G Alfthan

Summary

Affiliation: National Public Health Institute
Country: Finland

Publications

  1. ncbi request reprint Folate intake, plasma folate and homocysteine status in a random Finnish population
    G Alfthan
    Department of Health and Functional Capacity, National Public Health Institute, Mannerheimintie, Helsinki, Finland
    Eur J Clin Nutr 57:81-8. 2003
  2. doi request reprint The effect of high-fiber rye bread enriched with nonesterified plant sterols on major serum lipids and apolipoproteins in normocholesterolemic individuals
    P P Söderholm
    Folkhalsan Research Center, Biomedicum Helsinki, University of Helsinki, Haartmaninkatu 8, Helsinki, Finland
    Nutr Metab Cardiovasc Dis 22:575-82. 2012
  3. doi request reprint Are serum α- and β-carotene concentrations associated with the development of advanced beta-cell autoimmunity in children with increased genetic susceptibility to type 1 diabetes?
    M Prasad
    Nutrition Unit, Department of Lifestyle and Participation, National Institute for Health and Welfare, Helsinki, Finland
    Diabetes Metab 37:162-7. 2011
  4. ncbi request reprint Homocysteine and major coronary events: a prospective population study amongst women
    P Knekt
    Department of Nutrition and Department of Health and Disability, National Public Health Institute, Helsinki, Finland
    J Intern Med 249:461-5. 2001
  5. ncbi request reprint Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers
    I Erlund
    Department of Nutrition, National Public Health Institute KTL, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    Eur J Clin Pharmacol 56:545-53. 2000
  6. ncbi request reprint Plasma kinetics and urinary excretion of the flavanones naringenin and hesperetin in humans after ingestion of orange juice and grapefruit juice
    I Erlund
    Department of Nutrition, National Public Health Institute KTL, Mannerheimintie 166 F, FIN 00300 Helsinki, Finland
    J Nutr 131:235-41. 2001
  7. ncbi request reprint Hyperhomocystinemia: a risk factor or a consequence of coronary heart disease?
    P Knekt
    National Public Health, Mannerheimintie 166, 00300 Helsinki, Finland
    Arch Intern Med 161:1589-94. 2001
  8. doi request reprint Rye bread intake improves oxidation resistance of LDL in healthy humans
    P P Söderholm
    Folkhalsan Research Center, Biomedicum C315a, PO Box 63, FI 00014 University of Helsinki, Helsinki, Finland
    Atherosclerosis 221:583-6. 2012
  9. ncbi request reprint Consumption of black currants, lingonberries and bilberries increases serum quercetin concentrations
    I Erlund
    Biomarker Laboratory, National Public Health Institute, Helsinki, Finland
    Eur J Clin Nutr 57:37-42. 2003
  10. ncbi request reprint Selenium metabolism and platelet glutathione peroxidase activity in healthy Finnish men: effects of selenium yeast, selenite, and selenate
    G Alfthan
    Department of Biochemistry, National Public Health Institute, Kansanterveyslaitos, Helsinki, Finland
    Am J Clin Nutr 53:120-5. 1991

