Matti Hillbom

Summary

Affiliation: University of Oulu
Country: Finland

Publications

  1. ncbi Alcohol and stroke: pathophysiologic mechanisms
    M Hillbom
    Department of Neurology, University Hospital of Oulu, Finland
    Neuroepidemiology 17:281-7. 1998
  2. ncbi Seizures in alcohol-dependent patients: epidemiology, pathophysiology and management
    Matti Hillbom
    Department of Neurology, Oulu University Hospital, Box 25, FIN 90029 OYS, Oulu, Finland
    CNS Drugs 17:1013-30. 2003
  3. ncbi Enoxaparin vs heparin for prevention of deep-vein thrombosis in acute ischaemic stroke: a randomized, double-blind study
    M Hillbom
    Department of Neutology, Oulu University Hospital Oulu, Finland
    Acta Neurol Scand 106:84-92. 2002
  4. ncbi [Can we afford cheap alcohol?]
    Matti Hillbom
    OYS n neurologian klinikka
    Duodecim 121:701-3. 2005
  5. doi Alcohol consumption, blood pressure, and the risk of stroke
    Matti Hillbom
    Department of Neurology, Oulu University Hospital, Box 20, Oulu 90 029 OYS, Finland
    Curr Hypertens Rep 13:208-13. 2011
  6. ncbi Recent heavy drinking of alcohol and embolic stroke
    M Hillbom
    Department of Neurology, Oulu University Central Hospital, Finland
    Stroke 30:2307-12. 1999
  7. ncbi Alcohol intake and the risk of stroke
    M Hillbom
    Department of Neurology, University Hospital of Oulu, Finland
    J Cardiovasc Risk 6:223-8. 1999
  8. ncbi Oxidants, antioxidants, alcohol and stroke
    M Hillbom
    University of Oulu, Department of Neurology, Kajaanintie 50, FIN 90220 Oulu, Finland
    Front Biosci 4:e67-71. 1999
  9. doi A population based study of outcomes after evacuation of primary supratentorial intracerebral hemorrhage
    Pekka Löppönen
    Department of Neurosurgery, Oulu University Hospital, Oulu, Finland
    Clin Neurol Neurosurg 115:1350-5. 2013
  10. doi Predictors for recurrent primary intracerebral hemorrhage: a retrospective population-based study
    Juha Huhtakangas
    Department of Neurology, Oulu University Hospital, Oulu, Finland
    Stroke 44:585-90. 2013

