Timo Hautala

Summary

Affiliation: University of Oulu
Country: Finland

Publications

  1. pmc Elevated cerebrospinal fluid neopterin concentration is associated with disease severity in acute Puumala hantavirus infection
    Timo Hautala
    Department of Internal Medicine, Oulu University Hospital, P O Box 20, 90029 Oulu, Finland
    Clin Dev Immunol 2013:634632. 2013
  2. doi request reprint Signs of general inflammation and kidney function are associated with the ocular features of acute Puumala hantavirus infection
    Nina Hautala
    Department of Ophthalmology, Oulu University Hospital, Oulu, Finland
    Scand J Infect Dis 44:956-62. 2012
  3. pmc Endostatin inhibits VEGF-A induced osteoclastic bone resorption in vitro
    Annina Sipola
    Dept of Anatomy and Cell Biology, PO Box 5000, FIN 90014 University of Oulu, Finland
    BMC Musculoskelet Disord 7:56. 2006
  4. pmc Young male patients are at elevated risk of developing serious central nervous system complications during acute Puumala hantavirus infection
    Timo Hautala
    Department of Internal Medicine, Oulu University Hospital, Oulu, Finland
    BMC Infect Dis 11:217. 2011
  5. doi request reprint Clinical Candida krusei isolates remain susceptible during extensive exposure to antifungal drugs
    Timo Hautala
    Department of Internal Medicine, Oulu University Hospital, Oulu, Finland
    Med Mycol 48:79-84. 2010
  6. pmc A cluster of Candida krusei infections in a haematological unit
    Timo Hautala
    Department of Internal Medicine, Oulu University Hospital, Oulu, Finland
    BMC Infect Dis 7:97. 2007
  7. ncbi request reprint [Use of antibiotics in hospital--to guide or to limit]
    Timo Hautala
    sisãtautien klinikka, Oulun yliopisto
    Duodecim 121:1683-8. 2005
  8. ncbi request reprint Blood culture Gram stain and clinical categorization based empirical antimicrobial therapy of bloodstream infection
    Timo Hautala
    Department of Internal Medicine, Oulu University Hospital, P O Box 5000, FIN 90014 Oulu, Finland
    Int J Antimicrob Agents 25:329-33. 2005
  9. doi request reprint Central nervous system-related symptoms and findings are common in acute Puumala hantavirus infection
    Timo Hautala
    Department of Internal Medicine, Oulu University Hospital, Oulu, Finland
    Ann Med 42:344-51. 2010
  10. doi request reprint Prospective study on ocular findings in acute Puumala hantavirus infection in hospitalised patients
    Nina Hautala
    Department of Ophthalmology, Oulu University Hospital, FIN 90029 OYS, Finland
    Br J Ophthalmol 95:559-62. 2011

