Research Topics
Species | M MiettinenSummaryAffiliation: National Public Health Institute Country: Finland Publications
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Detail Information
Publications
Lactobacilli and Streptococci activate NF-kappa B and STAT signaling pathways in human macrophagesM Miettinen
Department of Virology, National Public Health Institute, Helsinki, Finland
J Immunol 164:3733-40. 2000....
Lactobacilli and streptococci induce interleukin-12 (IL-12), IL-18, and gamma interferon production in human peripheral blood mononuclear cellsM Miettinen
Department of Virology, National Public Health Institute, 00300 Helsinki, Finland
Infect Immun 66:6058-62. 1998..IL-10 and IL-4 production was induced weakly and not at all, respectively. Our data show that nonpathogenic lactobacilli and pathogenic streptococci can induce Th1 type cytokines IL-12, IL-18, and IFN-gamma in human PBMC...
IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12S Matikainen
Department of Microbiology, National Public Health Institute, Helsinki, Finland
Eur J Immunol 31:2236-45. 2001..Our results demonstrate that IFN-alpha and IL-18 are important innate cytokines in inducing NK cell IFN-gamma production...
Production of human tumor necrosis factor alpha, interleukin-6, and interleukin-10 is induced by lactic acid bacteriaM Miettinen
National Public Health Institute, Helsinki, Finland
Infect Immun 64:5403-5. 1996..Our results suggest that lactic acid bacteria can stimulate nonspecific immunity...
Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell responseE Giacomini
Laboratories of. Immunology and Bacteriology and Medical Mycology, , Rome, Italy. Department of Virology, National Public Health Institute, Helsinki, Finland
J Immunol 166:7033-41. 2001....
IFNs activate toll-like receptor gene expression in viral infectionsM Miettinen
Department of Microbiology, National Public Health Institute, Helsinki, Finland
Genes Immun 2:349-55. 2001..IFN-gamma enhanced the expression of TLR1 and TLR2 mRNA in macrophages, and TLR3 in epithelial and endothelial cells. The data suggests a novel role for IFNs in the activation of innate immunity...
