J G Eriksson

Summary

Affiliation: National Public Health Institute
Country: Finland

Publications

  1. pmc Quality of life and metabolic status in mildly depressed women with type 2 diabetes treated with paroxetine: a single-blind randomised placebo controlled trial
    Maria Paile-Hyvärinen
    Department of Psychiatry, University of Helsinki, Lapinlahti Hospital, P O Box 320, FIN 00029 HUCH, Helsinki, Finland
    BMC Fam Pract 4:7. 2003
  2. ncbi request reprint The effect of coenzyme Q10 administration on metabolic control in patients with type 2 diabetes mellitus
    J G Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Helsinki, Finland
    Biofactors 9:315-8. 1999
  3. ncbi request reprint Childhood growth and coronary heart disease in later life
    Johan G Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Helsinki, Finland
    Ann Med 34:157-61. 2002
  4. ncbi request reprint Early growth and adult health outcomes--lessons learned from the Helsinki Birth Cohort Study
    Johan G Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, Mannerheimintie 166, 00300 Helsinki, Finland
    Matern Child Nutr 1:149-54. 2005
  5. ncbi request reprint Early adiposity rebound in childhood and risk of Type 2 diabetes in adult life
    J G Eriksson
    Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland
    Diabetologia 46:190-4. 2003
  6. ncbi request reprint Long-term beneficial effects of glipizide treatment on glucose tolerance in subjects with impaired glucose tolerance
    J G Eriksson
    Diabetes and Genetic Epidemiology Unit, Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
    J Intern Med 259:553-60. 2006
  7. ncbi request reprint Obesity from cradle to grave
    J Eriksson
    Department of Epidemiology and Health Promotion, National Public Health Institute, Diabetes and Genetic Epidemiology Unit, Mannerheimintie, Helsinki, Finland
    Int J Obes Relat Metab Disord 27:722-7. 2003
  8. ncbi request reprint The effects of the Pro12Ala polymorphism of the PPARgamma-2 gene on lipid metabolism interact with body size at birth
    J Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, Helsinki, Finland
    Clin Genet 64:366-70. 2003
  9. ncbi request reprint Exercise protects against glucose intolerance in individuals with a small body size at birth
    Johan G Eriksson
    Department of Epidemiology and Health Promotion, National Public Health Institute, FIN 00300 Helsinki, Finland
    Prev Med 39:164-7. 2004
  10. ncbi request reprint The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth
    Johan G Eriksson
    Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    Diabetes 51:2321-4. 2002

Collaborators

Detail Information

Publications92

  1. pmc Quality of life and metabolic status in mildly depressed women with type 2 diabetes treated with paroxetine: a single-blind randomised placebo controlled trial
    Maria Paile-Hyvärinen
    Department of Psychiatry, University of Helsinki, Lapinlahti Hospital, P O Box 320, FIN 00029 HUCH, Helsinki, Finland
    BMC Fam Pract 4:7. 2003
    ..The aim of this trial was to evaluate the effect of the antidepressant paroxetine on metabolic control, quality of life and mental well-being in mildly depressed women with type 2 diabetes...
  2. ncbi request reprint The effect of coenzyme Q10 administration on metabolic control in patients with type 2 diabetes mellitus
    J G Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Helsinki, Finland
    Biofactors 9:315-8. 1999
    ..The treatment was well tolerated and did not interfere with glycemic control, therefore CoQ10 may be used as adjunctive therapy in patients with associated cardiovascular diseases...
  3. ncbi request reprint Childhood growth and coronary heart disease in later life
    Johan G Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Helsinki, Finland
    Ann Med 34:157-61. 2002
    ..Biological programming - the process whereby a stimulus during critical periods of development has long lasting or lifelong effects on metabolism - is proposed to mediate the effects between early growth and adult diseases...
  4. ncbi request reprint Early growth and adult health outcomes--lessons learned from the Helsinki Birth Cohort Study
    Johan G Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, Mannerheimintie 166, 00300 Helsinki, Finland
    Matern Child Nutr 1:149-54. 2005
    ..Most data suggest that the development of many non-communicable diseases involve a number of interactions including genetic ones. Therefore these diseases can best be focused upon from a life cycle perspective...
  5. ncbi request reprint Early adiposity rebound in childhood and risk of Type 2 diabetes in adult life
    J G Eriksson
    Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland
    Diabetologia 46:190-4. 2003
    ..Type 2 diabetes is associated with a small body size at birth and a high BMI in adult life. The aim of our study was to assess the associations between Type 2 diabetes and birth size, infant growth and age at adiposity rebound...
