Gabriela D'Amico

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. pmc Regulation of lymphatic-blood vessel separation by endothelial Rac1
    Gabriela D'Amico
    Adhesion and Angiogenesis Laboratory, Institute of Cancer and Cancer Research UK, Bart s and the London Queen Mary s School of Medicine and Dentistry, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK
    Development 136:4043-53. 2009
  2. pmc Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent
    Gabriela D'Amico
    Adhesion and Angiogenesis Laboratory, Institute of Cancer, Bart s and The London, Queen Mary s School of Medicine and Dentistry, London, United Kingdom
    PLoS ONE 5:e9766. 2010
  3. pmc Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome
    Louise E Reynolds
    Adhesion and Angiogenesis Laboratory, Barts Institute of Cancer, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK
    Nature 465:813-7. 2010
  4. doi Genetic ablation of the alpha 6-integrin subunit in Tie1Cre mice enhances tumour angiogenesis
    Mitchel Germain
    The Adhesion and Angiogenesis Laboratory, Institute of Cancer, Queen Mary, University of London, Charterhouse Square, London, EC1M 6BQ, UK
    J Pathol 220:370-81. 2010
  5. doi Use of the mouse aortic ring assay to study angiogenesis
    Marianne Baker
    Adhesion and Angiogenesis Laboratory, Centre for Tumour Biology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, UK
    Nat Protoc 7:89-104. 2012
  6. doi Integrins: the keys to unlocking angiogenesis
    Rita Silva
    Adhesion and Angiogenesis Group, Centre for Tumour Biology, Cancer Research UK Clinical Centre, Institute of Cancer, Barts and The London and Queen Mary s School of Medicine and Dentistry, John Vane Science Centre, Charterhouse Square, London UK
    Arterioscler Thromb Vasc Biol 28:1703-13. 2008

Collaborators

Detail Information

Publications6

  1. pmc Regulation of lymphatic-blood vessel separation by endothelial Rac1
    Gabriela D'Amico
    Adhesion and Angiogenesis Laboratory, Institute of Cancer and Cancer Research UK, Bart s and the London Queen Mary s School of Medicine and Dentistry, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK
    Development 136:4043-53. 2009
    ..Our studies identify Rac1 as a crucial part of the migratory machinery required for endothelial cells to separate and form lymphatic vasculature...
  2. pmc Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent
    Gabriela D'Amico
    Adhesion and Angiogenesis Laboratory, Institute of Cancer, Bart s and The London, Queen Mary s School of Medicine and Dentistry, London, United Kingdom
    PLoS ONE 5:e9766. 2010
    ..These data indicate that in the presence of alphavbeta3-integrin Rac1 is not required for tumor angiogenesis...
  3. pmc Tumour angiogenesis is reduced in the Tc1 mouse model of Down's syndrome
    Louise E Reynolds
    Adhesion and Angiogenesis Laboratory, Barts Institute of Cancer, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London EC1M 6BQ, UK
    Nature 465:813-7. 2010
    ....
  4. doi Genetic ablation of the alpha 6-integrin subunit in Tie1Cre mice enhances tumour angiogenesis
    Mitchel Germain
    The Adhesion and Angiogenesis Laboratory, Institute of Cancer, Queen Mary, University of London, Charterhouse Square, London, EC1M 6BQ, UK
    J Pathol 220:370-81. 2010
    ..By developing the first endothelial-specific alpha6-knockout mice, we show that the expression of the alpha6-integrin subunit in endothelial cells acts as a negative regulator of angiogenesis both in vivo and ex vivo...
  5. doi Use of the mouse aortic ring assay to study angiogenesis
    Marianne Baker
    Adhesion and Angiogenesis Laboratory, Centre for Tumour Biology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, UK
    Nat Protoc 7:89-104. 2012
    ..The assay takes 6-14 d to complete, depending on the age of the mice, treatments applied and whether immunostaining is performed...
  6. doi Integrins: the keys to unlocking angiogenesis
    Rita Silva
    Adhesion and Angiogenesis Group, Centre for Tumour Biology, Cancer Research UK Clinical Centre, Institute of Cancer, Barts and The London and Queen Mary s School of Medicine and Dentistry, John Vane Science Centre, Charterhouse Square, London UK
    Arterioscler Thromb Vasc Biol 28:1703-13. 2008
    ..Here we review the contribution of endothelial and mural cell integrins to angiogenesis and highlight their potential as antiangiogenesis targets...