Research Topics
| R NaatanenSummaryCountry: Finland Publications
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Publications
"Primitive intelligence" in the auditory cortexR Naatanen
Cognitive Brain Research Unit, Dept of Psychology, University of Helsinki, Helsinki, Finland
Trends Neurosci 24:283-8. 2001....
Combined mapping of human auditory EEG and MEG responsesM Huotilainen
Department of Psychology, University of Helsinki, Finland
Electroencephalogr Clin Neurophysiol 108:370-9. 1998..In addition, source-current components not detectable by MEG were shown to contribute to the measured EEG signals...
Electromagnetic responses of the human auditory cortex generated by sensory-memory based processing of tone-frequency changesO Korzyukov
Department of Psychology, University of Helsinki, Finland
Neurosci Lett 276:169-72. 1999..This supports the idea that a sensory-memory trace formed in the auditory cortex by preceding repetitive sounds is a necessary precondition for MMN/MMNm elicitation...
Language-specific phoneme representations revealed by electric and magnetic brain responsesR Naatanen
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
Nature 385:432-4. 1997..Whole-head magnetic recordings located the source of this native-language, phoneme-related response enhancement, and thus the language-specific memory traces, in the auditory cortex of the left hemisphere...
The processing of sound duration after left hemisphere stroke: event-related potential and behavioral evidenceT M Ilvonen
Department of Psychology, University of Helsinki, Finland
Psychophysiology 38:622-8. 2001..Especially by recording MMN to monaural stimuli, the discrimination accuracy can be separately determined for the left and right temporal lobes...
Brain activity index of distractibility in normal school-age childrenV Gumenyuk
Cognitive Brain Research Unit, Department of Psychology, P O Box 13, FIN 00014, University of Helsinki, Finland
Neurosci Lett 314:147-50. 2001..Moreover, differences in ERP amplitudes and in their correlations with the reaction times between younger (7-10 years) and older (11-13 years) children indicated developmental changes in attentional brain functions...
Electrophysiological evidence for cross-modal plasticity in humans with early- and late-onset blindnessT Kujala
Department of Psychology, University of Helsinki, Finland
Psychophysiology 34:213-6. 1997..These results suggest that cross-modal reorganization may occur even in the mature human brain...
Increased distractibility by task-irrelevant sound changes in abstinent alcoholicsJ Ahveninen
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
Alcohol Clin Exp Res 24:1850-4. 2000..The neural abnormalities that underlie such deficits in alcoholics were explored with event-related potential (ERP) components that disclosed different phases of detection and orienting to stimulus changes...
Global field power of auditory N1 correlates with impaired verbal-memory performance in human alcoholicsJ Ahveninen
Cognitive Brain Research Unit, Department of Psychology, P O Box 13, FIN 00014 University of, Helsinki, Finland
Neurosci Lett 285:131-4. 2000..5) with impaired memory performance in the alcoholics. The profound change in pre-attentive auditory processing, predicting impaired memory performance, might reflect impaired cerebral inhibitory transmission in alcoholics...
Selective tuning of the left and right auditory cortices during spatially directed attentionK Alho
Cognitive Brain Research Unit, Department of Psychology, P O Box 13, FIN 00014 University of Helsinki, Helsinki, Finland
Brain Res Cogn Brain Res 7:335-41. 1999....
Cortical auditory dysfunction in children with oral clefts: relation with cleft typeR Ceponiene
Department of Psychology, University of Helsinki, Finland
Clin Neurophysiol 110:1921-6. 1999..We investigated persistence of auditory short-term memory (STM) that is implicitly involved in language-specific perception in children with clefts, grouped using fine-graded cleft classification...
Suppression of mismatch negativity by backward masking predicts impaired working-memory performance in alcoholicsJ Ahveninen
Department of Psychology, University of Helsinki, Finland
Alcohol Clin Exp Res 23:1507-14. 1999..Pronounced disruption of memory traces by subsequent distractors may result in impaired behavioral memory performance in alcoholics...
