Teija L T Aho

Summary

Affiliation: University of Turku
Country: Finland

Publications

  1. pmc Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity
    Teija L T Aho
    Turku Centre for Biotechnology, University of Turku, Tykistökatu 6 B, 20520 Turku, Finland
    BMC Cell Biol 7:21. 2006
  2. ncbi request reprint Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site
    Teija L T Aho
    Turku Centre for Biotechnology, University of Turku Abo Akademi University, Tykistökatu 6 B, 20520 Turku, Finland
    FEBS Lett 571:43-9. 2004
  3. pmc Expression of human pim family genes is selectively up-regulated by cytokines promoting T helper type 1, but not T helper type 2, cell differentiation
    Teija L T Aho
    Turku Centre for Biotechnology, University of Turku Abo Akademi University, Turku, Finland
    Immunology 116:82-8. 2005
  4. ncbi request reprint Pim-1 kinase enhances NFATc activity and neuroendocrine functions in PC12 cells
    Margarita Glazova
    Turku Centre for Biotechnology, University of Turku Abo Akademi University, Tykistökatu 6 B, FI 20520 Turku, Finland
    Brain Res Mol Brain Res 138:116-23. 2005
  5. ncbi request reprint Pim-1 kinase inhibits STAT5-dependent transcription via its interactions with SOCS1 and SOCS3
    Katriina J Peltola
    Turku Centre for Biotechnology, University of Turku Abo Akademi University, Turku, Finland
    Blood 103:3744-50. 2004

Detail Information

Publications5

  1. pmc Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity
    Teija L T Aho
    Turku Centre for Biotechnology, University of Turku, Tykistökatu 6 B, 20520 Turku, Finland
    BMC Cell Biol 7:21. 2006
    ..The Runx genes encode alpha-subunits of heterodimeric transcription factors which regulate cell proliferation and differentiation in various tissues during development and which can become leukemogenic upon aberrant expression...
  2. ncbi request reprint Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site
    Teija L T Aho
    Turku Centre for Biotechnology, University of Turku Abo Akademi University, Tykistökatu 6 B, 20520 Turku, Finland
    FEBS Lett 571:43-9. 2004
    ..Our results suggest that phosphorylation of Bad by Pim-1 is one of several mechanisms via which the Pim-1 kinase can enhance Bcl-2 activity and promote cell survival...
  3. pmc Expression of human pim family genes is selectively up-regulated by cytokines promoting T helper type 1, but not T helper type 2, cell differentiation
    Teija L T Aho
    Turku Centre for Biotechnology, University of Turku Abo Akademi University, Turku, Finland
    Immunology 116:82-8. 2005
    ..Taken together, our results suggest that pim genes and their protein products are involved in the early differentiation process of T helper cells...
  4. ncbi request reprint Pim-1 kinase enhances NFATc activity and neuroendocrine functions in PC12 cells
    Margarita Glazova
    Turku Centre for Biotechnology, University of Turku Abo Akademi University, Tykistökatu 6 B, FI 20520 Turku, Finland
    Brain Res Mol Brain Res 138:116-23. 2005
    ..Interestingly, Pim-1 can synergize with forskolin-induced signaling pathways to stimulate also neuroendocrine functions of PC12 cells...
  5. ncbi request reprint Pim-1 kinase inhibits STAT5-dependent transcription via its interactions with SOCS1 and SOCS3
    Katriina J Peltola
    Turku Centre for Biotechnology, University of Turku Abo Akademi University, Turku, Finland
    Blood 103:3744-50. 2004
    ..Thus, both Pim and SOCS family proteins may be components of a negative feedback mechanism that allows STAT5 to attenuate its own activity...