Jari Haukka

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..The consumption of statins (HMG-CoA reductase inhibitors) in most Western countries has increased to the extent that it may affect all-cause and disease-specific mortality...

..We also analyzed the emergence of psychotic disorders among siblings of patients with schizophrenia during seven to eleven years of follow-up...

..20, P < .0001). Lighting conditions and their dynamics may serve as a measure for intervention in order to influence the seasonal metabolic signals and in the end to prevent the metabolic syndrome...

..We investigated the degree to which hopelessness is trait- or state-related during the course of BD...

..The aim of the study was to examine the association between social background and drunken driving...

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..Therefore, the importance of state factors, particularly time spent in risk states, for overall risk remains unknown...

..57, 2.21) and mood disorders (SHR = 1.72, 95% CI: 1.47, 2.01) were associated with the risk of suicide. The risks of suicide and all-cause mortality were extremely high immediately after hospitalization for attempted suicide...

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..It is generally acknowledged that depressed patients need specific attention during the first weeks after initiation of antidepressant (AD) treatment because of the increased risk of suicide...

..Here, we evaluated whether such deficits might also mark genetic susceptibility to bipolar disorder...

..We examined the geographical variation in the lifetime prevalence of psychotic disorders in a comprehensive general population study...

..The authors compared verbal learning and memory functioning in twins with BP I and co-twins to control twins, and examined whether the observed deficits are related to information-processing speed...

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..We examined the length and continuity of antidepressant treatment and factors associated with long-term of treatment among adults...

..We found neither beneficial nor harmful associations between the usage of statins and cancer...

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..As conclusion, no clear evidence of neither beneficial nor harmful association between usage of antidepressant and cancer was found...

..Our results also point to a potential birth-weight independent association between maternal type 2 diabetes and schizophrenia among offspring...

..Genetic contribution was low to verbal learning functions. High heritability, in executive functioning and psychomotor processing speed suggest that these may be valid endophenotypic traits for genetic studies of bipolar disorder...

..This may be related to genetic homogeneity in the isolate. We conclude that patients with first-degree relatives with psychotic disorder have more severe negative symptoms...

..This study examined the association between the dietary intake of omega-3 fatty acids and low mood, major depression, and suicide...

..Differences in the incidence of suicide attempts during various phases of bipolar disorder (BD), or the relative importance of static versus time-varying risk factors for overall risk for suicide attempts, are unknown...

..The same risk alleles resulted in clinically significant differences in outcome of patients with major depressive and bipolar disorder...

..We compared the point prevalence of psychotropic medication use, and self-reported vs. register-based information on antipsychotic medication dosage...

..Our aim was to study whether circadian clock gene polymorphisms predispose to alcohol dependence or abuse or other alcohol-related characteristics...

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..Disturbances in sleep patterns are common and may compromise wellbeing even in the short term. Our hypothesis was that simulated dawn could improve the subjective quality of sleep during winter...

..This is the first study in the treatment of depression in dual diagnosis patients to report a significant association between outcomes with escitalopram and the 5-HTTLPR gene polymorphism...

..Metabolic syndrome is a risk factor to the cardiovascular diseases. It has been reported that disruptions of the circadian clockwork are associated with and may predispose to metabolic syndrome...

..The aim of this study was to explore the effects of transitions into and out of daylight saving time on the incidence of accidents and manic episodes in the Finnish population during the years of 1987 to 2003...

..However, suicide risk declines over time after an attempt, and it is unclear how long the risk persists. Risk estimates are almost exclusively based on studies of less than 10 years of follow-up...

..Our results demonstrated that transitions into and out of daylight saving time did not increase the number of traffic road accidents...

..We explored background variables possibly explaining the individual variation in treatment response or failure in a randomised trial...

..We investigated the mortality of schizophrenia patients in the general population of Finland during the reduction of psychiatric beds during 1980-1996...

..To examine the associations between socio-economic characteristics and driving under the influence of drugs (DUID), and to elaborate determinants of drugged driving...

..The aim of the study was to detect family clusters with similar cognitive test performance...

..The authors investigated whether the siblings of patients with schizophrenia produce more offspring, thereby compensating for the low fertility of the affected individuals...

..The aim of this cohort study was to examine equity in access to coronary care among persons with a history of severe mental disorder in 1998-2009...

..An earlier Finnish cohort study suggested that childhood viral CNS infections are associated with a fivefold increased odds of developing schizophrenia in adulthood. The authors sought to replicate this finding...

..Our findings would also encourage more detailed analyses of the effect of DISC1 on the component-traits of schizophrenia...

..There is no consistent association between dietary intake of amino acids and low mood...

..singleton differences were selective to the backward visual span task, strengthens the view that the visual domain of working memory may provide a valuable endophenotypic marker for genetic schizophrenia studies...

..A higher risk of having any of the pathological conditions was associated with a lower height Z-score. Careful follow-up of cranial base anomalies particularly in subjects with OI and severe growth failure is warranted...

..Nocturia (ie, waking at night to void) is common and disrupts sleep. Traditionally, one nightly episode has been regarded as clinically meaningless, yet the justification for this belief remains weak...

..Because the genetic background of these associations is not thoroughly investigated, we aimed to analyze it in a longitudinal twin cohort...

..A secondary objective was to investigate whether this response differed by season (summer or winter), seasonality, or age...