Research Topics
| Paul KnektSummaryAffiliation: National Public Health Institute Country: Finland Publications
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Detail Information
Publications
Risk of colorectal and other gastro-intestinal cancers after exposure to nitrate, nitrite and N-nitroso compounds: a follow-up studyP Knekt
National Public Health Institute, Helsinki, Finland
Int J Cancer 80:852-6. 1999..Our results are in line with the idea that N-nitroso compounds can induce colorectal cancer in humans...
Hyperhomocystinemia: a risk factor or a consequence of coronary heart disease?P Knekt
National Public Health, Mannerheimintie 166, 00300 Helsinki, Finland
Arch Intern Med 161:1589-94. 2001..Mild hyperhomocystinemia has been suggested as an indicator of an increased risk of cardiovascular disease...
Homocysteine and major coronary events: a prospective population study amongst womenP Knekt
Department of Nutrition and Department of Health and Disability, National Public Health Institute, Helsinki, Finland
J Intern Med 249:461-5. 2001..To study serum homocysteine concentration for its prediction of major coronary heart disease events amongst women...
Quercetin intake and the incidence of cerebrovascular diseaseP Knekt
National Public Health Institute, Helsinki, Finland
Eur J Clin Nutr 54:415-7. 2000..To study the relation between intake of the antioxidant flavonoid quercetin and subsequent incidence of cerebrovascular disease (CVA)...
Randomized trial on the effectiveness of long-and short-term psychodynamic psychotherapy and solution-focused therapy on psychiatric symptoms during a 3-year follow-upP Knekt
Social Insurance Institution, Helsinki, Finland
Psychol Med 38:689-703. 2008..The present trial compares the effectiveness of one long-term therapy and two short-term therapies in the treatment of mood and anxiety disorders...
Flavonoid intake and risk of chronic diseasesPaul Knekt
National Public Health Institute, Helsinki, Finland
Am J Clin Nutr 76:560-8. 2002..Flavonoids are effective antioxidants and may protect against several chronic diseases...
Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohortsPaul Knekt
National Public Health Institute, Helsinki, Finland
Am J Clin Nutr 80:1508-20. 2004..Epidemiologic studies have suggested a lower risk of coronary heart disease (CHD) at higher intakes of fruit, vegetables, and whole grain. Whether this association is due to antioxidant vitamins or some other factors remains unclear...
Effectiveness of short-term and long-term psychotherapy on work ability and functional capacity--a randomized clinical trial on depressive and anxiety disordersPaul Knekt
Social Insurance Institution, Helsinki, Finland
J Affect Disord 107:95-106. 2008..Insufficient evidence exists about the effect of different therapies on work ability for patients with psychiatric disorders. The present study compares improvements in work ability in two short-term therapies and one long-term therapy...
Serum vitamin D and subsequent occurrence of type 2 diabetesPaul Knekt
National Public Health Institute, Department of Health and Functional Capacity, Mannerheimintie 166, 00300 Helsinki, Finland
Epidemiology 19:666-71. 2008..Although the epidemiologic evidence is scarce, 2 recent studies have suggested an association. The present study investigated the relation of serum vitamin D with type 2 diabetes incidence using pooled data from these 2 cohorts...
Helicobacter pylori IgA and IgG antibodies, serum pepsinogen I and the risk of gastric cancer: changes in the risk with extended follow-up periodPaul Knekt
National Public Health Institute, Helsinki, Finland
Int J Cancer 119:702-5. 2006....
Fish consumption and the incidence of cerebrovascular diseaseJukka Montonen
Department of Health and Functional Capacity, National Public Health Institute, Mannerheimintie 166, FIN 00300, Helsinki, Finland
Br J Nutr 102:750-6. 2009..The relationship between fish consumption and stroke risk is not straightforward. How the fish is prepared for consumption may play an important role, affecting the association...
Dietary antioxidant intake and risk of type 2 diabetesJukka Montonen
National Public Health Institute, Department of Health and Functional Capacity, Helsinki, Finland
Diabetes Care 27:362-6. 2004..The intake of antioxidants was studied for its ability to predict type 2 diabetes...
Vitamin D status and the risk of lung cancer: a cohort study in FinlandAnnamari Kilkkinen
Department of Health and Functional Capacity, National Public Health Institute, Mannerheimintie 166, FI 00300 Helsinki, Finland
Cancer Epidemiol Biomarkers Prev 17:3274-8. 2008....
