Reetta Huttunen

Summary

Affiliation: University of Tampere
Country: Finland

Publications

  1. ncbi request reprint Current concepts in the diagnosis of blood stream infections. Are novel molecular methods useful in clinical practice?
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, Box 2000, FI 33521 Tampere, Finland University of Tampere Medical School, University of Tampere, Tampere, Finland Electronic address
    Int J Infect Dis 17:e934-8. 2013
  2. doi request reprint Obesity and nosocomial infections
    R Huttunen
    University of Tampere Medical School, University of Tampere, Finland
    J Hosp Infect 85:8-16. 2013
  3. doi request reprint Case fatality associated with a hypervirulent strain in patients with culture-positive Clostridium difficile infection: a retrospective population-based study
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, Box 2000, FI 33521 Tampere, Finland
    Int J Infect Dis 16:e532-5. 2012
  4. doi request reprint Apoptosis markers soluble Fas (sFas), Fas Ligand (FasL) and sFas/FasL ratio in patients with bacteremia: a prospective cohort study
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, Box 2000, FI 33521 Tampere, Finland
    J Infect 64:276-81. 2012
  5. doi request reprint New concepts in the pathogenesis, diagnosis and treatment of bacteremia and sepsis
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, Box 2000, FI 33521 Tampere, Finland
    J Infect 63:407-19. 2011
  6. pmc High plasma level of long pentraxin 3 (PTX3) is associated with fatal disease in bacteremic patients: a prospective cohort study
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, Tampere, Finland
    PLoS ONE 6:e17653. 2011
  7. doi request reprint Plasma level of soluble urokinase-type plasminogen activator receptor as a predictor of disease severity and case fatality in patients with bacteraemia: a prospective cohort study
    R Huttunen
    Department of Internal Medicine, Tampere University Hospital, University of Tampere Medical School, University of Tampere, Tampere, Finland
    J Intern Med 270:32-40. 2011
  8. doi request reprint Smoking and the outcome of infection
    R Huttunen
    Department of Internal Medicine, Tampere University Hospital, University of Tampere Medical School, Tampere, Finland
    J Intern Med 269:258-69. 2011
  9. doi request reprint High activity of indoleamine 2,3 dioxygenase enzyme predicts disease severity and case fatality in bacteremic patients
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, University of Tampere Medical School, University of Tampere, Tampere, Finland
    Shock 33:149-54. 2010
  10. doi request reprint Endothelial nitric oxide synthase G894T (GLU298ASP) polymorphism is associated with hypotension in patients with E. coli bacteremia but not in bacteremia caused by a gram-positive organism
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, Tampere, Finland
    Shock 31:448-53. 2009

