Jari Haukka

Summary

Affiliation: National Public Health Institute
Country: Finland

Publications

  1. doi request reprint Determinants and outcomes of serious attempted suicide: a nationwide study in Finland, 1996-2003
    Jari Haukka
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Am J Epidemiol 167:1155-63. 2008
  2. doi request reprint Circadian clock gene polymorphisms in alcohol use disorders and alcohol consumption
    Leena Kovanen
    Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    Alcohol Alcohol 45:303-11. 2010
  3. pmc Psychosis among "healthy" siblings of schizophrenia patients
    Ritva Arajärvi
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    BMC Psychiatry 6:6. 2006
  4. doi request reprint Hopelessness across phases of bipolar I or II disorder: a prospective study
    Hanna M Valtonen
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    J Affect Disord 115:11-7. 2009
  5. ncbi request reprint High concordance of bipolar I disorder in a nationwide sample of twins
    Tuula Kieseppä
    Department of Mental Health and Alcohol Research, National Public Health Institute, 00300 Helsinki 30, Finland
    Am J Psychiatry 161:1814-21. 2004
  6. ncbi request reprint Incidence of schizophrenia in a nationwide cohort of patients with type 1 diabetes mellitus
    Hannu Juvonen
    Department of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland
    Arch Gen Psychiatry 64:894-9. 2007
  7. doi request reprint The association between social determinants and drunken driving: a 15-year register-based study of 81,125 suspects
    Antti Impinen
    National Institute for Health and Welfare, Helsinki, Finland
    Alcohol Alcohol 46:721-8. 2011
  8. ncbi request reprint Affective flattening and alogia associate with the familial form of schizophrenia
    Ritva Arajärvi
    National Public Health Institute, Department of Mental Health and Alcohol Research, University of Helsinki, Mannerheimintie 166, 00300 Helsinki, Finland
    Psychiatry Res 141:161-72. 2006
  9. doi request reprint Geographic variation and sociodemographic characteristics of psychotic disorders in Finland
    Jonna Perälä
    National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland
    Schizophr Res 106:337-47. 2008
  10. ncbi request reprint Spatial working memory function in twins with schizophrenia and bipolar disorder
    Tiia Pirkola
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Biol Psychiatry 58:930-6. 2005

Detail Information

Publications66

  1. doi request reprint Determinants and outcomes of serious attempted suicide: a nationwide study in Finland, 1996-2003
    Jari Haukka
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Am J Epidemiol 167:1155-63. 2008
    ..57, 2.21) and mood disorders (SHR = 1.72, 95% CI: 1.47, 2.01) were associated with the risk of suicide. The risks of suicide and all-cause mortality were extremely high immediately after hospitalization for attempted suicide...
  2. doi request reprint Circadian clock gene polymorphisms in alcohol use disorders and alcohol consumption
    Leena Kovanen
    Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    Alcohol Alcohol 45:303-11. 2010
    ..Our aim was to study whether circadian clock gene polymorphisms predispose to alcohol dependence or abuse or other alcohol-related characteristics...
  3. pmc Psychosis among "healthy" siblings of schizophrenia patients
    Ritva Arajärvi
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    BMC Psychiatry 6:6. 2006
    ..We also analyzed the emergence of psychotic disorders among siblings of patients with schizophrenia during seven to eleven years of follow-up...
  4. doi request reprint Hopelessness across phases of bipolar I or II disorder: a prospective study
    Hanna M Valtonen
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    J Affect Disord 115:11-7. 2009
    ..We investigated the degree to which hopelessness is trait- or state-related during the course of BD...
  5. ncbi request reprint High concordance of bipolar I disorder in a nationwide sample of twins
    Tuula Kieseppä
    Department of Mental Health and Alcohol Research, National Public Health Institute, 00300 Helsinki 30, Finland
    Am J Psychiatry 161:1814-21. 2004
    ..The authors report what appears to be the first twin study of bipolar I disorder involving a population-based twin sample, in which the diagnoses were made by using structured, personal interviews...
  6. ncbi request reprint Incidence of schizophrenia in a nationwide cohort of patients with type 1 diabetes mellitus
    Hannu Juvonen
    Department of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland
    Arch Gen Psychiatry 64:894-9. 2007
    ..Patients with schizophrenia have an increased risk of type 2 diabetes mellitus. However, very few studies have dealt with the association of type 1 diabetes and schizophrenia. Preliminary evidence points to a possible inverse association...
