Hannu Alho

Summary

Affiliation: National Public Health Institute
Country: Finland

Publications

  1. pmc A retrospective evaluation of patients switched from buprenorphine (Subutex) to the buprenorphine/naloxone combination (Suboxone)
    Kaarlo Simojoki
    Espoo Treatment and Rehabilitation Center, A clinic Foundation, Espoo, Finland
    Subst Abuse Treat Prev Policy 3:16. 2008
  2. ncbi Long-term effects of and physiological responses to nitrous oxide gas treatment during alcohol withdrawal: a double-blind, placebo-controlled trial
    Hannu Alho
    National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland
    Alcohol Clin Exp Res 26:1816-22. 2002
  3. ncbi Abuse liability of buprenorphine-naloxone tablets in untreated IV drug users
    Hannu Alho
    National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland
    Drug Alcohol Depend 88:75-8. 2007
  4. doi Alcohol consumption and all-cause mortality among elderly in Finland
    Jukka T Halme
    National Institute for Health and Welfare, Helsinki, Finland
    Drug Alcohol Depend 106:212-8. 2010
  5. doi Hazardous drinking: prevalence and associations in the Finnish general population
    Jukka T Halme
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Alcohol Clin Exp Res 32:1615-22. 2008
  6. pmc Treatment of alcohol dependence in patients with co-morbid major depressive disorder--predictors for the outcomes with memantine and escitalopram medication
    Leea H Muhonen
    National Public Health Institute, Department of Mental Health and Alcohol Research, Finland
    Subst Abuse Treat Prev Policy 3:20. 2008
  7. ncbi Predictors of dropout in an outpatient treatment for problem drinkers including cognitive-behavioral therapy and the opioid antagonist naltrexone
    Salla Vuoristo-Myllys
    Institute of Behavioural Sciences, University of Helsinki, Finland, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    J Stud Alcohol Drugs 74:894-901. 2013
  8. pmc Memory function in opioid-dependent patients treated with methadone or buprenorphine along with benzodiazepine: longitudinal change in comparison to healthy individuals
    Pekka Rapeli
    Unit for Drug Dependence, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland
    Subst Abuse Treat Prev Policy 4:6. 2009
  9. doi Age at onset of first depressive episode as a predictor for escitalopram treatment of major depression comorbid with alcohol dependence
    Leea H Muhonen
    National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland
    Psychiatry Res 167:115-22. 2009
  10. pmc An analysis of problem gambling among the Finnish working-age population: a population survey
    Sari Castrén
    Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    BMC Public Health 13:519. 2013

