Research Topics
Species | A AroSummaryAffiliation: National Public Health Institute Country: Finland Publications
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Detail Information
Publications
[Homocysteine and coronary artery disease]Antti Aro
Kansanterveyslaitos, terveyden ja toimintakyvyn osasto Mannerheimintie 166 00300 Helsinki
Duodecim 119:1131-5. 2003
Antioxidant supplementation and risk of chronic diseaseAntti Aro
National Public Health Institute, Helsinki, Finland
Forum Nutr 56:361-3. 2003
[Vitamin D--multifunctional hormone]Antti Aro
Kansanterveyslaitos, Helsinki
Duodecim 121:1749-54. 2005
Inverse association between dietary and serum conjugated linoleic acid and risk of breast cancer in postmenopausal womenA Aro
Department of Nutrition, National Public Health Institute, Helsinki, Finland
Nutr Cancer 38:151-7. 2000..The findings may be of relevance for food production, inasmuch as it is possible to increase CLA and its precursor trans-vaccenic acid in foods by modifying the feeding of ruminants...
The scientific basis for trans fatty acid regulations-is it sufficient? A European perspectiveAntti Aro
Department of Health and Functional Capacity, National Public Health Institute KTL, Mannerheimintie 166, FI 00300 Helsinki, Finland
Atheroscler Suppl 7:67-8. 2006..When modifying the dietary fat composition the proportion of saturated plus TFA should be kept to one-third of total dietary fatty acid intake...
Effects of reduced-fat diets with different fatty acid compositions on serum lipoprotein lipids and apolipoproteinsA Aro
Department of Nutrition, National Public Health Institute, Helsinki, Finland
Public Health Nutr 1:109-16. 1998..To compare the effects on serum lipoproteins of three isocaloric diets with reduced total fat and saturated fatty acid (SFA) contents but with different proportions of monounsaturated (MUFA) and polyunsaturated fatty acids (PUFA)...
[Diet as medical treatment for diabetes]Antti Aro
Duodecim 120:2108-11. 2004
Stearic acid, trans fatty acids, and dairy fat: effects on serum and lipoprotein lipids, apolipoproteins, lipoprotein(a), and lipid transfer proteins in healthy subjectsA Aro
Department of Nutrition, National Public Health Institute, Helsinki, Finland
Am J Clin Nutr 65:1419-26. 1997..Dietary fats low in both saturated fatty acids and trans fatty acids should be favored...
Plasma kinetics and urinary excretion of the flavanones naringenin and hesperetin in humans after ingestion of orange juice and grapefruit juiceI Erlund
Department of Nutrition, National Public Health Institute KTL, Mannerheimintie 166 F, FIN 00300 Helsinki, Finland
J Nutr 131:235-41. 2001..We conclude that because of the relatively high concentrations of flavanones in plasma after ingestion of orange juice or grapefruit juice, considerable health effects could ensue in individuals consuming them regularly...
Folate intake, plasma folate and homocysteine status in a random Finnish populationG Alfthan
Department of Health and Functional Capacity, National Public Health Institute, Mannerheimintie, Helsinki, Finland
Eur J Clin Nutr 57:81-8. 2003..To assess the folate status of Finnish adults using plasma folate and homocysteine as biomarkers and to evaluate dietary and supplementary folate intakes...
Effect of alpha-tocopherol (vitamin E) and beta-carotene supplementation on the incidence of intermittent claudication in male smokersM Tornwall
Department of Nutrition, National Public Health Institute, Helsinki, Finland
Arterioscler Thromb Vasc Biol 17:3475-80. 1997..96 (0.89-1.04). In conclusion, no primary preventive effect on intermittent claudication was observed among middle-aged male smokers who were supplemented with alpha-tocopherol, beta-carotene, or both...
Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteersI Erlund
Department of Nutrition, National Public Health Institute KTL, Mannerheimintie 166, FIN 00300 Helsinki, Finland
Eur J Clin Pharmacol 56:545-53. 2000..It mainly occurs in plants as glycosides, such as rutin (quercetin rutinoside) in tea. Quercetin and rutin are used in many countries as vasoprotectants and are ingredients of numerous multivitamin preparations and herbal remedies...
Selenium metabolism and platelet glutathione peroxidase activity in healthy Finnish men: effects of selenium yeast, selenite, and selenateG Alfthan
Department of Biochemistry, National Public Health Institute, Kansanterveyslaitos, Helsinki, Finland
Am J Clin Nutr 53:120-5. 1991..25-1.45 mumol/L. At the present selenium intake in Finland, 100 micrograms/d, GSHPx activity is saturated in plasma and red cells and almost saturated in platelets...