Post-withdrawal changes in middle-latency auditory evoked potentials in abstinent human alcoholicsJ Ahveninen
Department of Psychology, University of Helsinki, Finland
Neurosci Lett 268:57-60. 1999..The present results suggest that the post-withdrawal brain hyperexcitability in the alcoholic brain, gradually recovering with abstinence, could be objectively and non-invasively studied with the MAEP...
Dysfunction of the auditory cortex persists in infants with certain cleft typesR Ceponiene
Department of Psychology, University of Helsinki, Finland
Dev Med Child Neurol 42:258-65. 2000..This pattern parallels known behavioural differences between children with these cleft types. Brain responses to rare sounds, in contrast, had no differentiative power with respect to the cleft type...
The perception of invariant speech features in children with autismT Lepistö
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, P O Box 9, Helsinki FIN 00014, Finland
Biol Psychol 77:25-31. 2008..This suggests that children with autism lose their advantage in phoneme discrimination when the context of the stimuli is speech-like and requires abstracting invariant speech features from varying input...
Atypical pattern of discriminating sound features in adults with Asperger syndrome as reflected by the mismatch negativityT Kujala
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, PO Box 9, Helsinki FIN 00014, Finland
Biol Psychol 75:109-14. 2007..Our results suggest hypersensitive auditory change detection in Asperger syndrome, as reflected in the enhanced MMN for deviant sounds with a gap or shorter duration, and speeded MMN elicitation for frequency changes...
Brain dysfunction in neonates with cleft palate revealed by the mismatch negativityM Cheour
Department of Psychology, University of Helsinki, Finland
Clin Neurophysiol 110:324-8. 1999..The present study aimed at investigating whether the MMN is attenuated already in newborns with cleft palate compared with healthy controls...
Replicability of MEG and EEG measures of the auditory N1/N1m-responseJ Virtanen
Department of Psychology, University of Helsinki, Helsinki University Central Hospital, Finland
Electroencephalogr Clin Neurophysiol 108:291-8. 1998..The results suggest that both MEG and EEG can be used for investigating the simultaneous activity of the left and right auditory cortices independently, MEG being superior in certain experimental setups...
Neuronal populations in the human brain extracting invariant relationships from acoustic varianceP Paavilainen
Department of Psychology, University of Helsinki, Finland
Neurosci Lett 265:179-82. 1999....
Effects of spectral complexity and sound duration on automatic complex-sound pitch processing in humans - a mismatch negativity studyM Tervaniemi
Department of Psychology, Cognitive Brain Research Unit, University of Helsinki, P O Box 13, FIN 00014, Helsinki, Finland
Neurosci Lett 290:66-70. 2000..The prolonged sound duration did not significantly enhance the MMN. This suggests that increased spectral rather than temporal information facilitates pitch processing of spectrally rich sounds...
Maturation of mismatch negativity in infantsM Cheour
Department of Psychology, University of Helsinki, Finland
Int J Psychophysiol 29:217-26. 1998..The mean MMN latency, however, decreased significantly with age, although in 3-month-old infants it was not much longer than in a previous study conducted in adults with the same stimuli...
Dose-dependent suppression by ethanol of transient auditory 40-Hz responseI P Jääskeläinen
Cognitive Brain Research Unit, Department of Psychology, P O Box 13, Meritullinkatu 1, 00014 University of Helsinki, Finland
Psychopharmacology (Berl) 148:132-5. 2000....
Pre-attentive discriminability of sound order as a function of tone duration and interstimulus interval: a mismatch negativity studyM Tervaniemi
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
Audiol Neurootol 4:303-10. 1999....
Mismatch negativity and behavioural discrimination in humans as a function of the magnitude of change in sound durationM Jaramillo
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland, PO Box 13, FIN 00014, Helsinki, Finland
Neurosci Lett 290:101-4. 2000..Behavioural detection paralleled the MMN responses, suggesting a link between the processes underlying MMN and behavioural measures...