  6. ncbi request reprint Long-term beneficial effects of glipizide treatment on glucose tolerance in subjects with impaired glucose tolerance
    J G Eriksson
    Diabetes and Genetic Epidemiology Unit, Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
    J Intern Med 259:553-60. 2006
    ..To assess the efficacy and long-term effects of glipizide treatment on glucose and insulin metabolism in individuals with impaired glucose tolerance (IGT)...
  7. ncbi request reprint Obesity from cradle to grave
    J Eriksson
    Department of Epidemiology and Health Promotion, National Public Health Institute, Diabetes and Genetic Epidemiology Unit, Mannerheimintie, Helsinki, Finland
    Int J Obes Relat Metab Disord 27:722-7. 2003
    ..Obesity is known to track from early life into adult life...
  8. ncbi request reprint The effects of the Pro12Ala polymorphism of the PPARgamma-2 gene on lipid metabolism interact with body size at birth
    J Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, Helsinki, Finland
    Clin Genet 64:366-70. 2003
    ..These interactions between the effects of the PPARgamma-2 gene on adult traits and the effects of birth weight may be interpreted as examples of gene-environmental interactions, which underlie plasticity during development...
  9. ncbi request reprint Exercise protects against glucose intolerance in individuals with a small body size at birth
    Johan G Eriksson
    Department of Epidemiology and Health Promotion, National Public Health Institute, FIN 00300 Helsinki, Finland
    Prev Med 39:164-7. 2004
    ..We investigated whether regular exercise is related to lower rates of glucose intolerance in individuals with a small body size at birth and whether birth size affects exercise habits in adulthood...
  10. ncbi request reprint The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth
    Johan G Eriksson
    Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    Diabetes 51:2321-4. 2002
    ..We suggest that these findings reflect gene-environment interaction...
  11. ncbi request reprint [Low birth weight and social factors affect the risk of coronary disease]
    Johan Eriksson
    Folkhälsoinstitutet, Helsingfors
    Lakartidningen 99:1209. 2002
  12. ncbi request reprint Size at birth, fat-free mass and resting metabolic rate in adult life
    J Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, Helsinki, Finland
    Horm Metab Res 34:72-6. 2002
    ..The muscle tissue of people who had a lower birth weight is more metabolically active than those with a higher birth weight. This may protect them from the increased risk of obesity associated with low fat-free mass...
  13. ncbi request reprint Exercise and the treatment of type 2 diabetes mellitus. An update
    J G Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Helsinki, Finland
    Sports Med 27:381-91. 1999
    ..The vast majority of patients with type 2 diabetes mellitus can undertake an individualised exercise programme without significantly increased risks of complications...
  14. ncbi request reprint Leptin concentrations and their relation to body fat distribution and weight loss--a prospective study in individuals with impaired glucose tolerance. DPS-study group
    J Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Helsinki, Finland
    Horm Metab Res 31:616-9. 1999
    ..Body fat distribution was also of importance, especially among females. Gender associated differences in leptin concentrations appear to be largely influenced by gender differences in body fat distribution...
  15. pmc Early growth and coronary heart disease in later life: longitudinal study
    J G Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    BMJ 322:949-53. 2001
    ..To determine how growth during infancy and childhood modifies the increased risk of coronary heart disease associated with small body size at birth...
  16. ncbi request reprint Size at birth, childhood growth and obesity in adult life
    J Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, Helsinki, Finland
    Int J Obes Relat Metab Disord 25:735-40. 2001
    ..Several studies have shown tracking of obesity from childhood to adult life. People who develop obesity in adult life may therefore have had a particular path of growth from birth through childhood...
  17. ncbi request reprint Effects of size at birth and childhood growth on the insulin resistance syndrome in elderly individuals
    J G Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Helsinki, Finland
    Diabetologia 45:342-8. 2002
    ....
  18. doi request reprint Childhood growth and cardiovascular reactivity to psychological stressors in late adulthood
    K Feldt
    Departments of Psychology, University of Helsinki, Helsinki, Finland
    J Intern Med 264:72-82. 2008
    ..We studied whether CV reactivity, a predictor of CV disease risk, is associated with childhood growth trajectories...
  19. ncbi request reprint Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
    J Tuomilehto
    Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
    N Engl J Med 344:1343-50. 2001
    ..Whether type 2 diabetes can be prevented by interventions that affect the lifestyles of subjects at high risk for the disease is not known...
  20. ncbi request reprint Patterns of growth among children who later develop type 2 diabetes or its risk factors
    J G Eriksson
    National Public Health Institute, Helsinki, Finland
    Diabetologia 49:2853-8. 2006
    ..We studied fetal and childhood growth patterns that are associated with IGT and type 2 diabetes in adult life...
