Valma Harjutsalo

Summary

Affiliation: National Public Health Institute
Country: Finland

Publications

  1. ncbi Population-based assessment of familial clustering of diabetic nephropathy in type 1 diabetes
    Valma Harjutsalo
    National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    Diabetes 53:2449-54. 2004
  2. ncbi Cumulative incidence of type 1 diabetes in 10,168 siblings of Finnish young-onset type 1 diabetic patients
    Valma Harjutsalo
    Diabetes and Genetic Epidemiology Unit, Department of Epidemiology and Health Promotion, National Public Health Institute, Mannerheimintie 166, FIN 00300, Helsinki, Finland
    Diabetes 54:563-9. 2005
  3. ncbi Differential transmission of type 1 diabetes from diabetic fathers and mothers to their offspring
    Valma Harjutsalo
    National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    Diabetes 55:1517-24. 2006
  4. doi Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study
    Valma Harjutsalo
    Diabetes Unit, Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
    Lancet 371:1777-82. 2008
  5. pmc Chromosome 2q31.1 associates with ESRD in women with type 1 diabetes
    Niina Sandholm
    Folkhalsan Institute of Genetics, Folkhalsan Research Center, Helsinki, Finland
    J Am Soc Nephrol 24:1537-43. 2013
  6. pmc Decline in the cumulative incidence of severe diabetic retinopathy in patients with type 1 diabetes
    Janne P Kytö
    Department of Ophthalmology, Helsinki University Central Hospital, Helsinki, Finland
    Diabetes Care 34:2005-7. 2011
  7. doi Menopause in women with type 1 diabetes
    Lena Sjöberg
    Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki, Finland
    Menopause 18:158-63. 2011
  8. pmc Age at onset of type 1 diabetes in parents and recurrence risk in offspring
    Valma Harjutsalo
    Folkhalsan Institute of Genetics, Folkhälsan Research Centre, Biomedicum Helsinki, Helsinki, Finland
    Diabetes 59:210-4. 2010
  9. ncbi Genome-wide association study of urinary albumin excretion rate in patients with type 1 diabetes
    Niina Sandholm
    Folkhalsan Institute of Genetics, Folkhalsan Research Center, Biomedicum Helsinki, Helsinki, Finland
    Diabetologia 57:1143-53. 2014
  10. pmc Osteoprotegerin is an independent predictor of vascular events in Finnish adults with type 1 diabetes
    Daniel Gordin
    Division of Nephrology, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Diabetes Care 36:1827-33. 2013

