Tuula Kieseppä

Summary

Affiliation: National Public Health Institute
Country: Finland

Publications

  1. ncbi High concordance of bipolar I disorder in a nationwide sample of twins
    Tuula Kieseppä
    Department of Mental Health and Alcohol Research, National Public Health Institute, 00300 Helsinki 30, Finland
    Am J Psychiatry 161:1814-21. 2004
  2. ncbi Memory and verbal learning functions in twins with bipolar-I disorder, and the role of information-processing speed
    Tuula Kieseppä
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Psychol Med 35:205-15. 2005
  3. ncbi Major depressive disorder and white matter abnormalities: a diffusion tensor imaging study with tract-based spatial statistics
    Tuula Kieseppä
    Department of Mental Health and Alcohol Research, National Public Heath Institute, Finland
    J Affect Disord 120:240-4. 2010
  4. ncbi Cognitive functioning of bipolar I patients and relatives from families with or without schizophrenia or schizoaffective disorder
    Mervi Antila
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    J Affect Disord 116:70-9. 2009
  5. ncbi Reduced left hemispheric white matter volume in twins with bipolar I disorder
    Tuula Kieseppä
    Department of Mental Health and Alcohol Research, University of Helsinki, Finland
    Biol Psychiatry 54:896-905. 2003
  6. ncbi Association of AKT1 with verbal learning, verbal memory, and regional cortical gray matter density in twins
    Olli P H Pietiläinen
    FIMM, Institute for Molecular Medicine Finland and National Public Health Institute, Biomedicum, Helsinki, Finland
    Am J Med Genet B Neuropsychiatr Genet 150:683-92. 2009
  7. ncbi Identification of susceptibility loci at 7q31 and 9p13 for bipolar disorder in an isolated population
    Outi M Palo
    FIMM, Institute for Molecular Medicine and National Institute for Health and Welfare, Helsinki, Finland
    Am J Med Genet B Neuropsychiatr Genet 153:723-35. 2010
  8. ncbi Heritability of cognitive functions in families with bipolar disorder
    Mervi Antila
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Am J Med Genet B Neuropsychiatr Genet 144:802-8. 2007
  9. ncbi The effect of seasons and seasonal variation on neuropsychological test performance in patients with bipolar I disorder and their first-degree relatives
    Elina Rajajärvi
    Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    J Affect Disord 127:58-65. 2010
  10. ncbi Association of a nonsynonymous variant of DAOA with visuospatial ability in a bipolar family sample
    Pia Soronen
    Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland
    Biol Psychiatry 64:438-42. 2008

