Ilkka Helantera

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. ncbi request reprint The impact of cytomegalovirus infections and acute rejection episodes on the development of vascular changes in 6-month protocol biopsy specimens of cadaveric kidney allograft recipients
    Ilkka Helantera
    Department of Virology, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland
    Transplantation 75:1858-64. 2003
  2. doi request reprint BK virus viremia in a well-HLA-matched kidney transplant population mainly on low-dose cyclosporine-based immunosuppression
    Ilkka Helantera
    Division of Nephrology, Department of Medicine, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
    Clin Transplant 26:E596-601. 2012
  3. doi request reprint Employment of patients receiving maintenance dialysis and after kidney transplant: a cross-sectional study from Finland
    Ilkka Helantera
    Deparment of Medicine, Division of Nephrology, Helsinki University Central Hospital, Helsinki, Finland
    Am J Kidney Dis 59:700-6. 2012
  4. doi request reprint The risk of cytomegalovirus recurrence after kidney transplantation
    Ilkka Helantera
    Division of Nephrology, Department of Medicine, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland
    Transpl Int 24:1170-8. 2011
  5. doi request reprint Primary CMV infections are common in kidney transplant recipients after 6 months valganciclovir prophylaxis
    I Helantera
    Department of Medicine, Division of Nephrology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
    Am J Transplant 10:2026-32. 2010
  6. doi request reprint Impact of glucose metabolism abnormalities on histopathological changes in kidney transplant protocol biopsies
    Ilkka Helantera
    Department of Medicine, Division of Nephrology, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland
    Transpl Int 23:374-81. 2010
  7. doi request reprint Polyomavirus BK and JC infections in well matched Finnish kidney transplant recipients
    Ilkka Helantera
    Department of Medicine, Division of Nephrology, Helsinki University Central Hospital and University of Helsinki, FIN 00029 HUS, Helsinki, Finland
    Transpl Int 22:688-93. 2009
  8. doi request reprint Prospective follow-up of primary CMV infections after 6 months of valganciclovir prophylaxis in renal transplant recipients
    Ilkka Helantera
    Department of Medicine, Division of Nephrology, Helsinki University Hospital, Helsinki, Finland
    Nephrol Dial Transplant 24:316-20. 2009
  9. doi request reprint Demonstration of HHV-6 antigens in biopsies of kidney transplant recipients with cytomegalovirus infection
    Ilkka Helantera
    Transplant Unit Research Laboratory, Department of Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
    Transpl Int 21:980-4. 2008
  10. ncbi request reprint Timing and value of protocol biopsies in well-matched kidney transplant recipients--a clinical and histopathologic analysis
    Ilkka Helantera
    Department of Medicine, Division of Nephrology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland
    Transpl Int 20:982-90. 2007