  7. doi request reprint The association between social determinants and drunken driving: a 15-year register-based study of 81,125 suspects
    Antti Impinen
    National Institute for Health and Welfare, Helsinki, Finland
    Alcohol Alcohol 46:721-8. 2011
    ..The aim of the study was to examine the association between social background and drunken driving...
  8. ncbi request reprint Affective flattening and alogia associate with the familial form of schizophrenia
    Ritva Arajärvi
    National Public Health Institute, Department of Mental Health and Alcohol Research, University of Helsinki, Mannerheimintie 166, 00300 Helsinki, Finland
    Psychiatry Res 141:161-72. 2006
    ..This may be related to genetic homogeneity in the isolate. We conclude that patients with first-degree relatives with psychotic disorder have more severe negative symptoms...
  9. doi request reprint Geographic variation and sociodemographic characteristics of psychotic disorders in Finland
    Jonna Perälä
    National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland
    Schizophr Res 106:337-47. 2008
    ..We examined the geographical variation in the lifetime prevalence of psychotic disorders in a comprehensive general population study...
  10. ncbi request reprint Spatial working memory function in twins with schizophrenia and bipolar disorder
    Tiia Pirkola
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Biol Psychiatry 58:930-6. 2005
    ..Here, we evaluated whether such deficits might also mark genetic susceptibility to bipolar disorder...
  11. doi request reprint Seasonal vegetative and affective symptoms in the Finnish general population: testing the dual vulnerability and latitude effect hypotheses
    Sharon Grimaldi
    National Institute for Health and Welfare, Helsinki, Finland
    Nord J Psychiatry 63:397-404. 2009
    ....
  12. ncbi request reprint Clinical phenotype of schizophrenia in a Finnish isolate
    Ritva Arajärvi
    Department of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, Helsinki 00300, Finland
    Schizophr Res 67:195-205. 2004
    ..Findings in this schizophrenia OCCPI phenotype study suggest that the clinical picture of schizophrenia in a genetically isolated and homogeneous population closely resembles our nationwide findings in Finland...
  13. ncbi request reprint Heritability of cognitive functions in families with bipolar disorder
    Mervi Antila
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Am J Med Genet B Neuropsychiatr Genet 144:802-8. 2007
    ..Genetic contribution was low to verbal learning functions. High heritability, in executive functioning and psychomotor processing speed suggest that these may be valid endophenotypic traits for genetic studies of bipolar disorder...
  14. doi request reprint Differences in incidence of suicide attempts during phases of bipolar I and II disorders
    Hanna M Valtonen
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Bipolar Disord 10:588-96. 2008
    ..Differences in the incidence of suicide attempts during various phases of bipolar disorder (BD), or the relative importance of static versus time-varying risk factors for overall risk for suicide attempts, are unknown...
  15. ncbi request reprint Prevalence and diagnosis of schizophrenia based on register, case record and interview data in an isolated Finnish birth cohort born 1940-1969
    Ritva Arajärvi
    Dept of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, 00300, Helsinki, Finland
    Soc Psychiatry Psychiatr Epidemiol 40:808-16. 2005
    ....
  16. doi request reprint Antidepressant use and mortality in Finland: a register-linkage study from a nationwide cohort
    Jari Haukka
    National Institute for Health and Welfare, Helsinki, Finland
    Eur J Clin Pharmacol 65:715-20. 2009
    ..It is generally acknowledged that depressed patients need specific attention during the first weeks after initiation of antidepressant (AD) treatment because of the increased risk of suicide...
  17. ncbi request reprint Memory and verbal learning functions in twins with bipolar-I disorder, and the role of information-processing speed
    Tuula Kieseppä
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Psychol Med 35:205-15. 2005
    ..The authors compared verbal learning and memory functioning in twins with BP I and co-twins to control twins, and examined whether the observed deficits are related to information-processing speed...
  18. doi request reprint An association between high birth weight and schizophrenia in a Finnish schizophrenia family study sample
    Asko Wegelius
    National Institute for Health and Welfare, Department of Mental Health and Substance Abuse Services, Helsinki, Finland
    Psychiatry Res 190:181-6. 2011
    ..Our results also point to a potential birth-weight independent association between maternal type 2 diabetes and schizophrenia among offspring...
  19. doi request reprint Incidence of cancer and statin usage--record linkage study
    Jari Haukka
    Data Analysis and Interpretation Group, International Agency for Research on Cancer, Helsinki, Finland
    Int J Cancer 126:279-84. 2010
    ..We found neither beneficial nor harmful associations between the usage of statins and cancer...