Collaborators

Detail Information

Publications42

  1. ncbi Alcohol and stroke: pathophysiologic mechanisms
    M Hillbom
    Department of Neurology, University Hospital of Oulu, Finland
    Neuroepidemiology 17:281-7. 1998
    ..The antiatherogenic effects of regular light-to-moderate alcohol consumption could be mediated by inhibition of low-density lipoprotein oxidation, and by elevated estrogen levels...
  2. ncbi Seizures in alcohol-dependent patients: epidemiology, pathophysiology and management
    Matti Hillbom
    Department of Neurology, Oulu University Hospital, Box 25, FIN 90029 OYS, Oulu, Finland
    CNS Drugs 17:1013-30. 2003
    ..The treatment of alcohol dependence is more important and should be prioritised before the prevention of further seizures...
  3. ncbi Enoxaparin vs heparin for prevention of deep-vein thrombosis in acute ischaemic stroke: a randomized, double-blind study
    M Hillbom
    Department of Neutology, Oulu University Hospital Oulu, Finland
    Acta Neurol Scand 106:84-92. 2002
    ..To compare the efficacy, safety, and overall risk-benefit profile of enoxaparin and unfractionated heparin (UFH) prophylaxis of venous thromboembolic complications in patients with acute ischaemic stroke...
  4. ncbi [Can we afford cheap alcohol?]
    Matti Hillbom
    OYS n neurologian klinikka
    Duodecim 121:701-3. 2005
  5. doi Alcohol consumption, blood pressure, and the risk of stroke
    Matti Hillbom
    Department of Neurology, Oulu University Hospital, Box 20, Oulu 90 029 OYS, Finland
    Curr Hypertens Rep 13:208-13. 2011
    ..Binge drinking is a significant risk factor for stroke. Hypertensive patients should be warned about the risks of alcohol and urged to avoid binge drinking because of an increased risk for all subtypes of stroke...
  6. ncbi Recent heavy drinking of alcohol and embolic stroke
    M Hillbom
    Department of Neurology, Oulu University Central Hospital, Finland
    Stroke 30:2307-12. 1999
    ..We investigated recent light, moderate, and heavy alcohol drinking and former heavy drinking as risk factors for acute ischemic brain infarction by etiological subtype of stroke...
  7. ncbi Alcohol intake and the risk of stroke
    M Hillbom
    Department of Neurology, University Hospital of Oulu, Finland
    J Cardiovasc Risk 6:223-8. 1999
    ..Several factors to explain the beneficial effect of light to moderate drinking have been proposed...
  8. ncbi Oxidants, antioxidants, alcohol and stroke
    M Hillbom
    University of Oulu, Department of Neurology, Kajaanintie 50, FIN 90220 Oulu, Finland
    Front Biosci 4:e67-71. 1999
    ..Whether a lack of antioxidants is responsible for this effect also remains to be proved. Future stroke research should focus on solving these problems...
  9. doi A population based study of outcomes after evacuation of primary supratentorial intracerebral hemorrhage
    Pekka Löppönen
    Department of Neurosurgery, Oulu University Hospital, Oulu, Finland
    Clin Neurol Neurosurg 115:1350-5. 2013
    ..To explore whether hematoma evacuation after ICH had improved short-term survival or functional outcome we conducted a retrospective observational population-based study...
  10. doi Predictors for recurrent primary intracerebral hemorrhage: a retrospective population-based study
    Juha Huhtakangas
    Department of Neurology, Oulu University Hospital, Oulu, Finland
    Stroke 44:585-90. 2013
    ..Underlying comorbidities, previous strokes, and medication may increase the risk for primary intracerebral hemorrhage (PICH) and its recurrence. The aim of this study was to determine the independent predictors for recurrent PICH...
  11. doi Direct costs of patients with stroke can be continuously monitored on a national level: performance, effectiveness, and Costs of Treatment episodes in Stroke (PERFECT Stroke) Database in Finland
    Atte Meretoja
    Department of Neurology, Helsinki University Central Hospital, P O Box 340, FI 00029 HUS, Finland
    Stroke 42:2007-12. 2011
    ..Treatment of stroke consumes a significant portion of all healthcare expenditure. We developed a system for monitoring costs from individual patient data on a national level in Finland...
  12. doi Stroke monitoring on a national level: PERFECT Stroke, a comprehensive, registry-linkage stroke database in Finland
    Atte Meretoja
    Department of Neurology, Helsinki University Central Hospital, PO Box 340, FI 00029 HUS, Finland
    Stroke 41:2239-46. 2010
    ..Comprehensive data collection on this common disease is resource-intensive, and national stroke databases often include only patients from selected hospitals. Here we describe an alternative national stroke database...
  13. ncbi The impact of functional status at three months on long-term survival after spontaneous intracerebral hemorrhage
    Pertti Saloheimo
    Department of Neurology, Oulu University Hospital, Finland
    Stroke 37:487-91. 2006
    ..Patients who survive the acute phase may run different prognoses, depending on their disability, treatment, and lifestyle. The present study was performed to find out the predictors for long-term mortality after ICH...
  14. doi Recurrent traumatic brain injury is predicted by the index injury occurring under the influence of alcohol
    Satu Winqvist
    Department of Neurology, University of Oulu, Finland
    Brain Inj 22:780-5. 2008
    ..Little is known of the role of alcohol intoxication as a risk factor for recurrent traumatic brain injuries (TBI). This study was a population-based longitudinal study to investigate this problem...
