J Sivenius

Summary

Country: Finland

Publications

  1. ncbi request reprint [Rehabilitation possibilities for stroke patients in the future]
    Juhani Sivenius
    Kuopion yliopisto, neurotieteen ja neurologian klinikka Suomen aivotutkimus ja kuntoutuskeskus Neuron 71130 Kortejoki
    Duodecim 118:2569-76. 2002
  2. ncbi request reprint Continuous 15-year decrease in incidence and mortality of stroke in Finland: the FINSTROKE study
    Juhani Sivenius
    University Hospital of Kuopio, Brain Research and Rehabilitation Center Neuron, Kuopio, Finland
    Stroke 35:420-5. 2004
  3. ncbi request reprint Antiplatelet treatment does not reduce the severity of subsequent stroke. European Stroke Prevention Study 2 Working Group
    J Sivenius
    Department of Neurology, University of Kuopio, Finland
    Neurology 53:825-9. 1999
  4. ncbi request reprint Selegiline treatment facilitates recovery after stroke
    J Sivenius
    Department of Neuroscience and Neurology, University of Kuopio, Finland
    Neurorehabil Neural Repair 15:183-90. 2001
  5. ncbi request reprint Studies on the influence of enriched-environment housing combined with systemic administration of an alpha2-adrenergic antagonist on spatial learning and hyperactivity after global ischemia in rats
    K Puurunen
    A I Virtanen Institute, University of Kuopio, Finland
    Stroke 28:623-31. 1997
  6. ncbi request reprint Cardiac power during exercise and the risk of stroke in men
    S Kurl
    Research Institute of Public Health, University of Kuopio, Kuopio, Finland
    Stroke 36:820-4. 2005
  7. doi request reprint Exercise workload, cardiovascular risk factor evaluation and the risk of stroke in middle-aged men
    S Kurl
    Research Institute of Public Health Unit, School of Public Health and Clinical Nutrition, University of Kuopio, Kuopio, Finland
    J Intern Med 265:229-37. 2009
  8. ncbi request reprint Systolic blood pressure response to exercise stress test and risk of stroke
    S Kurl
    Research Institute of Public Health, Department of Public Health and General Practice, University of Kuopio, Finland
    Stroke 32:2036-41. 2001
  9. ncbi request reprint Neuroprotection by the alpha2-adrenoceptor agonist, dexmedetomidine, in rat focal cerebral ischemia
    J Jolkkonen
    Department of Neurology, University of Kuopio, Finland
    Eur J Pharmacol 372:31-6. 1999
  10. ncbi request reprint Behavioral effects of the alpha(2)-adrenoceptor antagonist, atipamezole, after focal cerebral ischemia in rats
    J Jolkkonen
    Department of Neuroscience and Neurology, A I Virtanen Institute, University of Kuopio, P O Box 1627, 70211, Kuopio, Finland
    Eur J Pharmacol 400:211-9. 2000

Collaborators

Detail Information

Publications51

  1. ncbi request reprint [Rehabilitation possibilities for stroke patients in the future]
    Juhani Sivenius
    Kuopion yliopisto, neurotieteen ja neurologian klinikka Suomen aivotutkimus ja kuntoutuskeskus Neuron 71130 Kortejoki
    Duodecim 118:2569-76. 2002
  2. ncbi request reprint Continuous 15-year decrease in incidence and mortality of stroke in Finland: the FINSTROKE study
    Juhani Sivenius
    University Hospital of Kuopio, Brain Research and Rehabilitation Center Neuron, Kuopio, Finland
    Stroke 35:420-5. 2004
    ..The purpose of this study was to analyze the incidence and mortality trends in stroke events among persons 25 to 74 years of age in Finland during 1983 to 1997...
