Alexander G Semenov

Summary

Country: Finland

Publications

  1. doi Processing of pro-brain natriuretic peptide is suppressed by O-glycosylation in the region close to the cleavage site
    Alexander G Semenov
    HyTest Ltd, Turku, Finland
    Clin Chem 55:489-98. 2009
  2. doi Processing of pro-B-type natriuretic peptide: furin and corin as candidate convertases
    Alexander G Semenov
    HyTest Ltd, Turku, Finland
    Clin Chem 56:1166-76. 2010
  3. doi Biochemistry of the human B-type natriuretic peptide precursor and molecular aspects of its processing
    Alexander G Semenov
    HyTest Ltd, Turku, Finland
    Clin Chim Acta 412:850-60. 2011
  4. doi Human pro-B-type natriuretic peptide is processed in the circulation in a rat model
    Alexander G Semenov
    HyTest Ltd, Turku, Finland
    Clin Chem 57:883-90. 2011
  5. doi Immunodetection of glycosylated NT-proBNP circulating in human blood
    Karina R Seferian
    HyTest Ltd, Turku, Finland
    Clin Chem 54:866-73. 2008
  6. doi Novel immunoassay for quantification of brain natriuretic peptide and its precursor in human blood
    Natalia N Tamm
    HyTest Ltd, Turku, Finland
    Clin Chem 54:1511-8. 2008
  7. doi Measurement of B-type natriuretic peptide by two assays utilizing antibodies with different epitope specificity
    Natalia N Tamm
    HyTest Ltd, Intelligate, 6th Floor, Joukahaisenkatu 6, 20520 Turku, Finland
    Clin Biochem 44:257-9. 2011
  8. ncbi The brain natriuretic peptide (BNP) precursor is the major immunoreactive form of BNP in patients with heart failure
    Karina R Seferian
    HyTest Ltd, Turku, Finland
    Clin Chem 53:866-73. 2007

Collaborators

  • Natalia N Tamm
  • Fred S Apple
  • Karina R Seferian
  • Alexey G Katrukha
  • Mihail I Krasnoselsky
  • Ekaterina V Koshkina
  • MaryAnn M Murakami
  • Anastasia A Tolstaya
  • Alexander B Postnikov
  • Daria V Serebryanaya
  • Tatiana V Esakova
  • Kadriya S Mukharyamova
  • Vladimir L Filatov
  • Andrei N Kara
  • Anastasya A Tolstaya

Detail Information

Publications8

  1. doi Processing of pro-brain natriuretic peptide is suppressed by O-glycosylation in the region close to the cleavage site
    Alexander G Semenov
    HyTest Ltd, Turku, Finland
    Clin Chem 55:489-98. 2009
    ..The study of proBNP processing mechanisms is important, because processing impairments could be associated with the development of heart failure (HF)...
  2. doi Processing of pro-B-type natriuretic peptide: furin and corin as candidate convertases
    Alexander G Semenov
    HyTest Ltd, Turku, Finland
    Clin Chem 56:1166-76. 2010
    ..We investigated the role of 2 candidate convertases, furin and corin, in human proBNP processing...
  3. doi Biochemistry of the human B-type natriuretic peptide precursor and molecular aspects of its processing
    Alexander G Semenov
    HyTest Ltd, Turku, Finland
    Clin Chim Acta 412:850-60. 2011
    ..The aim of the present review is to summarize the available data in the field of human proBNP maturation and processing and to discuss potential clinical implications...
  4. doi Human pro-B-type natriuretic peptide is processed in the circulation in a rat model
    Alexander G Semenov
    HyTest Ltd, Turku, Finland
    Clin Chem 57:883-90. 2011
    ..The goals of the present study were to examine whether processing of proBNP takes place in the circulation and to evaluate the clearance rate of proBNP and proBNP-derived peptides...
  5. doi Immunodetection of glycosylated NT-proBNP circulating in human blood
    Karina R Seferian
    HyTest Ltd, Turku, Finland
    Clin Chem 54:866-73. 2008
    ..Recently it has been shown that proBNP is O-glycosylated in human blood. The goal of this study was to map sites on the NT-proBNP molecule that should be recognized by antibodies used in optimal NT-proBNP assays...
  6. doi Novel immunoassay for quantification of brain natriuretic peptide and its precursor in human blood
    Natalia N Tamm
    HyTest Ltd, Turku, Finland
    Clin Chem 54:1511-8. 2008
    ..The purpose of our study was to develop a sandwich immunoassay for the precise quantification of BNP and BNP precursor (proBNP) in human blood that is not susceptible to proteolysis...
  7. doi Measurement of B-type natriuretic peptide by two assays utilizing antibodies with different epitope specificity
    Natalia N Tamm
    HyTest Ltd, Intelligate, 6th Floor, Joukahaisenkatu 6, 20520 Turku, Finland
    Clin Biochem 44:257-9. 2011
    ..To compare plasma BNP values determined by a conventional-type and a novel-type of BNP assays...
  8. ncbi The brain natriuretic peptide (BNP) precursor is the major immunoreactive form of BNP in patients with heart failure
    Karina R Seferian
    HyTest Ltd, Turku, Finland
    Clin Chem 53:866-73. 2007
    ..It remains unclear which forms of these peptides circulate in blood and which forms are measured by assays for these natriuretic peptides...