  21. doi request reprint Role of childhood growth on the risk of metabolic syndrome in obese men and women
    M K Salonen
    Department of Chronic Disease Prevention, National Institute of Health and Welfare, Mannerheimintie 166, 00300 Helsinki, Finland
    Diabetes Metab 35:94-100. 2009
    ..Although obesity is the key characteristic of the metabolic syndrome, not all obese individuals develop the syndrome. Our aim was to identify characteristics of early growth that protect these individuals from the metabolic syndrome...
  22. doi request reprint Body size at birth and cardiovascular response to and recovery from mental stress in children
    K Feldt
    Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland
    J Hum Hypertens 25:231-40. 2011
    ..This phenomenon may be important in linking smaller body size at birth to adult CV disease...
  23. ncbi request reprint Metabolic effects of metformin in patients with impaired glucose tolerance
    M Lehtovirta
    Department of Medicine, Helsinki University Hospital, Helsinki, Finland
    Diabet Med 18:578-83. 2001
    ..Obviously large multicentre studies are needed to establish whether these effects are sufficient to prevent progression to manifest Type 2 diabetes and associated cardiovascular morbidity and mortality. Diabet. Med. 18, 578-583 (2001)..
  24. doi request reprint Determinants for the effectiveness of lifestyle intervention in the Finnish Diabetes Prevention Study
    Jaana Lindström
    Diabetes Unit, Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
    Diabetes Care 31:857-62. 2008
    ..We investigated whether and to what extent risk factors for type 2 diabetes and other baseline characteristics of the study participants modified the effectiveness of the lifestyle intervention...
  25. doi request reprint Childhood BMI trajectories and the risk of developing young adult-onset diabetes
    N Lammi
    Diabetes Unit, Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Mannerheimintie 166, 00300, Helsinki, Finland
    Diabetologia 52:408-14. 2009
    ..The aim of this study was to examine the effects of childhood BMI growth dynamics on the risk of developing young adult-onset type 1 and type 2 diabetes...
  26. doi request reprint Childhood growth and future risk of the metabolic syndrome in normal-weight men and women
    M K Salonen
    Department of Chronic Disease Prevention, National Institute of Health and Welfare, Mannerheimintie 166, 00300 Helsinki, Finland
    Diabetes Metab 35:143-50. 2009
    ..The aim of this study was to examine the effects of early growth on the risk of developing the metabolic syndrome in normal-weight individuals...
  27. doi request reprint A family history of diabetes is associated with reduced physical fitness in the Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study
    B Isomaa
    Folkhälsan Genetic Institute, Helsinki, Finland
    Diabetologia 53:1709-13. 2010
    ..We studied the impact of a family history of type 2 diabetes on physical fitness, lifestyle factors and diabetes-related metabolic factors...
  28. ncbi request reprint Birth size, adult body composition and muscle strength in later life
    H Ylihärsilä
    Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
    Int J Obes (Lond) 31:1392-9. 2007
    ..We examined how birth weight was related to adult body size, body composition and grip strength...
  29. doi request reprint Depressive symptoms in adulthood and intrauterine exposure to pre-eclampsia: the Helsinki Birth Cohort Study
    S Tuovinen
    Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland
    BJOG 117:1236-42. 2010
    ..We studied whether pre-eclampsia predicts depressive symptoms in offspring...
  30. ncbi request reprint Prevalence of diabetes and impaired glucose regulation in 45- to 64-year-old individuals in three areas of Finland
    H Ylihärsilä
    Department of Epidemiology and Health Promotion, National Public Health Institute, 00300 Helsinki, Finland
    Diabet Med 22:88-91. 2005
    ..To determine the prevalence of diabetes mellitus (DM), impaired glucose tolerance (IGT) and impaired fasting glycaemia (IFG) and possible regional differences in Finnish adults aged between 45 and 64 years...
  31. doi request reprint Prenatal growth, postnatal growth and trait anxiety in late adulthood - the Helsinki Birth Cohort Study
    J Lahti
    Department of Psychology, University of Helsinki, Helsinki, Finland
    Acta Psychiatr Scand 121:227-35. 2010
    ..Trait anxiety may predispose to anxiety disorders and cardiovascular events. We tested whether prenatal growth or postnatal growth from birth to 11 years of age and in adulthood predict trait anxiety in late adulthood...
  32. ncbi request reprint Association of schizophrenia with low maternal body mass index, small size at birth, and thinness during childhood
    K Wahlbeck
    Department of Psychiatry, University of Helsinki, Lappviksvägen, PO Box 320, FIN 00029, Helsinki, Finland
    Arch Gen Psychiatry 58:48-52. 2001
    ..Nutritional factors in early life may contribute to the neurodevelopmental deficit in schizophrenia. This study explores the influence of maternal body size, size at birth, and childhood growth on future risk for schizophrenia...