Dyslipidemia and an unfavorable fatty acid profile predict left ventricular hypertrophy 20 years laterJ Sundstrom
Departments of Public Health and Caring Sciences J S, B V, H O L and Medical Sciences L L, B A, Uppsala University, Sweden, and Department of Nutrition A A, KTL National Public Health Institute, Helsinki, Finland
Circulation 103:836-41. 2001....
Validated method for the quantitation of quercetin from human plasma using high-performance liquid chromatography with electrochemical detectionI Erlund
Department of Nutrition, National Public Health Institute, Helsinki, Finland
J Chromatogr B Biomed Sci Appl 727:179-89. 1999..No free quercetin was detected in plasma and no evidence of significant amounts of quercetin glycosides in plasma was found...
Efficacy and safety of food fortification with calcium among adults in FinlandTero Hirvonen
National Public Health Institute, Department of Epidemiology and Health Promotion, Mannerheimintie 166, FIN 00300 Helsinki, Finland
Public Health Nutr 9:792-7. 2006..To examine the efficacy and safety of foods fortified with calcium in the adult population in Finland...
The effect of low doses of betaine on plasma homocysteine in healthy volunteersGeorg Alfthan
Department of Health and Functional Capacity, National Public Health Institute KTL, Helsinki, Finland
Br J Nutr 92:665-9. 2004..Plasma betaine increased from 31 (sd 13) to 255 (sd 136) mumol/l in a dose-dependent manner (R(2) 0.97). We conclude that plasma tHcy is lowered rapidly and significantly by 3 or 6 g betaine/d in healthy men and women...
The effect of alpha-tocopherol and beta-carotene supplementation on symptoms and progression of intermittent claudication in a controlled trialM E Törnwall
ATBC Study, Department of Nutrition, National Public Health Institute, Mannerheimintie 166, 00300, Helsinki, Finland
Atherosclerosis 147:193-7. 1999..Alpha-tocopherol supplementation had no effect. In conclusion, long-term supplementation with alpha-tocopherol and beta-carotene showed no beneficial effect on symptoms and progression of intermittent claudication...
The Pro12Ala polymorphism of the PPAR-gamma2 gene affects associations of fish intake and marine n-3 fatty acids with glucose metabolismS K Ylönen
Department of Applied Chemistry and Microbiology, Division of Nutrition, University of Helsinki, Helsinki, Finland
Eur J Clin Nutr 62:1432-9. 2008..The design comprises of the cross-sectional analysis...
Consumption of black currants, lingonberries and bilberries increases serum quercetin concentrationsI Erlund
Biomarker Laboratory, National Public Health Institute, Helsinki, Finland
Eur J Clin Nutr 57:37-42. 2003..To study serum quercetin concentrations of subjects consuming berries or habitual Finnish diets...
The effect of flaxseed supplementation in processed foods on serum fatty acids and enterolactoneS Tarpila
Department of Internal Medicine, The Mehiläinen Hospital, Helsinki, Finland
Eur J Clin Nutr 56:157-65. 2002..The purpose was to study the effects of flaxseed supplementation as a part of daily diet on serum lipids, fatty acids and plasma enterolactone...
Plasma concentrations of the flavonoids hesperetin, naringenin and quercetin in human subjects following their habitual diets, and diets high or low in fruit and vegetablesI Erlund
Biomarker Laboratory, National Public Health Institute KTL, Helsinki, Finland
Eur J Clin Nutr 56:891-8. 2002..To investigate whether plasma concentrations of flavanones can serve as biomarkers of their intake...
Iron status of adults in the capital area of FinlandMarjaana Lahti-Koski
Dept. of Epidemiology and Health Promotion, National Public Health Institute (KTL, Mannerheimintie 166, 00300, Helsinki, Finland
Eur J Nutr 42:287-92. 2003..CONCLUSIONS: While iron status is fairly good among Finnish males, especially in younger women it is suboptimal,with iron intake failing to reach recommended levels. Food consumption was poorly associated with iron status...
Vitamin D status and the risk of cardiovascular disease deathAnnamari Kilkkinen
National Institute for Health and Welfare, Helsinki, Finland
Am J Epidemiol 170:1032-9. 2009..These findings need to be replicated in other populations. To demonstrate a causal link between vitamin D and CVD, randomized controlled trials are required...
Associations of dietary fiber with glucose metabolism in nondiabetic relatives of subjects with type 2 diabetes: the Botnia Dietary StudyKatriina Ylönen
Department of Applied Chemistry and Microbiology, Division of Nutrition, University of Helsinki, Helsinki, Finland
Diabetes Care 26:1979-85. 2003..To study cross-sectional associations of dietary fiber intake with insulin resistance, insulin secretion, and glucose tolerance in a population at high risk for type 2 diabetes...