  3. ncbi request reprint Antiplatelet treatment does not reduce the severity of subsequent stroke. European Stroke Prevention Study 2 Working Group
    J Sivenius
    Department of Neurology, University of Kuopio, Finland
    Neurology 53:825-9. 1999
    ..To assess the the effect of antiplatelet therapy on the severity of subsequent stroke in patients with stroke and TIA...
  4. ncbi request reprint Selegiline treatment facilitates recovery after stroke
    J Sivenius
    Department of Neuroscience and Neurology, University of Kuopio, Finland
    Neurorehabil Neural Repair 15:183-90. 2001
    ..The aim of this study was to investigate whether the systemic administration of selegiline facilitates recovery after a cerebral infarction in humans...
  5. ncbi request reprint Studies on the influence of enriched-environment housing combined with systemic administration of an alpha2-adrenergic antagonist on spatial learning and hyperactivity after global ischemia in rats
    K Puurunen
    A I Virtanen Institute, University of Kuopio, Finland
    Stroke 28:623-31. 1997
    ....
  6. ncbi request reprint Cardiac power during exercise and the risk of stroke in men
    S Kurl
    Research Institute of Public Health, University of Kuopio, Kuopio, Finland
    Stroke 36:820-4. 2005
    ..The aim of this study was to examine the relationship of exercise cardiac power (ECP), defined as a ratio of VO2max with peak systolic blood pressure (SBP) during exercise, with the risk for stroke...
  7. doi request reprint Exercise workload, cardiovascular risk factor evaluation and the risk of stroke in middle-aged men
    S Kurl
    Research Institute of Public Health Unit, School of Public Health and Clinical Nutrition, University of Kuopio, Kuopio, Finland
    J Intern Med 265:229-37. 2009
    ..Background. There are no data on exercise workload combined with European Systematic Coronary Risk Evaluation (SCORE) in the prediction of stroke...
  8. ncbi request reprint Systolic blood pressure response to exercise stress test and risk of stroke
    S Kurl
    Research Institute of Public Health, Department of Public Health and General Practice, University of Kuopio, Finland
    Stroke 32:2036-41. 2001
    ..Exercise SBP testing may be recommended as an additional tool in the prediction of future stroke...
  9. ncbi request reprint Neuroprotection by the alpha2-adrenoceptor agonist, dexmedetomidine, in rat focal cerebral ischemia
    J Jolkkonen
    Department of Neurology, University of Kuopio, Finland
    Eur J Pharmacol 372:31-6. 1999
    ..Its neuroprotective efficacy was better than that produced by CGS-19775, and dexmedetomidine was safer with respect to kidney toxicity when compared to NBQX...
  10. ncbi request reprint Behavioral effects of the alpha(2)-adrenoceptor antagonist, atipamezole, after focal cerebral ischemia in rats
    J Jolkkonen
    Department of Neuroscience and Neurology, A I Virtanen Institute, University of Kuopio, P O Box 1627, 70211, Kuopio, Finland
    Eur J Pharmacol 400:211-9. 2000
    ..These results suggest that repeated use-dependent release of noradrenaline by atipamezole facilitates the sensorimotor recovery following focal cerebral ischemia in rats...
  11. ncbi request reprint Combined diffusion and perfusion MRI with correlation to single-photon emission CT in acute ischemic stroke. Ischemic penumbra predicts infarct growth
    J O Karonen
    Department of Clinical Radiology, Clinical Physiology and Nuclear Medicine, Kuopio, Finland
    Stroke 30:1583-90. 1999
    ..The purpose of this study was to determine whether combined DWI and PWI in acute (<24 hours) ischemic stroke can predict infarct growth and final size...
  12. ncbi request reprint Association of exercise-induced, silent ST-segment depression with the risk of stroke and cardiovascular diseases in men
    S Kurl
    Research Institute of Public Health, Kuopio, Finland
    Stroke 34:1760-5. 2003
    ..In this prospective study, we investigated the relation of silent myocardial ischemia and the risk of stroke and CVD death in men with and without conventional risk factors...
