses within the Northern Finland 1966 Birth CohortJouko Miettunen
Department of Psychiatry, University of Oulu, PO Box 5000, FIN 90014, Finland
Nord J Psychiatry 60:286-93. 2006..Although short hospitalization is recommended by several guidelines, there may be a group of patients with schizophrenic psychoses in which too short a hospitalization may lead to inadequate treatment response... - [Other mental disorders presenting together with schizophrenia]Hannu Koponen
OYS:n psykiatrian klinikka, Lapin sairaanhoitopiiri, psykiatrian toimialue Totontie 9 97145 Totonvaara
Duodecim 119:43-9. 2003 - Vitamin D supplementation during the first year of life and risk of schizophrenia: a Finnish birth cohort studyJohn McGrath
Department of Psychiatry, University of Cambridge, Cambridge, UK
Schizophr Res 67:237-45. 2004..The aim of this study was to explore the association between the use of vitamin D supplements during the first year of life and risk of developing schizophrenia... - Non-participation may bias the results of a psychiatric survey: an analysis from the survey including magnetic resonance imaging within the Northern Finland 1966 Birth CohortMarianne Haapea
Department of Psychiatry, University of Oulu, Oulu, Finland
Soc Psychiatry Psychiatr Epidemiol 42:403-9. 2007..Furthermore, we wanted to explore other associative factors expected to affect non-participation... - Videoconferencing in child and adolescent psychiatry in Finland--an inadequately exploited resourceLilli Pesämaa
Clinic of Child Psychiatry, Department of Pediatrics, Oulu University Hospital, Finland
J Telemed Telecare 13:125-9. 2007..The implementation of videoconferencing seems to depend more on the activity of service providers than on the number of people involved... - Temporary parental separation at birth and substance use disorder in adulthood. A long-term follow-up of the Finnish Christmas Seal Home ChildrenJuha Veijola
Dept of Psychiatry, University and University Hospital of Oulu, P O Box 5000, 90014 Oulu, Finland
Soc Psychiatry Psychiatr Epidemiol 43:11-7. 2008..Adversities in the early mother-infant relation pose a hypothetical risk for addiction. We studied the association between very early separation and later development of substance use disorder... - Associations between early development and outcome in schizophrenia--A 35-year follow-up of the Northern Finland 1966 Birth CohortErika Jaaskelainen
Department of Psychiatry, University of Oulu, Finland, P O Box 5000, 90014 University of Oulu, Finland
Schizophr Res 99:29-37. 2008..We conclude that risk factors for schizophrenia are not necessarily prognostic factors... - How to use bibliometric methods in evaluation of scientific research? An example from Finnish schizophrenia researchJohanna Koskinen
Department of Psychiatry, University of Oulu and Oulu University Hospital, Finland
Nord J Psychiatry 62:136-43. 2008..According to our experience, these methods can be used as an evaluation instrument in research together with other methods, such as expert opinions and panels... - Predictors of schizophrenia--a reviewPirjo Maki
Department of Psychiatry, University of Oulu, PO Box 5000, FIN 90014 University of Oulu, Finland
Br Med Bull 73:1-15. 2005.... - Recovery from schizophrenic psychoses within the northern Finland 1966 Birth CohortErika Lauronen
Department of Psychiatry, University of Oulu, P O Box 5000, FIN 90014, Oulu, Finland
J Clin Psychiatry 66:375-83. 2005..Because of widely disparate findings from follow-up studies, the likelihood of recovery from schizophrenia remains controversial. We report the extent of recovery from schizophrenia in a population-based cohort... 
