Research Topics
| Valma HarjutsaloSummaryAffiliation: University of Helsinki Country: Finland Publications
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Detail Information
Publications
Time trends in mortality in patients with type 1 diabetes: nationwide population based cohort studyValma Harjutsalo
Folkhalsan Institute of Genetics, Folkhälsan Research Centre, Biomedicum Helsinki, Haartmaninkatu 8, PO Box 63, FIN 00014, Helsinki, Finland
BMJ 343:d5364. 2011..To examine short and long term time trends in mortality among patients with early onset (age 0-14 years) and late onset (15-29 years) type 1 diabetes and causes of deaths over time...
Age at onset of type 1 diabetes in parents and recurrence risk in offspringValma Harjutsalo
Folkhalsan Institute of Genetics, Folkhälsan Research Centre, Biomedicum Helsinki, Helsinki, Finland
Diabetes 59:210-4. 2010....
Decline in the cumulative incidence of severe diabetic retinopathy in patients with type 1 diabetesJanne P Kytö
Department of Ophthalmology, Helsinki University Central Hospital, Helsinki, Finland
Diabetes Care 34:2005-7. 2011..To determine if the cumulative incidence of severe retinopathy in patients with type 1 diabetes has changed...
Pulse pressure predicts incident cardiovascular disease but not diabetic nephropathy in patients with type 1 diabetes (The FinnDiane Study)Daniel Gordin
Folkhalsan Institute of Genetics, Folkhalsan Research Center, Biomedicum Helsinki, Helsinki, Finland
Diabetes Care 34:886-91. 2011..Furthermore, the role of PP as a predictor of diabetic nephropathy is not known. Therefore, we prospectively investigated the associations between PP and these diabetes complications in patients with T1D...
Menopause in women with type 1 diabetesLena Sjöberg
Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki, Finland
Menopause 18:158-63. 2011..Our objective was to study age at menopause and the factors associated with it in a large population-based group of Finnish women with childhood-onset type 1 diabetes...
Genetic random effects model for family data with long-term survivors: analysis of diabetic nephropathy in type 1 diabetesJanne Pitkäniemi
Department of Public Health, University of Helsinki, Helsinki, Finland
Genet Epidemiol 31:697-708. 2007..According to the variance components estimated a substantial familial variation in the susceptibility to DN exist among families, while time to DN is less influenced by shared familial factors...
Time trends in the incidence of type 1 diabetes in Finnish children: a cohort studyValma Harjutsalo
Diabetes Unit, Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
Lancet 371:1777-82. 2008..Our aim was to assess the temporal trend in type 1 diabetes incidence since 2000 in Finnish children aged younger than 15 years and to predict the number of cases of type 1 diabetes in the future...
Age at onset and the risk of proliferative retinopathy in type 1 diabetesKustaa Hietala
Folkhalsan Institute of Genetics, Folkhalsan Research Center, Biomedicum Helsinki, Helsinki, Finland
Diabetes Care 33:1315-9. 2010..Age at onset of type 1 diabetes influences the risk of microvascular complications. However, the long-term risk of proliferative retinopathy within the wide spectrum of age at onset of type 1 diabetes is less well known...
Competing-risk analysis of ESRD and death among patients with type 1 diabetes and macroalbuminuriaCarol Forsblom
Folkhalsan Research Center, Biomedicum Helsinki, Haartmaninkatu 8, University of Helsinki, Finland
J Am Soc Nephrol 22:537-44. 2011..This competing-risks approach has potential to highlight the appropriate targets and strategies for preventing premature mortality in patients with type 1 diabetes...
Cumulative incidence of type 1 diabetes in 10,168 siblings of Finnish young-onset type 1 diabetic patientsValma Harjutsalo
Diabetes and Genetic Epidemiology Unit, Department of Epidemiology and Health Promotion, National Public Health Institute, Mannerheimintie 166, FIN 00300, Helsinki, Finland
Diabetes 54:563-9. 2005..This large prospective family study of type 1 diabetes in siblings of childhood-onset diabetic patients provides reliable empirical estimates for the sibling recurrence risk...
Longitudinal trends in use and costs of prescription medication in patients with type 1 diabetes: the impact of renal diseaseRaija Lithovius
Folkhalsan Institute of Genetics, Folkhalsan Research Center, Biomedicum Helsinki, Finland
Ann Med 45:112-9. 2013..We estimated trends in prescription medication costs in out-patients with type 1 diabetes by various stages of diabetic nephropathy (DN), before the development of end-stage renal disease, between 1995 and 2005...
New susceptibility loci associated with kidney disease in type 1 diabetesNiina Sandholm
Folkhalsan Institute of Genetics, Folkhalsan Research Center, Biomedicum Helsinki, Helsinki, Finland
PLoS Genet 8:e1002921. 2012..1 × 10(-7)), a gene with type 2 diabetes DN differential expression and in the same intron as a variant with cis-eQTL expression of ERBB4. All these detected associations represent new signals in the pathogenesis of DN...
Genetic and environmental effects on fasting and postchallenge plasma glucose and serum insulin values in Finnish twinsShuichi Katoh
Diabetes and Genetic Epidemiology Unit, National Public Health Institute, Helsinki, Finland
J Clin Endocrinol Metab 90:2642-7. 2005..81). In conclusion, additive genetic effects are important for the insulin secretion, whereas nonshared environmental effects contribute strongly to peripheral insulin resistance...