Tomato juice decreases LDL cholesterol levels and increases LDL resistance to oxidationMarja Leena Silaste
Department of Internal Medicine, University of Oulu, P O Box 5000, 90014 Oulu, Finland
Br J Nutr 98:1251-8. 2007..These atheroprotective features associated with changes in serum lycopene, beta-carotene and gamma-carotene levels...
Plasma homocysteine concentration is decreased by dietary interventionMarja Leena Silaste
Department of Internal Medicine, University of Oulu, Oulu, Finland
Br J Nutr 89:295-301. 2003..001). In conclusion, a diet high in fresh berries, citrus fruit, and vegetables effectively increases serum and RBC folate and decreases plasma homocysteine...
Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjectsUrsula Schwab
Department of Clinical Nutrition, University of Kuopio, Kuopio, Finland
Am J Clin Nutr 76:961-7. 2002..It is involved in homocysteine metabolism as an alternative methyl donor and is used in the treatment of homocystinuria in humans. In pigs, betaine decreases the amount of adipose tissue...
Risk analysis applied to food fortificationHelle M Meltzer
Norwegian Institute of Public Health, Oslo, Division of Environmental Medicine, PO Box 4404 Nydalen, N 0403 Oslo, Norway
Public Health Nutr 6:281-91. 2003..To describe how a risk analysis can be applied to food fortification, with emphasis on voluntary fortification and intake levels that might exceed usual dietary levels...
PASSCLAIM - Diet-related cardiovascular diseaseRonald P Mensink
Maastricht University, Department of Human Biology, P. O. Box 616, 6200 MD Maastricht, The Netherlands
Eur J Nutr 42:I6-27. 2003..Therefore, studies to further validate generic predictors for the CVD risk should be initiated...
Bioconversion of vaccenic acid to conjugated linoleic acid in humansAnu M Turpeinen
Department of Applied Chemistry, University of Helsinki, Finland
Am J Clin Nutr 76:504-10. 2002..Conversion is likely to contribute significantly to the amount of RA available to the body, and dietary intakes of VA should thus be taken into account when predicting RA status...
Dietary intakes and plasma concentrations of carotenoids and tocopherols in relation to glucose metabolism in subjects at high risk of type 2 diabetes: the Botnia Dietary StudyKatriina Ylönen
Department of Applied Chemistry and Microbiology, Division of Nutrition, University of Helsinki, Finland
Am J Clin Nutr 77:1434-41. 2003..The role of antioxidants in the pathogenesis of type 2 diabetes is uncertain...
Effect of alpha-linolenic acid-rich Camelina sativa oil on serum fatty acid composition and serum lipids in hypercholesterolemic subjectsHenna M Karvonen
Oy Foodfiles Ltd (Contract Research Organization, Kupio, Finland
Metabolism 51:1253-60. 2002..Camelina oil's serum cholesterol-lowering effect was comparable to that of rapeseed and olive oils...
High intakes of vegetables, berries, and apples combined with a high intake of linoleic or oleic acid only slightly affect markers of lipid peroxidation and lipoprotein metabolism in healthy subjectsRiitta Freese
University of Helsinki, Department of Applied Chemistry and Microbiology, Division of Nutrition, Finland
Am J Clin Nutr 76:950-60. 2002..The pathophysiology of these diseases involves free radical mechanisms. Diet may either enhance or diminish oxidative stress in the body...
Serum alpha-tocopherol concentrations and risk of type 1 diabetes mellitus: a cohort study in siblings of affected childrenLiisa Uusitalo
Tampere School of Public Health, University of Tampere, Finland
J Pediatr Endocrinol Metab 18:1409-16. 2005..08 and 0.09, respectively). Although the results did not reach statistical significance, they support the hypothesis that high alpha-tocopherol levels may protect against DM1...
[Nordic nutrition recommendations]Wulf Becker
Ugeskr Laeger 168:76-7; author reply 77. 2006
Changes in dietary fat intake alter plasma levels of oxidized low-density lipoprotein and lipoprotein(a)Marja Leena Silaste
Department of Internal Medicine and Biocenter Oulu, University of Oulu, Finland
Arterioscler Thromb Vasc Biol 24:498-503. 2004..To assess the effects of dietary modifications on oxidized low-density lipoprotein (LDL)...
Orally administered betaine has an acute and dose-dependent effect on serum betaine and plasma homocysteine concentrations in healthy humansUrsula Schwab
Department of Clinical Nutrition, University of Kuopio, Finland
J Nutr 136:34-8. 2006..In conclusion, a single dose of orally administered betaine had an acute and dose-dependent effect on serum betaine concentration and resulted in lowered plasma tHcy concentrations within 2 h in healthy subjects...
