Research Topics
| Stefan SadkiewiczSummaryCountry: Finland Publications
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Publications
Contemporary disease modifying antirheumatic drugs (DMARD) in patients with recent onset rheumatoid arthritis in a US private practice: methotrexate as the anchor drug in 90% and new DMARD in 30% of patientsTuulikki Sokka
Vanderbilt University, Nashville, Tennessee 37232, USA
J Rheumatol 29:2521-4. 2002....
A new disease activity index for rheumatoid arthritis: Mean Overall Index for Rheumatoid Arthritis (MOI-RA)Heidi Makinen
Jyvaskyla Central Hospital, Jyvaskyla, Finland
J Rheumatol 35:1522-7. 2008....
Quantitative assessment of rheumatoid arthritis in standard clinical care: turning clinical care into clinical scienceTuulikki Sokka
Arkisto Tutkijat, Jyvaskyla Central Hospital, 40620 Jyvaskyla, Finland
Best Pract Res Clin Rheumatol 21:653-61. 2007..Furthermore, routine data collection on consecutive patients facilitates the analysis of groups of patients, providing more information than can be obtained from randomized clinical trials...
Serum osteoprotegerin is increased and independently associated with coronary-artery atherosclerosis in patients with rheumatoid arthritisYu Asanuma
Saitama Medical University, Saitama, Japan
Atherosclerosis 195:e135-41. 2007..43-3.34), p<0.001]. In conclusion, OPG concentrations are increased in patients with RA and are associated with inflammation. In patients with long-standing disease, OPG is independently associated with coronary-artery calcification...
Decreased muscle strength and mobility of the neck in patients with rheumatoid arthritis and atlantoaxial disordersArja Hakkinen
Department of Physical Medicine and Rehabilitation, Jyvaskyla Central Hospital, Jyvaskyla, Finland
Arch Phys Med Rehabil 86:1603-8. 2005..To compare neck muscle strength and mobility of the cervical spine in rheumatoid arthritis (RA) patients with and without atlantoaxial (AA) disorders (anterior atlantoaxial subluxation [AAS], AA impaction)...
Similar clinical outcomes in rheumatoid arthritis with more versus less expensive treatment strategies. Observational data from two rheumatology clinicsTuulikki Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland
Clin Exp Rheumatol 31:409-14. 2013..Treatments aim at remission or at least low disease activity. Our objective was to study whether treatment target is reached and to what cost, in patients with RA in two Nordic rheumatology clinics...
Declining needs for total joint replacements for rheumatoid arthritisNasim A Khan
Arkisto Tutkijat, Jyvaskyla Central Hospital, 40620 Jyvaskyla, Finland
Arthritis Res Ther 13:130. 2011....
Utility of the Framingham risk score to predict the presence of coronary atherosclerosis in patients with rheumatoid arthritisCecilia P Chung
Department of Medicine, Vanderbilt University School of Medicine, 1161 21st Ave, Nashville, TN 37232, USA
Arthritis Res Ther 8:R186. 2006..15, 95% CI 1.02 to 1.29, P = 0.03). In conclusion, a higher Framingham risk score is independently associated with the presence of coronary calcification in patients with RA...
Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA studyAntonio Naranjo
Hospital de Gran Canaria Dr, Negrin, University of Las Palmas de Gran Canaria, Barranco de la Ballena s n 35011, Spain
Arthritis Res Ther 10:R30. 2008....
Remission as the treatment goal--the FIN-RACo trialT Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland
Clin Exp Rheumatol 24:S-74-6. 2006..The study showed that a third of patients with active early RA may achieve remission with a combination of methotrexate (MTX), sulfasalazine (SSZ), hydroxychloroquine (HCQ), and prednisolone...
Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA studyTuulikki Sokka
Jyvaskyla Central Hospital, Keskussairaalantie 19, 40620 Jyvaskyla, and Medcare Oy, Hämeentie 1, 44100 Aanekoski, Finland
Arthritis Res Ther 11:R7. 2009....
Stable occurrence of knee and hip total joint replacement in Central Finland between 1986 and 2003: an indication of improved long-term outcomes of rheumatoid arthritisTuulikki Sokka
Jyvaskyla Central Hospital, Arkisto Tutkijat, Jyväskylä 40620, Finland
Ann Rheum Dis 66:341-4. 2007..Total joint replacement (TJR) surgery is an important severe long-term outcome of rheumatoid arthritis, but relatively little is known about changes of its incidence in patients with rheumatoid arthritis over the past two decades...
