Research Topics
| Valma HarjutsaloSummaryAffiliation: National Public Health Institute Country: Finland Publications
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Detail Information
Publications
Population-based assessment of familial clustering of diabetic nephropathy in type 1 diabetesValma Harjutsalo
National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
Diabetes 53:2449-54. 2004..Although the majority of sibpairs with type 1 diabetes are discordant for DN, its presence in one sibling doubles the risk for the other diabetic siblings...
Cumulative incidence of type 1 diabetes in 10,168 siblings of Finnish young-onset type 1 diabetic patientsValma Harjutsalo
Diabetes and Genetic Epidemiology Unit, Department of Epidemiology and Health Promotion, National Public Health Institute, Mannerheimintie 166, FIN 00300, Helsinki, Finland
Diabetes 54:563-9. 2005..This large prospective family study of type 1 diabetes in siblings of childhood-onset diabetic patients provides reliable empirical estimates for the sibling recurrence risk...
Differential transmission of type 1 diabetes from diabetic fathers and mothers to their offspringValma Harjutsalo
National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
Diabetes 55:1517-24. 2006..In the multivariate analyses, statistically significant predictors of type 1 diabetes in the offspring were male sex of the diabetic parent, young age at diagnosis in the male parent, and the more recent year of birth of the offspring...
Time trends in the incidence of type 1 diabetes in Finnish children: a cohort studyValma Harjutsalo
Diabetes Unit, Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
Lancet 371:1777-82. 2008..Our aim was to assess the temporal trend in type 1 diabetes incidence since 2000 in Finnish children aged younger than 15 years and to predict the number of cases of type 1 diabetes in the future...
Decline in the cumulative incidence of severe diabetic retinopathy in patients with type 1 diabetesJanne P Kytö
Department of Ophthalmology, Helsinki University Central Hospital, Helsinki, Finland
Diabetes Care 34:2005-7. 2011..To determine if the cumulative incidence of severe retinopathy in patients with type 1 diabetes has changed...
Menopause in women with type 1 diabetesLena Sjöberg
Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki, Finland
Menopause 18:158-63. 2011..Our objective was to study age at menopause and the factors associated with it in a large population-based group of Finnish women with childhood-onset type 1 diabetes...
Age at onset of type 1 diabetes in parents and recurrence risk in offspringValma Harjutsalo
Folkhalsan Institute of Genetics, Folkhälsan Research Centre, Biomedicum Helsinki, Helsinki, Finland
Diabetes 59:210-4. 2010....
Genetic random effects model for family data with long-term survivors: analysis of diabetic nephropathy in type 1 diabetesJanne Pitkäniemi
Department of Public Health, University of Helsinki, Helsinki, Finland
Genet Epidemiol 31:697-708. 2007..According to the variance components estimated a substantial familial variation in the susceptibility to DN exist among families, while time to DN is less influenced by shared familial factors...
Time trends in mortality in patients with type 1 diabetes: nationwide population based cohort studyValma Harjutsalo
Folkhalsan Institute of Genetics, Folkhälsan Research Centre, Biomedicum Helsinki, Haartmaninkatu 8, PO Box 63, FIN 00014, Helsinki, Finland
BMJ 343:d5364. 2011..To examine short and long term time trends in mortality among patients with early onset (age 0-14 years) and late onset (15-29 years) type 1 diabetes and causes of deaths over time...
Age at onset and the risk of proliferative retinopathy in type 1 diabetesKustaa Hietala
Folkhalsan Institute of Genetics, Folkhalsan Research Center, Biomedicum Helsinki, Helsinki, Finland
Diabetes Care 33:1315-9. 2010..Age at onset of type 1 diabetes influences the risk of microvascular complications. However, the long-term risk of proliferative retinopathy within the wide spectrum of age at onset of type 1 diabetes is less well known...
Pulse pressure predicts incident cardiovascular disease but not diabetic nephropathy in patients with type 1 diabetes (The FinnDiane Study)Daniel Gordin
Folkhalsan Institute of Genetics, Folkhalsan Research Center, Biomedicum Helsinki, Helsinki, Finland
Diabetes Care 34:886-91. 2011..Furthermore, the role of PP as a predictor of diabetic nephropathy is not known. Therefore, we prospectively investigated the associations between PP and these diabetes complications in patients with T1D...
New susceptibility loci associated with kidney disease in type 1 diabetesNiina Sandholm
Folkhalsan Institute of Genetics, Folkhalsan Research Center, Biomedicum Helsinki, Helsinki, Finland
PLoS Genet 8:e1002921. 2012..1 × 10(-7)), a gene with type 2 diabetes DN differential expression and in the same intron as a variant with cis-eQTL expression of ERBB4. All these detected associations represent new signals in the pathogenesis of DN...
Genetic and environmental effects on fasting and postchallenge plasma glucose and serum insulin values in Finnish twinsShuichi Katoh
Diabetes and Genetic Epidemiology Unit, National Public Health Institute, Helsinki, Finland
J Clin Endocrinol Metab 90:2642-7. 2005..81). In conclusion, additive genetic effects are important for the insulin secretion, whereas nonshared environmental effects contribute strongly to peripheral insulin resistance...
Type 1 diabetes and autism: is there a link?Valma Harjutsalo
Diabetes Care 29:484-5; discussion 485. 2006