  33. ncbi request reprint High-fibre, low-fat diet predicts long-term weight loss and decreased type 2 diabetes risk: the Finnish Diabetes Prevention Study
    J Lindstrom
    Diabetes and Genetic Epidemiology Unit, Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
    Diabetologia 49:912-20. 2006
    ..The aim of this study was to investigate the association of dietary macronutrient composition and energy density with the change in body weight and waist circumference and diabetes incidence in the Finnish Diabetes Prevention Study...
  34. doi request reprint Neurocognitive abilities in young adults with very low birth weight
    R Pyhälä
    Institute of Behavioral Sciences, University of Helsinki, Helsinki, Finland
    Neurology 77:2052-60. 2011
    ....
  35. ncbi request reprint The effect of birth order and parental age on the risk of type 1 and 2 diabetes among young adults
    N Lammi
    Diabetes Unit, Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
    Diabetologia 50:2433-8. 2007
    ..The aim of this study was to examine the effects of birth order and parental age on the risk of type 1 and type 2 diabetes among Finnish individuals aged 15-39 years...
  36. ncbi request reprint Early growth, and coronary heart disease and type 2 diabetes: experiences from the Helsinki Birth Cohort Studies
    J G Eriksson
    Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, National Public Health Institute, Helsinki, Finland
    Int J Obes (Lond) 30:S18-22. 2006
    ..To get a better understanding of the patterns of growth affecting adult health outcomes, a life-course approach to the development of chronic diseases needs to be taken...
  37. ncbi request reprint Epidemiology, genes and the environment: lessons learned from the Helsinki Birth Cohort Study
    J G Eriksson
    Department of Public Health, University of Helsinki, Helsinki, Finland
    J Intern Med 261:418-25. 2007
    ..This overview will primarily focus upon findings from the Helsinki Birth Cohort Study consisting of 15846 subjects born 1924-1944 on whom growth data and information on adult health are available...
  38. doi request reprint Early life stress and blood pressure levels in late adulthood
    H Alastalo
    Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland
    J Hum Hypertens 27:90-4. 2013
    ..This could be due to early hormonal and metabolic programming, during plastic periods in early life, influencing blood pressure levels in adult life...
  39. ncbi request reprint A high incidence of type 1 diabetes and an alarming increase in the incidence of type 2 diabetes among young adults in Finland between 1992 and 1996
    N Lammi
    Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Mannerheimintie 166, 00300, Helsinki, Finland
    Diabetologia 50:1393-400. 2007
    ..The aim of this study was to examine the incidence and trends of type 1 and type 2 diabetes in the 15-39 year-old population between 1992 and 1996 in Finland...
  40. doi request reprint Improved lifestyle and decreased diabetes risk over 13 years: long-term follow-up of the randomised Finnish Diabetes Prevention Study (DPS)
    J Lindstrom
    Diabetes Prevention Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Hellsinki, Finland
    Diabetologia 56:284-93. 2013
    ..This study aimed to determine whether lifestyle intervention lasting for 4 years affected diabetes incidence, body weight, glycaemia or lifestyle over 13 years among individuals at high risk of type 2 diabetes...
  41. ncbi request reprint Cardiovascular reactivity to psychological stressors in late adulthood is predicted by gestational age at birth
    K Feldt
    Department of Psychology, University of Helsinki, Helsinki, Finland
    J Hum Hypertens 21:401-10. 2007
    ....
  42. ncbi request reprint Occupational, commuting, and leisure-time physical activity in relation to risk for Type 2 diabetes in middle-aged Finnish men and women
    G Hu
    Diabetes and Genetic Epidemiology Unit, Department of Epidemiology and Health Promotion, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland
    Diabetologia 46:322-9. 2003
    ..This study is to examine the relationship of occupational, commuting and leisure-time physical activity with the incidence of Type 2 diabetes...
  43. doi request reprint Leukocyte telomere length and its relation to food and nutrient intake in an elderly population
    A M K Tiainen
    Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland
    Eur J Clin Nutr 66:1290-4. 2012
    ..We hypothesized that intakes of fruits and vegetables would be positively associated with LTL and that intakes of fats, and especially saturated fatty acids (SFAs), would be negatively associated with LTL...
  44. ncbi request reprint SNPs in PPARG associate with type 2 diabetes and interact with physical activity
    Tuomas O Kilpeläinen
    Institute of Biomedicine, Physiology, University of Kuopio, Kuopio, Finland
    Med Sci Sports Exerc 40:25-33. 2008
    ....
  45. ncbi request reprint A possible link between the pubertal growth of girls and breast cancer in their daughters
    David J P Barker
    Heart Research Center, Oregon Health and Science University, Portland, OR, USA
    Am J Hum Biol 20:127-31. 2008
    ....
