Jussi A Hernesniemi

Summary

Affiliation: University of Tampere
Country: Finland

Publications

  1. doi request reprint Predicting sudden cardiac death using common genetic risk variants for coronary artery disease
    Jussi A Hernesniemi
    Department of Clinical Chemistry, University of Tampere, Tampere University Hospital and Fimlab Laboratories, Tampere, Finland North Karelia Central Hospital, Tikkamäentie 16, Joensuu 80210, Finland
    Eur Heart J 36:1669-75. 2015
  2. doi request reprint The prevalence of abdominal aortic aneurysm is consistently high among patients with coronary artery disease
    Jussi A Hernesniemi
    Departments of Internal Medicine and Surgery, North Karelia Central Hospital, Joensuu, Finland Electronic address
    J Vasc Surg 62:232-240.e3. 2015
  3. pmc Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta
    Jussi A Hernesniemi
    Department of Clinical Chemistry, University of Tampere, Medical School, and Tampere University Hospital, Tampere, Finland
    PLoS ONE 7:e28931. 2012
  4. ncbi request reprint Toll-like receptor 4 polymorphism is associated with coronary stenosis but not with the occurrence of acute or old myocardial infarctions
    J Hernesniemi
    Laboratory of Atherosclerosis Genetics, Department of Clinical Chemistry, Tampere University Hospital and the Medical School at the University of Tampere, Finland
    Scand J Clin Lab Invest 66:667-75. 2006
  5. doi request reprint Interleukin 18 gene promoter polymorphism: a link between hypertension and pre-hospital sudden cardiac death: the Helsinki Sudden Death Study
    Jussi A Hernesniemi
    Laboratory of Atherosclerosis Genetics, Department of Clinical Chemistry, Tampere University Hospital, Centre for Laboratory Medicine, University of Tampere, Medical School, Finn Medi 2, FI 33521 Tampere, Finland
    Eur Heart J 30:2939-46. 2009
  6. doi request reprint Interleukin-18 gene polymorphism and markers of subclinical atherosclerosis. The Cardiovascular Risk in Young Finns Study
    Jussi A Hernesniemi
    Department of Clinical Chemistry, University of Tampere and Tampere University Hospital, Finland
    Ann Med 42:223-30. 2010
  7. doi request reprint IL-18 gene polymorphism, cardiovascular mortality and coronary artery disease
    Jussi A Hernesniemi
    Laboratory of Atherosclerosis Genetics, Department of Clinical Chemistry, Tampere University Hospital, Centre for Laboratory Medicine, Tampere, Finland Medical School, University of Tampere, Tampere, Finland
    Eur J Clin Invest 40:994-1001. 2010
  8. ncbi request reprint Toll-like receptor 4 gene (Asp299Gly) polymorphism associates with carotid artery elasticity. The cardiovascular risk in young Finns study
    Jussi A Hernesniemi
    Department of Clinical Chemistry, University of Tampere and Tampere University Hospital, Finland
    Atherosclerosis 198:152-9. 2008
  9. ncbi request reprint Interleukin-18 promoter polymorphism associates with the occurrence of sudden cardiac death among Caucasian males: the Helsinki Sudden Death Study
    Jussi A Hernesniemi
    Laboratory of Atherosclerosis Genetics, Tampere University Hospital and Department of Clinical Chemistry, Medical School, University of Tampere, Tampere, Finland
    Atherosclerosis 196:643-9. 2008
  10. doi request reprint Genome-wide association study pinpoints a new functional apolipoprotein B variant influencing oxidized low-density lipoprotein levels but not cardiovascular events: AtheroRemo Consortium
    Kari Matti Mäkelä
    Department of Clinical Chemistry, Finn Medi 2, PO Box 2000, FI 33521 Tampere, Finland
    Circ Cardiovasc Genet 6:73-81. 2013