  20. doi request reprint Categorical and dimensional stability of comorbid personality disorder symptoms in DSM-IV major depressive disorder: a prospective study
    Tarja K Melartin
    Mood, Depression, and Suicidal Behavior Unit, National Institute for Health and Welfare, Helsinki, Finland
    J Clin Psychiatry 71:287-95. 2010
    ....
  21. doi request reprint Incidence and predictors of suicide attempts in DSM-IV major depressive disorder: a five-year prospective study
    K Mikael Holma
    Mood, Depression, and Suicidal Behavior Unit, National Institute for Health and Welfare, Helsinki, Finland
    Am J Psychiatry 167:801-8. 2010
    ..Therefore, the importance of state factors, particularly time spent in risk states, for overall risk remains unknown...
  22. doi request reprint Increase in the duration of antidepressant treatment from 1994 to 2003: a nationwide population-based study from Finland
    Sinikka Sihvo
    THL National Institute for Health and Welfare, Helsinki, Finland
    Pharmacoepidemiol Drug Saf 19:1186-93. 2010
    ..We examined the length and continuity of antidepressant treatment and factors associated with long-term of treatment among adults...
  23. ncbi request reprint Age at onset and cognitive functioning in schizophrenia
    Annamari Tuulio-Henriksson
    National Public Health Institute, Department of Mental Health and Alcohol Research, Mannerheimintie 166, 00300 Helsinki, Finland
    Br J Psychiatry 185:215-9. 2004
    ..Impairments in cognitive functioning are common in schizophrenia, and the degree of impairment may be associated with the individual's age at onset of the disorder...
  24. ncbi request reprint Completed suicide after a suicide attempt: a 37-year follow-up study
    Kirsi Suominen
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Am J Psychiatry 161:562-3. 2004
    ..However, suicide risk declines over time after an attempt, and it is unclear how long the risk persists. Risk estimates are almost exclusively based on studies of less than 10 years of follow-up...
  25. ncbi request reprint Is low dietary intake of omega-3 fatty acids associated with depression?
    Reeta Hakkarainen
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Am J Psychiatry 161:567-9. 2004
    ..This study examined the association between the dietary intake of omega-3 fatty acids and low mood, major depression, and suicide...
  26. doi request reprint Inflammation in psychotic disorders: a population-based study
    Jaana Suvisaari
    Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    Psychiatry Res 189:305-11. 2011
    ....
  27. doi request reprint Association between medication and risk of suicide, attempted suicide and death in nationwide cohort of suicidal patients with schizophrenia
    Jari Haukka
    Department of Mental Health and Alcohol Research, National Public Health Institute, FIN 00300 Helsinki, Finland
    Pharmacoepidemiol Drug Saf 17:686-96. 2008
    ..The aim of this study was to investigate, in a nationwide cohort of suicidal schizophrenic individuals, how the risks of suicide, severe suicide attempts and death are associated with usage of antidepressant or antipsychotic treatment...
  28. doi request reprint P2RX7 gene is associated consistently with mood disorders and predicts clinical outcome in three clinical cohorts
    Pia Soronen
    Public Health Genomics Unit, Institute for Molecular Medicine FIMM, National Institute for Health and Welfare, Helsinki, Finland
    Am J Med Genet B Neuropsychiatr Genet 156:435-47. 2011
    ..The same risk alleles resulted in clinically significant differences in outcome of patients with major depressive and bipolar disorder...
  29. doi request reprint Statin usage and all-cause and disease-specific mortality in a nationwide study
    Jari Haukka
    Department of Public Health, University of Helsinki, Helsinki, Finland Department of Mental Health and Alcohol Research, National Institute for Health and Welfare, Helsinki, Finland
    Pharmacoepidemiol Drug Saf 21:61-9. 2012
    ..The consumption of statins (HMG-CoA reductase inhibitors) in most Western countries has increased to the extent that it may affect all-cause and disease-specific mortality...
  30. ncbi request reprint High concordance between self-reported medication and official prescription database information
    Jari Haukka
    Department for Mental Health and Alcohol Research, Mannerheimintie 166, 00300, Helsinki, Finland
    Eur J Clin Pharmacol 63:1069-74. 2007
    ..We compared the point prevalence of psychotropic medication use, and self-reported vs. register-based information on antipsychotic medication dosage...