Most people over age 50 in the general population do not meet ACR remission criteria or OMERACT minimal disease activity criteria for rheumatoid arthritisT Sokka
Jyvaskyla Central Hospital, 40620 Jyvaskyla, Finland
Rheumatology (Oxford) 46:1020-3. 2007....
QUEST-RA: quantitative clinical assessment of patients with rheumatoid arthritis seen in standard rheumatology care in 15 countriesTuulikki Sokka
Arkisto Tutkijat, Jyvaskyla Central Hospital, 40620 Jyvaskyla, Finland
Ann Rheum Dis 66:1491-6. 2007..To conduct a cross-sectional review of non-selected consecutive outpatients with rheumatoid arthritis (RA) as part of standard clinical care in 15 countries for an overview of the characteristics of patients with RA...
Assessment of quality of rheumatoid arthritis care requires joint count and/or patient questionnaire data not found in a usual medical record: examples from studies of premature mortality, changes in clinical status between 1985 and 2000, and a QUEST-RA gT Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland
Clin Exp Rheumatol 25:86-97. 2007....
Physical inactivity in patients with rheumatoid arthritis: data from twenty-one countries in a cross-sectional, international studyTuulikki Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland
Arthritis Rheum 59:42-50. 2008..We studied the prevalence of physical activity and associations with demographic and disease-related variables in patients with RA from 21 countries...
Drug management of early rheumatoid arthritis - 2008Tuulikki Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland
Best Pract Res Clin Rheumatol 23:93-102. 2009..We present a historical perspective for the treatment of early RA using early RA cohorts from Finland as an example. Finally, we discuss principles of contemporary treatment of early RA in 2008...
Erythrocyte sedimentation rate, C-reactive protein, or rheumatoid factor are normal at presentation in 35%-45% of patients with rheumatoid arthritis seen between 1980 and 2004: analyses from Finland and the United StatesTuulikki Sokka
Jyvaskyla Central Hospital, 40620 Jyvaskyla, Finland
J Rheumatol 36:1387-90. 2009..To analyze erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and rheumatoid factor (RF) tests in 2 databases of consecutive patients with rheumatoid arthritis (RA) over 25 years between 1980 and 2004, in Finland and the USA...
Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA databaseT Sokka
Jyvaskyla Central Hospital, 40620 Jyvaskyla, Finland
Ann Rheum Dis 68:1666-72. 2009..To analyse associations between the clinical status of patients with rheumatoid arthritis (RA) and the gross domestic product (GDP) of their resident country...
Conventional monotherapy compared to a "sawtooth" treatment strategy in the radiographic progression of rheumatoid arthritis over the first eight yearsT M Sokka
Department of Medicine, Jyvaskyla Central Hospital, Finland
Clin Exp Rheumatol 17:527-32. 1999..To describe the treatment with disease-modifying antirheumatic drugs (DMARDs) in two inception cohorts of rheumatoid arthritis (RA) patients and to compare their radiographic outcomes...
Healing of erosions in rheumatoid arthritisT Sokka
Department of Medicine, Jyvaskyla Central Hospital, Keskussiraalantie 19, FIN 40620 Jyväskylä, Finland
Ann Rheum Dis 59:647-9. 2000..Two such cases are described...
Radiographic scoring in rheumatoid arthritis: a short introduction to the methodsTuulikki Sokka
Jyvaskyla Central Hospital, 40620 Jyvaskyla, Finland
Bull NYU Hosp Jt Dis 66:166-8. 2008..The Sharp and the Larsen scoring methods were introduced in the 1970s. Modifications of these methods over time have resulted in contemporary scoring systems that are described herein...
Morning stiffness and other patient-reported outcomes of rheumatoid arthritis in clinical practiceT Sokka
Department of Medicine, Jyvaskyla Central Hospital, Jyvaskyla, Finland
Scand J Rheumatol Suppl 125:23-7. 2011..The results are then immediately available to the rheumatologists, to facilitate doctor-patient communication to improve the quality of patient care, leading to better patient outcomes...