Detail Information

Publications14

  1. ncbi request reprint The impact of cytomegalovirus infections and acute rejection episodes on the development of vascular changes in 6-month protocol biopsy specimens of cadaveric kidney allograft recipients
    Ilkka Helantera
    Department of Virology, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland
    Transplantation 75:1858-64. 2003
    ..The purpose of this study was to examine the impact of CMV infection on histopathologic changes in 6-month protocol biopsy specimens of kidney allografts...
  2. doi request reprint BK virus viremia in a well-HLA-matched kidney transplant population mainly on low-dose cyclosporine-based immunosuppression
    Ilkka Helantera
    Division of Nephrology, Department of Medicine, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
    Clin Transplant 26:E596-601. 2012
    ..No grafts were lost due to PyVAN. Even in a low-risk population, BKV viremia and PyVAN occur, highlighting the importance of monitoring viral loads. Reduction of immunosuppression was successful, and no grafts were lost due to PyVAN...
  3. doi request reprint Employment of patients receiving maintenance dialysis and after kidney transplant: a cross-sectional study from Finland
    Ilkka Helantera
    Deparment of Medicine, Division of Nephrology, Helsinki University Central Hospital, Helsinki, Finland
    Am J Kidney Dis 59:700-6. 2012
    ..Associations between mode of renal replacement therapy and employment rate have not been well characterized...
  4. doi request reprint The risk of cytomegalovirus recurrence after kidney transplantation
    Ilkka Helantera
    Division of Nephrology, Department of Medicine, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland
    Transpl Int 24:1170-8. 2011
    ..CMV recurrences occur commonly despite secondary prophylaxis. High viral load at diagnosis predicted the risk of recurrent CMV infection...
  5. doi request reprint Primary CMV infections are common in kidney transplant recipients after 6 months valganciclovir prophylaxis
    I Helantera
    Department of Medicine, Division of Nephrology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
    Am J Transplant 10:2026-32. 2010
    ..Recurrent CMV infection developed in 9/47 (19%) patients. No significant risk factors for CMV infection were identified. Symptomatic primary CMV infections were commonly detected also after prolonged valganciclovir prophylaxis...
  6. doi request reprint Impact of glucose metabolism abnormalities on histopathological changes in kidney transplant protocol biopsies
    Ilkka Helantera
    Department of Medicine, Division of Nephrology, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland
    Transpl Int 23:374-81. 2010
    ..01). Glucose abnormalities were associated with the progression of histopathological changes, especially in patients with already compromised kidneys, supporting the harmful role of PTDM to the kidney allograft...
  7. doi request reprint Polyomavirus BK and JC infections in well matched Finnish kidney transplant recipients
    Ilkka Helantera
    Department of Medicine, Division of Nephrology, Helsinki University Central Hospital and University of Helsinki, FIN 00029 HUS, Helsinki, Finland
    Transpl Int 22:688-93. 2009
    ..The incidence of BK and JC viruria was similar to what has been previously reported, but no cases of polyomavirus-associated nephropathy were seen in our well-matched kidney transplant population...
  8. doi request reprint Prospective follow-up of primary CMV infections after 6 months of valganciclovir prophylaxis in renal transplant recipients
    Ilkka Helantera
    Department of Medicine, Division of Nephrology, Helsinki University Hospital, Helsinki, Finland
    Nephrol Dial Transplant 24:316-20. 2009
    ..The occurrence and clinical course of late primary CMV infections developing after valganciclovir prophylaxis in high-risk renal transplant recipients are poorly described...
  9. doi request reprint Demonstration of HHV-6 antigens in biopsies of kidney transplant recipients with cytomegalovirus infection
    Ilkka Helantera
    Transplant Unit Research Laboratory, Department of Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
    Transpl Int 21:980-4. 2008
    ..In conclusion, HHV-6 was a common finding in late renal allograft biopsies of patients with previous CMV infection, but its significance remains to be elucidated...
  10. ncbi request reprint Timing and value of protocol biopsies in well-matched kidney transplant recipients--a clinical and histopathologic analysis
    Ilkka Helantera
    Department of Medicine, Division of Nephrology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland
    Transpl Int 20:982-90. 2007
    ..In our well-matched population, the predictive value of a biopsy at 3 months was inferior to biopsies at 6 or 12 months, both of which were effective in predicting long-term graft function...
  11. ncbi request reprint Persistent cytomegalovirus infection in kidney allografts is associated with inferior graft function and survival
    Ilkka Helantera
    Department of Medicine, Division of Nephrology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
    Transpl Int 19:893-900. 2006
    ..4 and 4.9). Our novel findings show that persistent intragraft CMV infection was associated with reduced kidney allograft function and survival...
  12. ncbi request reprint Increased urinary excretion of transforming growth factor-beta(1) in renal transplant recipients during cytomegalovirus infection
    Ilkka Helantera
    Department of Virology, Helsinki University Central Hospital and University of Helsinki, Meilahti, FIN 00029 HUS, Helsinki, Finland
    Transpl Immunol 15:217-21. 2006
    ..CMV has been shown to induce the expression of TGF-beta and several cytokines. We analyzed the impact of CMV on urinary excretion of TGF-beta, ICAM-1, TNF-alpha and correlated findings with biopsy histology...
  13. ncbi request reprint Persistent cytomegalovirus infection is associated with increased expression of TGF-beta1, PDGF-AA and ICAM-1 and arterial intimal thickening in kidney allografts
    Ilkka Helantera
    Department of Virology, Helsinki University Hospital and Univeristy of Helsinki, Finland
    Nephrol Dial Transplant 20:790-6. 2005
    ..We analysed the impact of persistent CMV infection in kidney allografts on the expression of growth factors, adhesion molecules and inflammation markers...
  14. doi request reprint Viral impact on long-term kidney graft function
    Ilkka Helantera
    Transplant Unit Research Laboratory, Transplantation and Liver Surgery Clinic, Helsinki University Hospital, and University of Helsinki, Meilahti, PL 340, Helsinki, FI 00029 HUS, Finland
    Infect Dis Clin North Am 24:339-71. 2010
    ..An update on the pathophysiology of smoldering viral replication, associated inflammatory damage, and the presumed indirect viral effects is provided, and the implications for diagnostic tests and antiviral intervention are discussed...