Elisa Närvä

Summary

Affiliation: Turku Centre for Biotechnology
Country: Finland

Publications

  1. doi request reprint High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity
    Elisa Närvä
    Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku, Finland
    Nat Biotechnol 28:371-7. 2010
  2. pmc High-throughput karyotyping of human pluripotent stem cells
    Riikka J Lund
    Molecular and Systems Immunology and Stem Cell Biology, Turku Centre for Biotechnology, University of Turku and Abo Akademi University, FI 20520 Turku, Finland
    Stem Cell Res 9:192-5. 2012
  3. pmc RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation
    Elisa Närvä
    Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku, Finland
    Stem Cells 30:452-60. 2012

Detail Information

Publications3

  1. doi request reprint High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity
    Elisa Närvä
    Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku, Finland
    Nat Biotechnol 28:371-7. 2010
    ..Furthermore, LOH of the q arm of chromosome 16, which has not been observed previously in hESCs, was detected...
  2. pmc High-throughput karyotyping of human pluripotent stem cells
    Riikka J Lund
    Molecular and Systems Immunology and Stem Cell Biology, Turku Centre for Biotechnology, University of Turku and Abo Akademi University, FI 20520 Turku, Finland
    Stem Cell Res 9:192-5. 2012
    ..The analysis can be performed from low amounts of DNA isolated from whole cell pools with simple data analysis interface. The method enables routine screening of stem cell lines in a cost-efficient high-throughput manner...
  3. pmc RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation
    Elisa Närvä
    Turku Centre for Biotechnology, University of Turku and Abo Akademi University, Turku, Finland
    Stem Cells 30:452-60. 2012
    ..Thus, we hypothesize that L1TD1 is part of the L1TD1-RHA-LIN28 complex that could influence levels of OCT4. Our results strongly suggest that L1TD1 has an important role in the regulation of stemness...