J Antonen

Summary

Affiliation: University of Tampere
Country: Finland

Publications

  1. ncbi Interleukin-1 beta, interleukin-1 receptor antagonist and interleukin-6 plasma levels and cytokine gene polymorphisms in chronic lymphocytic leukemia: correlation with prognostic parameters
    J Hulkkonen
    Department of Microbiology and Immunology, University of Tampere Medical School, Tampere, Finland
    Haematologica 85:600-6. 2000
  2. ncbi A rare allele combination of the interleukin-1 gene complex is associated with high interleukin-1 beta plasma levels in healthy individuals
    J Hulkkonen
    Institute of Medical Technology, University of Tampere, Tampere, Finland
    Eur Cytokine Netw 11:251-5. 2000
  3. ncbi Matrix metalloproteinase 9 (MMP-9) gene polymorphism and MMP-9 plasma levels in primary Sjogren's syndrome
    J Hulkkonen
    Department of Microbiology and Immunology, Medical School, FIN 33014, University of Tampere, Finland
    Rheumatology (Oxford) 43:1476-9. 2004
  4. ncbi Elevated interleukin-6 plasma levels are regulated by the promoter region polymorphism of the IL6 gene in primary Sjögren's syndrome and correlate with the clinical manifestations of the disease
    J Hulkkonen
    Institute of Medical Technology, University of Tampere, Tampere, Finland
    Rheumatology (Oxford) 40:656-61. 2001
  5. ncbi Genetic association between interleukin-10 promoter region polymorphisms and primary Sjögren's syndrome
    J Hulkkonen
    Department of Microbiology and Immunology, University of Tampere Medical School and Institute of Medical Technology, Finland
    Arthritis Rheum 44:176-9. 2001
  6. ncbi Increased in vitro production of interleukin 6 in response to trimethoprim among persons with trimethoprim induced systemic adverse reactions
    J Antonen
    Department of Medicine, Tampere University Hospital, Medical School, University of Tampere, Finland
    J Rheumatol 26:2585-90. 1999
  7. ncbi Severe antibody-mediated human insulin resistance: successful treatment with the insulin analog lispro. A case report
    J T Lahtela
    Department of Medicine, University of Tampere, Finland
    Diabetes Care 20:71-3. 1997
  8. doi Reactive arthritis in a population exposed to an extensive waterborne gastroenteritis outbreak after sewage contamination in Pirkanmaa, Finland
    T Uotila
    Centre for Rheumatic Diseases, Tampere University Hospital, Tampere, Finland
    Scand J Rheumatol 40:358-62. 2011
  9. ncbi Presence of apolipoprotein E epsilon4 allele predisposes to early onset of primary Sjogren's syndrome
    M Pertovaara
    Department of Internal Medicine, Section of Rheumatology, Tampere University Hospital, P O Box 2000, FIN 33521 Tampere, Finland
    Rheumatology (Oxford) 43:1484-7. 2004
  10. pmc Th2 cytokine genotypes are associated with a milder form of primary Sjogren's syndrome
    M Pertovaara
    Department of Internal Medicine, Section of Rheumatology, Tampere University Hospital, PO Box 2000, FIN 33521 Tampere, Finland
    Ann Rheum Dis 65:666-70. 2006

