Research Topics
| J V LaurilaSummaryCountry: Finland Publications
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Detail Information
Publications
Matrix-metalloproteinase-2, -8 and -9 in serum and skin blister fluid in patients with severe sepsisFiia P Gäddnäs
Department of Anesthesiology, Division of Intensive Care, Oulu University Hospital, Kajaanintie 50, Oulu, Finland
Crit Care 14:R49. 2010..The aim of this study was to investigate the timely development of serum and skin MMP-2, -8 and -9 levels in human severe sepsis and their association with disease severity and mortality...
Confusion assessment method in the diagnostics of delirium among aged hospital patients: would it serve better in screening than as a diagnostic instrument?J V Laurila
Helsinki University Hospital, Department of Medicine, Geriatric Clinic, Helsinki, Finland
Int J Geriatr Psychiatry 17:1112-9. 2002..The Confusion Assessment Method (CAM) is an easy, four-step algorithmic diagnostic test developed to detect delirium...
Detection and documentation of dementia and delirium in acute geriatric wardsJouko V Laurila
Department of Medicine, Helsinki University Hospital, Geriatric Clinic, Helsinki, Finland
Gen Hosp Psychiatry 26:31-5. 2004..3%) in medical records. In 64/77 (83.1%) cases signs of confusion were recorded in nurses' notes. Poor detection and documentation may lead to undertreatment of both disorders...
Behavioral symptoms and the administration of psychotropic drugs to aged patients with dementia in nursing homes and in acute geriatric wardsK H Pitkala
Department of Medicine, Geriatric Clinic, Helsinki University Hospital, Finland
Int Psychogeriatr 16:61-74. 2004..To describe the prevalence of various psychiatric and behavioral symptoms among patients with dementia in nursing homes and acute geriatric wards and to investigate the administration of psychotropic medications to these patients...
Anticholinergic drugs and their effects on delirium and mortality in the elderlyM J Luukkanen
Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland
Dement Geriatr Cogn Disord Extra 1:43-50. 2011..To investigate the use of drugs with anticholinergic properties (DAPs) and their associations with delirium and mortality among elderly patients with comorbidities...
Delirium among patients with and without dementia: does the diagnosis according to the DSM-IV differ from the previous classifications?Jouko V Laurila
Department of Medicine, Helsinki University Hospital, Geriatric Clinic, Helsinki, Finland
Int J Geriatr Psychiatry 19:271-7. 2004..It is not known how DSM-IV classification, compared with the DSM-III, DSM-III-R, and ICD-10, identifies delirium among individuals with and without dementia and whether the symptom profiles differ between these two subgroups...
Neither atypical nor conventional antipsychotics increase mortality or hospital admissions among elderly patients with dementia: a two-year prospective studyMinna M Raivio
Memory Research and Treatment Centers Finland Medical Center Hemo Oy, Lahti, Finland
Am J Geriatr Psychiatry 15:416-24. 2007..Antipsychotics are widely used to manage behavioral disorders in patients with dementia. Recently, serious concerns have been raised about the stroke and mortality risk of atypical antipsychotics when administered to patients with dementia...
Impact of different diagnostic criteria on prognosis of delirium: a prospective studyJouko V Laurila
Geriatric Clinic, Department of Medicine, Helsinki University Hospital, Helsinki, Finland
Dement Geriatr Cogn Disord 18:240-4. 2004..The DSM-IV has simplified the criteria of delirium. It identifies new, acutely ill and relatively nondependent subjects as delirious who share the poor prognosis of patients diagnosed with the previous criteria...
The impact of different diagnostic criteria on prevalence rates for deliriumJouko V Laurila
Geriatric Clinic, Department of Medicine, Helsinki University Hospital, HUS, Finland
Dement Geriatr Cogn Disord 16:156-62. 2003..The DSM-IV and ICD-10 had the largest number of patients not overlapping with any other diagnostic group. The newest DSM-IV classification found more cases of delirium especially among acutely ill, hospitalized patients...
Multicomponent geriatric intervention for elderly inpatients with delirium: effects on costs and health-related quality of lifeKaisu H Pitkala
Unit of General Practice, University of Helsinki, Finland
J Gerontol A Biol Sci Med Sci 63:56-61. 2008..We studied the effects of multicomponent geriatric treatment on costs of care and HRQoL in delirious inpatients...
The European delirium associationAlasdair M J MacLullich
Geriatric Medicine, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, Scotland
J Psychosom Res 62:397-8. 2007
Use of inappropriate medications and their prognostic significance among in-hospital and nursing home patients with and without dementia in FinlandMinna M Raivio
Department of General Internal Medicine and Geriatrics, University of Helsinki, Finland
Drugs Aging 23:333-43. 2006..This study examines the use of inappropriate drugs and their impact on mortality and use of health services among Finnish elderly nursing home and hospital patients. Patients with dementia were studied as a special subgroup...
Multicomponent geriatric intervention for elderly inpatients with delirium: a randomized, controlled trialKaisu H Pitkala
The Central Union for the Welfare of the Aged, Malmin Kauppatie 26, 00700 Helsinki, Finland
J Gerontol A Biol Sci Med Sci 61:176-81. 2006..Treatment is mainly based on common sense with wide variations in practice. We investigated whether intensified, multicomponent geriatric treatment could improve the prognosis of delirious patients...
Prognostic significance of delirium in frail older peopleKaisu H Pitkala
Department of Medicine, Geriatric Clinic, Helsinki University Hospital, Helsinki, Finland
Dement Geriatr Cogn Disord 19:158-63. 2005..86, 95% CI 1.1-3.1), at 2 years (OR 1.76, 95% CI 1.1-2.8), and for permanent institutionalization (OR 2.45, 95% CI 1.2-4.9). Delirious patients with prior dementia tended to have a better prognosis than those without...
Psychotropic medication and stroke outcomeMinna M Raivio
Am J Psychiatry 162:1027; author reply 1027-8. 2005
