Ville Veckman

Summary

Affiliation: National Public Health Institute
Country: Finland

Publications

  1. ncbi request reprint Lactobacilli and streptococci induce inflammatory chemokine production in human macrophages that stimulates Th1 cell chemotaxis
    Ville Veckman
    Department of Microbiology, National Public Health Institute, Helsinki, Finland
    J Leukoc Biol 74:395-402. 2003
  2. ncbi request reprint Streptococcus pyogenes and Lactobacillus rhamnosus differentially induce maturation and production of Th1-type cytokines and chemokines in human monocyte-derived dendritic cells
    Ville Veckman
    Department of Microbiology, National Public Health Institute, Helsinki, Finland
    J Leukoc Biol 75:764-71. 2004
  3. ncbi request reprint Streptococcus pyogenes activates human plasmacytoid and myeloid dendritic cells
    Ville Veckman
    Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, FI 00300 Helsinki, Finland
    J Leukoc Biol 83:296-304. 2008
  4. ncbi request reprint TNF-alpha and IFN-alpha enhance influenza-A-virus-induced chemokine gene expression in human A549 lung epithelial cells
    Ville Veckman
    Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    Virology 345:96-104. 2006
  5. ncbi request reprint Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells
    Anne Lehtonen
    Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, FI 00300 Helsinki, Finland
    J Leukoc Biol 82:710-20. 2007
  6. ncbi request reprint Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells
    Taija E Pietila
    Department of Viral Diseases and Immunology, National Public Health Institute, Helsinki, Finland
    J Immunol 178:253-61. 2007
  7. pmc Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells
    Pamela Osterlund
    Department of Viral Diseases and Immunology, National Public Health Institute, Helsinki, Finland
    J Virol 79:9608-17. 2005
  8. pmc Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression
    Sampsa Matikainen
    Department of Viral Diseases and Immunology, National Public Health Institute, Helsinki, Finland
    J Virol 80:3515-22. 2006
  9. doi request reprint Live Lactobacillus rhamnosus and Streptococcus pyogenes differentially regulate Toll-like receptor (TLR) gene expression in human primary macrophages
    Minja Miettinen
    Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland
    J Leukoc Biol 84:1092-100. 2008
  10. ncbi request reprint Transcript profiles of dendritic cells of PLOSL patients link demyelinating CNS disorders with abnormalities in pathways of actin bundling and immune response
    Anna Kiialainen
    Department of Molecular Medicine, National Public Health Institute, Biomedicum, Haartmaninkatu 8, 00290, Helsinki, Finland
    J Mol Med (Berl) 85:971-83. 2007