  15. doi Mild traumatic brain injury diagnosis frequently remains unrecorded in subjects with craniofacial fractures
    Jussi Puljula
    Department of Neurology, Oulu University Hospital, Finland
    Injury 43:2100-4. 2012
    ..We investigated how often TBI remains unrecorded in these subjects, and whether diagnostic accuracy has improved after the implementation of new TBI guidelines...
  16. doi Safety of low-dose subcutaneous enoxaparin for the prevention of venous thromboembolism after primary intracerebral haemorrhage
    Sami Tetri
    Department of Neurosurgery, Oulu University Hospital, Finland
    Thromb Res 123:206-12. 2008
    ..The few studies on this subject have revealed conflicting results...
  17. ncbi Traumatic brain injuries in children and young adults: a birth cohort study from northern Finland
    Satu Winqvist
    Department of Neurology, University of Oulu and Oulu University Hospital, Oulun yliopisto, Finland
    Neuroepidemiology 29:136-42. 2007
    ..This cohort provides a valuable source of data from the population born in 1966 (n = 12,058) in the 2 northernmost provinces of Finland...
  18. doi Effect of increased warfarin use on warfarin-related cerebral hemorrhage: a longitudinal population-based study
    Juha Huhtakangas
    Department of Neurology, Oulu University Hospital, Box 20, 90 029 OYS, Finland
    Stroke 42:2431-5. 2011
    ..Warfarin use has rapidly increased with the aging of the population. We investigated the temporal trends in the incidence and outcome of warfarin-related intracerebral hemorrhages (ICHs) in a defined population...
  19. ncbi Weekday distribution of head traumas in patients admitted to the emergency department of a city hospital: effects of age, gender and drinking pattern
    Jussi Puljula
    Department of Neurology, Oulu University Hospital, Oulu, Finland
    Alcohol Alcohol 42:474-9. 2007
    ..To define the alcohol-related risk for head traumas and to compare the weekly and monthly variations in alcohol consumption, and the occurrence of head traumas in a population with heavy episodic drinking as the prevailing drinking pattern...
  20. doi Impact of ischemic heart disease and atrial fibrillation on survival after spontaneous intracerebral hemorrhage
    Sami Tetri
    Department of Neurosurgery, Oulu University Hospital, Oulu, Finland
    J Neurosurg 108:1172-7. 2008
    ..Ischemic heart disease and atrial fibrillation may also increase early deaths. In the present study the authors aimed to elucidate the role of the last 2 factors...
  21. doi Hypertension and diabetes as predictors of early death after spontaneous intracerebral hemorrhage
    Sami Tetri
    Departments of Neurosurgery, Oulu University Hospital, Oulu, Finland
    J Neurosurg 110:411-7. 2009
    ..It remains unclear, however, whether hypertension and diabetes are responsible for this effect. High admission MABP and plasma glucose levels may also be markers of other factors such as stroke severity...
  22. ncbi Parental alcohol misuse is a powerful predictor for the risk of traumatic brain injury in childhood
    Satu Winqvist
    Department of Neurology, University of Oulu and Oulu University Hospital, Box 25, FIN 90029 OYS, Finland
    Brain Inj 21:1079-85. 2007
    ....
  23. doi Mortality of harmful drinkers increased after reduction of alcohol prices in northern Finland: a 10-year follow-up of head trauma subjects
    Kalle Vaaramo
    Department of Neurology, University of Oulu and Oulu University Hospital, Oulu, Finland
    Neuroepidemiology 39:156-62. 2012
    ..Alcohol-related mortality may be influenced by the level of alcohol consumption. We investigated the effect of alcohol price reduction on mortality in a cohort of 827 subjects with head injury...
  24. ncbi Alcohol intake and the pattern of trauma in young adults and working aged people admitted after trauma
    Olli Savola
    Department of Neurology, Oulu University Hospital, Oulu, Finland
    Alcohol Alcohol 40:269-73. 2005
    ..To investigate the relationship of different patterns of alcohol intake to various types of trauma...
  25. ncbi Regular aspirin-use preceding the onset of primary intracerebral hemorrhage is an independent predictor for death
    Pertti Saloheimo
    Department of Neurology, Oulu University Hospital, Finland
    Stroke 37:129-33. 2006
    ..The effect of preceding aspirin-use on outcome after ICH is poorly investigated. We investigated short-term mortality and hematoma enlargement in subjects with ICH to find the predictors for these outcomes...
  26. ncbi Thromboxane and prostacyclin biosynthesis in patients with acute spontaneous intracerebral hemorrhage
    Pertti Saloheimo
    Department of Neurology, Oulu University Central Hospital, Oulu Finland
    Thromb Res 115:367-73. 2005
    ..This marker of platelet activation has not been investigated in patients with acute spontaneous intracerebral hemorrhage (ICH)...
  27. ncbi Blood alcohol is the best indicator of hazardous alcohol drinking in young adults and working-age patients with trauma
    Olli Savola
    Department of Neurology, Oulu University Hospital, Box 25, FIN 90029, Finland
    Alcohol Alcohol 39:340-5. 2004
    ..To determine the most effective marker of hazardous alcohol drinking in trauma patients...
  28. ncbi Effects of head and extracranial injuries on serum protein S100B levels in trauma patients
    Olli Savola
    Department of Neurology, Oulu University Hospital, Oulu, Finland
    J Trauma 56:1229-34; discussion 1234. 2004
