Research Topics
| C J ErikssonSummaryAffiliation: National Public Health Institute Country: Finland Publications
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Detail Information
Publications
The role of acetaldehyde in the actions of alcohol (update 2000)C J Eriksson
Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
Alcohol Clin Exp Res 25:15S-32S. 2001..Recent advances in the field of acetaldehyde (AcH) research have raised the need for a comprehensive review on the role of AcH in the actions of alcohol. This update is an attempt to summarize the available AcH research...- Acceleration of ethanol and acetaldehyde oxidation by D-glycerate in ratsC J Peter Eriksson
Department of Mental Health and Alcohol Research, National Public Health Institute, PO Box 33, 00251 Helsinki, Finland
Metabolism 56:895-8. 2007..Further studies are needed to investigate how the AcH could be even more efficiently oxidized to reduce the harmful effects of ethanol-derived AcH... - Oestradiol and human male alcohol-related aggressionC J Peter Eriksson
Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
Alcohol Alcohol 38:589-96. 2003..This new aspect was studied in the present investigation involving men with a history of alcohol-related aggression (AGG+) and in an age-matched male control population (AGG-)... - Functional relevance of human adh polymorphismC J Eriksson
Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki Finland
Alcohol Clin Exp Res 25:157S-163S. 2001..Viljoen, L. Brooke, T. Stewart, T. Foroud, J. Su, and Ting-Kai Li; and (6) ADH genotypes and alcohol use in Europeans, by John B. Whitfield... - Alcohol intake, androgen and glucocorticoid steroids in premenopausal women using oral contraceptives: an interventional studyT Sarkola
Department of Mental Health and Alcohol Research, National Public Health Institute, POB 719, FIN 00101, Helsinki, Finland
J Steroid Biochem Mol Biol 78:157-65. 2001..The present results may be of relevance in the development of disturbances in the glucocorticoid as well as sex steroid balance among heavy female drinkers... - Lack of effect of alcohol on ethinylestradiol in premenopausal womenT Sarkola
Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
Contraception 63:19-23. 2001..The lack of an acute effect comparable to that reported for estradiol may be due to the protection of the ethinyl group at the 17-position of ethinylestradiol... - Effect of 4-methylpyrazole on endogenous plasma ethanol and methanol levels in humansT Sarkola
Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
Alcohol Clin Exp Res 25:513-6. 2001..The objective of the present study was to investigate the effect of 4-methylpyrazole (4-MP), a specific ADH inhibitor, on endogenous plasma methanol and ethanol levels in healthy women and men... - [Alcohol and aggressive behavior]Bettina von der Pahlen
Kansanterveyslaitos, mielenterveyden ja alkoholitutkimuksen osasto PL 33, 00251 Helsinki
Duodecim 119:2488-93. 2003 - Measurement of acetaldehyde: what levels occur naturally and in response to alcohol?C J Peter Eriksson
National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland
Novartis Found Symp 285:247-55; discussion 256-60. 2007..The problem with rapid acetaldehyde oxidation, which may markedly affect the recovery of low acetaldehyde levels, also needs to be solved... - [Alcohol and female steroid hormones]Taisto Sarkola
Kansanterveyslaitos, mielenterveyden ja alkoholitutkimuksen osasto, , 00251 Helsinki
Duodecim 118:1325-30. 2002 - The role of the liver in the acute effect of alcohol on androgens in womenT Sarkola
Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
J Clin Endocrinol Metab 86:1981-5. 2001..Our results suggests that the liver should be included as a major site in the acute endocrinological effects of alcohol on steroid hormones in women... - The role of social isolation in the effects of alcohol on corticosterone and testosterone levels of alcohol-preferring and non-preferring ratsSusanna J Apter
Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
Alcohol Alcohol 41:33-8. 2006..CONCLUSIONS: We suggest that social isolation, representing stress, may constitute a situation in which the HPA and HPG axes are connected together in promoting alcohol drinking... - Testosterone, 5 alpha-dihydrotestosterone and cortisol in men with and without alcohol-related aggressionPahlen Bettina von der
Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
J Stud Alcohol 63:518-26. 2002..These mechanisms, as well as age, androgens and cortisol, all represent factors that, in combination, regulate human aggression... - The effect of alcohol on testosterone concentrations in alcohol-preferring and non-preferring rat linesSusanna J Apter
Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