  31. pmc Seasonal changes in mood and behavior are linked to metabolic syndrome
    Reeta Rintamäki
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    PLoS ONE 3:e1482. 2008
    ..Metabolic syndrome is a risk factor to the cardiovascular diseases. It has been reported that disruptions of the circadian clockwork are associated with and may predispose to metabolic syndrome...
  32. ncbi request reprint Childhood central nervous system viral infections and adult schizophrenia
    Jaana Suvisaari
    Department of Mental Health and Alcohol Research and the Deparment of Virology, National Puablic Health Institute, Helsinki, Finland
    Am J Psychiatry 160:1183-5. 2003
    ..An earlier Finnish cohort study suggested that childhood viral CNS infections are associated with a fivefold increased odds of developing schizophrenia in adulthood. The authors sought to replicate this finding...
  33. ncbi request reprint Reduced left hemispheric white matter volume in twins with bipolar I disorder
    Tuula Kieseppä
    Department of Mental Health and Alcohol Research, University of Helsinki, Finland
    Biol Psychiatry 54:896-905. 2003
    ....
  34. doi request reprint Serotonin transporter polymorphism as a predictor for escitalopram treatment of major depressive disorder comorbid with alcohol dependence
    Leea H Muhonen
    National Institute for Health and Welfare, Department of Mental Health and Substance Abuse Services, Helsinki, Finland
    Psychiatry Res 186:53-7. 2011
    ..This is the first study in the treatment of depression in dual diagnosis patients to report a significant association between outcomes with escitalopram and the 5-HTTLPR gene polymorphism...
  35. doi request reprint Incidence of cancer and antidepressant medication: record linkage study
    Jari Haukka
    Data Analysis and Interpretation Group, International Agency for Research on Cancer, Helsinki, Finland
    Int J Cancer 126:285-96. 2010
    ..As conclusion, no clear evidence of neither beneficial nor harmful association between usage of antidepressant and cancer was found...
  36. pmc Effect of simulated dawn on quality of sleep--a community-based trial
    Sami Leppämäki
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    BMC Psychiatry 3:14. 2003
    ..Disturbances in sleep patterns are common and may compromise wellbeing even in the short term. Our hypothesis was that simulated dawn could improve the subjective quality of sleep during winter...
  37. ncbi request reprint Substance use and male gender as risk factors for deaths and suicide--a 5-year follow-up study after deliberate self-harm
    Kirsi Suominen
    Dept of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland
    Soc Psychiatry Psychiatr Epidemiol 39:720-4. 2004
    ..The aim of this study was to determine the mortality by suicide and other causes of death in a cohort of suicide attempters and identify predictive factors, including contact to healthcare after the attempt...
  38. pmc Daylight saving time transitions and hospital treatments due to accidents or manic episodes
    Tuuli A Lahti
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    BMC Public Health 8:74. 2008
    ..The aim of this study was to explore the effects of transitions into and out of daylight saving time on the incidence of accidents and manic episodes in the Finnish population during the years of 1987 to 2003...
  39. ncbi request reprint Familial loading associates with impairment in visual span among healthy siblings of schizophrenia patients
    Annamari Tuulio-Henriksson
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Biol Psychiatry 54:623-8. 2003
    ..The present study examined this effect among healthy siblings of schizophrenia patients in a Finnish isolate with high prevalence of schizophrenia...
  40. ncbi request reprint Cyclic time patterns of death from suicide in northern Finland
    Timo Partonen
    Department of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    J Affect Disord 78:11-9. 2004
    ..Seasonal variations in day length and temperature seem likely to contribute to the timing of the suicide process...
  41. doi request reprint Socio-economic determinants of drugged driving--a register-based study
    Karoliina Karjalainen
    National Institute for Health and Welfare, Helsinki, Finland
    Addiction 106:1448-59. 2011
    ..To examine the associations between socio-economic characteristics and driving under the influence of drugs (DUID), and to elaborate determinants of drugged driving...
  42. pmc NPAS2 and PER2 are linked to risk factors of the metabolic syndrome
    Ani Englund
    Department of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, FI 00300 Helsinki, Finland
    J Circadian Rhythms 7:5. 2009
    ..Our aim was to analyze whether circadian clock polymorphisms contribute to seasonal variations in behavior and to the metabolic syndrome...
  43. pmc Transition into daylight saving time influences the fragmentation of the rest-activity cycle
    Tuuli A Lahti
    Department of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, FI 00300 Helsinki, Finland
    J Circadian Rhythms 4:1. 2006
    ..01). CONCLUSION : Transition into daylight saving time may have a disruptive effect on the rest-activity cycle in those healthy adults who are short-sleepers or more of the evening type...