Is initiation of smoking associated with the prodromal phase of schizophrenia?Kaisa Riala
Department of Psychiatry, University of Oulu, Finland
J Psychiatry Neurosci 30:26-32. 2005..Our goal was to study this putative temporal relation among patients with schizophrenia...- Weight gain and glucose and lipid metabolism disturbances during antipsychotic medication: a reviewHannu Koponen
Department of Psychiatry, University of Oulu, Oulu, Finland
Eur Arch Psychiatry Clin Neurosci 252:294-8. 2002.... - Criminality in the offspring of antenatally depressed mothers: a 33-year follow-up of the Northern Finland 1966 Birth CohortPirjo Maki
Department of Psychiatry, University of Oulu, P O Box 5000, FIN 90014 Oulu, Finland
J Affect Disord 74:273-8. 2003..No epidemiological studies have been reported on the association between mothers' antenatal depression and criminality in their offspring... - Reasons for the diagnostic discordance between clinicians and researchers in schizophrenia in the Northern Finland 1966 Birth CohortKristiina Moilanen
Dept of Psychiatry, University of Oulu, P O 5000, 90014 University of Oulu, Finland
Soc Psychiatry Psychiatr Epidemiol 38:305-10. 2003..This poses a challenge to psychiatric research. We studied the reasons for diagnostic discordance between clinicians and researchers... - Parental separation at birth and criminal behaviour in adulthood--a long-term follow-up of the Finnish Christmas Seal Home childrenPirjo Maki
Dept of Psychiatry, University of Oulu and University Hospital of Oulu, P O Box 5000, 90014 University of Oulu, Finland
Soc Psychiatry Psychiatr Epidemiol 38:354-9. 2003..Parental absence has been connected with later criminality. We studied the association between very early separation and criminality in a unique data set... - Schizophrenia in the offspring of antenatally depressed mothers: a 31-year follow-up of the Northern Finland 1966 Birth CohortPirjo Maki
Schizophr Res 66:79-81. 2004 - Maternal separation at birth and schizophrenia--a long-term follow-up of the Finnish Christmas Seal Home ChildrenPirjo Maki
Department of Psychiatry, University of Oulu, PO Box 5000, FIN 90014 Oulu, Finland
Schizophr Res 60:13-9. 2003..Problems in the early mother-infant relation pose a hypothetical risk factor of schizophrenia. We studied the association between very early separation and later development of schizophrenia or other psychoses in a unique data set... - Childhood central nervous system infections and risk for schizophreniaHannu Koponen
Department of Psychiatry, University of Oulu, PO Box 5000, 90014 Oulu, Finland
Eur Arch Psychiatry Clin Neurosci 254:9-13. 2004..Our results suggest that viral CNS infections during childhood may have a role as a risk factor for schizophrenia. Their role may be modest at the population level due to their relative rareness... - Hyperlipidemia in persons using antipsychotic medication: a general population-based birth cohort studyKaisa Saari
Department of Psychiatry, University of Oulu, 90014 Oulu, Finland
J Clin Psychiatry 65:547-50. 2004..The results indicate an elevated risk of hyperlipidemia in persons using antipsychotic medication independent of the other risk factors assessed... - Links between creativity and mental disorderErika Lauronen
Department of Psychiatry, University of Oulu, Finland
Psychiatry 67:81-98. 2004..In conclusion, evidence exists to support some form of association between creativity and mental disorder, but the direction of any causal link remains obscure... - Socio-demographic and clinical predictors of occupational status in schizophrenic psychoses--follow-up within the Northern Finland 1966 Birth CohortJouko Miettunen
Department of Psychiatry, University of Oulu, P O Box 5000, 90014 Oulun yliopisto, Finland
Psychiatry Res 150:217-25. 2007..Based on our findings, those who were single at time of their onset of illness probably need most support to retain their contacts to work life... - Predictors of female criminality: findings from the Northern Finland 1966 birth cohortLiisa Kemppainen
Department of Psychiatry, University of Oulu, Finland
J Am Acad Child Adolesc Psychiatry 41:854-9. 2002..Thus there is a need for original studies into the perinatal contribution to the etiology of female offending... - Low educational performance is associated with drunk driving: a 31-year follow-up of the northern Finland 1966 birth cohortKaisa Riala
Department of Psychiatry, University of Oulu, Box 5000, FIN-90014 University of Oulu, Oulu Polytechnic, Oulu, Finland
Alcohol Alcohol 38:219-23. 2003..4) and 7.0 (95% CI 3.3-14.8), respectively. CONCLUSIONS: These results are unlikely to be directly causal; however, educational failures seem to be part of the complex causal pathway to drunk driving and even to alcohol-related disorders... - Teenage smoking and substance use as predictors of severe alcohol problems in late adolescence and in young adulthoodKaisa Riala
Department of Psychiatry, University of Oulu, Box 5000, Oulu FIN 90014, Finland
J Adolesc Health 35:245-54. 2004..To study the association between adolescent alcohol use, smoking, other substance use, and later substance-use-related problems in a large general population sample in Northern Finland... - Videoconferencing in child and adolescent telepsychiatry: a systematic review of the literatureLilli Pesämaa
Clinic of Child Psychiatry, Department of Paediatrics, Oulu University Hospital, Finland
J Telemed Telecare 10:187-92. 2004..Well designed and properly controlled trials are required to evaluate the clinical value of this promising method in child psychiatry, where there is a constantly increasing need for services... - Implementation of a telepsychiatric network in northern FinlandMarja-Leena Mielonen
Department of Psychiatry, University Hospital of Oulu, Finland
Curr Probl Dermatol 32:132-40. 2003 - How should a scientific team be effectively formed and managedMatti Isohanni
University of Oulu, Department of Psychiatry, PO Box 5000, FI-90014 Oulu, Finland
Nord J Psychiatry 56:157-62. 2002..In this article, some essential organizational and psychological aspects of the scientific team are described and discussed. In addition, practical guidelines on forming, working and managing a research team are presented... - Higher serum triglyceride levels in early-onset schizophreniaKaisa Saari
Am J Psychiatry 161:176. 2004 - Statistical methodology in general psychiatric journalsJouko Miettunen
Department of Psychiatry, University of Oulu, PO Box 5000, FIN-90014, Finland
Nord J Psychiatry 56:223-8. 2002.... - What is a top scientist like?Matti Isohanni
Nord J Psychiatry 60:189. 2006