Secular changes in disability among middle-aged and elderly Finns with and without coronary heart disease from 1978-1980 to 2000-2001Anna Kattainen
National Public Health Institute, Department of Health and Functional Capacity, Helsinki, Finland
Ann Epidemiol 14:479-85. 2004..To examine time trends in the prevalence of coronary heart disease (CHD) and disability...
The relative importance of modifiable potential risk factors of type 2 diabetes: a meta-analysis of two cohortsMaarit A Laaksonen
National Institute for Health and Welfare, Helsinki, Finland
Eur J Epidemiol 25:115-24. 2010..01). In conclusion, modification of lifestyle factors apparently reduces type 2 diabetes risk, especially in persons with normal blood pressure...
Dietary patterns and the incidence of type 2 diabetesJukka Montonen
National Public Health Institute, Helsinki, Finland
Am J Epidemiol 161:219-27. 2005..In light of these results, it appears conceivable that the risk of developing type 2 diabetes can be reduced by changing dietary patterns...
Long-term results of surgery for lumbar spinal stenosis: a randomised controlled trialPär Slätis
ORTON Orthopaedic Hospital, Invalid Foundation, Helsinki, Finland
Eur Spine J 20:1174-81. 2011..Walking ability did not differ between the treatment groups at any time. Decompressive surgery of LSS provided modest but consistent improvement in functional ability, surpassing that obtained after non-operative measures...
Serum 25-hydroxyvitamin D concentration and subsequent risk of type 2 diabetesCatharina Mattila
National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland
Diabetes Care 30:2569-70. 2007
Plant foods and the risk of cerebrovascular diseases: a potential protection of fruit consumptionAnna Mizrahi
National Institute for Health and Welfare, Helsinki, Finland
Br J Nutr 102:1075-83. 2009..67; 95 % CI 0.49, 0.92) and intracerebral haemorrhage (RR 0.49; 95 % CI 0.25, 0.98). In conclusion, the consumption of fruits, especially citrus, and cruciferous vegetables may protect against cerebrovascular diseases...
Vitamin D status and the risk of cardiovascular disease deathAnnamari Kilkkinen
National Institute for Health and Welfare, Helsinki, Finland
Am J Epidemiol 170:1032-9. 2009..These findings need to be replicated in other populations. To demonstrate a causal link between vitamin D and CVD, randomized controlled trials are required...
Vertebral fracture and cause-specific mortality: a prospective population study of 3,210 men and 3,730 women with 30 years of follow-upVille Puisto
National Institute for Health and Welfare, Mannerheimintie 166, 00271 Helsinki, Finland
Eur Spine J 20:2181-6. 2011..Vertebral fractures predict mortality, but little is known about their associations with the causes of death. We studied vertebral fractures for prediction of cause-specific mortality...
Nordic biological specimen banks as basis for studies of cancer causes and control--more than 2 million sample donors, 25 million person years and 100,000 prospective cancersEero Pukkala
Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland
Acta Oncol 46:286-307. 2007..The present paper summarizes optimal study designs of biobank-based studies of cancer...
Quasi-experimental study on the effectiveness of psychoanalysis, long-term and short-term psychotherapy on psychiatric symptoms, work ability and functional capacity during a 5-year follow-upPaul Knekt
Social Insurance Institution, Helsinki, Finland
J Affect Disord 132:37-47. 2011..Psychotherapy is apparently an insufficient treatment for some patients with mood or anxiety disorder. In this study the effectiveness of short-term and long-term psychotherapies was compared with that of psychoanalysis...
Obesity and unhealthy life-years in adult Finns: an empirical approachTommy L S Visscher
Department of Health and Disability, National Public Health Institute, Helsinki, Finland
Arch Intern Med 164:1413-20. 2004..Obese individuals are thus expected to have more unhealthy life-years than normal-weight persons. The objective of the present study was to quantify the number of excess unhealthy life-years in obese individuals...
Gastric cancers in Finnish patients after cure of Helicobacter pylori infection: A cohort studyTimo U Kosunen
Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Helsinki, Finland
Int J Cancer 128:433-9. 2011..To conclude, cured H. pylori infection led to a significantly decreased incidence of gastric cancers from the sixth follow-up year. Advanced atrophic gastritis would be a plausible contributor to the elevated SIR in elderly Hp- patients...
