Anni Hienola

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. ncbi Involvement of Pleiotrophin in CNTF-mediated differentiation of the late retinal progenitor cells
    Jérôme Roger
    Laboratoire de Physiopathologie Cellulaire et Moleculaire de la Retine, UMR S 592 INSERM, Universite Pierre et Marie Curie PARIS6, Hopital Saint Antoine, Paris, France
    Dev Biol 298:527-39. 2006
  2. ncbi HB-GAM inhibits proliferation and enhances differentiation of neural stem cells
    Anni Hienola
    Neuroscience Center, Department of Biosciences and Institute of Biotechnology, University of Helsinki, Helsinki 00014, Finland
    Mol Cell Neurosci 26:75-88. 2004
  3. ncbi N-syndecan deficiency impairs neural migration in brain
    Anni Hienola
    Neuroscience Center, University of Helsinki, 00014 Helsinki, Finland
    J Cell Biol 174:569-80. 2006
  4. ncbi Syndecan-3-deficient mice exhibit enhanced LTP and impaired hippocampus-dependent memory
    Marko Kaksonen
    Laboratory of Molecular Neurobiology, Institute of Biotechnology, Department of Biosciences, University of Helsinki, Finland
    Mol Cell Neurosci 21:158-72. 2002
  5. ncbi The two thrombospondin type I repeat domains of HB-GAM display a cooperative function in N-syndecan binding and regulation of synaptic plasticity
    Erkki Raulo
    Neuroscience Center, University of Helsinki, Finland
    ScientificWorldJournal 6:406-9. 2006
  6. ncbi The two thrombospondin type I repeat domains of the heparin-binding growth-associated molecule bind to heparin/heparan sulfate and regulate neurite extension and plasticity in hippocampal neurons
    Erkki Raulo
    Neuroscience Center, University of Helsinki, Helsinki FIN 00014, Finland
    J Biol Chem 280:41576-83. 2005
  7. ncbi Sensory neurons from N-syndecan-deficient mice are defective in survival
    Mikhail Paveliev
    Institute of Biotechnology, PO Box 56, Viikki Biocenter, University of Helsinki, Helsinki FIN 00014, Finland
    Neuroreport 19:1397-400. 2008
  8. ncbi Role of heparin-binding growth-associated molecule (HB-GAM) in hippocampal LTP and spatial learning revealed by studies on overexpressing and knockout mice
    Ivan Pavlov
    Laboratory of Molecular Neurobiology, Institute of Biotechnology and Department of Biosciences, University of Helsinki, Finland
    Mol Cell Neurosci 20:330-42. 2002
  9. ncbi Glucocorticoid hormones decrease proliferation of embryonic neural stem cells through ubiquitin-mediated degradation of cyclin D1
    Maria Sundberg
    Minerva Medical Research Institute, Biomedicum Helsinki, FIN 00290 Helsinki, Finland
    J Neurosci 26:5402-10. 2006

Collaborators

Detail Information

Publications9

  1. ncbi Involvement of Pleiotrophin in CNTF-mediated differentiation of the late retinal progenitor cells
    Jérôme Roger
    Laboratoire de Physiopathologie Cellulaire et Moleculaire de la Retine, UMR S 592 INSERM, Universite Pierre et Marie Curie PARIS6, Hopital Saint Antoine, Paris, France
    Dev Biol 298:527-39. 2006
    ..Together, these results demonstrate that influence of CNTF family of cytokines on the differentiation of late retinal progenitor cell population is partially mediated by the release of Ptn...
  2. ncbi HB-GAM inhibits proliferation and enhances differentiation of neural stem cells
    Anni Hienola
    Neuroscience Center, Department of Biosciences and Institute of Biotechnology, University of Helsinki, Helsinki 00014, Finland
    Mol Cell Neurosci 26:75-88. 2004
    ..We propose that HB-GAM functions as an endogenous inhibitor of FGF-2 in stem cell proliferation in the developing cortex...
  3. ncbi N-syndecan deficiency impairs neural migration in brain
    Anni Hienola
    Neuroscience Center, University of Helsinki, 00014 Helsinki, Finland
    J Cell Biol 174:569-80. 2006
    ..Furthermore, we show that N-syndecan interacts with EGF receptor (EGFR) at the plasma membrane and is required in EGFR-induced neuronal migration...
  4. ncbi Syndecan-3-deficient mice exhibit enhanced LTP and impaired hippocampus-dependent memory
    Marko Kaksonen
    Laboratory of Molecular Neurobiology, Institute of Biotechnology, Department of Biosciences, University of Helsinki, Finland
    Mol Cell Neurosci 21:158-72. 2002
    ..We suggest that syndecan-3 acts as an important modulator of synaptic plasticity that influences hippocampus-dependent memory...
  5. ncbi The two thrombospondin type I repeat domains of HB-GAM display a cooperative function in N-syndecan binding and regulation of synaptic plasticity
    Erkki Raulo
    Neuroscience Center, University of Helsinki, Finland
    ScientificWorldJournal 6:406-9. 2006
  6. ncbi The two thrombospondin type I repeat domains of the heparin-binding growth-associated molecule bind to heparin/heparan sulfate and regulate neurite extension and plasticity in hippocampal neurons
    Erkki Raulo
    Neuroscience Center, University of Helsinki, Helsinki FIN 00014, Finland
    J Biol Chem 280:41576-83. 2005
    ..These results suggest a co-operative action of the two beta-sheet domains in the biologically relevant interaction with neuron surface heparan sulfate...
  7. ncbi Sensory neurons from N-syndecan-deficient mice are defective in survival
    Mikhail Paveliev
    Institute of Biotechnology, PO Box 56, Viikki Biocenter, University of Helsinki, Helsinki FIN 00014, Finland
    Neuroreport 19:1397-400. 2008
    ..In contrast, DRG neurons from young adult N-syndecan knockout mice exhibited normal survival. This study identifies a completely new syndecan-dependent type of signaling that regulates cell death in neurons...
  8. ncbi Role of heparin-binding growth-associated molecule (HB-GAM) in hippocampal LTP and spatial learning revealed by studies on overexpressing and knockout mice
    Ivan Pavlov
    Laboratory of Molecular Neurobiology, Institute of Biotechnology and Department of Biosciences, University of Helsinki, Finland
    Mol Cell Neurosci 20:330-42. 2002
    ..These results show that HB-GAM suppresses LTP in hippocampus and plays a role in regulation of learning-related behavior...
  9. ncbi Glucocorticoid hormones decrease proliferation of embryonic neural stem cells through ubiquitin-mediated degradation of cyclin D1
    Maria Sundberg
    Minerva Medical Research Institute, Biomedicum Helsinki, FIN 00290 Helsinki, Finland
    J Neurosci 26:5402-10. 2006
    ..In embryonic brain, dexamethasone inhibited cell proliferation of NSCs. This demonstrates that embryonic NSCs are critically influenced by glucocorticoids, which can have long-term effects in the brain...