Alcohol Clin Exp Res 27:1190-3. 2003.... - Testosterone and alcohol use among adolescent male twins: testing between-family associations in within-family comparisonsC J Peter Eriksson
Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
Behav Genet 35:359-68. 2005..The phenotypic correlation between T and pubertal maturation is largely genetic, inviting study of the magnitude and meaning of linkages between testosterone and symptoms of alcoholism on follow-up in early adulthood... - Urinary ethyl glucuronide and 5-hydroxytryptophol levels during repeated ethanol ingestion in healthy human subjectsTaisto Sarkola
Department of Mental Health and Alcohol Research, National Public Health Institute, POB 33, Fin 00251 Helsinki, Finland
Alcohol Alcohol 38:347-51. 2003.... - Testosterone increases in men after a low dose of alcoholTaisto Sarkola
Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
Alcohol Clin Exp Res 27:682-5. 2003..CONCLUSIONS: Alcohol intake affects the androgen balance in men through an effect mediated by the alcohol-induced change in the redox state in the liver... - Ethanol, acetaldehyde, acetate, and lactate levels after alcohol intake in white men and women: effect of 4-methylpyrazoleTaisto Sarkola
Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
Alcohol Clin Exp Res 26:239-45. 2002.... - Effect of moderate alcohol consumption on plasma dehydroepiandrosterone sulfate, testosterone, and estradiol levels in middle-aged men and postmenopausal women: a diet-controlled intervention studyAafje Sierksma
Department of Nutritional Physiology, TNO Nutrition and Food Research, Zeist, The Netherlands
Alcohol Clin Exp Res 28:780-5. 2004..44, p = 0.08; r = 0.32, p = 0.21; and r = 0.46, p = 0.06, respectively). CONCLUSIONS: A protective effect of moderate alcohol consumption for cardiovascular disease risk may in part be explained by increased plasma DHEAS level... - Combined calcium carbimide and ethanol treatment induces high blood acetaldehyde levels, myocardial apoptosis and altered expression of apoptosis-regulating genes in ratHeidi Jänkälä
Department of Clinical Chemistry, Helsinki University Central Hospital, Haartmaninkatu 4, SF 00290, Finland
Alcohol Alcohol 37:222-8. 2002..These results indicate that acetaldehyde might regulate the expression of apoptosis-linked genes and that apoptosis of myocardial cells may be involved in the development of alcoholic heart disease... - Early deprivation increases exploration and locomotion in adult male Wistar offspringMaarit Marmendal
Department of Psychology, Goteborg University, P O Box 500, SE 405 30 Goteborg, Sweden
Pharmacol Biochem Behav 85:535-44. 2006..Furthermore, the present study demonstrates that methodological issues within the maternal separation paradigm may be influential factors for behavioral changes in adulthood... - Increased plasma fatty acid ethyl ester levels following inhibition of oxidative metabolism of ethanol by 4-methylpyrazole treatment in human subjectsCatherine A Best
Department of Pathology, Division of Laboratory Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
Alcohol Clin Exp Res 30:1126-31. 2006..CONCLUSIONS: Our results indicate that the in vivo inhibition of the oxidative metabolism of ethanol using 4-MP results in an increased circulating concentration of FAEE, products of the nonoxidative metabolism of ethanol... - Testosterone, sexuality and antisocial personality in rapists and child molesters: a pilot studyAnu S Aromäki
Department of Psychology, Abo Akademi University, FIN 20500 Turku, Finland
Psychiatry Res 110:239-47. 2002..The implications of these results are discussed... - Is ethanol a pro-drug? Acetaldehyde contribution to brain ethanol effectsEtienne Quertemont
Neuroscience Comportementale et Psychopharmacologie, University of Liege, Belgium
Alcohol Clin Exp Res 29:1514-21. 2005..Rodd and Richard R. Bell; (4) Molecular and biochemical changes associated with acetaldehyde in human alcoholism and alcohol abuse, by C. J. Peter Eriksson... - Laboratory tests for acute alcohol consumption: results of the WHO/ISBRA Study on State and Trait Markers of Alcohol Use and DependenceAnders Helander
Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
Alcohol Clin Exp Res 26:1070-7. 2002..Comparison was made with self-reported drinking levels... 
Nuclear factor-eythroid 2-related factor 2 prevents alcohol-induced fulminant liver injuryJutta Lamlé
Department of Hepatology, Gastroenterology and Endocrinology, Hannover, Germany
Gastroenterology 134:1159-68. 2008..Increased oxidative stress has been implicated in the pathophysiology of many diseases including ethanol-induced liver disease. Therefore, the role of Nrf2(-/-) in ethanol-induced liver injury was investigated...