  46. ncbi request reprint Depression and its association with diabetes, cardiovascular disease, and birth weight
    Maria Paile-Hyvärinen
    National Public Health Institute, Department of Health Promotion and Chronic Disease Prevention, Diabetes Unit, Mannerheimintie 166, 00300 Helsinki, Finland
    Ann Med 39:634-40. 2007
    ..Diabetes increases the risk for depression...
  47. ncbi request reprint Body size at birth predicts hypothalamic-pituitary-adrenal axis response to psychosocial stress at age 60 to 70 years
    Eero Kajantie
    National Public Health Institute, Department of Health Promotion and Chronic Disease Prevention, Mannerheimintie 166, 00300 Helsinki, Finland
    J Clin Endocrinol Metab 92:4094-100. 2007
    ..Studies in humans and animals have suggested intrauterine programming of hypothalamic-pituitary-adrenal axis (HPAA) function as an important mechanism in linking fetal life conditions with adult disease...
  48. doi request reprint Effect of lifestyle intervention on the occurrence of metabolic syndrome and its components in the Finnish Diabetes Prevention Study
    Pirjo Ilanne-Parikka
    Diabetes Center, Finnish Diabetes Association, Tampere, Finland
    Diabetes Care 31:805-7. 2008
    ..The aim of this secondary analysis of the Finnish Diabetes Prevention Study was to assess the effects of lifestyle intervention on metabolic syndrome and its components...
  49. doi request reprint The role of genes in growth and later health
    Johan G Eriksson
    University of Helsinki and National Public Health Institute, Helsinki, Finland
    Nestle Nutr Workshop Ser Pediatr Program 61:69-77. 2008
    ..We propose that these findings reflect gene-early environment interactions and can be attributed to the phenomenon of developmental plasticity...
  50. doi request reprint Very low birth weight and behavioral symptoms of attention deficit hyperactivity disorder in young adulthood: the Helsinki study of very-low-birth-weight adults
    Sonja Strang-Karlsson
    Hospital for Children and Adolescents, Biomedicum 2, Tukholmankatu 8C, Helsinki University Central Hospital, PO Box 705, FI 00029 Helsinki, Finland
    Am J Psychiatry 165:1345-53. 2008
    ....
  51. doi request reprint Body size at birth and socio-economic status in childhood: implications for Cloninger's psychobiological model of temperament at age 60
    Jari Lahti
    Department of Psychology, University of Helsinki, Helsinki, Finland
    Psychiatry Res 160:167-74. 2008
    ....
  52. ncbi request reprint Body mass index during childhood and adult body composition in men and women aged 56-70 y
    Hilkka Ylihärsilä
    National Public Health Institute, Department of Epidemiology and Health Promotion, Helsinki, Finland
    Am J Clin Nutr 87:1769-75. 2008
    ..The relation between the change in body mass index (BMI) through childhood and body composition in adult life is important because body composition is known to affect adult health...
  53. doi request reprint Prenatal and postnatal growth and cognitive abilities at 56 months of age: a longitudinal study of infants born at term
    Kati Heinonen
    Department of Psychology, PO Box 9, FI 00014 University of Helsinki, Helsinki, Finland
    Pediatrics 121:e1325-33. 2008
    ....
  54. doi request reprint Geographical variation of medicated parkinsonism in Finland during 1995 to 2000
    Aki S Havulinna
    Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
    Mov Disord 23:1024-31. 2008
    ....
  55. doi request reprint Infant growth and hostility in adult life
    Katri Rikkönen
    Department of Psychology, University of Helsinki, P O Box 9 Siltavuorenpenger 20 D, 00014 University of Helsinki, Finland
    Psychosom Med 70:306-13. 2008
    ..A common origin in suboptimal fetal and early postnatal life may lie beneath. This study tested whether prenatal and postnatal growth predicts hostility in adult life...
  56. doi request reprint Growth before 2 years of age and serum lipids 60 years later: the Helsinki Birth Cohort study
    Eero Kajantie
    The National Public Health Institute, Helsinki, Finland
    Int J Epidemiol 37:280-9. 2008
    ..We tested the hypothesis that this path of growth is associated with an atherogenic lipid profile in later life...
  57. doi request reprint Reproductive traits following a parent-child separation trauma during childhood: a natural experiment during World War II
    Anu Katriina Pesonen
    Department of Psychology, University of Helsinki, Helsinki, Finland
    Am J Hum Biol 20:345-51. 2008
    ..The implications are relevant to the 9.2 million child refugees living throughout the world today...
  58. doi request reprint Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention
    Tuomas O Kilpeläinen
    Institute of Biomedicine, Physiology, University of Kuopio, Kuopio 70211, Finland
    Metabolism 57:428-36. 2008
    ..In conclusion, genetic variation may modify the magnitude of the beneficial effects of PA on characteristics of the metabolic syndrome in persons with IGT...