Harmonic partials facilitate pitch discrimination in humans: electrophysiological and behavioral evidenceM Tervaniemi
Department of Psychology, University of Helsinki, Finland
Neurosci Lett 279:29-32. 2000..Together these data indicate that pre-attentive and attentive pitch discrimination is facilitated with spectrally rich sounds in comparison to pure sinusoidal tones...
Basic auditory dysfunction in dyslexia as demonstrated by brain activity measurementsT Kujala
Department of Psychology, University of Helsinki, Finland
Psychophysiology 37:262-6. 2000..This failure can be traced to early cortical mechanisms that process auditory information independently of attention...
Speech- and sound-segmentation in dyslexia: evidence for a multiple-level cortical impairmentT Kujala
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, PO Box 9, 00014 Helsinki, Finland
Eur J Neurosci 24:2420-7. 2006....
Superior formation of cortical memory traces for melodic patterns in musiciansM Tervaniemi
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, 00014 Helsinki, Finland
Learn Mem 8:295-300. 2001....
Electromagnetic recordings reveal latency differences in speech and tone processing in humansH Tiitinen
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, PO Box 13 Meritullinkatu 1, FIN 00014, Helsinki, Finland
Brain Res Cogn Brain Res 8:355-63. 1999..The findings are discussed in relation to previous observations on cortical processing of sinusoidal and vowel sounds and with regard to the glottal excitation in speech processing...
The musical brain: brain waves reveal the neurophysiological basis of musicality in human subjectsM Tervaniemi
Department of Psychology, University of Helsinki, Finland
Neurosci Lett 226:1-4. 1997....
Background acoustic noise and the hemispheric lateralization of speech processing in the human brain: magnetic mismatch negativity studyY Shtyrov
Department of Psychology, University of Helsinki, Finland
Neurosci Lett 251:141-4. 1998..However, in noisy conditions the involvement of the left hemisphere's auditory cortex in speech discrimination is considerably decreased, while that of the right hemisphere increases...
Effects of naltrexone and ethanol on auditory event-related brain potentialsI P Jääskeläinen
Department of Psychology, University of Helsinki, Finland
Alcohol 15:105-11. 1998..Furthermore, the N2b amplitude was significantly suppressed in the interaction condition, suggesting attentional impairment...
Test-retest reliability of mismatch negativity for duration, frequency and intensity changesM Tervaniemi
Department of Psychology, University of Helsinki, Finland
Clin Neurophysiol 110:1388-93. 1999..The test-retest reliabilities of the mismatch negativity (MMN) elicited by deviances in sound duration, frequency, and intensity were compared...
Benzodiazepine temazepam suppresses the transient auditory 40-Hz response amplitude in humansI P Jääskeläinen
Department of Psychology, University of Helsinki, Finland
Neurosci Lett 268:105-7. 1999..This suggests involvement of GABA(A) receptors in transient auditory 40-Hz response generation, however, not in the attentive modulation of the 40-Hz response...
Mismatch negativity (MMN): perspectives for applicationR Naatanen
Cognitive Brain Research Unit, P O Box 13 Meritullinkatu 1, 00014 University of Helsinki and the Academy of Finland, Helsinki, Finland
Int J Psychophysiol 37:3-10. 2000..The MMN can be measured in the absence of attention and without any task requirements, which makes it particularly suitable for testing different clinical populations and infants...
Separation of contamination caused by coil clicks from responses elicited by transcranial magnetic stimulationH Tiitinen
Department of Psychology, University of Helsinki, Finland
Clin Neurophysiol 110:982-5. 1999..Furthermore, clicks were found to interact with simultaneously presented auditory sinewave stimuli, resulting in an amplitude decrease in the auditory N1 response...
Children's performance on pseudoword repetition depends on auditory trace quality: evidence from event-related potentialsR Ceponiene
Department of Psychology, University of Helsinki, Finland
Dev Psychol 35:709-20. 1999..Thus, the accuracy of auditory-sensory processing seems to affect phonological short-term representations in school-age children and therefore may play a role in vocabulary development...