Consumption of sweetened beverages and intakes of fructose and glucose predict type 2 diabetes occurrenceJukka Montonen
National Public Health Institute, Helsinki FIN, Finland
J Nutr 137:1447-54. 2007..43; P < 0.001) for sweetened berry juice and 1.67 (95% [CI] = 0.98, 2.87; P = 0.01) for soft drinks. Our findings support the view that higher intake of fructose and glucose and sweetened beverages may increase type 2 diabetes risk...
Serum vitamin D and the risk of Parkinson diseasePaul Knekt
National Institute for Health and Welfare, Helsinki, Finland
Arch Neurol 67:808-11. 2010..To investigate whether serum vitamin D level predicts the risk of Parkinson disease...
Whole-grain and fiber intake and the incidence of type 2 diabetesJukka Montonen
National Public Health Institute, Helsinki, Finland
Am J Clin Nutr 77:622-9. 2003..Epidemiologic evidence of a preventive effect of whole grain against type 2 diabetes is mainly based on data from women. Information specific to men and women is needed...
Estimation of the population attributable fraction for mortality in a cohort study using a piecewise constant hazards modelMaarit A Laaksonen
National Institute for Health and Welfare, Helsinki, Finland
Am J Epidemiol 171:837-47. 2010..Cary, North Carolina) to estimate the mortality attributable to some common risk factors...
Fat free mass and obesity in relation to educational levelElina Seppänen-Nuijten
National Institute for Health and Welfare, Mannerheimintie 166, 00300 Helsinki, Finland
BMC Public Health 9:448. 2009....
Suitability for Psychotherapy Scale (SPS) and its reliability, validity, and predictionMaarit A Laaksonen
National Institute for Health and Welfare, Helsinki, Finland
Br J Clin Psychol 51:351-75. 2012..To present an interview-based 7-item Suitability for Psychotherapy Scale (SPS) created to evaluate suitability for short- and long-term therapy, and to assess its reliability, validity, and prediction...
The effectiveness of solution-focused therapy and short- and long-term psychodynamic psychotherapy on self-concept during a 3-year follow-upOlavi Lindfors
National Institute for Health and Welfare, Helsinki, Finland
J Nerv Ment Dis 200:946-53. 2012..Long duration and psychodynamic orientation of therapy may be beneficial for self-concept improvement...
Antibiotic use predicts an increased risk of cancerAnnamari Kilkkinen
Department of Health and Functional Capacity, National Public Health Institute, Helsinki, Finland
Int J Cancer 123:2152-5. 2008..In conclusion, antibiotic use predicts an increased risk of cancer. Because of the design of our study the possibility of residual confounding cannot be excluded and further studies are required to confirm the results...
Mapping geographical variation in obesity in FinlandMarjaana Lahti-Koski
Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
Eur J Public Health 18:637-43. 2008..The geographical pattern of mean anthropometric values and obesity prevalence were studied applying a Bayesian hierarchical approach and Geographical Information Systems...
Mortality in the presence of a vertebral fracture, scoliosis, or Scheuermann's disease in the thoracic spineVille Puisto
National Public Health Institute and the Hospital for Children and Adolescents, Helsinki, Finland
Ann Epidemiol 18:595-601. 2008..Vertebral fractures and scoliosis, unlike Scheuermann's disease, have been associated with increased mortality. Total and cause-specific mortalities of these spinal deformities were studied to produce epidemiologic knowledge...
The cost-effectiveness of short-term psychodynamic psychotherapy and solution-focused therapy in the treatment of depressive and anxiety disorders during a one-year follow-upTimo Maljanen
Social Insurance Institution, PO Box 450, 00101 Helsinki, Finland
J Ment Health Policy Econ 15:13-23. 2012..However, the number of randomized trials where psychological treatments are compared with each other and where economic aspects, too, are taken into account is still relatively small...
Use of auxiliary psychiatric treatment during a 5-year follow-up among patients receiving short- or long-term psychotherapyPaul Knekt
National Institute for Health and Welfare, Helsinki, Finland
J Affect Disord 135:221-30. 2011..This study considers changes in the need for auxiliary psychiatric treatment after starting short- and long-term psychotherapy and psychoanalysis...