Increases in use of methotrexate since the 1980sT Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland
Clin Exp Rheumatol 28:S13-20. 2010..The data show that (I) MTX is currently the most frequently used DMARD in RA, and (II) that this development has taken about 20 years to emerge...
How should rheumatoid arthritis disease activity be measured today and in the future in clinical care?Tuulikki Sokka
Jyvaskyla Central Hospital, 40620 Jyvaskyla, Finland
Rheum Dis Clin North Am 36:243-57. 2010..Challenges of the measures need to be recognized and hurdles identified that prevent quantitative monitoring in every-day clinical care concerning disease activity and beyond. These aspects are discussed in this article...
Long-term outcomes of rheumatoid arthritisTuulikki Sokka
Jyvaskyla Central Hospital, Jyväskylä 40620, Finland
Curr Opin Rheumatol 21:284-90. 2009..Rheumatoid arthritis (RA) is recognized as a disease with a natural history of severe long-term outcomes, which appear to be improving at this time, as reported from many clinics...
Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA studyTuulikki Sokka
Jyvaskyla Central Hospital, Keskussairaalantie 19, 40620 Jyvaskyla, Finland
Arthritis Res Ther 12:R42. 2010..Recent reports suggest that the use of biologic agents offers potential for reduced work disability rates, but the conclusions are based on surrogate disease activity measures derived from studies primarily from Western countries...
Treatment of rheumatoid arthritis: a global perspective on the use of antirheumatic drugsTuulikki Sokka
Arkisto Tutkijat, Jyvaskyla Central Hospital, Jyvaskyla, Finland
Mod Rheumatol 18:228-39. 2008....
Muscle strength, pain, and disease activity explain individual subdimensions of the Health Assessment Questionnaire disability index, especially in women with rheumatoid arthritisA Hakkinen
Department of Physical Medicine and Rehabilitation, Jyvaskyla Central Hospital, Finland
Ann Rheum Dis 65:30-4. 2006....
Remission and rheumatoid arthritis: data on patients receiving usual care in twenty-four countriesTuulikki Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland, and Medcare Oy, Aänekoski, Finland
Arthritis Rheum 58:2642-51. 2008..To compare the performance of different definitions of remission in a large multinational cross-sectional cohort of patients with rheumatoid arthritis (RA)...
Stability of the upper neck during isometric neck exercises in rheumatoid arthritis patients with atlantoaxial disordersA Hakkinen
Department of Physical Medicine and Rehabilitation, Jyvaskyla Central Hospital, Jyvaskyla, Finland
Scand J Rheumatol 37:343-7. 2008..To study the effect of isometric neck strength exercises on upper cervical stability in patients with rheumatoid arthritis (RA)...
Pain and joint mobility explain individual subdimensions of the health assessment questionnaire (HAQ) disability index in patients with rheumatoid arthritisA Hakkinen
Department of Physical Medicine and Rehabilitation, Jyvaskyla Central Hospital, 40620 Jyvaskyla, Finland
Ann Rheum Dis 64:59-63. 2005..To explore the associations between individual subdimensions of the health assessment questionnaire (HAQ) and clinical variables in patients with rheumatoid arthritis...
Definitions of remission for rheumatoid arthritis and review of selected clinical cohorts and randomised clinical trials for the rate of remissionH Makinen
Jyvaskyla Central Hospital, Jyvaskyla, Finland
Clin Exp Rheumatol 24:S-22-8. 2006..However, all available remission criteria may ignore important aspects of RA, including physical function and radiographic damage...
Ascendancy of weekly low-dose methotrexate in usual care of rheumatoid arthritis from 1980 to 2004 at two sites in Finland and the United StatesT Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland
Rheumatology (Oxford) 47:1543-7. 2008....
Similar prediction of mortality by the health assessment questionnaire in patients with rheumatoid arthritis and the general populationT Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland
Ann Rheum Dis 63:494-7. 2004..In patients with rheumatoid arthritis, the HAQ predicts mortality, work disability, and hip replacement surgery. It has been widely used in rheumatology, but population based data are rare...
Sustained maintenance of exercise induced muscle strength gains and normal bone mineral density in patients with early rheumatoid arthritis: a 5 year follow upA Hakkinen
Department of Physical Medicine and Rehabilitation, Jyvaskyla Central Hospital, Keskussairaalantie 19, FIN 40620 Jyväskylä, Finland
Ann Rheum Dis 63:910-6. 2004....