  13. ncbi request reprint Enriched-environment housing increases neuronal Fos-staining in the dentate gyrus after a water maze spatial learning task
    K Puurunen
    Department of Neuroscience and Neurology, University of Kuopio, PO Box 1627, SF 70211, Kuopio, Finland
    Neuropharmacology 40:440-7. 2001
    ..The altered gene expression is also preserved in ischemic rats...
  14. pmc Delirium episode as a sign of undetected dementia among community dwelling elderly subjects: a 2 year follow up study
    T Rahkonen
    Brain Research and Rehabilitation Center Neuron, Kuopio, Finland
    J Neurol Neurosurg Psychiatry 69:519-21. 2000
    ..One case of alcoholic dementia and one case of a non-alcoholic hepatic encephalopathia were also found. A delirium episode is often the first sign of dementia requiring attention from medical and social professionals...
  15. ncbi request reprint An alpha(2)-adrenergic antagonist, atipamezole, facilitates behavioral recovery after focal cerebral ischemia in rats
    K Puurunen
    Department of Neuroscience and Neurology, University of Kuopio, PO Box 1627, SF 70211 Kuopio, Finland
    Neuropharmacology 40:597-606. 2001
    ....
  16. doi request reprint Comparison of the Behavioural Inattention Test and the Catherine Bergego Scale in assessment of hemispatial neglect
    R Luukkainen-Markkula
    Brain Research and Rehabilitation Center Neuron, Kuopio, Finland
    Neuropsychol Rehabil 21:103-16. 2011
    ..Specific rehabilitation methods might also be needed in neglect with or without hemianopia...
  17. doi request reprint Plasma N-terminal fragments of natriuretic peptides predict the risk of stroke and atrial fibrillation in men
    S Kurl
    Research Institute of Public Health, University of Kuopio, PO Box 1627, Kuopio 70211, Finland
    Heart 95:1067-71. 2009
    ..Prognostic value of natriuretic peptides has been established in patients with heart failure. However, the prognostic significance of natriuretic peptides with respect to stroke is not well known in general populations...
  18. doi request reprint Rehabilitation of hemispatial neglect: A randomized study using either arm activation or visual scanning training
    R Luukkainen-Markkula
    Brain Research and Rehabilitation Center Neuron, Kuopio, Finland
    Restor Neurol Neurosci 27:663-72. 2009
    ..The aim of this study was to determine whether left arm activation alone could be sufficient to produce a long lasting amelioration of neglect comparable to the effect obtained with traditional visual scanning training...
  19. doi request reprint Hemispatial neglect reflected on visual memory
    R Luukkainen-Markkula
    Brain Research and Rehabilitation Center Neuron, Kuopio, Finland
    Restor Neurol Neurosci 29:321-30. 2011
    ..The aim of this study was to investigate, how neglect would be reflected in their performances in commonly used clinical visual memory tests...
  20. ncbi request reprint MAO-B inhibition by a single dose of l-deprenyl or lazabemide does not prevent neuronal damage following focal cerebral ischaemia in rats
    J Jolkkonen
    Department of Neuroscience and Neurology, University of Kuopio, Finland
    Pharmacol Toxicol 87:242-5. 2000
    ....
  21. ncbi request reprint Selegiline treatment after transient global ischemia in gerbils enhances the survival of CA1 pyramidal cells in the hippocampus
    H Lahtinen
    A I Virtanen Institute, University of Kuopio, Finland
    Brain Res 757:260-7. 1997
    ..5). The results show that a low dose of selegiline can alleviate the delayed hippocampal neuronal death in gerbils when administered 2 h after an ischemic insult...
  22. ncbi request reprint Low serum lycopene concentration is associated with an excess incidence of acute coronary events and stroke: the Kuopio Ischaemic Heart Disease Risk Factor Study
    T H Rissanen
    Research Institute of Public Health, University of Kuopio, PO Box 1627, FIN-70211, Kuopio, Finland
    Br J Nutr 85:749-54. 2001
    ..Our study suggests that a low serum level of lycopene is associated with an increased risk of atherosclerotic vascular events in middle-aged men previously free of CHD and stroke...