  44. ncbi request reprint Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects
    William Hennah
    Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland
    Hum Mol Genet 12:3151-9. 2003
    ..Our findings would also encourage more detailed analyses of the effect of DISC1 on the component-traits of schizophrenia...
  45. ncbi request reprint Analysis of the seasonal pattern in suicide
    Timo Partonen
    Department of Mental Health and Alcohol Research, National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    J Affect Disord 81:133-9. 2004
    ..Suicide has been attributed to social and psychological factors but also to geophysical effects. Of the latter, changes in solar radiation and geomagnetic activities may contribute to the frequency and the seasonal pattern of suicides...
  46. ncbi request reprint Mortality among patients with schizophrenia and reduced psychiatric hospital care
    Hannele Heila
    National Public Health Institute, Department of Mental Health and Alcohol Research, Mannerheimintie, Helsinki, Finland
    Psychol Med 35:725-32. 2005
    ..We investigated the mortality of schizophrenia patients in the general population of Finland during the reduction of psychiatric beds during 1980-1996...
  47. pmc Drop-out and mood improvement: a randomised controlled trial with light exposure and physical exercise [ISRCTN36478292]
    Sami Leppämäki
    Department of Mental Health and Alcohol Research, Unit for Epidemiology and Genetics of Mental Health, National Public Health Institute, Helsinki, Finland
    BMC Psychiatry 4:22. 2004
    ..We explored background variables possibly explaining the individual variation in treatment response or failure in a randomised trial...
  48. ncbi request reprint Association of dietary amino acids with low mood
    Reeta Hakkarainen
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Depress Anxiety 18:89-94. 2003
    ..There is no consistent association between dietary intake of amino acids and low mood...
  49. ncbi request reprint Increasing age does not decrease risk of schizophrenia up to age 40
    Jari Haukka
    Department of Mental Health and Alcohol Research, KTL, National Public Health Institute, Mannerheimintie 160, FIN 00300 Helsinki, Finland
    Schizophr Res 61:105-10. 2003
    ..This increase is more rapid among males. The reasons behind the lower proportion of susceptibles in younger birth cohorts, as well reasons for differences in risk between sexes remained unclear and need more research...
  50. ncbi request reprint How does a history of psychiatric hospital care influence access to coronary care: a cohort study
    Kristiina Manderbacka
    National Institute for Health and Welfare, Helsinki, Finland
    BMJ Open 2:e000831. 2012
    ..The aim of this cohort study was to examine equity in access to coronary care among persons with a history of severe mental disorder in 1998-2009...
  51. ncbi request reprint Fertility of patients with schizophrenia, their siblings, and the general population: a cohort study from 1950 to 1959 in Finland
    Jari Haukka
    Kansanterveyslaitos, National Public Health Institute, Helsinki, Finland
    Am J Psychiatry 160:460-3. 2003
    ..The authors investigated whether the siblings of patients with schizophrenia produce more offspring, thereby compensating for the low fertility of the affected individuals...
  52. ncbi request reprint Timed bright-light exposure and complaints related to shift work among women
    Sami Leppämäki
    National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland
    Scand J Work Environ Health 29:22-6. 2003
    ..A secondary objective was to investigate whether this response differed by season (summer or winter), seasonality, or age...
  53. doi request reprint Genetics of pubertal timing and its associations with relative weight in childhood and adult height: the Swedish Young Male Twins Study
    Karri Silventoinen
    Department of Public Health, University of Helsinki, Helsinki, Finland
    Pediatrics 121:e885-91. 2008
    ..Because the genetic background of these associations is not thoroughly investigated, we aimed to analyze it in a longitudinal twin cohort...
  54. pmc Trends in breast cancer mortality in Sweden before and after implementation of mammography screening
    Jari Haukka
    Faculty of Medicine, Department of Public Health, University of Helsinki, Helsinki, Finland
    PLoS ONE 6:e22422. 2011
    ....
  55. doi request reprint A randomized clinical trial of histamine 2 receptor antagonism in treatment-resistant schizophrenia
    Katarina Meskanen
    University of Helsinki, Department of Psychiatry and Helsinki University Central Hospital, Helsinki, Finland
    J Clin Psychopharmacol 33:472-8. 2013
    ..This is the first placebo-controlled, randomized clinical trial showing a beneficial effect of histamine H2 antagonism in schizophrenia. H2 receptor antagonism may provide a new alternative for the treatment of schizophrenia...