Is DAS28 an appropriate tool to assess remission in rheumatoid arthritis?H Makinen
Jyvaskyla Central Hospital, Keskussairaalantie 19, 40620 Jyvaskyla, Finland
Ann Rheum Dis 64:1410-3. 2005..To study which cut off point of DAS28 corresponds to fulfilment of the American Rheumatism Association (ARA) preliminary remission criteria, and clinical remission criteria in patients with rheumatoid arthritis (RA)...
Markers for work disability in rheumatoid arthritisT Sokka
Jyvaskyla Central Hospital, Department of Medicine, Finland
J Rheumatol 28:1718-22. 2001..Improved work disability outcomes in RA will require attention to social, economic, and political issues, and wider physician and public education concerning RA, in addition to improved medical management of disease...
Functional disability in rheumatoid arthritis patients compared with a community population in FinlandTuulikki Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland
Arthritis Rheum 48:59-63. 2003..To compare Health Assessment Questionnaire (HAQ) scores of patients with rheumatoid arthritis (RA) with HAQ scores from a sex- and age-adjusted population...
Radiographic progression is getting milder in patients with early rheumatoid arthritis. Results of 3 cohorts over 5 yearsTuulikki Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland
J Rheumatol 31:1073-82. 2004..We investigated the 5-year radiographic progression of 3 cohorts of patients with early RA enrolled in the 1980s and 1990s...
Changes in Health Assessment Questionnaire disability scores over five years in patients with rheumatoid arthritis compared with the general populationTuulikki Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland
Arthritis Rheum 54:3113-8. 2006..To analyze longitudinal data over 5 years for changes in Health Assessment Questionnaire (HAQ) scores in patients with rheumatoid arthritis (RA) and age- and sex-matched controls from the general population...
Mortality in rheumatoid arthritis: 2008 updateT Sokka
Department of Medicine, Jyvaskyla Central Hospital, Jyvaskyla, Finland
Clin Exp Rheumatol 26:S35-61. 2008..Functional and global measures as well as comorbidities generally are the most significant predictors of premature death...
Dynamic strength training in patients with early rheumatoid arthritis increases muscle strength but not bone mineral densityA Hakkinen
Department of Physical Therapy, Central Finland Health Care District, Jyvaskyla
J Rheumatol 26:1257-63. 1999..To assess the effects of 12 months' dynamic strength training on muscle strength and bone mineral density (BMD) at the lumbar spine and femoral neck in patients with early rheumatoid arthritis (RA)...
Sustained remission and reduced radiographic progression with combination disease modifying antirheumatic drugs in early rheumatoid arthritisHeidi Makinen
Jyvaskyla Central Hospital, Jyvaskyla, Finland
J Rheumatol 34:316-21. 2007..To study sustainability of remission and good treatment response, and the association of both with radiographic progression, in early rheumatoid arthritis (RA) in the Finnish Rheumatoid Arthritis Combination Therapy trial (FIN-RACo)...
A home-based two-year strength training period in early rheumatoid arthritis led to good long-term compliance: a five-year followupArja Hakkinen
Central Finland Health Care District, Jyvaskyla, Finland
Arthritis Rheum 51:56-62. 2004..To evaluate the impact of a 2-year home-based strength-training program on physical function in patients with early rheumatoid arthritis (RA) after a subsequent 3-year followup...
Self-report functioning according to the ICF model in elderly patients with rheumatoid arthritis and in population controls using the multidimensional health assessment questionnaireArja Hakkinen
Department of Physical Medicine and Rehabilitation, Jyvaskyla Central Hospital, 40620 Jyvaskyla, Finland
J Rheumatol 36:246-53. 2009....
Disease activity score 28 as an instrument to measure disease activity in patients with early rheumatoid arthritisHeidi Makinen
Jyvaskyla Central Hospital, Jyvaskyla, Finland
J Rheumatol 34:1987-91. 2007....
Distribution of radiation in synovectomy of the knee with 166Ho-FHMA using image fusionJuha Vuorela
Department of Nuclear Medicine, Central Finland Central Hospital, Jyvaskyla, Finland
Cancer Biother Radiopharm 20:333-7. 2005....