Detail Information

Publications18

  1. ncbi request reprint Folate intake, plasma folate and homocysteine status in a random Finnish population
    G Alfthan
    Department of Health and Functional Capacity, National Public Health Institute, Mannerheimintie, Helsinki, Finland
    Eur J Clin Nutr 57:81-8. 2003
    ..To assess the folate status of Finnish adults using plasma folate and homocysteine as biomarkers and to evaluate dietary and supplementary folate intakes...
  2. doi request reprint The effect of high-fiber rye bread enriched with nonesterified plant sterols on major serum lipids and apolipoproteins in normocholesterolemic individuals
    P P Söderholm
    Folkhalsan Research Center, Biomedicum Helsinki, University of Helsinki, Haartmaninkatu 8, Helsinki, Finland
    Nutr Metab Cardiovasc Dis 22:575-82. 2012
    ....
  3. doi request reprint Are serum α- and β-carotene concentrations associated with the development of advanced beta-cell autoimmunity in children with increased genetic susceptibility to type 1 diabetes?
    M Prasad
    Nutrition Unit, Department of Lifestyle and Participation, National Institute for Health and Welfare, Helsinki, Finland
    Diabetes Metab 37:162-7. 2011
    ..This study aimed to assess the associations between serum α- and β-carotene concentrations, and the risk of advanced beta-cell autoimmunity, in children with HLA-conferred susceptibility to type 1 diabetes...
  4. ncbi request reprint Homocysteine and major coronary events: a prospective population study amongst women
    P Knekt
    Department of Nutrition and Department of Health and Disability, National Public Health Institute, Helsinki, Finland
    J Intern Med 249:461-5. 2001
    ..To study serum homocysteine concentration for its prediction of major coronary heart disease events amongst women...
  5. ncbi request reprint Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers
    I Erlund
    Department of Nutrition, National Public Health Institute KTL, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    Eur J Clin Pharmacol 56:545-53. 2000
    ..It mainly occurs in plants as glycosides, such as rutin (quercetin rutinoside) in tea. Quercetin and rutin are used in many countries as vasoprotectants and are ingredients of numerous multivitamin preparations and herbal remedies...
  6. ncbi request reprint Plasma kinetics and urinary excretion of the flavanones naringenin and hesperetin in humans after ingestion of orange juice and grapefruit juice
    I Erlund
    Department of Nutrition, National Public Health Institute KTL, Mannerheimintie 166 F, FIN 00300 Helsinki, Finland
    J Nutr 131:235-41. 2001
    ..We conclude that because of the relatively high concentrations of flavanones in plasma after ingestion of orange juice or grapefruit juice, considerable health effects could ensue in individuals consuming them regularly...
  7. ncbi request reprint Hyperhomocystinemia: a risk factor or a consequence of coronary heart disease?
    P Knekt
    National Public Health, Mannerheimintie 166, 00300 Helsinki, Finland
    Arch Intern Med 161:1589-94. 2001
    ..Mild hyperhomocystinemia has been suggested as an indicator of an increased risk of cardiovascular disease...
  8. doi request reprint Rye bread intake improves oxidation resistance of LDL in healthy humans
    P P Söderholm
    Folkhalsan Research Center, Biomedicum C315a, PO Box 63, FI 00014 University of Helsinki, Helsinki, Finland
    Atherosclerosis 221:583-6. 2012
    ..The capacity of LDL to resist oxidation can be determined ex vivo by exposing isolated LDL particles to copper ions and measuring the formation of conjugated dienes by spectrophotometry...
  9. ncbi request reprint Consumption of black currants, lingonberries and bilberries increases serum quercetin concentrations
    I Erlund
    Biomarker Laboratory, National Public Health Institute, Helsinki, Finland
    Eur J Clin Nutr 57:37-42. 2003
    ..To study serum quercetin concentrations of subjects consuming berries or habitual Finnish diets...
  10. ncbi request reprint Selenium metabolism and platelet glutathione peroxidase activity in healthy Finnish men: effects of selenium yeast, selenite, and selenate
    G Alfthan
    Department of Biochemistry, National Public Health Institute, Kansanterveyslaitos, Helsinki, Finland
    Am J Clin Nutr 53:120-5. 1991
    ..25-1.45 mumol/L. At the present selenium intake in Finland, 100 micrograms/d, GSHPx activity is saturated in plasma and red cells and almost saturated in platelets...
  11. ncbi request reprint Cardiovascular risk factor changes in Finland, 1972-1997
    E Vartiainen
    Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
    Int J Epidemiol 29:49-56. 2000
    ..Subsequently, a national cardiovascular risk factors monitoring system was developed to assess the effectiveness of the national strategy...
  12. ncbi request reprint Validated method for the quantitation of quercetin from human plasma using high-performance liquid chromatography with electrochemical detection
    I Erlund
    Department of Nutrition, National Public Health Institute, Helsinki, Finland
    J Chromatogr B Biomed Sci Appl 727:179-89. 1999
    ..No free quercetin was detected in plasma and no evidence of significant amounts of quercetin glycosides in plasma was found...
  13. ncbi request reprint Risk factors for cryptogenic ischaemic stroke
    V Karttunen
    Department of Neurology, Oulu University Central Hospital, Helsinki, Finland
    Eur J Neurol 9:625-32. 2002
    ..Several of the observed risk factors for cryptogenic brain infarction were lifestyle-associated, which emphasizes the role of health education in addition to pharmacological treatment in the prevention of stroke...
  14. ncbi request reprint Relation of inflammation to vascular function in patients with coronary heart disease
    J Sinisalo
    Department of Medicine, Division of Cardiology, The Helsinki University Central Hospital, Meilahti 15krs, Haartmaninkatu 4, FIN 00290, Helsinki, Finland
    Atherosclerosis 149:403-11. 2000
    ..It is possible that endothelial dysfunction in coronary heart disease patients is related to the chronic inflammation or infection coexisting with atherosclerosis...
  15. doi request reprint Serum fatty acids and risk of advanced beta-cell autoimmunity: a nested case-control study among children with HLA-conferred susceptibility to type I diabetes
    S M Virtanen
    Nutrition Unit, National Institute for Health and Welfare, Helsinki, Finland
    Eur J Clin Nutr 64:792-9. 2010
    ....
  16. ncbi request reprint Plasma concentrations of the flavonoids hesperetin, naringenin and quercetin in human subjects following their habitual diets, and diets high or low in fruit and vegetables
    I Erlund
    Biomarker Laboratory, National Public Health Institute KTL, Helsinki, Finland
    Eur J Clin Nutr 56:891-8. 2002
    ..To investigate whether plasma concentrations of flavanones can serve as biomarkers of their intake...
  17. ncbi request reprint Polymorphisms of key enzymes in homocysteine metabolism affect diet responsiveness of plasma homocysteine in healthy women
    M L Silaste
    Department of Internal Medicine, University of Oulu, Kajaanintie 50, FIN 90220 Oulu, Finland
    J Nutr 131:2643-7. 2001
    ..The 844ins68 of CBS gene did not affect plasma tHcy concentrations or diet responsiveness. In conclusion, diet responsiveness of plasma homocysteine may be genetically regulated...
  18. ncbi request reprint Homocysteine as a risk factor for CVD mortality in men with other CVD risk factors: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study
    J K Virtanen
    Research Institute of Public Health, University of Kuopio, Kuopio, Finland
    J Intern Med 257:255-62. 2005
    ..The purpose of the study was to explore the joint effect of increased serum tHcy concentration and other risk factors on the risk of CVD mortality in middle-aged men without a history of heart disease or stroke...