  59. ncbi request reprint Maternal and social origins of hypertension
    David J P Barker
    Heart Research Center, Oregon Health and Science University, Portland, USA
    Hypertension 50:565-71. 2007
    ....
  60. pmc Quality of life and metabolic status in mildly depressed patients with type 2 diabetes treated with paroxetine: a double-blind randomised placebo controlled 6-month trial
    Maria Paile-Hyvärinen
    National Public Health Institute, Mannerheimintie, Helsinki, Finland
    BMC Fam Pract 8:34. 2007
    ..The aim of this investigator-initiated trial was to evaluate the effect of the antidepressant paroxetine on quality of life, metabolic control, and mental well-being in mildly depressed diabetics aged 50-70 years...
  61. ncbi request reprint Systemic immune mediators and lifestyle changes in the prevention of type 2 diabetes: results from the Finnish Diabetes Prevention Study
    Christian Herder
    German Diabetes Clinic, German Diabetes Center, Leibniz Center at Heinrich Heine University Düsseldorf, Auf m Hennekamp 65, 40225 Dusseldorf, Germany
    Diabetes 55:2340-6. 2006
    ..088). Thus, systemic concentrations of immune mediators appear to be associated with the progression to type 2 diabetes and the prevention of type 2 diabetes by lifestyle changes...
  62. ncbi request reprint Trajectories of growth among children who have coronary events as adults
    David J P Barker
    Developmental Origins of Health and Disease Division, University of Southampton, Southampton General Hospital, Southampton, United Kingdom
    N Engl J Med 353:1802-9. 2005
    ..Low birth weight is a risk factor for coronary heart disease. It is uncertain how postnatal growth affects disease risk...
  63. ncbi request reprint Size at birth as a predictor of mortality in adulthood: a follow-up of 350 000 person-years
    Eero Kajantie
    National Public Health Institute, Helsinki, Finland
    Int J Epidemiol 34:655-63. 2005
    ..Our aim was to study the relationship between small size at birth and all-cause and non-cardiovascular mortality, which has been poorly documented...
  64. ncbi request reprint Physical activity in the prevention of type 2 diabetes: the Finnish diabetes prevention study
    David E Laaksonen
    Department of Clinical Nutrition and Food and Health Research Center, University of Kuopio, P O Box 1627, Kuopio, Finland
    Diabetes 54:158-65. 2005
    ..34, 0.19-0.62) was the most strongly associated with incident diabetes. Thus increasing physical activity may substantially reduce the incidence of type 2 diabetes in high-risk individuals...
  65. ncbi request reprint The infant growth of boys who later develop coronary heart disease
    Tom J Forsen
    National Public Health Institute, Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, Helsinki, Finland
    Ann Med 36:389-92. 2004
    ..The association between low birth-weight and coronary heart disease has been repeatedly shown. Only two previous studies have examined the effects of weight gain during infancy and later coronary heart disease...
  66. ncbi request reprint Prevalence of the metabolic syndrome and its components: findings from a Finnish general population sample and the Diabetes Prevention Study cohort
    Pirjo Ilanne-Parikka
    The Diabetes Center, Kirjoniementie 15, FIN 33680 Tampere, Finland
    Diabetes Care 27:2135-40. 2004
    ..To assess the prevalence of the metabolic syndrome (MetS) in two independent Finnish study cohorts...
  67. ncbi request reprint Interactions between peroxisome proliferator-activated receptor-gamma 2 gene polymorphisms and size at birth on blood pressure and the use of antihypertensive medication
    Hilkka Ylihärsilä
    National Public Health Institute, Helsinki, University of Helsinki, Finland
    J Hypertens 22:1283-7. 2004
    ..We examined whether the association between small body size at birth and adult blood pressure is modulated by PPAR-gamma 2 gene polymorphism, and whether the use of any class of antihypertensive medication is related to birth size...
  68. ncbi request reprint The association of the K121Q polymorphism of the plasma cell glycoprotein-1 gene with type 2 diabetes and hypertension depends on size at birth
    Agata Kubaszek
    Department of Medicine, University of Kuopio, 70210 Kuopio, Finland
    J Clin Endocrinol Metab 89:2044-7. 2004
    ..We conclude that the interaction between the K121Q polymorphism of the PC-1 gene and birth length affects insulin sensitivity and increases susceptibility to type 2 diabetes and hypertension in adulthood...
  69. ncbi request reprint Physical activity, body mass index, and risk of type 2 diabetes in patients with normal or impaired glucose regulation
    Gang Hu
    Department of Epidemiology and Health Promotion, National Public Health Institute, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    Arch Intern Med 164:892-6. 2004
    ..Sedentary lifestyle, obesity, and impaired glucose regulation are associated with the risk of type 2 diabetes. However, the joint associations of these risk factors are not known...
