Affiliation: University of Turku
- Role of cytoskeleton components in measles virus replicationH Berghäll
Department of Virology, University of Turku, Turku, Finland
Arch Virol 149:891-901. 2004..We also investigated a possible role for proteins of the ERM-family. Our results support an important role for actin filaments and microtubules for efficient MV replication...
- The interferon-inducible RNA helicase, mda-5, is involved in measles virus-induced expression of antiviral cytokinesHeidi Berghäll
Department of Virology, University of Turku, Kiinamyllynkatu 13, FIN 20520 Turku, Finland
Microbes Infect 8:2138-44. 2006..Forced expression of mda-5, but not that of RIG-I or TLR3, leads to enhanced IFN-beta promoter activity in MV-infected A549 cells. Our results suggest that IFN-inducible mda-5 is involved in MV-induced expression of antiviral cytokines...
- NuMA and nuclear lamins are cleaved during viral infection--inhibition of caspase activity prevents cleavage and rescues HeLa cells from measles virus-induced but not from rhinovirus 1B-induced cell deathPekka Taimen
Department of Pathology, University of Turku, Kiinamyllynkatu 10, FIN 20520 Turku, Finland
Virology 320:85-98. 2004..Interestingly, z-VAD-FMK rescued MV-infected but not HRV 1B-infected cells from cell death. These results show for the first time that NuMA and lamins are specific target proteins during virus-induced programmed cell death...