Gang Hu

..This study examined the age- and sex-specific prevalence of the metabolic syndrome and its association with all-cause and cardiovascular mortality in nondiabetic European men and women...

..To evaluate whether type 2 diabetes at baseline is a risk factor for Parkinson's disease...

..Some previous studies have assessed the association between leisure-time physical activity and mortality among patients with diabetes, but the potential effect of occupational and commuting physical activity remains uncertain...

..To determine joint associations of different kinds of physical activity and the Framingham risk score (FRS) with the 10-year risk of coronary heart disease (CHD) events...

..To examine the association between body mass index (BMI) and the risk of Parkinson disease (PD)...

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..To examine the association of different levels of occupational, commuting, and leisure-time physical activity with the risk of coronary heart disease (CHD) events...

..To assess joint associations of physical activity and different indicators of obesity (body mass index, waist circumference, and waist-to-hip ratio) with the risk of cardiovascular disease (CVD)...

..The aim of this study was to compare the magnitude of the effect of diabetes and stroke at baseline and during follow-up on risk of stroke mortality...

..We assessed the relationship of different types of physical activity with total and type-specific stroke risk...

..OBJECTIVe: To examine joint associations of coffee consumption and other factors (including physical activity, obesity and alcohol consumption) with the risk of type 2 diabetes...

..To examine the association of physical activity and body mass index (BMI), and their combined effect, with the risk of total, cardiovascular disease (CVD) and cancer mortality...

..The aim of this study was to examine both single and joint associations of physical activity and conventional cardiovascular risk factors with total and cardiovascular mortality among patients with diabetes...

..We investigated the associations of type 2 diabetes and a history of myocardial infarction (MI) with coronary heart disease, stroke, cardiovascular and total mortality, and whether these effects are different in men and women...

..The goal of this study is to compare the magnitude of diabetes and myocardial infarction (MI) at baseline and during follow-up on cause-specific and all-cause mortality...

..We evaluated prospectively the joint association of history of hypertension and type 2 diabetes on the incidence of stroke and stroke mortality...

..Sedentary lifestyle, obesity, and impaired glucose regulation are associated with the risk of type 2 diabetes. However, the joint associations of these risk factors are not known...

..Adiposity is an established risk factor for cardiovascular disease, but the relationship of adiposity with the risk of cerebrovascular disease is still to some extent unclear...

..CONCLUSION: Coffee drinking has an inverse and graded association with the risk of liver cancer. High serum GGT is associated with an increased risk of liver cancer...

..In Finland, the biggest task seems to be the reduction of weight and lipid abnormalities, and the prevention of hypertension...

..The association of high salt intake, insulin resistance, and salt sensitivity, and the interaction between high salt intake, heart rate, and blood pressure are debated...

..To examine the association between serum total cholesterol at baseline and the risk of Parkinson disease (PD)...

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..Our objective was to assess a 10-yr change in the prevalence of the metabolic syndrome defined by the National Cholesterol Education Program (NCEP) and the International Diabetes Federation (IDF) among Finnish men and women...

..To evaluate the joint associations of history of hypertension at baseline and type 2 diabetes at baseline and during follow-up on the incidence of coronary heart disease (CHD) and CHD mortality...

..The aim of this study was to assess whether high salt intake, measured by 24-h urinary sodium excretion, is an independent risk factor for type 2 diabetes...

..Only 2 prospective studies have previously investigated the association between coffee consumption and incident hypertension, and the findings are equivocal...

..41 (95% CI 0.20-0.83). These results suggest that coffee drinking is associated with a lower risk of PD. More tea drinking is associated with a lower risk of PD...

..The purpose of this study was to determine the association of occupational, commuting, and leisure-time physical activity on cardiovascular mortality among hypertensive patients...

..The aim of this study is to evaluate whether the association between different degrees of hyperglycaemia and the risk of all-cause and cardiovascular mortality is different in women and men...

..This study is to examine the relationship of occupational, commuting and leisure-time physical activity with the incidence of Type 2 diabetes...

..To investigate physical activity during leisure time and commuting among persons aged 15-69 years in the urban population of Tianjin, China, and to assess its associations with demographic and health-related characteristics...

..The relationship between both commuting and leisure-time physical activity and selected cardiovascular risk factors was analyzed...

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..The aim of this study was to examine how the major components of the metabolic syndrome relate to each other and to the development of diabetes using factor analysis...

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..Our objective was to assess whether the association of serum C-reactive protein (CRP) with type 2 diabetes risk is modified by sex...