  23. ncbi request reprint Hyperinsulinemia and the risk of cardiovascular death and acute coronary and cerebrovascular events in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
    H M Lakka
    Research Institute of Public Health, University of Kuopio, Finland
    Arch Intern Med 160:1160-8. 2000
    ..The role of hyperinsulinemia as a cardiovascular risk factor is controversial. We studied whether hyperinsulinemia is independently associated with increased cardiovascular morbidity and mortality...
  24. ncbi request reprint Diffusion and perfusion MR imaging in acute ischemic stroke: a comparison to SPECT
    J O Karonen
    Department of Radiology, Kuopio University Hospital, Kuopio, Finland
    Comput Methods Programs Biomed 66:125-8. 2001
    ..001). In conclusion, combined DWI and PWI is a powerful tool in evaluating the hemodynamics of acute ischemic stroke and can predict the infarct growth during 1 week...
  25. ncbi request reprint Effects of dexmedetomidine after transient and permanent occlusion of the middle cerebral artery in the rat
    J Kuhmonen
    Department of Neurology, University of Kuopio, Finland
    J Neural Transm 108:261-71. 2001
    ..9%) and in the striatum (20.3%) after transient occlusion. Additionally, dexmedetomidine caused significant variations in the physiological parameters...
  26. ncbi request reprint Hangover and the risk of stroke in middle-aged men
    S H Rantakömi
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
    Acta Neurol Scand 127:186-91. 2013
    ..The aim of this study was to examine the association between hangover and the risk of stroke...
  27. doi request reprint Modelling the burden of stroke in Finland until 2030
    J Sivenius
    University Hospital of Kuopio, Brain Research and Rehabilitation Center Neuron Kuopio, Finland
    Int J Stroke 4:340-5. 2009
    ..Therefore, it has been a common belief in many countries including Finland that the numbers of stroke patients will increase considerably during the next two decades because the population is rapidly ageing...
  28. ncbi request reprint Systematic intervention for supporting community care of elderly people after a delirium episode
    T Rahkonen
    Brain Research and Rehabilitation Center, Neuron, Kuopio, Finland
    Int Psychogeriatr 13:37-49. 2001
    ..To investigate the effects of a systematic intervention with a case manager concept and rehabilitation periods compared to standard aftercare in elderly community-dwelling patients discharged from the hospital after a delirium episode...
  29. ncbi request reprint Cutaneous electrical stimulation may enhance sensorimotor recovery in chronic stroke
    S H Peurala
    Brain Research and Rehabilitation Center Neuron, Kuopio, Finland
    Clin Rehabil 16:709-16. 2002
    ..To investigate whether cutaneous electrical stimulation has a role in the enhancement of sensorimotor function in chronic stroke...
  30. ncbi request reprint Assessing the outcome of stroke: a comparison between MRI and clinical stroke scales
    J Nuutinen
    Department of Neurology, Kuopio University Hospital, Kuopio, Finland
    Acta Neurol Scand 113:100-7. 2006
    ..The ability of DWI and PWI to predict the outcome was compared with the ability of clinical stroke scales to predict the outcome...
  31. ncbi request reprint Differential effect of the alpha2-adrenoceptor antagonist, atipamezole, in limb-placing task and skilled forepaw use following experimental stroke
    S Butovas
    Department of Neuroscience and Neurology, University of Kuopio, Kuopio, Finland
    Restor Neurol Neurosci 18:143-51. 2001
    ..This is in contrast to spontaneous recovery and recovery-enhancing effects of atipamezole in the limb-placing test, particularly in the transient MCA occlusion model...