Disability predicted mortality in men but not women with coronary heart diseaseAnna Kattainen
Department of Health and Functional Capacity, National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
J Clin Epidemiol 57:513-21. 2004..Disability increases mortality in patients with myocardial infarction in acute clinical settings, but the impact of disability on mortality in persons with coronary heart disease (CHD) at the population level is largely unknown...
Impact of cardiovascular diseases on activity limitations and need for help among older personsAnna Kattainen
Department of Health and Functional Capacity, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland
J Clin Epidemiol 57:82-8. 2004..The aim of this study was to estimate the importance of specific chronic cardiovascular diseases (CVDs) as determinants of disability...
Serum fatty acids and breast cancer incidenceHarri Rissanen
National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland
Nutr Cancer 45:168-75. 2003..The present study suggests that higher serum proportions of the n-6 PUFA linoleic acid and lower proportions of the MUFA trans-11-18:1 fatty acid predict a reduced incidence of breast cancer...
Therapists' professional and personal characteristics as predictors of outcome in short- and long-term psychotherapyErkki Heinonen
National Institute for Health and Welfare, Helsinki, Finland
J Affect Disord 138:301-12. 2012..Although psychotherapists differ in their effectiveness, virtually no comparative research exists on the therapist characteristics beneficial to short- or long-term therapy...
Validity of a food frequency questionnaire varied by age and body mass indexLaura Paalanen
Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
J Clin Epidemiol 59:994-1001. 2006..The validity of food frequency questionnaires (FFQs) in measuring food consumption and nutrient intake has to be assessed. The objective of this study was to assess the validity of a 128-item FFQ in specific subgroups of Finnish adults...
Secular changes in prevalence of cardiovascular diseases in elderly FinnsAnna Kattainen
National Public Health Institute, Department of Health and Functional Capacity, Helsinki, Finland
Scand J Public Health 30:274-80. 2002..The purpose of the present study was to examine changes with time in the prevalence of cardiovascular diseases (CVD) in Finns 65 to 74 years of age...
Vitamin D status is associated with sociodemographic factors, lifestyle and metabolic healthTuija Jääskeläinen
National Institute for Health and Welfare, Helsinki, Finland
Eur J Nutr 52:513-25. 2013..The aim of this study was to investigate the associations between serum 25(OH)D concentration and sociodemographic, lifestyle and metabolic health-related factors...
Dextrocardia and coronal alignment of thoracic curve: a population studyKaj Tallroth
ORTON Research Institute, Invalid Foundation, Helsinki, Finland
Eur Spine J 18:1941-5. 2009..We assume that the effect of the repetitive pulsatile pressure of the descending thoracic aorta, and the mass effect of the heart may cause the direction of the convexity to develop opposite to the side of the aortic arch...
Sociodemographic and socioeconomic differences in sleep duration and insomnia-related symptoms in Finnish adultsTea Lallukka
Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki, Finland
BMC Public Health 12:565. 2012..The aim of this study was to examine the associations of sociodemographic and socioeconomic factors with sleep duration and insomnia-related symptoms across life course...
Sagittal abdominal diameter as a new predictor for incident diabetesPia Pajunen
Corresponding author Harri Rissanen
Diabetes Care 36:283-8. 2013..88 (2.81-34.7). The corresponding population-attributable fraction estimate was 84% (49-95). CONCLUSIONS The combination of SAD and BMI measurements yields a new predictor of diabetes incidence...
Randomized trial on the effectiveness of long- and short-term psychotherapy on psychiatric symptoms and working ability during a 5-year follow-upPaul Knekt
National Institute for Health and Welfare, Helsinki, Finland
Nord J Psychiatry 67:59-68. 2013..The information on whether long-term psychotherapy is superior in comparison with short-term therapies during a long time-perspective in the treatment of mood and anxiety disorder is incomplete...
A "screen-and-treat" approach for Helicobacter pylori infection: a population-based study in Vammala, FinlandAnniina Salomaa-Rasanen
Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, Helsinki, Finland
Helicobacter 15:28-37. 2010..pylori"screen-treat-retest-and-retreat" program for all young adults at primary health care in Vammala, Finland after a pilot study in 1994 including 504 subjects aged 15-75...
Pretreatment clinical and psychosocial predictors of remission from depression after short-term psychodynamic psychotherapy and solution-focused therapy: a 1-year follow-up studyMauri Marttunen
Biomedicum Helsinki, Helsinki, Finland
Psychother Res 18:191-9. 2008..06 and 0.22 (95% confidence intervals = 0.01-0.35 and 0.05-0.97), respectively. In conclusion, several background factors, especially sense of coherence, predict remission...