Collaborators

Detail Information

Publications12

  1. ncbi Interleukin-1 beta, interleukin-1 receptor antagonist and interleukin-6 plasma levels and cytokine gene polymorphisms in chronic lymphocytic leukemia: correlation with prognostic parameters
    J Hulkkonen
    Department of Microbiology and Immunology, University of Tampere Medical School, Tampere, Finland
    Haematologica 85:600-6. 2000
    ..As the plasma levels of IL-6, IL-1 beta and IL-1Ra have been suggested to be partly dependent on gene polymorphism, the previously described polymorphisms of the IL-1 complex genes and the IL-6 gene were also studied...
  2. ncbi A rare allele combination of the interleukin-1 gene complex is associated with high interleukin-1 beta plasma levels in healthy individuals
    J Hulkkonen
    Institute of Medical Technology, University of Tampere, Tampere, Finland
    Eur Cytokine Netw 11:251-5. 2000
    ..This effect of IL-1 alpha 2.2 homozygosity was more pronounced in donors, who also were carriers of the IL-1 beta allele 2. Thus these data suggest that this allele combination has a regulatory effect on basal IL-1 beta production...
  3. ncbi Matrix metalloproteinase 9 (MMP-9) gene polymorphism and MMP-9 plasma levels in primary Sjogren's syndrome
    J Hulkkonen
    Department of Microbiology and Immunology, Medical School, FIN 33014, University of Tampere, Finland
    Rheumatology (Oxford) 43:1476-9. 2004
    ..To determine whether plasma matrix metalloproteinase 9 (MMP-9) and MMP9 (-1562C-->T) polymorphism have an effect on the disease phenotype in primary Sjogren's syndrome (pSS)...
  4. ncbi Elevated interleukin-6 plasma levels are regulated by the promoter region polymorphism of the IL6 gene in primary Sjögren's syndrome and correlate with the clinical manifestations of the disease
    J Hulkkonen
    Institute of Medical Technology, University of Tampere, Tampere, Finland
    Rheumatology (Oxford) 40:656-61. 2001
    ....
  5. ncbi Genetic association between interleukin-10 promoter region polymorphisms and primary Sjögren's syndrome
    J Hulkkonen
    Department of Microbiology and Immunology, University of Tampere Medical School and Institute of Medical Technology, Finland
    Arthritis Rheum 44:176-9. 2001
    ..To determine whether the haplotypes formed on the basis of single-base-exchange polymorphisms at positions -1082, -819, or -592 of the interleukin-10 (IL-10) gene predispose subjects to primary Sjögren's syndrome (SS)...
  6. ncbi Increased in vitro production of interleukin 6 in response to trimethoprim among persons with trimethoprim induced systemic adverse reactions
    J Antonen
    Department of Medicine, Tampere University Hospital, Medical School, University of Tampere, Finland
    J Rheumatol 26:2585-90. 1999
    ....
  7. ncbi Severe antibody-mediated human insulin resistance: successful treatment with the insulin analog lispro. A case report
    J T Lahtela
    Department of Medicine, University of Tampere, Finland
    Diabetes Care 20:71-3. 1997
    ..To evaluate the efficacy of the insulin analog lispro (Lys B28, Pro B29) in severe insulin resistance caused by human insulin antibodies...
  8. doi Reactive arthritis in a population exposed to an extensive waterborne gastroenteritis outbreak after sewage contamination in Pirkanmaa, Finland
    T Uotila
    Centre for Rheumatic Diseases, Tampere University Hospital, Tampere, Finland
    Scand J Rheumatol 40:358-62. 2011
    ..To assess the occurrence, clinical picture, and triggering infections of reactive arthritis (ReA) associated with a large waterborne gastroenteritis outbreak...
  9. ncbi Presence of apolipoprotein E epsilon4 allele predisposes to early onset of primary Sjogren's syndrome
    M Pertovaara
    Department of Internal Medicine, Section of Rheumatology, Tampere University Hospital, P O Box 2000, FIN 33521 Tampere, Finland
    Rheumatology (Oxford) 43:1484-7. 2004
    ..Apolipoprotein E (apoE) polymorphism plays a central role in lipid metabolism, but has recently also been suggested to regulate inflammation, as judged by levels of serum C-reactive protein (CRP)...
  10. pmc Th2 cytokine genotypes are associated with a milder form of primary Sjogren's syndrome
    M Pertovaara
    Department of Internal Medicine, Section of Rheumatology, Tampere University Hospital, PO Box 2000, FIN 33521 Tampere, Finland
    Ann Rheum Dis 65:666-70. 2006
    ..Immunohistological studies on salivary and lacrimal glands have yielded conflicting results on the Th1/Th2 balance in primary Sjögren's syndrome (pSS)...
  11. ncbi Polymorphism of the tumour necrosis factor-alpha gene at position -308 and renal manifestations of primary Sjögren's syndrome
    M Pertovaara
    Rheumatology (Oxford) 43:106-7. 2004
  12. ncbi The significance of mannan-binding lectin gene alleles in patients with primary Sjögren's syndrome
    J Aittoniemi
    Department of Clinical Microbiology, Centre for Laboratory Medicine, Tampere University Hospital, Finland
    Scand J Rheumatol 31:362-5. 2002
    ..To investigate the significance or mannan-binding lectin (MBL) gene alleles in patients with primary Sjogren's syndrome (pSS). Genotypes were determined in 65 pSS patients and 138 controls...