Collaborators

Detail Information

Publications31

  1. pmc A retrospective evaluation of patients switched from buprenorphine (Subutex) to the buprenorphine/naloxone combination (Suboxone)
    Kaarlo Simojoki
    Espoo Treatment and Rehabilitation Center, A clinic Foundation, Espoo, Finland
    Subst Abuse Treat Prev Policy 3:16. 2008
    ..In order to curb this problem, many treatment centres transferred ("forced transfer") their buprenorphine patients to the buprenorphine plus naloxone (Suboxone) combination product in late 2003...
  2. ncbi Long-term effects of and physiological responses to nitrous oxide gas treatment during alcohol withdrawal: a double-blind, placebo-controlled trial
    Hannu Alho
    National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland
    Alcohol Clin Exp Res 26:1816-22. 2002
    ..The aim of the present study was to characterize other effects and side effects of the N2O treatment using several objective measures and to study the possible long-term efficacy of the treatment...
  3. ncbi Abuse liability of buprenorphine-naloxone tablets in untreated IV drug users
    Hannu Alho
    National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland
    Drug Alcohol Depend 88:75-8. 2007
    ..Its street price was less than half that of buprenorphine alone. The buprenorphine+naloxone combination appears to be a feasible tool, along with easier access to addiction treatment, for decreasing IV abuse of buprenorphine...
  4. doi Alcohol consumption and all-cause mortality among elderly in Finland
    Jukka T Halme
    National Institute for Health and Welfare, Helsinki, Finland
    Drug Alcohol Depend 106:212-8. 2010
    ..To estimate the gender-specific prevalences of alcohol consumption levels and to investigate the association between heavy drinking and all-cause mortality among elderly males...
  5. doi Hazardous drinking: prevalence and associations in the Finnish general population
    Jukka T Halme
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Alcohol Clin Exp Res 32:1615-22. 2008
    ..This study aimed to investigate the prevalence and associations of hazardous drinking in comparison to AUDs, moderate drinking, and abstinence...
  6. pmc Treatment of alcohol dependence in patients with co-morbid major depressive disorder--predictors for the outcomes with memantine and escitalopram medication
    Leea H Muhonen
    National Public Health Institute, Department of Mental Health and Alcohol Research, Finland
    Subst Abuse Treat Prev Policy 3:20. 2008
    ....
  7. ncbi Predictors of dropout in an outpatient treatment for problem drinkers including cognitive-behavioral therapy and the opioid antagonist naltrexone
    Salla Vuoristo-Myllys
    Institute of Behavioural Sciences, University of Helsinki, Finland, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    J Stud Alcohol Drugs 74:894-901. 2013
    ..We also investigated whether the effectiveness of the treatment (the change in alcohol consumption and symptoms of alcohol craving) or adherence to naltrexone was related to dropout...
  8. pmc Memory function in opioid-dependent patients treated with methadone or buprenorphine along with benzodiazepine: longitudinal change in comparison to healthy individuals
    Pekka Rapeli
    Unit for Drug Dependence, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland
    Subst Abuse Treat Prev Policy 4:6. 2009
    ..The present study is the first to examine longitudinal stability of memory function in OST patients with BZD use, thus providing a new tool for health policy authorities in evaluating the usefulness of OST...
  9. doi Age at onset of first depressive episode as a predictor for escitalopram treatment of major depression comorbid with alcohol dependence
    Leea H Muhonen
    National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland
    Psychiatry Res 167:115-22. 2009
    ..Our study provides evidence that the onset of the first major depressive episode might be a clinically relevant predictor of a response to escitalopram treatment in patients with major depression and comorbid alcohol dependence...
  10. pmc An analysis of problem gambling among the Finnish working-age population: a population survey
    Sari Castrén
    Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    BMC Public Health 13:519. 2013
    ..g. alcohol and nicotine) and the type of games gambled. In this article the prevalence of problem gambling in Finland and the socio-demographic profiles of problem gamblers are studied...
  11. pmc Do drug treatment variables predict cognitive performance in multidrug-treated opioid-dependent patients? A regression analysis study
    Pekka Rapeli
    Unit for Drug Dependence, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland
    Subst Abuse Treat Prev Policy 7:45. 2012
    ..Therefore, we examined whether the cognitive performance of patients in opioid-substitution treatment (OST) is associated with their drug treatment variables...
  12. doi Serotonin transporter polymorphism as a predictor for escitalopram treatment of major depressive disorder comorbid with alcohol dependence
    Leea H Muhonen
    National Institute for Health and Welfare, Department of Mental Health and Substance Abuse Services, Helsinki, Finland
    Psychiatry Res 186:53-7. 2011
    ..This is the first study in the treatment of depression in dual diagnosis patients to report a significant association between outcomes with escitalopram and the 5-HTTLPR gene polymorphism...
  13. ncbi The Alcohol Use Disorders Identification Test (AUDIT) and its derivatives in screening for heavy drinking among the elderly
    Mauri Aalto
    Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    Int J Geriatr Psychiatry 26:881-5. 2011
    ..The aim of the present study was to determine whether tailoring the cut point improves the performance of the AUDIT and its derivatives in this age group...
  14. ncbi Treatment of pathological gambling with naltrexone pharmacotherapy and brief intervention: a pilot study
    Tuuli Lahti
    National Institute for Health and Welfare, Department of Mental Health and Substance Abuse Services, Helsinki, Finland
    Psychopharmacol Bull 43:35-44. 2010
    ..These positive changes suggest that this simple, inexpensive treatment helps pathological gamblers. The role of naltrexone in the treatment effect, however, needs to be determined with a larger, placebo-controlled study...
  15. doi AUDIT and its abbreviated versions in detecting heavy and binge drinking in a general population survey
    Mauri Aalto
