Maija Castrén

Summary

Affiliation: University of Helsinki
Country: Finland

Publications

  1. ncbi request reprint BDNF in fragile X syndrome
    Maija L Castrén
    Institute of Biomedicine Physiology, University of Helsinki, P O Box 63, FIN 00014 Helsinki, Finland Rinnekoti Foundation, Rinnekodintie 10, FIN 02980 Espoo, Finland Electronic address
    Neuropharmacology 76:729-36. 2014
  2. pmc Altered differentiation of neural stem cells in fragile X syndrome
    Maija Castrén
    Neuroscience Center, University of Helsinki, P O Box 56, 00014 Helsinki, Finland
    Proc Natl Acad Sci U S A 102:17834-9. 2005
  3. ncbi request reprint Differentiation of neuronal cells in fragile X syndrome
    Maija Castrén
    Department of Medical Genetics and Neuroscience Center, University of Helsinki, Helsinki, Finland
    Cell Cycle 5:1528-30. 2006
  4. doi request reprint Neural stem cells
    Maija Castrén
    Institute of Biomedicine Physiology, University of Helsinki, Helsinki, Finland
    Results Probl Cell Differ 54:33-40. 2012
  5. ncbi request reprint Overexpression of a truncated TrkB isoform increases the proliferation of neural progenitors
    Topi A Tervonen
    Neuroscience Center, University of Helsinki, PO Box 56, 00014 Helsinki, Finland
    Eur J Neurosci 24:1277-85. 2006
  6. ncbi request reprint Rgs4 mRNA expression is decreased in the brain of Fmr1 knockout mouse
    Topi Tervonen
    Neuroscience Center, University of Helsinki, P O Box 56, Viikinkaari 4, FIN 00014 Helsinki, Finland
    Brain Res Mol Brain Res 133:162-5. 2005
  7. ncbi request reprint Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus
    Mikko Sairanen
    Neuroscience Center, University of Helsinki, 00014 Helsinki, Finland
    J Neurosci 25:1089-94. 2005

Collaborators

Detail Information

Publications7

  1. ncbi request reprint BDNF in fragile X syndrome
    Maija L Castrén
    Institute of Biomedicine Physiology, University of Helsinki, P O Box 63, FIN 00014 Helsinki, Finland Rinnekoti Foundation, Rinnekodintie 10, FIN 02980 Espoo, Finland Electronic address
    Neuropharmacology 76:729-36. 2014
    ..Here, we review the evidence of the role for BDNF in the developing and adult FXS brain. This article is part of the Special Issue entitled 'BDNF Regulation of Synaptic Structure, Function, and Plasticity'...
  2. pmc Altered differentiation of neural stem cells in fragile X syndrome
    Maija Castrén
    Neuroscience Center, University of Helsinki, P O Box 56, 00014 Helsinki, Finland
    Proc Natl Acad Sci U S A 102:17834-9. 2005
    ..These results demonstrate substantial alterations in the early maturation of FMRP-deficient neural stem cells in fragile X syndrome and in the fmr1-KO mice...
  3. ncbi request reprint Differentiation of neuronal cells in fragile X syndrome
    Maija Castrén
    Department of Medical Genetics and Neuroscience Center, University of Helsinki, Helsinki, Finland
    Cell Cycle 5:1528-30. 2006
    ..Here, alterations of neuronal cell differentiation in fragile X syndrome, the implications of our recent findings, and some open questions that need to be addressed, are discussed...
  4. doi request reprint Neural stem cells
    Maija Castrén
    Institute of Biomedicine Physiology, University of Helsinki, Helsinki, Finland
    Results Probl Cell Differ 54:33-40. 2012
    ....
  5. ncbi request reprint Overexpression of a truncated TrkB isoform increases the proliferation of neural progenitors
    Topi A Tervonen
    Neuroscience Center, University of Helsinki, PO Box 56, 00014 Helsinki, Finland
    Eur J Neurosci 24:1277-85. 2006
    ..The data indicate that changes in the relative expression levels of different TrkB isoforms influence the replicative capacity of neural progenitors...
  6. ncbi request reprint Rgs4 mRNA expression is decreased in the brain of Fmr1 knockout mouse
    Topi Tervonen
    Neuroscience Center, University of Helsinki, P O Box 56, Viikinkaari 4, FIN 00014 Helsinki, Finland
    Brain Res Mol Brain Res 133:162-5. 2005
    ..The expression of Rgs4 was normal in animals lacking a related protein, FXR2P, indicating that the decrease in Rgs4 expression was specific for the absence of FMRP, and suggests a role for FMRP in G-protein signaling...
  7. ncbi request reprint Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus
    Mikko Sairanen
    Neuroscience Center, University of Helsinki, 00014 Helsinki, Finland
    J Neurosci 25:1089-94. 2005
    ..These data suggest that antidepressants increase turnover of hippocampal neurons rather than neurogenesis per se and that BDNF signaling is required for the long-term survival of newborn neurons in mouse hippocampus...