Self-administered questionnaire is a reliable measure of coffee consumptionKatri Sääksjärvi
National Institute for Health and Welfare, Helsinki, Finland
J Epidemiol 20:363-9. 2010..The objective of this study was to assess the agreement and repeatability of 2 methods of measuring habitual coffee consumption, and to examine their homogeneity with respect to socioeconomic and lifestyle factors...
Depression and smoking cessation: the role of motivation and self-efficacyA Haukkala
National Public Health Institute, Department of Epidemiology and Health Promotion, Helsinki, Finland
Addict Behav 25:311-6. 2000..Our results suggest that depression is related to lower smoking cessation self-efficacy while smokers with higher depression scores seem to be more motivated to quit smoking...
Heart rate and mortalityA Reunanen
National Public Health Institute, Helsinki, Central Military Hospital, Helsinki, Finland
J Intern Med 247:231-9. 2000..Increased heart rate has also been linked to causes of death other than cardiovascular. To clarify the role of heart rate as a predictor of death we studied its predictive value in a large population study...
Coffee consumption, rheumatoid factor, and the risk of rheumatoid arthritisM Heliovaara
National Public Health Institute, Helsinki, Finland
Ann Rheum Dis 59:631-5. 2000..No attention, however, has been paid to coffee consumption as a risk determinant, though it is a shared covariate of the alleged risk factors...
Twenty-year changes in the prevalence of obesity among Finnish adultsM Lahti-Koski
National Institute for Health and Welfare THL, Helsinki University Hospital, Helsinki, Finland
Obes Rev 11:171-6. 2010..A comprehensive public health strategy targeting the whole population and especially those with low education is urgently needed to halt the obesity epidemic...
Serum ceruloplasmin and the risk of cancer in FinlandP Knekt
Social Insurance Institution, Helsinki, Finland
Br J Cancer 65:292-6. 1992..The most likely explanation of the present results thus is that high serum ceruloplasmin levels in lung cancer are mainly due to occult cancer...
A case study in comparing therapies involving informative drop-out, non-ignorable non-compliance and repeated measurementsT Härkänen
National Public Health Institute, Helsinki, Finland
Stat Med 24:3773-87. 2005..A Bayesian hierarchical as-treated model, which uses random-effects-based selection models to account for non-ignorable missing data and non-compliance, was compared with different mixed effects models...
Food consumption and the incidence of type II diabetes mellitusJ Montonen
National Public Health Institute, Helsinki, Finland
Eur J Clin Nutr 59:441-8. 2005..The consumption of different foods was studied for their ability to predict type II diabetes mellitus...
Concurrent validity of the Quality of Object Relations Scale (QORS) in relation to proxy assessment of the theoretical scale constituentsOlavi Lindfors
National Institute for Health and Welfare, Helsinki, Finland
Psychopathology 46:111-9. 2013..Our aim was to study the concurrent validity of the QORS...
Time trends in incidence and prevalence of human papillomavirus type 6, 11 and 16 infections in FinlandPäivi Laukkanen
National Public Health Institute, Helsinki and Oulu, Mannerheimintie 166, 00300 Helsinki, Finland
J Gen Virol 84:2105-9. 2003..Epidemic spread of the oncogenic HPV-16, but not the non-oncogenic HPV-types, throughout the 1980s and 1990s preceded an increase in the incidence of cervical carcinoma in fertile-aged Finnish women...
Prospective study of coffee consumption and risk of Parkinson's diseaseK Sääksjärvi
National Public Health Institute, Mannerheimintie 166, Helsinki, Finland
Eur J Clin Nutr 62:908-15. 2008..To examine the prediction of coffee consumption on the incidence of Parkinson's disease...
Low back pain and subsequent cardiovascular mortalityM Heliovaara
Social Insurance Institution, Helsinki, Finland
Spine (Phila Pa 1976) 20:2109-11. 1995..This was a prospective cohort study based on data of the Mini-Finland Health Examination Survey collected between 1978 and 1980, with follow-up until the end of 1991...