    ..Serum protein S100B determinations have been recently suggested as markers of traumatic brain injury. However, little is known about the effects of extracranial injuries on S100B levels in trauma patients...
  29. ncbi Use of aspirin, epistaxis, and untreated hypertension as risk factors for primary intracerebral hemorrhage in middle-aged and elderly people
    P Saloheimo
    Department of Neurology, Oulu University Central Hospital, Finland
    Stroke 32:399-404. 2001
    ..Other independent risk factors are untreated hypertension, previous ischemic stroke, epilepsy, and recent strenuous physical exertion. Epistaxis may be a warning sign of an increased risk for ICH in subjects using aspirin...
  30. doi Mortality from traumatic brain injury after reduction of alcohol prices: a population-based study from northern Finland
    Jussi Puljula
    Department of Neurology, Oulu University Hospital, Finland
    Scand J Public Health 41:524-30. 2013
    ..In Finland, alcohol taxes were cut by one third in 2004. This resulted in a marked increase of alcohol consumption. We investigated whether increased alcohol consumption influenced the number of fatal TBIs...
  31. ncbi Adolescents' drinking habits predict later occurrence of traumatic brain injury: 35-year follow-up of the northern Finland 1966 birth cohort
    Satu Winqvist
    Department of Neurology, University of Oulu and Oulu University Hospital, Oulu, Finland
    J Adolesc Health 39:275.e1-7. 2006
    ..To examine the relationship between adolescents' drinking habits and the risk of traumatic brain injury...
  32. ncbi Fall-related brain injuries and the risk of dementia in elderly people: a population-based study
    H Luukinen
    Department of Public Health Science and General Practice, University of Oulu, University Hospital, PB 5000, Oulu, FIN 90014 Finland
    Eur J Neurol 12:86-92. 2005
    ..68 (2.32-25.3). We conclude that fall-related TBI predicts earlier onset of dementia and the effect is especially high amongst subjects who carry the ApoE epsilon4 allele...
  33. doi Risk of dementia associated with the ApoE epsilon4 allele and falls causing head injury without explicit traumatic brain injury
    H Luukinen
    Department of Public Health Science and General Practice, University of Oulu, Unit of General Practice, Oulu University Hospital, Oulu, Finland
    Acta Neurol Scand 118:153-8. 2008
    ..The corresponding effect of falls causing HI without explicit traumatic brain injury (TBI) in association with the ApoE epsilon4 is not known...
  34. ncbi Ear oximetry: a noninvasive method for detection of patent foramen ovale: a study comparing dye dilution method and oximetry with contrast transesophageal echocardiography
    V Karttunen
    Department of Neurology, Oulu Finland University Hospital
    Stroke 32:448-53. 2001
    ..There is a need for low-cost and noninvasive methods for the detection of PFO. This study evaluates the accuracy of two simple bedside tests, the dye dilution method and ear oximetry, in the detection of PFO...
  35. ncbi Risk factors for cryptogenic ischaemic stroke
    V Karttunen
    Department of Neurology, Oulu University Central Hospital, Helsinki, Finland
    Eur J Neurol 9:625-32. 2002
    ..Several of the observed risk factors for cryptogenic brain infarction were lifestyle-associated, which emphasizes the role of health education in addition to pharmacological treatment in the prevention of stroke...
  36. doi Diagnosis and management of Marchiafava-Bignami disease: a review of CT/MRI confirmed cases
    Matti Hillbom
    Department of Neurology, Oulu University Hospital, Oulu, Finland
    J Neurol Neurosurg Psychiatry 85:168-73. 2014
    ..Our objective was to identify helpful features for differential diagnosis and assess whether any treatment can be recommended...
  37. ncbi Early predictors of post-concussion symptoms in patients with mild head injury
    O Savola
    Department of Neurology, Oulu University Hospital, Oulu, Finland
    Eur J Neurol 10:175-81. 2003
    ..The presence of skull fracture, elevated serum protein S-100B, dizziness, and headache may help the emergency room physician to identify patients at risk of PCSs and to refer them for further examination and follow-up...
  38. ncbi Factor V Leiden and prothrombin gene mutation may predispose to paradoxical embolism in subjects with patent foramen ovale
    Vesa Karttunen
    Department of Neurology, Oulu University Central Hospital, Box 25, FIN 90029 Oulu, Finland
    Blood Coagul Fibrinolysis 14:261-8. 2003
    ..140). Among the patients with prothrombotic states, Valsalva manoeuvre was common at onset of stroke. Our results support the possibility of paradoxical embolism behind strokes in patients with patent foramen ovale...
  39. doi Effectiveness of primary and comprehensive stroke centers: PERFECT stroke: a nationwide observational study from Finland
    Atte Meretoja
    Department of Neurology, Helsinki University Central Hospital, PO Box 340, FI 00029 HUS, Finland
    Stroke 41:1102-7. 2010
    ..In this study, we explored whether stroke centers fulfilling standardized Brain Attack Coalition criteria produce better patient outcomes than hospitals without stroke centers...
  40. ncbi [Severe consequences of drinking beer]
    Vesa Karttunen
    OYS n neurologian klinikka
    Duodecim 121:558-60. 2005
  41. ncbi [Acute care of intracerebral hemorrhage is improving]
    Vesa Karttunen
    OYS n neurologian klinikka
    Duodecim 121:2449-52. 2005
  42. ncbi Pattern of alcohol drinking and stroke: a comment on Mazzaglia et al
    Matti Hillbom
    Addiction 97:102-3. 2002