..None of the five definitions predicted either incident CHD alone (177 cases) or total incident CHD (236 cases). In conclusion, the MetS defined by the current definitions appears to be more effective at predicting incident diabetes...

..The direction of the association between high socio-economic status and poor serum lipid profiles appears to be opposite to those observed in the developed countries...

..To report the age- and sex-specific prevalence of diabetes and impaired glucose regulation (IGR) according to revised World Health Organization criteria for diabetes in Asian populations...

..Only a few studies of coffee consumption and diabetes mellitus (DM) have been reported, even though coffee is the most consumed beverage in the world...

..The present study indicates that regular physical activity and weight control can reduce the risk of hypertension. The protective effect of physical activity was observed in both sexes regardless of the level of obesity...

..We investigated this question in a prospective study of middle-aged men and women...

..To investigate whether there are differences in stroke risk among hypertensive men and women by awareness, treatment and blood pressure control status at baseline...

..Our review of the scientific evidence confirms that 30 min/d of moderate- or high-level physical activity is an effective and safe way to prevent type 2 diabetes in all populations...

..To analyse the association between both commuting and leisure time physical activity and serum lipids in a Chinese population...

..Prevention of smoking should be encouraged as a part of efforts to reduce the risk of type 2 diabetes, and it will result in other health benefits, too...

..To ascertain which impaired glucose homeostasis at baseline is predictive of conversion to type 2 diabetes in both men and women in a high-risk non-diabetic population...

..This study was designed to assess the association between coffee consumption and CVD mortality among patients with type 2 diabetes...

..To assess the sensitivity and specificity of the four definitions of the metabolic syndrome for incident diabetes in both men and women...

..To examine how thinness is associated with indicators of socio-economic disadvantage, health-related behaviours, and health indicators including mortality...

..Coffee has several metabolic effects that could reduce the risk of type 2 diabetes. Our objective was to examine the effects of coffee consumption on glucose tolerance, glucose and insulin levels...

..To study the joint association of coffee consumption and serum gamma-glutamyltransferase (GGT) levels on the risk of developing type II diabetes...

..The aim of this study is to examine this relationship among Finns, who are the heaviest coffee consumers in the world...

..dietary sodium intake and dietary sodium-to-potassium ratio were positively associated with high BP. Education level in women and commuting physical activity in men were inversely associated with high BP...

..The gene-environment interactions merit extensive exploration in large, prospective studies...

..Since both high fat diet and insulin deficiency are closely linked with etiology of Type II diabetes, the evidence in this study suggests a role of DPP-IV in development of Type II diabetes...

..Iptakalim might be a promising novel candidate for the prevention and/or treatment of stroke...

..This study examined if serum GGT predicted coronary heart disease (CHD), especially differentiating non-fatal myocardial infarction (MI) and fatal CHD event, among the general population or participants with type-2 diabetes...

..The aims of this study were to assess the predictive value of glucose tolerance status as a risk factor for CVD and identify a high-risk group for fatal CVD in population-based studies of Asians...

..The mutual desensitization of the responses to ATP and high K+ strongly suggests that both agents rely at least in part on the same source of Ca2+ for elevation of [Ca2+]i in NG 108-15 cells...

..We propose that ITF-2 is a TCF-regulated gene, which functions in concert with other TCF target genes to promote growth and/or survival of cancer cells with defects in beta-catenin regulation...

..This experiment provides the in vivo evidence that AQP4 participates in the regulation of neurotransmitter release induced by depolarizing stimuli...

..GSx levels decreased because of increased gammaGT mRNA levels and gammaGT activity induced by 6-OHDA after treatment for 48 h...

..These results provide the first evidence that the lack of AQP4 expression is accompanied by sex- and region-specific alterations in brain amino acid and monoamine metabolism...

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..CONCLUSION: 11beta-HSD1 may promote preadipocyte differentiation, and may be involved in the development of obesity...

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..This compound thus has promise as a neuroprotective drug for the treatment of stroke and other forms of neuronal damage...

..CONCLUSION: It is necessary to remove and reduce currently active sources of lead pollution in the community and to increase public awareness of potential health effects of lead exposure...

..These data strongly suggest that the K(ATP) opener IPT may be a novel and promising neuroprotective drug via inhibiting microglia-mediated neuroinflammation...

..ii) KATP channels regulate extracellular neurotransmitter levels in the striatum of unilateral 6-OHDA-lesioned rats and may play neuroprotective roles due to their effects on glutamate transporters...