Collaborators

Detail Information

Publications18

  1. ncbi Population-based assessment of familial clustering of diabetic nephropathy in type 1 diabetes
    Valma Harjutsalo
    National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    Diabetes 53:2449-54. 2004
    ..Although the majority of sibpairs with type 1 diabetes are discordant for DN, its presence in one sibling doubles the risk for the other diabetic siblings...
  2. ncbi Cumulative incidence of type 1 diabetes in 10,168 siblings of Finnish young-onset type 1 diabetic patients
    Valma Harjutsalo
    Diabetes and Genetic Epidemiology Unit, Department of Epidemiology and Health Promotion, National Public Health Institute, Mannerheimintie 166, FIN 00300, Helsinki, Finland
    Diabetes 54:563-9. 2005
    ..This large prospective family study of type 1 diabetes in siblings of childhood-onset diabetic patients provides reliable empirical estimates for the sibling recurrence risk...
  3. ncbi Differential transmission of type 1 diabetes from diabetic fathers and mothers to their offspring
    Valma Harjutsalo
    National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    Diabetes 55:1517-24. 2006
    ..In the multivariate analyses, statistically significant predictors of type 1 diabetes in the offspring were male sex of the diabetic parent, young age at diagnosis in the male parent, and the more recent year of birth of the offspring...
  4. doi Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study
    Valma Harjutsalo
    Diabetes Unit, Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
    Lancet 371:1777-82. 2008
    ..Our aim was to assess the temporal trend in type 1 diabetes incidence since 2000 in Finnish children aged younger than 15 years and to predict the number of cases of type 1 diabetes in the future...
  5. pmc Chromosome 2q31.1 associates with ESRD in women with type 1 diabetes
    Niina Sandholm
    Folkhalsan Institute of Genetics, Folkhalsan Research Center, Helsinki, Finland
    J Am Soc Nephrol 24:1537-43. 2013
    ..004). Overall, these results suggest that rs4972593 is a sex-specific genetic variant associated with ESRD in patients with type 1 diabetes and may underlie the sex-specific protection against ESRD. ..
  6. pmc Decline in the cumulative incidence of severe diabetic retinopathy in patients with type 1 diabetes
    Janne P Kytö
    Department of Ophthalmology, Helsinki University Central Hospital, Helsinki, Finland
    Diabetes Care 34:2005-7. 2011
    ..To determine if the cumulative incidence of severe retinopathy in patients with type 1 diabetes has changed...
  7. doi Menopause in women with type 1 diabetes
    Lena Sjöberg
    Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki, Finland
    Menopause 18:158-63. 2011
    ..Our objective was to study age at menopause and the factors associated with it in a large population-based group of Finnish women with childhood-onset type 1 diabetes...
  8. pmc Age at onset of type 1 diabetes in parents and recurrence risk in offspring
    Valma Harjutsalo
    Folkhalsan Institute of Genetics, Folkhälsan Research Centre, Biomedicum Helsinki, Helsinki, Finland
    Diabetes 59:210-4. 2010
    ....
  9. ncbi Genome-wide association study of urinary albumin excretion rate in patients with type 1 diabetes
    Niina Sandholm
    Folkhalsan Institute of Genetics, Folkhalsan Research Center, Biomedicum Helsinki, Helsinki, Finland
    Diabetologia 57:1143-53. 2014
    ..Our aim was to estimate the heritability and to detect genetic variation associated with elevated AER in patients with type 1 diabetes...
  10. pmc Osteoprotegerin is an independent predictor of vascular events in Finnish adults with type 1 diabetes
    Daniel Gordin
    Division of Nephrology, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Diabetes Care 36:1827-33. 2013
    ..Osteoprotegerin (OPG) is involved in the process of vascular calcification. We investigated whether OPG is associated with the development and progression of diabetes complications in adults with type 1 diabetes (T1D)...
  11. ncbi Genetic random effects model for family data with long-term survivors: analysis of diabetic nephropathy in type 1 diabetes
    Janne Pitkäniemi
    Department of Public Health, University of Helsinki, Helsinki, Finland
    Genet Epidemiol 31:697-708. 2007
    ..According to the variance components estimated a substantial familial variation in the susceptibility to DN exist among families, while time to DN is less influenced by shared familial factors...
  12. pmc Time trends in mortality in patients with type 1 diabetes: nationwide population based cohort study
    Valma Harjutsalo
    Folkhalsan Institute of Genetics, Folkhälsan Research Centre, Biomedicum Helsinki, Haartmaninkatu 8, PO Box 63, FIN 00014, Helsinki, Finland
    BMJ 343:d5364. 2011
    ..To examine short and long term time trends in mortality among patients with early onset (age 0-14 years) and late onset (15-29 years) type 1 diabetes and causes of deaths over time...
  13. pmc Age at onset and the risk of proliferative retinopathy in type 1 diabetes
    Kustaa Hietala
    Folkhalsan Institute of Genetics, Folkhalsan Research Center, Biomedicum Helsinki, Helsinki, Finland
    Diabetes Care 33:1315-9. 2010
    ..Age at onset of type 1 diabetes influences the risk of microvascular complications. However, the long-term risk of proliferative retinopathy within the wide spectrum of age at onset of type 1 diabetes is less well known...
  14. pmc Pulse pressure predicts incident cardiovascular disease but not diabetic nephropathy in patients with type 1 diabetes (The FinnDiane Study)
    Daniel Gordin
    Folkhalsan Institute of Genetics, Folkhalsan Research Center, Biomedicum Helsinki, Helsinki, Finland
    Diabetes Care 34:886-91. 2011
    ..Furthermore, the role of PP as a predictor of diabetic nephropathy is not known. Therefore, we prospectively investigated the associations between PP and these diabetes complications in patients with T1D...
  15. pmc New susceptibility loci associated with kidney disease in type 1 diabetes
    Niina Sandholm
    Folkhalsan Institute of Genetics, Folkhalsan Research Center, Biomedicum Helsinki, Helsinki, Finland
    PLoS Genet 8:e1002921. 2012
    ..1 × 10(-7)), a gene with type 2 diabetes DN differential expression and in the same intron as a variant with cis-eQTL expression of ERBB4. All these detected associations represent new signals in the pathogenesis of DN...
  16. ncbi Genetic and environmental effects on fasting and postchallenge plasma glucose and serum insulin values in Finnish twins
    Shuichi Katoh
    Diabetes and Genetic Epidemiology Unit, National Public Health Institute, Helsinki, Finland
    J Clin Endocrinol Metab 90:2642-7. 2005
    ..81). In conclusion, additive genetic effects are important for the insulin secretion, whereas nonshared environmental effects contribute strongly to peripheral insulin resistance...
  17. ncbi Epidemiology and risk factors for diabetic kidney disease
    Valma Harjutsalo
    Division of Nephrology, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland Folkhälsan Institute of Genetics, Folkhalsan Research Center, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland National Institute for Health and Welfare, Diabetes Prevention Unit, Helsinki, Finland Diabetes and Obesity Research Program, Research Program s Unit, University of Helsinki, Helsinki, Finland Baker IDI Heart and Diabetes Institute, Melbourne, Australia
    Adv Chronic Kidney Dis 21:260-6. 2014
    ..Efficient management of these modifiable risk factors may improve the prognosis of diabetic patients at risk of DKD. ..
  18. ncbi Type 1 diabetes and autism: is there a link?
    Valma Harjutsalo
    Diabetes Care 29:484-5; discussion 485. 2006