Pasi Hakulinen

Summary

Affiliation: National Public Health Institute
Country: Finland

Publications

  1. ncbi Potent inhibition of gap junctional intercellular communication by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in BALB/c 3T3 cells
    Pasi Hakulinen
    National Public Health Institute, Laboratory of Toxicology, P O Box 95, Kuopio FIN 70701, Finland
    Toxicol Lett 151:439-49. 2004
  2. ncbi Altered expression of connexin43 in the inhibition of gap junctional intercellular communication by chlorohydroxyfuranones in WB-F344 rat liver epithelial cells
    Pasi Hakulinen
    National Public Health Institute, Laboratory of Toxicology, P O B 95, FI 70701 Kuopio, Finland
    Toxicol Appl Pharmacol 212:146-55. 2006
  3. ncbi Expression of p53 and p21 Ki-ras proteins in rat thyroid gland tumors induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX)
    Pasi Hakulinen
    Laboratory of Toxicology, National Public Health Institute, Kuopio, Finland
    Anticancer Res 22:703-6. 2002

Detail Information

Publications3

  1. ncbi Potent inhibition of gap junctional intercellular communication by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in BALB/c 3T3 cells
    Pasi Hakulinen
    National Public Health Institute, Laboratory of Toxicology, P O Box 95, Kuopio FIN 70701, Finland
    Toxicol Lett 151:439-49. 2004
    ..MCA also has a specific potential to inhibit GJIC whereas MCF and CMCF affected GJIC at concentrations, similar to those evoking genotoxicity in vitro...
  2. ncbi Altered expression of connexin43 in the inhibition of gap junctional intercellular communication by chlorohydroxyfuranones in WB-F344 rat liver epithelial cells
    Pasi Hakulinen
    National Public Health Institute, Laboratory of Toxicology, P O B 95, FI 70701 Kuopio, Finland
    Toxicol Appl Pharmacol 212:146-55. 2006
    ..The results indicate that all the studied CHFs inhibit GJIC in WB-F344 cells by altering Cx43 expression...
  3. ncbi Expression of p53 and p21 Ki-ras proteins in rat thyroid gland tumors induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX)
    Pasi Hakulinen
    Laboratory of Toxicology, National Public Health Institute, Kuopio, Finland
    Anticancer Res 22:703-6. 2002
    ..No expression of p21 Ki-ras was observed in any of the samples. CONCLUSION: These data indicate that p53 and Ki-ras proteins are not overexpressed in the MX-induced thyroid tumors in rats...