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Lactobacilli and streptococci induce inflammatory chemokine production in human macrophages that stimulates Th1 cell chemotaxis
    Ville Veckman
    Department of Microbiology, National Public Health Institute, Helsinki, Finland
    J Leukoc Biol 74:395-402. 2003
    ..Furthermore, L. rhamnosus-induced Th1 chemokine production could in part explain the proposed antiallergenic properties of this bacterium...
  2. ncbi request reprint Streptococcus pyogenes and Lactobacillus rhamnosus differentially induce maturation and production of Th1-type cytokines and chemokines in human monocyte-derived dendritic cells
    Ville Veckman
    Department of Microbiology, National Public Health Institute, Helsinki, Finland
    J Leukoc Biol 75:764-71. 2004
    ..pyogenes induced a strong Th1-type response, stimulation with nonpathogenic L. rhamnosus resulted in development of semi-mature DCs characterized by moderate expression of costimulatory molecules and low cytokine production...
  3. ncbi request reprint Streptococcus pyogenes activates human plasmacytoid and myeloid dendritic cells
    Ville Veckman
    Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, FI 00300 Helsinki, Finland
    J Leukoc Biol 83:296-304. 2008
    ..Our results show that depending on the infecting microbe, the functions of PDCs and MDCs may be partially overlapping, suggesting a considerable flexibility of the human DC system...
  4. ncbi request reprint TNF-alpha and IFN-alpha enhance influenza-A-virus-induced chemokine gene expression in human A549 lung epithelial cells
    Ville Veckman
    Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    Virology 345:96-104. 2006
    ..Our results suggest that IFN-alpha and TNF-alpha have a significant role in priming epithelial cells for higher cytokine and chemokine production in influenza A virus infection...
  5. ncbi request reprint Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells
    Anne Lehtonen
    Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, FI 00300 Helsinki, Finland
    J Leukoc Biol 82:710-20. 2007
    ..Our results reveal significant differences in gene expression profiles between macrophages and DC, and these differences can partially explain the functional differences between these two important cell types...
  6. ncbi request reprint Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells
    Taija E Pietila
    Department of Viral Diseases and Immunology, National Public Health Institute, Helsinki, Finland
    J Immunol 178:253-61. 2007
    ..Our experiments reveal that expression of the CCL19 gene is regulated by a combined action of several members of the NF-kappaB, IRF, and STAT family transcription factors...
  7. pmc Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells
    Pamela Osterlund
    Department of Viral Diseases and Immunology, National Public Health Institute, Helsinki, Finland
    J Virol 79:9608-17. 2005
    ..Our results show that in human mDCs viruses can readily induce the expression of IL-28 and IL-29 genes whose gene products are likely to contribute to the host antiviral response...
  8. pmc Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression
    Sampsa Matikainen
    Department of Viral Diseases and Immunology, National Public Health Institute, Helsinki, Finland
    J Virol 80:3515-22. 2006
    ....
  9. doi request reprint Live Lactobacillus rhamnosus and Streptococcus pyogenes differentially regulate Toll-like receptor (TLR) gene expression in human primary macrophages
    Minja Miettinen
    Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland
    J Leukoc Biol 84:1092-100. 2008
    ..Our data suggest that macrophages can discriminate between probiotic and pathogenic bacteria by IFN-mediated TLR gene regulation...
  10. ncbi request reprint Transcript profiles of dendritic cells of PLOSL patients link demyelinating CNS disorders with abnormalities in pathways of actin bundling and immune response
    Anna Kiialainen
    Department of Molecular Medicine, National Public Health Institute, Biomedicum, Haartmaninkatu 8, 00290, Helsinki, Finland
    J Mol Med (Berl) 85:971-83. 2007
    ..The data underline the functional diversity of the molecules of the innate immune system and implies their significant contribution also in demyelinating CNS disorders, including those resulting in dementia...
  11. ncbi request reprint Differential expression of IFN regulatory factor 4 gene in human monocyte-derived dendritic cells and macrophages
    Anne Lehtonen
    Department of Viral Diseases and Immunology, National Public Health Institute, Helsinki, Finland
    J Immunol 175:6570-9. 2005
    ..Our results suggest that IRF4 is likely to play an important role in myeloid DC differentiation and gene regulatory functions...
  12. pmc Potentially probiotic bacteria induce efficient maturation but differential cytokine production in human monocyte-derived dendritic cells
    Sinikka Latvala
    Department of Viral Diseases and Immunology, National Public Health Institute, Mannerheimintie 166, Helsinki Finland
    World J Gastroenterol 14:5570-83; discussion 5581-2. 2008
    ..To analyze the ability of nine different potentially probiotic bacteria to induce maturation and cytokine production in human monocyte-derived dendritic cells (moDCs)...
  13. ncbi request reprint Cytokine and contact-dependent activation of natural killer cells by influenza A or Sendai virus-infected macrophages
    Jukka Sirén
    Department of Microbiology, National Public Health Institute, Helsinki, Finland
    J Gen Virol 85:2357-64. 2004
    ..In conclusion, these results show that virus-infected macrophages activate NK cells via cytokines and direct cellular interactions and further emphasize the role of IFN-alpha in the activation of innate immunity...
  14. ncbi request reprint Activation, cytokine production, and intracellular survival of bacteria in Salmonella-infected human monocyte-derived macrophages and dendritic cells
    Taija E Pietila
    Department of Viral Disease and Immunology, National Public Health Institute, Helsinki, Finland
    J Leukoc Biol 78:909-20. 2005
    ..Our results demonstrate that although Mphis and DCs share similar functions, they may have different roles during Salmonella infection as a result of differential production of certain chemokines and cytokines...
  15. ncbi request reprint IFN regulatory factor family members differentially regulate the expression of type III IFN (IFN-lambda) genes
    Pamela I Osterlund
    Department of Viral Diseases and Immunology, National Public Health Institute, Helsinki, Finland
    J Immunol 179:3434-42. 2007
    ....
  16. pmc Probiotic Leuconostoc mesenteroides ssp. cremoris and Streptococcus thermophilus induce IL-12 and IFN-gamma production
    Riina A Kekkonen
    University of Helsinki, Institute of Biomedicine, Pharmacology, Helsinki 00014, Finland
    World J Gastroenterol 14:1192-203. 2008
    ....