The mismatch negativity as an index of temporal processing in auditionT Kujala
Cognitive Brain Research Unit, Department of Psychology, P O Box 13, University of Helsinki, FIN 00014 Helsinki, Finland
Clin Neurophysiol 112:1712-9. 2001..The relation of the mismatch negativity (MMN) elicitation with behavioral stimulus discrimination as well as the replicability of the MMN was evaluated for intervals between paired tones...
Central auditory processing of durational changes in complex speech patterns by newborns: an event-related brain potential studyE Kushnerenko
Cognitive Brain Research Unit, Department of Psychology, P O Box 13, 00014 University of Helsinki, Finland
Dev Neuropsychol 19:83-97. 2001..The first negative wave peaked at about 150 msec and the second at about 350 msec after the change onset. At least one negative deflection, which was interpreted as evidence for stimulus change-detection, was observed in every infant...
Pre-attentive processing of spectrally complex sounds with asynchronous onsets: an event-related potential study with human subjectsM Tervaniemi
Department of Psychology, University of Helsinki, Finland
Neurosci Lett 227:197-200. 1997..In summary, the present results support the existence of pre-perceptual integration mechanism of 100-200 ms duration and emphasize its importance in switching attention towards the stimulus change...
Psychosocial stress attenuates general sound processing and duration change detectionV L Simoens
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Helsinki, Finland
Psychophysiology 44:30-8. 2007..We found that psychosocial stressor anticipation attenuates both general and deviance-specific sound processing, suggesting that cortisol interferes with cortical memory-trace formation...
MEG-compatible multichannel EEG electrode arrayJ Virtanen
Department of Psychology, University of Helsinki, Finland
Electroencephalogr Clin Neurophysiol 99:568-70. 1996..The electrode array is magnetically compatible with MEG and the low-profile electrodes consume minimal space inside the magnetometer...
The mismatch negativity (MMN) in basic research of central auditory processing: a reviewR Naatanen
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Helsinki, Finland
Clin Neurophysiol 118:2544-90. 2007..In addition, the MMN enables one to establish the brain processes underlying the initiation of attention switch to, conscious perception of, sound change in an unattended stimulus stream...
Auditory perception and attention as reflected by the brain event-related potentials in children with Asperger syndromeT Lepistö
Cognitive Brain Research Unit, Department of Psychology, P O Box 9, FIN 00014 University of Helsinki, Finland
Clin Neurophysiol 117:2161-71. 2006..We investigated auditory-discrimination and orienting in children with AS using an event-related potential (ERP) paradigm that was previously applied to children with autism...
Biopotential amplifier for simultaneous operation with biomagnetic instrumentsJ Virtanen
Department of Psychology, University of Helsinki, Finland
Med Biol Eng Comput 35:402-8. 1997..Special care is taken to analyse the coupling mechanisms of mains interference to the amplifier. Over 170 simultaneous electric and magnetic recordings have been performed using the system in a hospital environment...
The mismatch negativity in evaluating central auditory dysfunction in dyslexiaT Kujala
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, P O Box 13, FIN 00014 Helsinki, Finland
Neurosci Biobehav Rev 25:535-43. 2001..Furthermore, the MMN holds promise of showing plastic changes in the brain of dyslexic individuals underlying the alleviation or remediation of dyslexia in the course of a successful training programme...
Effects of haloperidol on selective attention: a combined whole-head MEG and high-resolution EEG studyS Kahkonen
BioMag Laboratory, Medical Engineering Centre, Helsinki University Central Hospital, Helsinki, Finland
Neuropsychopharmacology 25:498-504. 2001..Taken together, haloperidol seemed to induce functional changes in neural networks accounting for both selective and involuntary attention, suggesting modulation of these functions by dopamine D2 receptors...
Plastic neural changes and reading improvement caused by audiovisual training in reading-impaired childrenT Kujala
Cognitive Brain Research Unit, Department of Psychology, P O Box 13, University of Helsinki, FIN 00014 Helsinki, Finland
Proc Natl Acad Sci U S A 98:10509-14. 2001..Moreover, the fact that the present training effects were obtained by using a program including no linguistic material indicates that dyslexia is at least partly based on a general auditory perceptual deficit...