  56. doi request reprint Description of long-term polypharmacy among schizophrenia outpatients
    Jaana T Suokas
    Department of Mental Health and Alcohol Research, National Institute for Health and Welfare, Helsinki, Finland
    Soc Psychiatry Psychiatr Epidemiol 48:631-8. 2013
    ..This large nationwide study describes the prevalence and predictors of long-term antipsychotic polypharmacy among patients with schizophrenia...
  57. doi request reprint Prevalence and natural course of craniocervical junction anomalies during growth in patients with osteogenesis imperfecta
    Heidi Arponen
    Department of Orthodontics, Institute of Dentistry, University of Helsinki, Helsinki, Finland
    J Bone Miner Res 27:1142-9. 2012
    ..A higher risk of having any of the pathological conditions was associated with a lower height Z-score. Careful follow-up of cranial base anomalies particularly in subjects with OI and severe growth failure is warranted...
  58. ncbi request reprint Heritability and number of quantitative trait loci of neurocognitive functions in families with schizophrenia
    Annamari Tuulio-Henriksson
    Department of Mental Health and Alcohol Research, National Public Health Institute of Finland, Helsinki
    Am J Med Genet 114:483-90. 2002
    ..Our results suggest that neurocognitive measures, particularly working memory, may provide valid quantitative phenotypic traits for linkage analyses searching predisposing genes for schizophrenia...
  59. doi request reprint Nocturia frequency, bother, and quality of life: how often is too often? A population-based study in Finland
    Kari A O Tikkinen
    Department of Urology, Helsinki University Central Hospital, Helsinki, Finland
    Eur Urol 57:488-96. 2010
    ..Nocturia (ie, waking at night to void) is common and disrupts sleep. Traditionally, one nightly episode has been regarded as clinically meaningless, yet the justification for this belief remains weak...
  60. ncbi request reprint Premorbid intellectual functioning in bipolar disorder and schizophrenia: results from a cohort study of male conscripts
    Jari Tiihonen
    Department of Forensic Psychiatry, University of Kuopio, Niuvanniemi Hospital, FIN 70240 Kuopio, Finland
    Am J Psychiatry 162:1904-10. 2005
    ..In this study, premorbid intellectual ability was investigated in individuals with bipolar disorder, schizophrenia, or other psychoses...
  61. ncbi request reprint Early onset of schizophrenia
    Jari Haukka
    Am J Psychiatry 159:322. 2002
  62. pmc Family-based clusters of cognitive test performance in familial schizophrenia
    Fabian Hoti
    Department of Mathematical Sciences, University of Oulu, Finland
    BMC Psychiatry 4:20. 2004
    ..The aim of the study was to detect family clusters with similar cognitive test performance...
  63. pmc Effectiveness of antipsychotic treatments in a nationwide cohort of patients in community care after first hospitalisation due to schizophrenia and schizoaffective disorder: observational follow-up study
    Jari Tiihonen
    Department of Forensic Psychiatry, University of Kuopio, Niuvanniemi Hospital, FIN 70240 Kuopio, Finland
    BMJ 333:224. 2006
    ..To study the association between prescribed antipsychotic drugs and outcome in schizophrenia or schizoaffective disorder in the community...
  64. ncbi request reprint Antidepressants and the risk of suicide, attempted suicide, and overall mortality in a nationwide cohort
    Jari Tiihonen
    Department of Forensic Psychiatry, University of Kuopio and Niuvanniemi Hospital, Kuopio University Hospital, Kuopio, Finland
    Arch Gen Psychiatry 63:1358-67. 2006
    ..It is unknown if antidepressant treatment is associated with either increased or decreased risk of suicide...
  65. ncbi request reprint [Suicide mortality in Finland during 1979-2001]
    Timo Partonen
    Kansanterveyslaitos, mielenterveyden ja alkoholitutkimuksen osasto Mannerheimintie 166, 00300 Helsinki
    Duodecim 119:1827-34. 2003
  66. ncbi request reprint A comparison of aripiprazole, methylphenidate, and placebo for amphetamine dependence
    Jari Tiihonen
    Department of Forensic Psychiatry, University of Kuopio, and the Department of Psychiatry, Helsinki University Hospital, Finland
    Am J Psychiatry 164:160-2. 2007
    ..To date, evidence on the effectiveness of psychosocial treatments has remained modest, and no pharmacotherapy has proven effective for amphetamine dependence...