Genomes and Genes

Mikael Brosché


Affiliation: University of Helsinki
Country: Finland


  1. Xu E, Vaahtera L, Brosché M. Roles of Defense Hormones in the Regulation of Ozone-Induced Changes in Gene Expression and Cell Death. Mol Plant. 2015;8:1776-94 pubmed publisher
    ..In response to apoplastic ROS, there is not a single signaling pathway that regulates gene expression or cell death. Instead, several pathways regulate the apoplastic ROS response via combinatorial or overlapping mechanisms. ..
  2. Kaurilind E, Xu E, Brosché M. A genetic framework for H2O2 induced cell death in Arabidopsis thaliana. BMC Genomics. 2015;16:837 pubmed publisher
    ..The hormones salicylic acid, jasmonic acid and auxin, as well as their interaction, are crucial determinants of cell death regulation. ..
  3. Brosché M, Kangasjärvi J. Low antioxidant concentrations impact on multiple signalling pathways in Arabidopsis thaliana partly through NPR1. J Exp Bot. 2012;63:1849-61 pubmed publisher
    ..Overall, low ascorbic acid concentrations mostly led to opposite phenotypes to low glutathione concentrations, and both antioxidants interacted with SA and JA signalling pathways. ..
  4. Idänheimo N, Gauthier A, Salojärvi J, Siligato R, Brosché M, Kollist H, et al. The Arabidopsis thaliana cysteine-rich receptor-like kinases CRK6 and CRK7 protect against apoplastic oxidative stress. Biochem Biophys Res Commun. 2014;445:457-62 pubmed publisher
    ..CRK6 and CRK7 are active protein kinases with differential preference for divalent cations. Our results suggest that CRK7 is involved in mediating the responses to extracellular but not chloroplastic ROS production. ..