Frequency of remissions in early rheumatoid arthritis defined by 3 sets of criteria. a 5-year followup studyHeidi Makinen
Jyvaskyla Central Hospital, Jyvaskyla, Finland
J Rheumatol 32:796-800. 2005..To study the frequency of remission using 3 sets of criteria in patients with rheumatoid arthritis (RA) at 5 years after the diagnosis...
Effects of dynamic strength training on physical function, Valpar 9 work sample test, and working capacity in patients with recent-onset rheumatoid arthritisArja Hakkinen
Central Finland Health Care District, Jyvaskyla, Finland
Arthritis Rheum 49:71-7. 2003..To study the impact of 24 months of strength training on the physical function of patients with early rheumatoid arthritis (RA)...
Eligibility of patients in routine care for major clinical trials of anti-tumor necrosis factor alpha agents in rheumatoid arthritisTuulikki Sokka
, , Finland
Arthritis Rheum 48:313-8. 2003..Anti-TNFalpha therapy may be desirable in most patients with RA, but this possibility has not been studied formally. Criteria for inclusion in RA clinical trials might be modified for greater generalizability of results...
Erosions develop rarely in joints without clinically detectable inflammation in patients with early rheumatoid arthritisTuulikki Sokka
Jyvaskyla Central Hospital, Jyvaskyla, Finland
J Rheumatol 30:2580-4. 2003....
Joint counts to assess rheumatoid arthritis for clinical research and usual clinical care: advantages and limitationsTuulikki Sokka
Jyvaskyla Central Hospital, Jyvaskyla, and Medcare Oy, Aänekoski, Finland
Rheum Dis Clin North Am 35:713-22, v-vi. 2009....
Palindromic rheumatism: longterm outcomes of 60 patients diagnosed in 1967-84Essi Koskinen
Jyvaskyla Central Hospital, Jyvaskyla, Finland
J Rheumatol 36:1873-5. 2009..To study longterm outcomes of 60 patients with palindromic rheumatism (PR) diagnosed in 1967-1984...
Poor physical fitness and performance as predictors of mortality in normal populations and patients with rheumatic and other diseasesT Sokka
Department of Medicine, Jyvaskyla Central Hospital, Jyvaskyla, Finland
Clin Exp Rheumatol 26:S14-20. 2008..The data support recommendations for regular exercise in all individuals whether or not they have a disease, to promote health and longevity...
Conventional disease-modifying antirheumatic drugs in early arthritisTuulikki Sokka
Department of Rheumatology, , , Finland
Rheum Dis Clin North Am 31:729-44. 2005..Of patients with early RA, 20% to 30% do not improve enough with conventional treatments and should be identified at early phases to consider institution of biologic agents...
Most patients receiving routine care for rheumatoid arthritis in 2001 did not meet inclusion criteria for most recent clinical trials or american college of rheumatology criteria for remissionTuulikki Sokka
Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
J Rheumatol 30:1138-46. 2003....
Normative values for the Health Assessment Questionnaire disability index: benchmarking disability in the general populationEswar Krishnan
Stanford University, Palo Alto, California, USA
Arthritis Rheum 50:953-60. 2004..This study was undertaken to establish normative values for the HAQ DI in a general population and to analyze its correlates...
Patient questionnaires and formal education level as prospective predictors of mortality over 10 years in 97% of 1416 patients with rheumatoid arthritis from 15 United States private practicesTheodore Pincus
Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-4500, USA
J Rheumatol 31:229-34. 2004..This study shows that it is possible to account for more than 95% of patients over 10 years using mailed questionnaires to monitor patient status...
Smoking-gender interaction and risk for rheumatoid arthritisEswar Krishnan
Department of Medicine, Stanford University, Palo Alto, California, USA
Arthritis Res Ther 5:R158-62. 2003..We conclude that sex is a biologic effect modifier in the association between smoking and rheumatoid arthritis. The role of menopause in the etiology of rheumatoid arthritis merits further research...
Quantitative measures for assessing rheumatoid arthritis in clinical trials and clinical careTheodore Pincus
Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, 203 Oxford House, Box 5, Nashville, TN 37232-4500, USA
Best Pract Res Clin Rheumatol 17:753-81. 2003..The most simple and effective method of collecting important long-term data from patients in routine clinical care is through patient self-report questionnaires...