    National Institute for Health and Welfare, Helsinki, Finland
    Drug Alcohol Depend 103:25-9. 2009
    ....
  16. pmc Analysis of naltrexone and its metabolite 6-beta-naltrexol in serum with high-performance liquid chromatography
    Pekka Heinälä
    National Public Health Institute, Helsinki, Finland
    BMC Res Notes 5:439. 2012
    ..In this article we introduce a reliable and simple method developed for the simultaneous determination of naltrexone and 6-β-naltrexol in human serum by using high-performance liquid chromatography (HPLC)...
  17. pmc Methadone vs. buprenorphine/naloxone during early opioid substitution treatment: a naturalistic comparison of cognitive performance relative to healthy controls
    Pekka Rapeli
    Unit for Drug Dependence, Department of Psychiatry, Helsinki University Central Hospital, Helsinki, Finland
    BMC Clin Pharmacol 7:5. 2007
    ..Therefore, we investigated attention, working memory, and verbal memory of opioid-dependent patients within six weeks after the introduction of OST in a naturalistic setting and compared to those of healthy controls...
  18. pmc Magnesium treatment in alcoholics: a randomized clinical trial
    Kari Poikolainen
    Finnish Foundation for Alcohol Studies, Helsinki, Finland
    Subst Abuse Treat Prev Policy 3:1. 2008
    ..Magnesium (Mg) deficiency is common among alcoholics. Earlier research suggests that Mg treatment may help to normalize elevated enzyme activities and some other clinically relevant parameters among alcoholics but the evidence is weak...
  19. pmc The impacts of nitrous oxide gas on sleep quality during alcohol withdrawal
    Tuuli Lahti
    Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, Finland
    BMC Res Notes 4:108. 2011
    ..abstract:..
  20. ncbi Opposite associations of carbohydrate-deficient transferrin and gamma-glutamyltransferase with prevalent coronary heart disease
    Pekka Jousilahti
    University of Helsinki, Department of Public Health, PO Box 41, FIN 00014 University of Helsinki, Finland
    Arch Intern Med 162:817-21. 2002
    ..We analyzed the association of 2 commonly used markers of alcohol consumption-carbohydrate-deficient transferrin (CDT) and gamma-glutamyltransferase (GGT)-and self-reported alcohol consumption with prevalent CHD...
  21. ncbi Self-reported alcohol consumption and association to carbohydrate-deficient transferrin and gamma-glutamyltransferase in a random sample of the general population in the Republic of Karelia, Russia and in North Karelia, Finland
    Tiina Laatikainen
    Department of Epidemiology, National Public Health Institute, Mannerheimintie 166, 00300 Helsinki, Finland
    Alcohol Alcohol 37:282-8. 2002
    ..These results suggest that alcohol consumption especially in Russia may not be reliably estimated by self-reporting, and that alcohol consumption is relatively high, especially among men, in RUS...
  22. ncbi Dexmedetomidine in addition to benzodiazepine-based sedation in patients with alcohol withdrawal delirium
    Jukka Tolonen
    aDepartment of Medicine, Division of Emergency Medicine, Helsinki and Uusimaa District University Hospital, Helsinki bDepartment of Emergency Medicine, Middle Finland Central Hospital, Jyväskylä cNational Institute for Health and Welfare, Helsinki, Finland
    Eur J Emerg Med 20:425-7. 2013
    ..3) days. The ICU LOS was 7.1 (2.7) days and in-hospital LOS 12.1 (4.5) days. No adverse events were observed although one patient died from acute pancreatitis. The use of dexmedetomidine in AWD seems safe but warrants further studies. ..
  23. ncbi Double-blind, randomized comparison of memantine and escitalopram for the treatment of major depressive disorder comorbid with alcohol dependence
    Leea H Muhonen
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    J Clin Psychiatry 69:392-9. 2008
    ....
  24. ncbi Alcohol misuse increases serum antibodies to oxidized LDL and C-reactive protein
    Hannu Alho
    Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
    Alcohol Alcohol 39:312-5. 2004
    ..To clarify the relationship of alcohol consumption with serum antibodies to oxidized low-density lipoprotein (oxLDL) and the inflammation marker C-reactive protein (CRP)...
  25. ncbi The association of alcohol dependency with employment probability: evidence from the population survey 'Health 2000 in Finland'
    Edvard Johansson
    Swedish School of Economics and Business Administration, Helsinki, Finland
    Health Econ 16:739-54. 2007
    ..However, accounting for endogeneity increases the negative effect to some 50 percentage points for men and to some 40 percentage points for women...
  26. ncbi Comparison of new alcohol use test, the Helsinki Alcohol Use Test questionnaire, and Alcohol Use Disorders Identification Test and laboratory markers serum gamma-glutamyl transferase and carbohydrate-deficient transferrin
    Annukka Merikallio-Pajunen
    Eira Hospital, Helsinki, Finland
    Addict Behav 29:717-22. 2004
    ..Our results seem to indicate that the HAUT has good performance as screening instrument for alcohol-related problems in the general population...
  27. ncbi Abstaining from alcohol and labour market underperformance--have we forgotten the 'dry' alcoholics?
    Edvard Johansson
    The Research Institute of the Finnish Economy, Lonnrotinkatu 4B, 00120 Helsinki, Finland
    Alcohol Alcohol 41:574-9. 2006
    ..To investigate whether abstainers fare worse than non-abstainers on the labour market because a subset of the abstainers are ex-drinkers with alcohol problems...
  28. ncbi A randomized, multicentre, open-label, comparative trial of disulfiram, naltrexone and acamprosate in the treatment of alcohol dependence
    E Laaksonen
    University of Turku and Turku Health Centre, Finland
    Alcohol Alcohol 43:53-61. 2008
    ..To compare the effects in alcohol-dependent patients of three pharmacotherapies, disulfiram (DIS), naltrexone (NTX), and acamprosate (ACA), when used with a brief manual-based cognitive-behavioural intervention...
  29. ncbi Accuracy of quantity-frequency and graduated frequency questionnaires in measuring alcohol intake: comparison with daily diary and commonly used laboratory markers
    Kari Poikolainen
    Finnish Foundation for Alcohol Studies, P O Box 220, FIN 00531 Helsinki, Finland
    Alcohol Alcohol 37:573-6. 2002
    ....
  30. ncbi Naltrexone for alcohol dependence
    John David Sinclair
    N Engl J Med 346:1329-31; author reply 1329-31. 2002
  31. ncbi [Care of alcohol addiction]
    Mikko Salaspuro
    Duodecim 121:1786-7. 2005