  70. ncbi request reprint Pathways of infant and childhood growth that lead to type 2 diabetes
    Johan G Eriksson
    National Public Health Institute, Department of Epidemiology and Health Promotion, Diabetes and Genetic Epidemiology Unit, Helsinki, Finland
    Diabetes Care 26:3006-10. 2003
    ..The aim of this study was to explore the pathways of infant and early growth that lead to type 2 diabetes in adult life...
  71. ncbi request reprint Interactions between peroxisome proliferator-activated receptor gene polymorphism and birth length influence risk for type 2 diabetes
    Johan G Eriksson
    Diabetes Care 26:2476-7. 2003
  72. ncbi request reprint Prevention of diabetes mellitus in subjects with impaired glucose tolerance in the Finnish Diabetes Prevention Study: results from a randomized clinical trial
    Jaana Lindström
    National Public Health Institute, Department of Epidemiology, Diabetes and Genetic Epidemiology Unit, Helsinki, Finland
    J Am Soc Nephrol 14:S108-13. 2003
    ..In conclusion, the DPS is the first controlled trial demonstrating that type 2 diabetes can be prevented by changes in lifestyle in high-risk subjects...
  73. ncbi request reprint Self-perpetuating effects of birth size on blood pressure levels in elderly people
    Hilkka Ylihärsilä
    Hospital for Children and Adolescents, Helsinki University Central Hospital, Helsink, Finland
    Hypertension 41:446-50. 2003
    ..Among elderly people with established hypertension, these processes have a strong effect on blood pressure levels, because they are processes that do not respond well to treatment...
  74. ncbi request reprint Growth and living conditions in childhood and hypertension in adult life: a longitudinal study
    David J P Barker
    MRC Environmental Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK
    J Hypertens 20:1951-6. 2002
    ..To examine the interplay between childhood growth and living conditions in the development of hypertension...
  75. ncbi request reprint Associations of body size at birth with late-life cortisol concentrations and glucose tolerance are modified by haplotypes of the glucocorticoid receptor gene
    Anna Rautanen
    Department of Medical Genetics, University of Helsinki, FIN 00014 Helsinki, Finland
    J Clin Endocrinol Metab 91:4544-51. 2006
    ..Small body size at birth is associated with cardiovascular disease and type 2 diabetes in adult life. This link may be in part mediated by early-life programming of the hypothalamic-pituitary-adrenal axis (HPAA) function...
  76. ncbi request reprint Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study
    Virpi I Lindi
    Department of Clinical Nutrition, University of Kuopio and Kuopio University Hospital, Kuopio, Finland
    Diabetes 51:2581-6. 2002
    ..However, beneficial changes in diet, increases in physical activity, and weight loss may reverse, to some extent, the diabetogenic impact of the Ala12 allele, possibly due to an improved insulin sensitivity...
  77. ncbi request reprint Length of gestation and depressive symptoms at age 60 years
    Katri Raikkonen
    Department of Psychology, University of Helsinki, PO Box 9, 00014 University of Helsinki, Finland
    Br J Psychiatry 190:469-74. 2007
    ..A non-optimal foetal environment, reflected in smaller birth size and shorter duration of gestation, is a risk factor for compromised health later in life...
  78. ncbi request reprint Glucose regulation in young adults with very low birth weight
    Petteri Hovi
    Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
    N Engl J Med 356:2053-63. 2007
    ..We assessed glucose tolerance and insulin sensitivity and measured serum lipid levels and blood pressure in young adults with very low birth weight...
  79. ncbi request reprint Childhood growth and hypertension in later life
    Johan G Eriksson
    National Public Health Institute, Department of Health Promotion and Chronic Disease Prevention, Diabetes Unit, Helsinki, Finland
    Hypertension 49:1415-21. 2007
    ..28 to 1.57). We conclude that 2 different paths of childhood growth precede the development of hypertension. We suggest that they lead to hypertension through different biological mechanisms and may respond differently to medication...
  80. ncbi request reprint Gene polymorphisms, size at birth, and the development of hypertension and type 2 diabetes
    Johan G Eriksson
    University of Helsinki, Department of Public Health, 00014 University of Helsinki, Finland
    J Nutr 137:1063-5. 2007
    ..These findings reflect gene-early environment interactions and can be attributed to the phenomenon of developmental plasticity...
  81. ncbi request reprint Physical activity, diet, and incident diabetes in relation to an ADRA2B polymorphism
    David E Laaksonen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Med Sci Sports Exerc 39:227-32. 2007
    ..We assessed the associations of leisure-time physical activity (LTPA), dietary changes, and weight loss on the risk of type 2 diabetes according to the 12Glu9 polymorphism in 481 participants of the Finnish Diabetes Prevention Study...