Early and extensive erosiveness in peripheral joints predicts atlantoaxial subluxations in patients with rheumatoid arthritisMarko Henrik Neva
Division of Orthopaedic and Trauma Surgery, Department of Surgery, Tampere University Hospital, Tampere, Finland
Arthritis Rheum 48:1808-13. 2003..e., vertical subluxation) in patients with rheumatoid arthritis (RA) who were treated early and continuously with disease-modifying antirheumatic drugs for 8-13 years...
Morning stiffness in patients with early rheumatoid arthritis is associated more strongly with functional disability than with joint swelling and erythrocyte sedimentation rateYusuf Yazici
Brooklyn Heights Arthritis Associates, Long Island College Hospital, Brooklyn, New York, USA
J Rheumatol 31:1723-6. 2004..To compare the level of morning stiffness in a cohort of patients with early rheumatoid arthritis (RA), assessed on a self-report questionnaire, to levels of patient self-report scores and clinical and laboratory variables...
Quantitative measures of rheumatic diseases for clinical research versus standard clinical care: differences, advantages and limitationsTheodore Pincus
NYU Hospital for Joint Diseases, New York, NY 10003, USA
Best Pract Res Clin Rheumatol 21:601-28. 2007..More attention to measures for use in standard care could improve care and outcomes for patients with rheumatic diseases...
Functional Health Assessment Questionnaire (HAQ) and Psychological HAQ Are Associated with and Predicted by Different Factors in Rheumatoid ArthritisSuzanne M M Verstappen
Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands
J Rheumatol 34:1837-40. 2007..To evaluate the association between clinical, demographic, and psychological factors and the functional Health Assessment Questionnaire (HAQ) and psychological HAQ (PSHAQ) in patients with rheumatoid arthritis (RA)...
Differences in clinical status measures in different ethnic/racial groups with early rheumatoid arthritis: implications for interpretation of clinical trial dataYusuf Yazici
New York University Hospital for Joint Diseases, New York, New York, USA
J Rheumatol 34:311-5. 2007..We compared patients with early rheumatoid arthritis (RA) of different ethnic/racial groups according to disease activity measures, to identify possible differences in patterns of severity of clinical status...
Patients seen for standard rheumatoid arthritis care have significantly better articular, radiographic, laboratory, and functional status in 2000 than in 1985Theodore Pincus
Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 4500, USA
Arthritis Rheum 52:1009-19. 2005..This study was undertaken to determine whether the clinical status of patients with rheumatoid arthritis (RA) has improved on average in recent years...
Prognosis of 5-year radiographic erosions of the wrist according to early, late, and persistent wrist swelling or tenderness in patients with early rheumatoid arthritisReijo Luukkainen
Satakunta Central Hospital, Rauma, Finland
J Rheumatol 34:50-3. 2007....
Assessment of pain in patients with rheumatic diseasesTuulikki Sokka
Vanderbilt University Rheumatology, 203 Oxford House, Nashville, TN 37232 4500, USA
Best Pract Res Clin Rheumatol 17:427-49. 2003....
Further development of a physical function scale on a MDHAQ [corrected] for standard care of patients with rheumatic diseasesTheodore Pincus
Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
J Rheumatol 32:1432-9. 2005..3-0.5 units lower than HAQ scores...
Increased coronary-artery atherosclerosis in rheumatoid arthritis: relationship to disease duration and cardiovascular risk factorsCecilia P Chung
Vanderbilt University School of Medicine, Nashville, Tennessee 37232-6602, USA
Arthritis Rheum 52:3045-53. 2005..CONCLUSION: The prevalence and severity of coronary calcification is increased in patients with established RA and is related, in part, to smoking and an increased erythrocyte sedimentation rate...
Survey nonresponse is associated with increased mortality in patients with rheumatoid arthritis and in a community populationMarkku Kauppi
Rheumatism Foundation Hospital, Heinola, Finland
J Rheumatol 32:807-10. 2005..The possible nonresponse bias should be kept in mind in the interpretation of the results of studies that are based on mail questionnaires only...