Detail Information

Publications19

  1. ncbi High concordance of bipolar I disorder in a nationwide sample of twins
    Tuula Kieseppä
    Department of Mental Health and Alcohol Research, National Public Health Institute, 00300 Helsinki 30, Finland
    Am J Psychiatry 161:1814-21. 2004
    ..The authors report what appears to be the first twin study of bipolar I disorder involving a population-based twin sample, in which the diagnoses were made by using structured, personal interviews...
  2. ncbi Memory and verbal learning functions in twins with bipolar-I disorder, and the role of information-processing speed
    Tuula Kieseppä
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Psychol Med 35:205-15. 2005
    ..The authors compared verbal learning and memory functioning in twins with BP I and co-twins to control twins, and examined whether the observed deficits are related to information-processing speed...
  3. ncbi Major depressive disorder and white matter abnormalities: a diffusion tensor imaging study with tract-based spatial statistics
    Tuula Kieseppä
    Department of Mental Health and Alcohol Research, National Public Heath Institute, Finland
    J Affect Disord 120:240-4. 2010
    ..In this study, we explored the structure of the white matter of the whole brain with DTI in middle-aged major depressive disorder (MDD) patients, using novel tract-based spatial statistics...
  4. ncbi Cognitive functioning of bipolar I patients and relatives from families with or without schizophrenia or schizoaffective disorder
    Mervi Antila
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    J Affect Disord 116:70-9. 2009
    ....
  5. ncbi Reduced left hemispheric white matter volume in twins with bipolar I disorder
    Tuula Kieseppä
    Department of Mental Health and Alcohol Research, University of Helsinki, Finland
    Biol Psychiatry 54:896-905. 2003
    ....
  6. ncbi Association of AKT1 with verbal learning, verbal memory, and regional cortical gray matter density in twins
    Olli P H Pietiläinen
    FIMM, Institute for Molecular Medicine Finland and National Public Health Institute, Biomedicum, Helsinki, Finland
    Am J Med Genet B Neuropsychiatr Genet 150:683-92. 2009
    ..The established association of the same allelic variant of AKT1 with both cognitive and neuroanatomical aberrations could suggest that AKT1 exerts its effect on verbal learning and memory via neural networks involving prefrontal cortex...
  7. ncbi Identification of susceptibility loci at 7q31 and 9p13 for bipolar disorder in an isolated population
    Outi M Palo
    FIMM, Institute for Molecular Medicine and National Institute for Health and Welfare, Helsinki, Finland
    Am J Med Genet B Neuropsychiatr Genet 153:723-35. 2010
    ..The loci on the centromeric region of 9p13 and the telomeric region of 7q31 may represent susceptibility loci for mood disorder in the Finnish population...
  8. ncbi Heritability of cognitive functions in families with bipolar disorder
    Mervi Antila
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Am J Med Genet B Neuropsychiatr Genet 144:802-8. 2007
    ..Genetic contribution was low to verbal learning functions. High heritability, in executive functioning and psychomotor processing speed suggest that these may be valid endophenotypic traits for genetic studies of bipolar disorder...
  9. ncbi The effect of seasons and seasonal variation on neuropsychological test performance in patients with bipolar I disorder and their first-degree relatives
    Elina Rajajärvi
    Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    J Affect Disord 127:58-65. 2010
    ....
  10. ncbi Association of a nonsynonymous variant of DAOA with visuospatial ability in a bipolar family sample
    Pia Soronen
    Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland
    Biol Psychiatry 64:438-42. 2008
    ..Bipolar disorder and schizophrenia are hypothesized to share some genetic background...
  11. ncbi Executive functioning in twins with bipolar I disorder and healthy co-twins
    Susanna Juselius
    Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    Arch Clin Neuropsychol 24:599-606. 2009
    ..The impaired performance in the semantic fluency test among the patients may result from semantic memory retrieval problems...
  12. ncbi The effect of processing speed on cognitive functioning in patients with familial bipolar I disorder and their unaffected relatives
    Mervi Antila
    Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    Psychopathology 44:40-5. 2011
    ..Despite increasing evidence of cognitive dysfunctions in bipolar I disorder, there is no specific neuropsychological profile of the disorder...
  13. ncbi Spatial working memory function in twins with schizophrenia and bipolar disorder
    Tiia Pirkola
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Biol Psychiatry 58:930-6. 2005
    ..Here, we evaluated whether such deficits might also mark genetic susceptibility to bipolar disorder...
  14. ncbi Circadian phenotype in patients with the co-morbid alcohol use and bipolar disorders
    Taina Hätönen
    Department of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, FI 00300 Helsinki, Finland
    Alcohol Alcohol 43:564-8. 2008
    ..We aimed at analysing the behavioural trait of the preference to morning or evening hours for the daily activities in bipolar disorder patients with or without the co-morbid alcohol use...
  15. ncbi Lifetime prevalence of psychotic and bipolar I disorders in a general population
    Jonna Perälä
    Department of Mental Health and Alcohol Research, National Public Health Institute, University of Helsinki, Mannerheimintie 166, 0300 Helsinki, Finland
    Arch Gen Psychiatry 64:19-28. 2007
    ..Recent general population surveys of psychotic disorders have found low lifetime prevalences. However, this may be owing to methodological problems. Few studies have reported the prevalences of all specific psychotic disorders...
  16. ncbi Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments
    Outi M Palo
    Department of Molecular Medicine, National Public Health Insitute, Helsinki, Finland
    Hum Mol Genet 16:2517-28. 2007
    ..Finding of alternative associating haplotypes in the same set of BPD families gives evidence for allelic heterogeneity within DISC1, eventually leading to heterogeneity in the clinical outcome as well...
  17. ncbi Cognitive functioning in patients with familial bipolar I disorder and their unaffected relatives
    Mervi Antila
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Psychol Med 37:679-87. 2007
    ..The aim was to discover whether any cognitive function would indicate genetic liability to the disorder and could thus be regarded as endophenotypes of BPD...
  18. ncbi Seasonal changes, sleep length and circadian preference among twins with bipolar disorder
    Reeta Hakkarainen
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    BMC Psychiatry 3:6. 2003
    ..We aimed at studying the seasonal changes in mood and behaviour, the distribution of hospital admissions by season, and the persistence of the circadian type in twins with bipolar disorder and their healthy co-twins...
  19. ncbi Evidence of susceptibility loci on 4q32 and 16p12 for bipolar disorder
    Jenny M Ekholm
    Department of Molecular Medicine, National Public Health Institute, 00251 Helsinki, Finland
    Hum Mol Genet 12:1907-15. 2003
    ..7. Since the identified chromosomal regions replicate earlier linkage findings in either bipolar disorder or other mental disorders, they should be considered good targets for further genetic analyses...