  32. ncbi request reprint Plasma vitamin C modifies the association between hypertension and risk of stroke
    S Kurl
    Research Institute of Public Health, University of Kuopio, Kuopio, Finland
    Stroke 33:1568-73. 2002
    ..We sought to examine whether plasma vitamin C modifies the association between overweight and hypertension and the risk of stroke in middle-aged men from eastern Finland...
  33. ncbi request reprint Effects of supporting community-living demented patients and their caregivers: a randomized trial
    U Eloniemi-Sulkava
    Department of Public Health and General Practice, University of Kuopio, Finland
    J Am Geriatr Soc 49:1282-7. 2001
    ..On the basis of our experiences, we suggest that intervention by a dementia family care coordinator should be targeted especially at patients with problems threatening the continuity of community care...
  34. ncbi request reprint Eleven-year trends of stroke in Turku, Finland
    Pirjo Immonen-Räihä
    General Practice, Raisio Region Hospital, University of Turku, Turku, Finland
    Neuroepidemiology 22:196-203. 2003
    ..Due to an increase in elderly people in the background population, the total number of strokes remained stable. Thus, in spite of the observed declining trends in incidence, the need for stroke care has not diminished...
  35. ncbi request reprint Declining incidence and mortality of stroke in persons aged > or = 75 years in Finland; the FINSTROKE study
    Aapo Lehtonen
    Turku City Hospital, Turku, Finland
    Eur J Cardiovasc Prev Rehabil 11:466-70. 2004
    ..The aim of the present study was to analyse the trends in incidence, mortality and prognosis of acute stroke events in persons aged > or = 75 years in Finland...
  36. ncbi request reprint The validation of the Finnish Hospital Discharge Register and Causes of Death Register data on stroke diagnoses
    Hanna Tolonen
    Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute KTL, Helsinki, Finland
    Eur J Cardiovasc Prev Rehabil 14:380-5. 2007
    ..The purpose of this study was to evaluate the validity of the Finnish hospital discharge registers and causes of death registers stroke diagnoses against the population-based FINSTROKE register...
  37. ncbi request reprint A long-term video-EEG and behavioral follow-up after endothelin-1 induced middle cerebral artery occlusion in rats
    Heli Karhunen
    A I Virtanen Institute for Molecular Sciences, University of Kuopio, PO Box 1627, FIN 70211 Kuopio, Finland
    Epilepsy Res 72:25-38. 2006
    ..Further studies are needed to investigate the effect of age, genetic background, and location of ET-injection on the development of hyperexcitability and the risk of post-stroke epileptogenesis...
  38. ncbi request reprint Metabolic syndrome and the risk of stroke in middle-aged men
    Sudhir Kurl
    Research Institute of Public Health, University of Kuopio, Kuopio, Finland
    Stroke 37:806-11. 2006
    ..The aim of this study was to examine the relationship of metabolic syndrome, as defined by National Cholesterol Education Program (NCEP) and World Health Organization (WHO) criteria, with the risk for stroke...
  39. ncbi request reprint Cardiorespiratory fitness and the risk for stroke in men
    Sudhir Kurl
    Research Institute of Public Health, University of Kuopio, Kuopio, Finland
    Arch Intern Med 163:1682-8. 2003
    ..We also compared VO(2)max with conventional risk factors as a predictor for future strokes...
  40. ncbi request reprint Footprint peak time and functional ambulation profile reflect the potential for hemiparetic gait recovery
    Ekaterina B Titianova
    Military Medical Academy, Sofia, Bulgaria
    Brain Inj 19:623-31. 2005
    ..Gait disturbances were monitored in patients with chronic stroke with a walkway built with pressure sensors in order to assess whether detailed gait and footprint information could provide verification for the potential for gait recovery...
  41. ncbi request reprint Gait characteristics and functional ambulation profile in patients with chronic unilateral stroke
    Ekaterina B Titianova
    Specialized Hospital of Neurology and Psychiatry St Naum, Sofia, Bulgaria
    Am J Phys Med Rehabil 82:778-86; quiz 787-9, 823. 2003
    ..The purpose of the present study was to assess whether the functional ambulation profile (FAP), calculated from walkway data, is a sensitive measure in the characterization of dissimilar patients with chronic hemiparesis due to stroke...