Quantitative measures to assess patients with rheumatic diseases: 2006 updateTheodore Pincus
Division of Rheumatology and Immunology, Vanderbilt University School of Medicine, 203 Oxford House, Box 5, Nashville, TN 37232-4500, USA
Rheum Dis Clin North Am 32:29-36. 2006
Prevalence of the metabolic syndrome is increased in rheumatoid arthritis and is associated with coronary atherosclerosisCecilia P Chung
Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 6602, USA
Atherosclerosis 196:756-63. 2008..In conclusion, patients with RA have a higher prevalence of the metabolic syndrome than control subjects. Inflammation-associated metabolic syndrome is a mechanism that may contribute to increased coronary-artery atherosclerosis in RA...
Improving outcomes in rheumatoid arthritis: what determines decisions to change ineffective therapy?Tuulikki Sokka
J Rheumatol 33:1213-5. 2006
Rheumatoid arthritis databasesTuulikki Sokka
Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, 203 Oxford House, Nashville, TN 37232 4500, USA
Rheum Dis Clin North Am 30:769-81, vi. 2004..This article describes selected computerized RA databases from the United States and Europe and focuses on their novel observations concerning long-term outcomes of RA...
Are excellent systematic reviews of clinical trials useful for patient care?Theodore Pincus
Department of Medicine, Division of Rheumatology, New York University Hospital for Joint Diseases, New York, NY 10003, USA
Nat Clin Pract Rheumatol 4:294-5. 2008
National databases and rheumatology research I: longitudinal databases in ScandinaviaTuulikki Sokka
Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, 203 Oxford House, Nashville, TN 37232 4500, USA
Rheum Dis Clin North Am 30:851-67, viii. 2004..The registers have long historical backgrounds, and are regulated strictly by law. This article describes features of the national databases and provides some examples of rheumatology research that use these databases...
Clinical trials in rheumatic diseases: designs and limitationsTheodore Pincus
Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
Rheum Dis Clin North Am 30:701-24, v-vi. 2004..Therefore, long-term databases are needed to supplement clinical trials in analyzing results of therapy for rheumatoid arthritis...
Inflammation-associated insulin resistance: differential effects in rheumatoid arthritis and systemic lupus erythematosus define potential mechanismsCecilia P Chung
Vanderbilt University School of Medicine, Nashville, Tennessee 37232 6602, USA
Arthritis Rheum 58:2105-12. 2008....
Quantitative measures and indices to assess rheumatoid arthritis in clinical trials and clinical careTheodore Pincus
Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, 203 Oxford House, Box 5, Nashville, TN 37232 4500, USA
Rheum Dis Clin North Am 30:725-51, vi. 2004..Therefore, the measures have been combined into pooled indices that can be applied to individual patients in clinical research and clinical care...
Increased augmentation index in rheumatoid arthritis and its relationship to coronary artery atherosclerosisIngrid Avalos
Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2681, USA
J Rheumatol 34:2388-94. 2007..We examined the hypothesis that augmentation index and pulse wave velocity are increased in RA, and are related to coronary artery atherosclerosis...
National databases and rheumatology research II: the National Health and Nutrition Examination SurveysTuulikki Sokka
Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University, 203 Oxford House, Nashville, TN 37232 4500, USA
Rheum Dis Clin North Am 30:869-78, viii. 2004..This article describes features of the surveys and provides examples of research on musculoskeletal disorders that used the survey data...
Can a Multi-Dimensional Health Assessment Questionnaire (MDHAQ) and Routine Assessment of Patient Index Data (RAPID) scores be informative in patients with all rheumatic diseases?Theodore Pincus
NYU Hospital for Joint Diseases, 301 East 17 Street, New York, NY 10003, USA
Best Pract Res Clin Rheumatol 21:733-53. 2007....
A three-page Standard Protocol to Evaluate Rheumatoid Arthritis (SPERA) for efficient capture of essential data from patients and health professionals in standard clinical care and clinical researchTheodore Pincus
NYU Hospital for Joint Diseases, 301 East 17 Street, New York, NY 10003, USA
Best Pract Res Clin Rheumatol 21:677-85. 2007..The SPERA is presented not as an optimal format but rather as an example of a possible approach to develop a common format for core clinical data to be collected in standard clinical care...
Are long-term very low doses of prednisone for patients with rheumatoid arthritis as helpful as high doses are harmful?Theodore Pincus
Ann Intern Med 136:76-8. 2002