Changes in lifestyle for psychiatric patients three years after the start of short- and long-term psychodynamic psychotherapy and solution-focused therapyP Knekt
Social Insurance Institution, P O Box 450, 00101 Helsinki, Finland
Eur Psychiatry 25:1-7. 2010..We studied whether psychotherapy brings along changes in lifestyle and whether these changes differ between short-term and long-term psychodynamic psychotherapy (SPP and LPP) and solution-focused therapy (SFT)...
Smoking history and serum cotinine and thiocyanate concentrations as determinants of rheumatoid factor in non-rheumatoid subjectsT Korpilähde
National Public Health Institute, Helsinki, Finland
Rheumatology (Oxford) 43:1424-8. 2004..Smoking is associated with false-positive rheumatoid factor (RF). We explored the dose-response relationship of this association, using smoking history and serum cotinine and thiocyanate concentrations as measures of tobacco exposure...
Determinants of sciatica and low-back painM Heliovaara
Research Institute for Social Security, Social Insurance Institution, Helsinki, Finland
Spine (Phila Pa 1976) 16:608-14. 1991..4; 95% CI, 0.3-0.8). Many factors, independent of each other, determine the occurrence of chronic low-back syndromes. The determinants of sciatica and LBP are different to some extent...
Smoking and risk of colorectal cancerP Knekt
National Public Health Institute, Helsinki, Finland
Br J Cancer 78:136-9. 1998..To clarify the role of smoking in colorectal cancer development, further cohort studies are needed with long follow-up periods and allowing for control of dietary and other potential confounding factors...
Nationwide registry-based analysis of cancer clustering detects strong familial occurrence of Kaposi sarcomaEevi Kaasinen
Genome Scale Biology Research Program, and Department of Medical Genetics, Faculty of Medicine, University of Helsinki, Helsinki, Finland
PLoS ONE 8:e55209. 2013..Further work with high-throughput methods should elucidate the molecular basis of the potentially novel predisposition conditions found in this study...
Association between the Rorschach Ego Impairment Index and the Level of Personality Organization interview assessment in depressive and anxiety disorder patientsHarri Valkonen
Biomedicum Helsinki, Helsinki, Finland
Psychiatry Res 200:849-56. 2012..More research on the incremental benefits of the measures is needed in clinical populations, covering non-severe and complex psychopathology...
Surgical or nonoperative treatment for lumbar spinal stenosis? A randomized controlled trialAntti Malmivaara
Finnish Office for Health Technology Assessment, National Research and Development Center, FinOHTA Stakes, Helsinki, Finland
Spine (Phila Pa 1976) 32:1-8. 2007..A randomized controlled trial...
Does antibacterial treatment for urinary tract infection contribute to the risk of breast cancer?P Knekt
National Public Health Institute, Helsinki, Finland
Br J Cancer 82:1107-10. 2000..The results are, however, still inconclusive and the hypothesis needs to be tested by other studies...
Intake of dairy products and the risk of breast cancerP Knekt
National Public Health Insitute, Helsinki, Finland
Br J Cancer 73:687-91. 1996..Our data suggest that there is a protective effect, dietary or habitual, associated with consumption of milk that overwhelms the associations between different other factors and risk of breast cancer...
Validity of the prostate specific antigen test for prostate cancer screening: followup study with a bank of 21,000 sera in FinlandM Hakama
Department of Public Health, Helsinki University, Tampere University School of Public Health, Finnish Cancer Registry, University Hospital of Helsinki, The National Public Health Institute, Helsinki, Finland
J Urol 166:2189-91; discussion 2191-2. 2001..5 microg./l. CONCLUSIONS: PSA is a valid screening test for prostate cancer, which compares favorably with mammography for breast cancer. However, until an effect on mortality has been shown, routine screening cannot be recommended...
Enterovirus, mycoplasma and other infections as predictors for myocardial infarctionA Reunanen
Department of Health and Functional Capacity, National Public Health Institute, Helsinki, Finland
J Intern Med 252:421-9. 2002..To study antibodies against five infectious agents for their prediction of major coronary events in men with and without evidence of coronary heart disease at baseline...
IgA antibodies in persisting Helicobacter pylori infection in Finnish adultsA Salomaa-Rasanen
Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland
Clin Microbiol Infect 12:236-40. 2006..0241), respectively, whereas the median IgG levels did not change significantly in either series. During H. pylori infection, an increase in specific IgA was reflected by the increase in the number of responders and by the rise in titres...