  82. ncbi request reprint Infant growth and stroke in adult life: the Helsinki birth cohort study
    Clive Osmond
    MRC Epidemiology Resource Centre, University of Southampton, Southampton SO16 6YD, UK
    Stroke 38:264-70. 2007
    ..People who had low birth weight are at increased risk of stroke. Little is known about the effects of early postnatal growth on stroke risk...
  83. ncbi request reprint Serum uric acid as a harbinger of metabolic outcome in subjects with impaired glucose tolerance: the Finnish Diabetes Prevention Study
    Leo Niskanen
    Department of Medicine, Kuopio University Hospital, Bld nro 5, FIN 70210, Kuopio, Finland
    Diabetes Care 29:709-11. 2006
  84. ncbi request reprint Sustained reduction in the incidence of type 2 diabetes by lifestyle intervention: follow-up of the Finnish Diabetes Prevention Study
    Jaana Lindström
    Diabetes Unit, Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland
    Lancet 368:1673-9. 2006
    ..In the extended follow-up of the Finnish Diabetes Prevention Study, we assessed the extent to which the originally-achieved lifestyle changes and risk reduction remain after discontinuation of active counselling...
  85. ncbi request reprint Association between ghrelin gene variations and blood pressure in subjects with impaired glucose tolerance
    Ursula Mager
    Department of Public Health and Clinical Nutrition and Food and Health Research Centre, University of Kuopio, Kuopio, Finland
    Am J Hypertens 19:920-6. 2006
    ..In the present study we genotyped six variants of the ghrelin gene and its promoter, and tested whether these single nucleotide polymorphisms (SNPs) were associated with BP levels in participants of the Finnish Diabetes Prevention Study...
  86. ncbi request reprint Spontaneous hypothyroidism in adult women is predicted by small body size at birth and during childhood
    Eero Kajantie
    National Public Health Institute, Department of Epidemiology and Health Promotion, Mannerheimintie 166, 00300 Helsinki, Finland
    J Clin Endocrinol Metab 91:4953-6. 2006
    ..The relationships of early growth with coronary heart disease and type 2 diabetes have received considerable attention. It is not known whether fetal or childhood growth is linked with autoimmune disorders...
  87. ncbi request reprint Depressive symptoms in adults separated from their parents as children: a natural experiment during World War II
    Anu Katriina Pesonen
    Department of Psychology, University of Helsinki, Helsinki, Finland
    Am J Epidemiol 166:1126-33. 2007
    ..Those separated from their father because of the father's military assignment (n = 744) did not differ from those who were not separated...
  88. ncbi request reprint Very low birth weight increases risk for sleep-disordered breathing in young adulthood: the Helsinki Study of Very Low Birth Weight Adults
    E Juulia Paavonen
    Department of Psychology, PO Box 9, 00014 University of Helsinki, Helsinki, Finland
    Pediatrics 120:778-84. 2007
    ..We investigated whether very low birth weight (<1500 g) is associated with the risk of sleep-disordered breathing in young adulthood...
  89. ncbi request reprint Birth weight and systolic blood pressure in adolescence and adulthood: meta-regression analysis of sex- and age-specific results from 20 Nordic studies
    Michael Gamborg
    Institute of Preventive Medicine, Copenhagen University Hospital, Copenhagen, Denmark
    Am J Epidemiol 166:634-45. 2007
    ..This meta-analysis supports the evidence of an inverse birth weight-SBP association, regardless of adjustment for concurrent body size. It also reveals important heterogeneity in the shape and strength of the association by sex and age...
  90. pmc The fetal origins hypothesis--10 years on
    Johan G Eriksson
    BMJ 330:1096-7. 2005
  91. ncbi request reprint Methodologic considerations in the measurement of glycemic index: glycemic response to rye bread, oatmeal porridge, and mashed potato
    Katja A Hätönen
    Department of Health Promotion and Chronic Disease Prevention and of Health and Functional Capacity, The National Public Health Institute, Helsinki, Finland
    Am J Clin Nutr 84:1055-61. 2006
    ..Methodologic choices affect measures of the glycemic index (GI). The effects on GI values of blood sampling site, reference food type, and the number of repeat tests have been insufficiently determined...
  92. doi request reprint Depression in young adults with very low birth weight: the Helsinki study of very low-birth-weight adults
    Katri Raikkonen
    Department of Psychology, University of Helsinki, PO Box 9, FI 00014 Helsinki, Finland
    Arch Gen Psychiatry 65:290-6. 2008
    ..Little is known about the mental health outcomes of very low-birth-weight (VLBW) (< 1500 g) infants in young adulthood...