Collaborators

Detail Information

Publications15

  1. pmc Elevated cerebrospinal fluid neopterin concentration is associated with disease severity in acute Puumala hantavirus infection
    Timo Hautala
    Department of Internal Medicine, Oulu University Hospital, P O Box 20, 90029 Oulu, Finland
    Clin Dev Immunol 2013:634632. 2013
    ..These results reinforce the view that PUUV-HFRS is a general infection that affects the central nervous system and the blood-brain barrier...
  2. doi request reprint Signs of general inflammation and kidney function are associated with the ocular features of acute Puumala hantavirus infection
    Nina Hautala
    Department of Ophthalmology, Oulu University Hospital, Oulu, Finland
    Scand J Infect Dis 44:956-62. 2012
    ..Acute illness is associated with increased tissue permeability and tissue oedema, and many patients experience reduced vision. The aim of this study was to explore the physiological events associated with the ocular features of acute NE...
  3. pmc Endostatin inhibits VEGF-A induced osteoclastic bone resorption in vitro
    Annina Sipola
    Dept of Anatomy and Cell Biology, PO Box 5000, FIN 90014 University of Oulu, Finland
    BMC Musculoskelet Disord 7:56. 2006
    ..Our study aims at exploring a possibility that endostatin, either as a part of basement membrane or as a soluble molecule, may control osteoclastogenesis and osteoclastic bone resorption in vitro...
  4. pmc Young male patients are at elevated risk of developing serious central nervous system complications during acute Puumala hantavirus infection
    Timo Hautala
    Department of Internal Medicine, Oulu University Hospital, Oulu, Finland
    BMC Infect Dis 11:217. 2011
    ....
  5. doi request reprint Clinical Candida krusei isolates remain susceptible during extensive exposure to antifungal drugs
    Timo Hautala
    Department of Internal Medicine, Oulu University Hospital, Oulu, Finland
    Med Mycol 48:79-84. 2010
    ..We conclude that resistance development in Candida krusei during prolonged antifungal treatment may not be common and the treatment failure of our patients was not likely due to the development of drug resistance by the etiologic agent...
  6. pmc A cluster of Candida krusei infections in a haematological unit
    Timo Hautala
    Department of Internal Medicine, Oulu University Hospital, Oulu, Finland
    BMC Infect Dis 7:97. 2007
    ..In order to explore ways to prevent these infections, we investigated potential routes for nosocomial spread and possible clonality of C. krusei in a haematological unit which had experienced an unusually high incidence of cases...
  7. ncbi request reprint [Use of antibiotics in hospital--to guide or to limit]
    Timo Hautala
    sisãtautien klinikka, Oulun yliopisto
    Duodecim 121:1683-8. 2005
  8. ncbi request reprint Blood culture Gram stain and clinical categorization based empirical antimicrobial therapy of bloodstream infection
    Timo Hautala
    Department of Internal Medicine, Oulu University Hospital, P O Box 5000, FIN 90014 Oulu, Finland
    Int J Antimicrob Agents 25:329-33. 2005
    ..We conclude that Gram stain results of positive blood cultures along with the knowledge of where the infection was acquired, would allow early accurate targeting of antimicrobial therapy for BSI...
  9. doi request reprint Central nervous system-related symptoms and findings are common in acute Puumala hantavirus infection
    Timo Hautala
    Department of Internal Medicine, Oulu University Hospital, Oulu, Finland
    Ann Med 42:344-51. 2010
    ..Recent case reports and retrospective studies suggest that NE may damage the pituitary gland. Based on these observations, our goal was to explore the nature of this complication prospectively...
  10. doi request reprint Prospective study on ocular findings in acute Puumala hantavirus infection in hospitalised patients
    Nina Hautala
    Department of Ophthalmology, Oulu University Hospital, FIN 90029 OYS, Finland
    Br J Ophthalmol 95:559-62. 2011
    ..To appraise the ocular manifestations of Puumala hantavirus evoked haemorrhagic fever with renal syndrome nephropathia epidemica (NE) and to clarify the mechanisms of ocular changes in the largest series of patients examined to date...
  11. ncbi request reprint Puumala virus RNA in cerebrospinal fluid in a patient with uncomplicated nephropathia epidemica
    Saara Mari Mähönen
    Department of Medical Microbiology, University of Oulu, Oulu, Finland
    J Clin Virol 40:248-51. 2007
  12. ncbi request reprint Hypophyseal hemorrhage and panhypopituitarism during Puumala Virus Infection: Magnetic Resonance Imaging and detection of viral antigen in the hypophysis
    Timo Hautala
    Department of Internal Medicine, University of Oulu, Oulu, FIN 90014 Oulu, Finland
    Clin Infect Dis 35:96-101. 2002
    ....
  13. doi request reprint Plasma B-type natriuretic peptide (BNP) in acute Puumala hantavirus infection
    Saara Mari Rajaniemi
    Institute of Diagnostics, Department of Medical Microbiology, University of Oulu, Oulu, Finland
    Ann Med 46:38-43. 2014
    ..Nephropathia epidemica (NE) is a haemorrhagic fever with renal syndrome (HFRS) caused by Puumala hantavirus (PUUV). Acute infection causes transient kidney injury, permeability disorder, and fluid retention, for example...
  14. ncbi request reprint Major age group-specific differences in conjunctival bacteria and evolution of antimicrobial resistance revealed by laboratory data surveillance
    Nina Hautala
    Department of Ophthalmology, Oulu University Hospital, Oulu, Finland
    Curr Eye Res 33:907-11. 2008
    ..We further assumed that the statistical data should expose evolution of antimicrobial resistance that may eventually have an influence on clinical decisions...
  15. ncbi request reprint Adenoviral VEGF-A gene transfer induces angiogenesis and promotes bone formation in healing osseous tissues
    Tatu Tarkka
    Department of Surgery, University of Tampere, Finland
    J Gene Med 5:560-6. 2003
    ..VEGF has an important role in bone repair by promoting angiogenesis and by stimulating major skeletal cell populations, chondrocytes, osteoblasts and osteoclasts...