H Huopio

Summary

Affiliation: University of Kuopio
Country: Finland

Publications

  1. pmc Dominantly inherited hyperinsulinism caused by a mutation in the sulfonylurea receptor type 1
    H Huopio
    Department of Pediatrics, Kuopio University Hospital, Kuopio, Finland
    J Clin Invest 106:897-906. 2000
  2. ncbi request reprint Acute insulin response tests for the differential diagnosis of congenital hyperinsulinism
    H Huopio
    Department of Pediatrics, Kuopio University Hospital, FIN 70211 Kuopio, Finland
    J Clin Endocrinol Metab 87:4502-7. 2002
  3. ncbi request reprint K(ATP) channels and insulin secretion disorders
    H Huopio
    Department of Pediatrics, Kuopio University Hospital, Kuopio 70211, Finland
    Am J Physiol Endocrinol Metab 283:E207-16. 2002
  4. ncbi request reprint A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland
    T Otonkoski
    Transplantation Laboratory, Haartman Institute, and University of Helsinki, Finland
    Diabetes 48:408-15. 1999
  5. ncbi request reprint Characterisation of new KATP-channel mutations associated with congenital hyperinsulinism in the Finnish population
    F Reimann
    Department of Clinical Biochemistry, University of Cambridge, UK
    Diabetologia 46:241-9. 2003

Detail Information

Publications5

  1. pmc Dominantly inherited hyperinsulinism caused by a mutation in the sulfonylurea receptor type 1
    H Huopio
    Department of Pediatrics, Kuopio University Hospital, Kuopio, Finland
    J Clin Invest 106:897-906. 2000
    ..In conclusion, we describe the first dominantly inherited SUR1 mutation that causes CHI in early life and predisposes to later insulin deficiency...
  2. ncbi request reprint Acute insulin response tests for the differential diagnosis of congenital hyperinsulinism
    H Huopio
    Department of Pediatrics, Kuopio University Hospital, FIN 70211 Kuopio, Finland
    J Clin Endocrinol Metab 87:4502-7. 2002
    ..Our results, however, also demonstrate the complexity of these responses and the difficulties in their interpretation...
  3. ncbi request reprint K(ATP) channels and insulin secretion disorders
    H Huopio
    Department of Pediatrics, Kuopio University Hospital, Kuopio 70211, Finland
    Am J Physiol Endocrinol Metab 283:E207-16. 2002
    ....
  4. ncbi request reprint A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland
    T Otonkoski
    Transplantation Laboratory, Haartman Institute, and University of Helsinki, Finland
    Diabetes 48:408-15. 1999
    ..This unique SUR1 mutation explains the majority of PHHI cases in Finland and is strongly associated with a severe form of the disease. These findings provide diagnostic and prognostic utility for suspected PHHI patients...
  5. ncbi request reprint Characterisation of new KATP-channel mutations associated with congenital hyperinsulinism in the Finnish population
    F Reimann
    Department of Clinical Biochemistry, University of Cambridge, UK
    Diabetologia 46:241-9. 2003
    ..The aim of this study was to analyse the functional consequences of four CHI mutations (A1457T, V1550D and L1551V in SUR1, and K67N in Kir6.2) recently identified in the Finnish population...