Collaborators

Detail Information

Publications14

  1. doi request reprint Predicting sudden cardiac death using common genetic risk variants for coronary artery disease
    Jussi A Hernesniemi
    Department of Clinical Chemistry, University of Tampere, Tampere University Hospital and Fimlab Laboratories, Tampere, Finland North Karelia Central Hospital, Tikkamäentie 16, Joensuu 80210, Finland
    Eur Heart J 36:1669-75. 2015
    ..Genome-wide association studies (GWAS) have identified many variants associating with an increased risk of coronary artery disease (CAD). We studied the possible association between these variants and the risk of sudden cardiac death (SCD)...
  2. doi request reprint The prevalence of abdominal aortic aneurysm is consistently high among patients with coronary artery disease
    Jussi A Hernesniemi
    Departments of Internal Medicine and Surgery, North Karelia Central Hospital, Joensuu, Finland Electronic address
    J Vasc Surg 62:232-240.e3. 2015
    ....
  3. pmc Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta
    Jussi A Hernesniemi
    Department of Clinical Chemistry, University of Tampere, Medical School, and Tampere University Hospital, Tampere, Finland
    PLoS ONE 7:e28931. 2012
    ..We examined whether the genetic profiling of these variants improves prediction of subclinical atherosclerosis--i.e., carotid intima-media thickness (CIMT) and carotid artery elasticity (CAE)--beyond classical risk factors...
  4. ncbi request reprint Toll-like receptor 4 polymorphism is associated with coronary stenosis but not with the occurrence of acute or old myocardial infarctions
    J Hernesniemi
    Laboratory of Atherosclerosis Genetics, Department of Clinical Chemistry, Tampere University Hospital and the Medical School at the University of Tampere, Finland
    Scand J Clin Lab Invest 66:667-75. 2006
    ..TLR-4 is activated by, for example, lipopolysaccharides. The purpose of this study was to investigate the role of a common Asp299Gly polymorphism of the TLR-4 gene in atherosclerosis...
  5. doi request reprint Interleukin 18 gene promoter polymorphism: a link between hypertension and pre-hospital sudden cardiac death: the Helsinki Sudden Death Study
    Jussi A Hernesniemi
    Laboratory of Atherosclerosis Genetics, Department of Clinical Chemistry, Tampere University Hospital, Centre for Laboratory Medicine, University of Tampere, Medical School, Finn Medi 2, FI 33521 Tampere, Finland
    Eur Heart J 30:2939-46. 2009
    ..We examined the process by which this polymorphism alters the risk of SCD and coronary artery disease (CAD) by analysing the interactions between this polymorphism and environmental factors...
  6. doi request reprint Interleukin-18 gene polymorphism and markers of subclinical atherosclerosis. The Cardiovascular Risk in Young Finns Study
    Jussi A Hernesniemi
    Department of Clinical Chemistry, University of Tampere and Tampere University Hospital, Finland
    Ann Med 42:223-30. 2010
    ....
  7. doi request reprint IL-18 gene polymorphism, cardiovascular mortality and coronary artery disease
    Jussi A Hernesniemi
    Laboratory of Atherosclerosis Genetics, Department of Clinical Chemistry, Tampere University Hospital, Centre for Laboratory Medicine, Tampere, Finland Medical School, University of Tampere, Tampere, Finland
    Eur J Clin Invest 40:994-1001. 2010
    ....
  8. ncbi request reprint Toll-like receptor 4 gene (Asp299Gly) polymorphism associates with carotid artery elasticity. The cardiovascular risk in young Finns study
    Jussi A Hernesniemi
    Department of Clinical Chemistry, University of Tampere and Tampere University Hospital, Finland
    Atherosclerosis 198:152-9. 2008
    ..We wanted to examine the association of this polymorphism with carotid IMT and compliance in a population of young Finnish Caucasian adults...
  9. ncbi request reprint Interleukin-18 promoter polymorphism associates with the occurrence of sudden cardiac death among Caucasian males: the Helsinki Sudden Death Study
    Jussi A Hernesniemi
    Laboratory of Atherosclerosis Genetics, Tampere University Hospital and Department of Clinical Chemistry, Medical School, University of Tampere, Tampere, Finland
    Atherosclerosis 196:643-9. 2008
    ..The C allele carriage is associated with attenuated IL-18 production. The effect of IL-18 genotype on SCD is unknown. We studied the association of the IL-18 gene -137G/C polymorphism with the occurrence of sudden cardiac death (SCD)...
  10. doi request reprint Genome-wide association study pinpoints a new functional apolipoprotein B variant influencing oxidized low-density lipoprotein levels but not cardiovascular events: AtheroRemo Consortium
    Kari Matti Mäkelä
    Department of Clinical Chemistry, Finn Medi 2, PO Box 2000, FI 33521 Tampere, Finland
    Circ Cardiovasc Genet 6:73-81. 2013
    ..We performed a genome-wide association study on oxidized low-density lipoprotein and tested the impact of associated single-nucleotide polymorphisms (SNPs) on the risk factors of atherosclerosis and cardiovascular events...
  11. doi request reprint Association of the novel single-nucleotide polymorphism which increases oxidized low-density lipoprotein levels with cerebrovascular disease events
    Kari Matti Mäkelä
    School of Medicine, University of Tampere, Tampere, Finland Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland Electronic address
    Atherosclerosis 234:214-7. 2014
    ..Patients with genetic background for high circulating oxidized low-density lipoprotein (oxLDL) levels might be at an increased risk of cerebrovascular disease (CVD)...
  12. doi request reprint Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality
    Ilkka Seppälä
    Department of Clinical Chemistry, Fimlab Laboratories, Tampere University School of Medicine, Finn Medi 2, 3rd Floor, PO Box 2000, Tampere FI 33521, Finland
    Eur Heart J 35:524-31. 2014
    ....
  13. doi request reprint ADAM8 and its single nucleotide polymorphism 2662 T/G are associated with advanced atherosclerosis and fatal myocardial infarction: Tampere vascular study
    Mari Levula
    Laboratory of Atherosclerosis Genetics, Centre for Laboratory Medicine, Tampere University Hospital and Department of Clinical Chemistry, Medical School, University of Tampere, Finland
    Ann Med 41:497-507. 2009
    ..Previously, we scanned all 23,000 human genes for differential expression between normal and atherosclerotic tissues and found the involvement of ADAM8...
  14. doi request reprint Significant interactions between traditional risk factors affect cardiovascular risk prediction in healthy general population
    Jussi A Hernesniemi
    North Karelia Central Hospital, Joensuu, Finland
    Ann Med 47:53-60. 2015
    ..The aim was to carry out a systematic screening of interactions between the traditional risk factors and to evaluate which interactions are truly relevant for estimation of cardiovascular disease (CVD) risk...