Intake of fish and long-chain n-3 fatty acids and the risk of coronary heart mortality in men and womenRitva Järvinen
Department of Clinical Nutrition, University of Kuopio, PL 1627, 70211 Kuopio, Finland
Br J Nutr 95:824-9. 2006..In conclusion, our results for women are in line with the suggested protective effect of fish consumption against CHD but a similar association was not, however, found in men...
No serological evidence of association between prostate cancer and infection with herpes simplex virus type 2 or human herpesvirus type 8: a nested case-control studyZoltan Korodi
Department of Medical Microbiology, Lund University, University Hospital, Malmo, Sweden
J Infect Dis 191:2008-11. 2005..Neither HSV-2 infection (odds ratio [OR], 0.93 [95% confidence interval {CI}, 0.44-1.96]) nor HHV-8 infection (OR, 0.74 [95% CI, 0.19-2.88]) was associated with prostate cancer...
Schizophrenia, neuroleptic medication and mortalityMatti Joukamaa
Department of Social Psychiatry, Tampere School of Public Health, University of Tampere, FIN 33014, Finland
Br J Psychiatry 188:122-7. 2006..There is an excess of death from natural causes among people with schizophrenia...
Association of Helicobacter pylori IgA antibodies with the risk of peptic ulcer disease and gastric cancerTimo U Kosunen
Department of Bacteriology and Immunology, University of Helsinki, PO Box 21, FIN 00014 Helsinki, Finland
World J Gastroenterol 11:6871-4. 2005..To compare the prevalence of Helicobacter pylori (H pylori) IgG and IgA antibodies between adult subjects, with defined gastric diseases, non-defined gastric disorders and those representing the population...
Does good trunk extensor performance protect against back-related work disability?Aaro Rissanen
Helsinki City Health Department, Finland
J Rehabil Med 34:62-6. 2002..28 (95% confidence interval, 0.09-0.94). Our study suggests that good dynamic trunk extension performance may protect against back-related permanent work disability...
Antibodies to periodontal pathogens and stroke riskPirkko J Pussinen
Institute of Dentistry, University of Helsinki, P O Box 63 Haartmaninkatu 8, FIN 00014 Helsinki, Finland
Stroke 35:2020-3. 2004..Therefore, the aim of the study was to investigate whether elevated levels of serum antibodies to major periodontal pathogens predict stroke in a case-control study...
Dietary fiber and risk of coronary heart disease: a pooled analysis of cohort studiesMark A Pereira
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN55454, USA
Arch Intern Med 164:370-6. 2004..The purpose of this study was to conduct a pooled analysis of dietary fiber and its subtypes and risk of coronary heart disease...
Blood biochemistry and the risk of cancerMatti Hakama
University of Tampere School of Public Health, Finland
Acta Oncol 43:667-74. 2004..They are, furthermore, consistent with the hypothesis that pooling of biochemical samples affects the levels of the substances and may affect the conclusions of epidemiological studies on causes of diseases...
Autoantibodies binding to citrullinated telopeptide of type II collagen and to cyclic citrullinated peptides predict synergistically the development of seropositive rheumatoid arthritisMarja Kaisa Koivula
Department of Clinical Chemistry, University of Oulu and University of Turku, Oulu and Turku, Finland
Ann Rheum Dis 66:1450-5. 2007..To find out whether autoantibodies to citrullinated telopeptides of type I and II collagens and to cyclic citrullinated peptides (CCPs) predict the development of rheumatoid arthritis (RA)...
Association of overweight with increased risk of coronary heart disease partly independent of blood pressure and cholesterol levels: a meta-analysis of 21 cohort studies including more than 300 000 personsRik P Bogers
Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment, PO Box 1, 3720 BA Bilthoven, The Netherlands
Arch Intern Med 167:1720-8. 2007..0) are associated with increased risk of coronary heart disease (CHD) through adverse effects on blood pressure and cholesterol levels is unclear, as is the risk of CHD that remains after these mediating effects are considered...
Osteoarthritis in the carpometacarpal joint of the thumb. Prevalence and associations with disability and mortalityMikko M Haara
Department of Orthopaedic Surgery, Kuopio University Hospital, P O Box 1627, FIN 70211 Kuopio, Finland
J Bone Joint Surg Am 86:1452-7. 2004..This study was designed to investigate the prevalence of osteoarthritis in the carpometacarpal joint of the thumb in adults thirty years of age or older in Finland...
