Steffi Goffart

Summary

Affiliation: University of Tampere
Country: Finland

Publications

  1. ncbi request reprint Alpha-actinin 4 and BAT1 interaction with the cytochrome c promoter upon skeletal muscle differentiation
    Steffi Goffart
    Institute of Vegetative Physiology, Medical Faculty, University of Koln, Germany
    Curr Genet 49:125-35. 2006
  2. pmc Developmental and pathological changes in the human cardiac muscle mitochondrial DNA organization, replication and copy number
    Jaakko L O Pohjoismäki
    Department of Forensic Medicine, Medical School, University of Tampere, Tampere, Finland
    PLoS ONE 5:e10426. 2010
  3. pmc CREB-1alpha is recruited to and mediates upregulation of the cytochrome c promoter during enhanced mitochondrial biogenesis accompanying skeletal muscle differentiation
    Andras Franko
    Institute of Vegetative Physiology, Medical Faculty, University of Koln, Robert Koch Strasse 39, 50931 Koln, Germany
    Mol Cell Biol 28:2446-59. 2008
  4. ncbi request reprint Regulation of mitochondrial proliferation in the heart: power-plant failure contributes to cardiac failure in hypertrophy
    Steffi Goffart
    Institute of Vegetative Physiology, University of Koln, Robert Koch Str 39, 50931 Koln, Germany
    Cardiovasc Res 64:198-207. 2004
  5. pmc Transient overexpression of mitochondrial transcription factor A (TFAM) is sufficient to stimulate mitochondrial DNA transcription, but not sufficient to increase mtDNA copy number in cultured cells
    Katharina Maniura-Weber
    Institute of Vegetative Physiology, Medical Faculty, University of Koln, Robert Koch Strasse 39, D 50931 Köln, FRG
    Nucleic Acids Res 32:6015-27. 2004

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Alpha-actinin 4 and BAT1 interaction with the cytochrome c promoter upon skeletal muscle differentiation
    Steffi Goffart
    Institute of Vegetative Physiology, Medical Faculty, University of Koln, Germany
    Curr Genet 49:125-35. 2006
    ..In conclusion, the analyzed sequence motif may be a new candidate for common regulatory elements specific for nuclear encoded mitochondrial genes, and alpha-actinin 4 may be involved in their regulation...
  2. pmc Developmental and pathological changes in the human cardiac muscle mitochondrial DNA organization, replication and copy number
    Jaakko L O Pohjoismäki
    Department of Forensic Medicine, Medical School, University of Tampere, Tampere, Finland
    PLoS ONE 5:e10426. 2010
    ..Additionally, we show that Twinkle might have a direct role in the maintenance of four-way junctions in human heart mtDNA...
  3. pmc CREB-1alpha is recruited to and mediates upregulation of the cytochrome c promoter during enhanced mitochondrial biogenesis accompanying skeletal muscle differentiation
    Andras Franko
    Institute of Vegetative Physiology, Medical Faculty, University of Koln, Robert Koch Strasse 39, 50931 Koln, Germany
    Mol Cell Biol 28:2446-59. 2008
    ....
  4. ncbi request reprint Regulation of mitochondrial proliferation in the heart: power-plant failure contributes to cardiac failure in hypertrophy
    Steffi Goffart
    Institute of Vegetative Physiology, University of Koln, Robert Koch Str 39, 50931 Koln, Germany
    Cardiovasc Res 64:198-207. 2004
    ....
  5. pmc Transient overexpression of mitochondrial transcription factor A (TFAM) is sufficient to stimulate mitochondrial DNA transcription, but not sufficient to increase mtDNA copy number in cultured cells
    Katharina Maniura-Weber
    Institute of Vegetative Physiology, Medical Faculty, University of Koln, Robert Koch Strasse 39, D 50931 Köln, FRG
    Nucleic Acids Res 32:6015-27. 2004
    ..Thus, this protein meets all criteria for being a key factor regulating mitochondrial transcription in vivo, but other factors are necessary for increasing mtDNA copy number, at least in cultured cells...