Preattentive extraction of abstract feature conjunctions from auditory stimulation as reflected by the mismatch negativity (MMN)P Paavilainen
Department of Psychology, University of Helsinki, Finland
Psychophysiology 38:359-65. 2001..The results demonstrate that preattentive processing of auditory stimuli extends to unexpectedly complex relationships between the stimulus features...
Lateralized automatic auditory processing of phonetic versus musical information: a PET studyM Tervaniemi
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
Hum Brain Mapp 10:74-9. 2000..The data thus indicate that automatic activation of lateralized neuronal circuits requires sound comparison based on short-term sound representations...
Independent processing of changes in auditory single features and feature conjunctions in humans as indexed by the mismatch negativityR Takegata
Department of Psychology, University of Helsinki, Finland
Neurosci Lett 266:109-12. 1999..This result indicates that changes in simple stimulus features and conjunction of features are processed independently by the automatic sound change detection system indexed by MMN...
Mismatch negativity--the measure for central sound representation accuracyR Naatanen
Department of Psychology, University of Helsinki, Finland
Audiol Neurootol 2:341-53. 1997..This accuracy, which can be measured separately for the different features of the sound, determines the individual's sound discrimination accuracy in normal and various pathological conditions...
Dose-related effects of memantine on a mismatch negativity-like response in anesthetized ratsD Tikhonravov
Neuroscience Unit, Institute of Biomedicine Physiology, University of Helsinki, Helsinki, Finland
Neuroscience 167:1175-82. 2010..The high dose of memantine, in contrast, blocked the generation of the auditory MMN-like response. The findings suggest that memantine may, with appropriate doses, facilitate already this early stage of auditory processing...
The additivity of the auditory feature analysis in the human brain as indexed by the mismatch negativity: 1+1 approximately 2 but 1+1+1<3P Paavilainen
Cognitive Brain Research Unit, Department of Psychology, P O Box 13, FIN 00014 University of Helsinki, Helsinki, Finland
Neurosci Lett 301:179-82. 2001..The double-deviant MMNs were found to be additive but the triple-deviant MMN was clearly underadditive. The results suggest complex interactions between brain processes involved in analyzing several simultaneous deviant features...
Enhanced brain activity preceding voluntary movement in early blind humansA Lehtokoski
Department of Psychology, University of Helsinki, Finland
Neurosci Lett 253:155-8. 1998..The results suggest functional changes in the blind subjects' brain activity, presumably, in the cortical areas involved in preparation and initiation of voluntary movement...
The mismatch negativity (MMN)--a unique window to disturbed central auditory processing in ageing and different clinical conditionsR Naatanen
Institute of Psychology, University of Tartu, Tartu, Estonia, Finland
Clin Neurophysiol 123:424-58. 2012..In fact, MMN deficiency appears to index cognitive decline irrespective of the specific symptomatologies and aetiologies of the different disorders involved...
Instrumentation for the measurement of electric brain responses to transcranial magnetic stimulationJ Virtanen
Department of Psychology, University of Helsinki, Finland
Med Biol Eng Comput 37:322-6. 1999..The TMS-compatible multichannel EEG system makes it possible to locate TMS-evoked electric activity in the brain...
The perception of speech sounds by the human brain as reflected by the mismatch negativity (MMN) and its magnetic equivalent (MMNm)R Naatanen
Cognitive Brain Research Unit CBRU, Department of Psychology, University of Helsinki, Finland
Psychophysiology 38:1-21. 2001....
Selective tuning of cortical sound-feature processing by language experienceM Tervaniemi
Cognitive Brain Research Unit, Department of Psychology, University of Helsinki, Finland
Eur J Neurosci 23:2538-41. 2006..This result, obtained both by behavioural and neural indices at attentive and automatic levels of processing, indicates precise feature-specific tuning of the auditory-cortex functions by the mother tongue...