  42. ncbi request reprint How much exercise does the enhanced gait-oriented physiotherapy provide for chronic stroke patients?
    Sinikka H Peurala
    Brain Research and Rehabilitation Center, Neuron, Kortejoki, 71130 Kuopio, Finland
    J Neurol 251:449-53. 2004
    ..The purpose of this study was to analyse what was the actual amount of exercise and content of the performed exercise of the three-week gait-oriented physiotherapy program for chronic stroke patients in an in-patient setting...
  43. ncbi request reprint Dipyridamole for preventing recurrent ischemic stroke and other vascular events: a meta-analysis of individual patient data from randomized controlled trials
    Jo Leonardi-Bee
    University of Nottingham, Nottingham, UK
    Stroke 36:162-8. 2005
    ..We performed a meta-analysis using individual patient data from relevant randomized controlled trials...
  44. ncbi request reprint [New evidence about the efficiency of rehabilitation after stroke]
    Juhani Sivenius
    Kuopion yliopisto, neurotieteen ja neurologian klinikka ja KYS
    Duodecim 120:2369-71. 2004
  45. ncbi request reprint [What new on the way to the field of stroke prevention?]
    Markku Kaste
    Helsingin yliopisto, HYKS n neurologian klinikka
    Duodecim 118:2553-61. 2002
  46. ncbi request reprint Efficacy of aspirin plus extended-release dipyridamole in preventing recurrent stroke in high-risk populations
    Ralph L Sacco
    Department of Neurology, College of Physicians and Surgeons and the Mailman School of Public Health, Columbia University, Neurological Institute, New York, NY 10032, USA
    Arch Neurol 62:403-8. 2005
    ..To assess the efficacy of aspirin plus extended-release dipyridamole compared with aspirin alone for the prevention of recurrent stroke among high-risk groups...
  47. ncbi request reprint Increased perfusion in motor areas after constraint-induced movement therapy in chronic stroke: a single-photon emission computerized tomography study
    Mervi Kononen
    Department of Clinical Radiology, Kuopio University Hospital, Kuopio, Finland
    J Cereb Blood Flow Metab 25:1668-74. 2005
    ..These changes might be a sign of active reorganization processes after CIMT in the chronic state of stroke...
  48. ncbi request reprint Gait characteristics after gait-oriented rehabilitation in chronic stroke
    Sinikka H Peurala
    Brain Research and Rehabilitation Center Neuron, Kuopio, Finland
    Restor Neurol Neurosci 23:57-65. 2005
    ..To assess the effects of rehabilitation in thirty-seven ambulatory patients with chronic stroke during three weeks in-patient rehabilitation period...
  49. ncbi request reprint Serum homocysteine, folate and risk of stroke: Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study
    Jyrki K Virtanen
    Research Institute of Public Health, University of Kuopio, Kuopio, Finland
    Eur J Cardiovasc Prev Rehabil 12:369-75. 2005
    ..Homocysteine and folate have been suggested to have opposite effects on the risk of stroke, although the results are controversial...
  50. ncbi request reprint The effectiveness of body weight-supported gait training and floor walking in patients with chronic stroke
    Sinikka H Peurala
    Brain Research and Rehabilitation Center Neuron, Kuopio, Finland
    Arch Phys Med Rehabil 86:1557-64. 2005
    ..To compare body weight-supported exercise on a gait trainer with walking exercise overground...
  51. ncbi request reprint Diabetes worsens the outcome of acute ischemic stroke
    Minna M Kaarisalo
    Turku City Hospital, Turku, Finland
    Diabetes Res Clin Pract 69:293-8. 2005
    ..To characterize acute stroke events in diabetic patients in a population-based stroke register and to determine the influence of diabetes on the outcome of acute stroke...