Detail Information

Publications16

  1. ncbi request reprint Current concepts in the diagnosis of blood stream infections. Are novel molecular methods useful in clinical practice?
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, Box 2000, FI 33521 Tampere, Finland University of Tampere Medical School, University of Tampere, Tampere, Finland Electronic address
    Int J Infect Dis 17:e934-8. 2013
    ..Gram-stain information in combination with clinical data is an underestimated, underused, rapid, and economical means of assessing the etiology of blood stream infection. ..
  2. doi request reprint Obesity and nosocomial infections
    R Huttunen
    University of Tampere Medical School, University of Tampere, Finland
    J Hosp Infect 85:8-16. 2013
    ..The prevention of healthcare-associated infections (HCAIs) is a major goal in modern healthcare. Intrinsic, patient-related factors may contribute to the risk of HCAIs...
  3. doi request reprint Case fatality associated with a hypervirulent strain in patients with culture-positive Clostridium difficile infection: a retrospective population-based study
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, Box 2000, FI 33521 Tampere, Finland
    Int J Infect Dis 16:e532-5. 2012
    ..The epidemiology of C. difficile infection (CDI) is changing, with evidence of increased incidence and severity. The first patient with a hypervirulent strain type in Pirkanmaa Hospital District, Finland was reported in September 2008...
  4. doi request reprint Apoptosis markers soluble Fas (sFas), Fas Ligand (FasL) and sFas/FasL ratio in patients with bacteremia: a prospective cohort study
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, Box 2000, FI 33521 Tampere, Finland
    J Infect 64:276-81. 2012
    ..Monitoring apoptosis on a routine basis in septic patients has proved challenging. We here studied the prognostic value of apoptosis markers human soluble Fas (sFas), Fas ligand (FasL) and sFas/FasL ratio in patients with bacteremia...
  5. doi request reprint New concepts in the pathogenesis, diagnosis and treatment of bacteremia and sepsis
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, Box 2000, FI 33521 Tampere, Finland
    J Infect 63:407-19. 2011
    ..Treatment options currently under way are targeted to enhance immune responses, rebalance the regulation of the dysregulated immune system, remove endotoxin and block/inhibit apoptosis...
  6. pmc High plasma level of long pentraxin 3 (PTX3) is associated with fatal disease in bacteremic patients: a prospective cohort study
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, Tampere, Finland
    PLoS ONE 6:e17653. 2011
    ..Like C-reactive protein (CRP), it belongs to the pentraxin superfamily. Recent studies indicate that high levels of PTX3 may be associated with mortality in sepsis. The prognostic value of plasma PTX3 in bacteremic patients is unknown...
  7. doi request reprint Plasma level of soluble urokinase-type plasminogen activator receptor as a predictor of disease severity and case fatality in patients with bacteraemia: a prospective cohort study
    R Huttunen
    Department of Internal Medicine, Tampere University Hospital, University of Tampere Medical School, University of Tampere, Tampere, Finland
    J Intern Med 270:32-40. 2011
    ..Previous studies indicate that a high plasma concentration of the soluble form of the receptor (suPAR) predicts poor outcome in infectious diseases...
  8. doi request reprint Smoking and the outcome of infection
    R Huttunen
    Department of Internal Medicine, Tampere University Hospital, University of Tampere Medical School, Tampere, Finland
    J Intern Med 269:258-69. 2011
    ..g. potential dose-dependent effects and the interactions between smoking and other environmental factors that may affect the course of infectious diseases) remain to be established...
  9. doi request reprint High activity of indoleamine 2,3 dioxygenase enzyme predicts disease severity and case fatality in bacteremic patients
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, University of Tampere Medical School, University of Tampere, Tampere, Finland
    Shock 33:149-54. 2010
    ..The data in this report demonstrate that IDO activity is markedly increased in bacteremia patients, constituting an independent predictor of severe disease and case fatality...
  10. doi request reprint Endothelial nitric oxide synthase G894T (GLU298ASP) polymorphism is associated with hypotension in patients with E. coli bacteremia but not in bacteremia caused by a gram-positive organism
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, Tampere, Finland
    Shock 31:448-53. 2009
    ..Carriage of the T allele of the eNOS gene is a risk factor for hypotension in patients with E. coli bacteremia but not in bacteremia caused by a gram-positive organism...
  11. doi request reprint Gene-environment interaction between MBL2 genotype and smoking, and the risk of gram-positive bacteraemia
    R Huttunen
    Department of Internal Medicine, Tampere University Hospital, Tampere, Finland
    Scand J Immunol 68:438-44. 2008
    ....
  12. pmc Obesity and smoking are factors associated with poor prognosis in patients with bacteraemia
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, PL 2000, FIN 33521 Tampere, Finland
    BMC Infect Dis 7:13. 2007
    ..Bacteraemia is still a major cause of case fatality in all age groups. Our aim was to identify the major underlying conditions constituting risk factors for case fatality in bacteraemia patients...
  13. pmc Fatal outcome in bacteremia is characterized by high plasma cell free DNA concentration and apoptotic DNA fragmentation: a prospective cohort study
    Reetta Huttunen
    Department of Internal Medicine, Tampere University Hospital, Tampere, Finland
    PLoS ONE 6:e21700. 2011
    ..Recent studies have shown that apoptosis plays a critical role in the pathogenesis of sepsis. High plasma cell free DNA (cf-DNA) concentrations have been shown to be associated with sepsis outcome. The origin of cf-DNA is unclear...
  14. ncbi request reprint Polymorphism of the C-reactive protein gene is associated with mortality in bacteraemia
    Carita Eklund
    Department of Microbiology and Immunology, University of Tampere Medical School, Finland
    Scand J Infect Dis 38:1069-73. 2006
    ..These results suggest that mortality from Streptococcus pneumoniae may be associated with polymorphism of the promoter region of the CRP gene...
  15. doi request reprint Methicillin-resistant Staphylococcus aureus epidemic restricted to one health district in Finland: a population-based descriptive study in Pirkanmaa, Finland, years 2001-2011
    Janne Laine
    Department of Internal Medicine, Tampere University Hospital, Tampere, Finland
    Scand J Infect Dis 45:45-53. 2013
    ..The incidence of methicillin-resistant Staphylococcus aureus (MRSA) has been low in the Scandinavian countries, including Finland...
  16. pmc Plasma levels of soluble urokinase-type plasminogen activator receptor associate with the clinical severity of acute Puumala hantavirus infection
    Tuula K Outinen
    Department of Internal Medicine, Tampere University Hospital, Tampere, Finland School of Medicine, University of Tampere, Tampere, Finland
    PLoS ONE 8:e71335. 2013
    ..Plasma soluble form of the receptor (suPAR) levels were evaluated as a predictor of severe Puumala hantavirus (PUUV) infection and as a possible factor involved in the pathogenesis of the disease...