S M Lehto

Summary

Affiliation: Kuopio University Hospital
Country: Finland

Publications

  1. doi request reprint Low serum HDL-cholesterol levels are associated with long symptom duration in patients with major depressive disorder
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital, PO Box 1777, FIN 70210 Kuopio, Finland
    Psychiatry Clin Neurosci 64:279-83. 2010
  2. pmc Biological and other health related correlates of long-term life dissatisfaction burden
    Teemu Rissanen
    Department of Psychiatry, Kuopio University Hospital, Kuopio, Finland
    BMC Psychiatry 13:202. 2013
  3. doi request reprint Dietary zinc intake and the risk of depression in middle-aged men: A 20-year prospective follow-up study
    Soili M Lehto
    Department of Psychiatry, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland Electronic address
    J Affect Disord 150:682-5. 2013
  4. doi request reprint Serum adipokine levels in adults with a history of childhood maltreatment
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital, Kuopio, Finland
    Prog Neuropsychopharmacol Biol Psychiatry 37:217-21. 2012
  5. pmc Elevated levels of serum IL-5 are associated with an increased likelihood of major depressive disorder
    Antti Pekka Elomaa
    Department of Psychiatry, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland
    BMC Psychiatry 12:2. 2012
  6. pmc Unemployment and ill health: a connection through inflammation?
    Jukka Hintikka
    Department of Psychiatry, Kuopio University Hospital and Department of Clinical Medicine, University of Kuopio, FI 70210 KUOPIO, Finland
    BMC Public Health 9:410. 2009
  7. pmc Long term life dissatisfaction and subsequent major depressive disorder and poor mental health
    Teemu Rissanen
    Dept of Psychiatry, Kuopio University Hospital, Kuopio, Finland
    BMC Psychiatry 11:140. 2011
  8. pmc Depressive symptoms during rehabilitation period predict poor outcome of lumbar spinal stenosis surgery: a two-year perspective
    Sanna Sinikallio
    Department of Rehabilitation, Kuopio University Hospital, Kuopio, Finland
    BMC Musculoskelet Disord 11:152. 2010
  9. doi request reprint Serum IL-7 and G-CSF in major depressive disorder
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital and University of Eastern Finland, 70210 Kuopio, Finland
    Prog Neuropsychopharmacol Biol Psychiatry 34:846-51. 2010
  10. pmc Elevated depressive symptoms and compositional changes in LDL particles in middle-aged men
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital, 70210, Kuopio, Finland
    Eur J Epidemiol 25:403-9. 2010

Detail Information

Publications25

  1. doi request reprint Low serum HDL-cholesterol levels are associated with long symptom duration in patients with major depressive disorder
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital, PO Box 1777, FIN 70210 Kuopio, Finland
    Psychiatry Clin Neurosci 64:279-83. 2010
    ..The purpose of the present study was to examine whether the association between depression and the serum high-density lipoprotein cholesterol (HDL-C) is modified by symptom duration...
  2. pmc Biological and other health related correlates of long-term life dissatisfaction burden
    Teemu Rissanen
    Department of Psychiatry, Kuopio University Hospital, Kuopio, Finland
    BMC Psychiatry 13:202. 2013
    ..The aim of this study was to investigate the biological correlates along with other health-related factors of long-term life dissatisfaction in a population-based sample...
  3. doi request reprint Dietary zinc intake and the risk of depression in middle-aged men: A 20-year prospective follow-up study
    Soili M Lehto
    Department of Psychiatry, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland Electronic address
    J Affect Disord 150:682-5. 2013
    ..This study examined the association between dietary zinc intake and depression in a prospective setting in initially depression-free men during a 20-year follow-up...
  4. doi request reprint Serum adipokine levels in adults with a history of childhood maltreatment
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital, Kuopio, Finland
    Prog Neuropsychopharmacol Biol Psychiatry 37:217-21. 2012
    ..This may lead to a lowered anti-inflammatory buffer capacity, which can, in turn, increase the susceptibility to physical and psychological states characterized by pronounced pro-inflammation...
  5. pmc Elevated levels of serum IL-5 are associated with an increased likelihood of major depressive disorder
    Antti Pekka Elomaa
    Department of Psychiatry, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland
    BMC Psychiatry 12:2. 2012
    ..Nevertheless, relatively little is known about the role of the T-helper (Th)-2 effector cytokines interleukin (IL)-5 and IL-13 in MDD...
  6. pmc Unemployment and ill health: a connection through inflammation?
    Jukka Hintikka
    Department of Psychiatry, Kuopio University Hospital and Department of Clinical Medicine, University of Kuopio, FI 70210 KUOPIO, Finland
    BMC Public Health 9:410. 2009
    ..Acute and chronic psychosocial stress can induce pronounced changes in human immune responses. In this study we tested our hypothesis that stress-induced low-grade tissue inflammation is more prevalent among the unemployed...
  7. pmc Long term life dissatisfaction and subsequent major depressive disorder and poor mental health
    Teemu Rissanen
    Dept of Psychiatry, Kuopio University Hospital, Kuopio, Finland
    BMC Psychiatry 11:140. 2011
    ..Early indicators of poor mental health in general population are needed. This study examined the relationship between long-term life dissatisfaction and subsequent mental health, including major depressive disorder...
  8. pmc Depressive symptoms during rehabilitation period predict poor outcome of lumbar spinal stenosis surgery: a two-year perspective
    Sanna Sinikallio
    Department of Rehabilitation, Kuopio University Hospital, Kuopio, Finland
    BMC Musculoskelet Disord 11:152. 2010
    ..In this prospective clinical study the predictive value of preoperative and postoperative depressive symptoms with respect to the surgery outcome is reported...
  9. doi request reprint Serum IL-7 and G-CSF in major depressive disorder
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital and University of Eastern Finland, 70210 Kuopio, Finland
    Prog Neuropsychopharmacol Biol Psychiatry 34:846-51. 2010
    ..The G-CSF levels did not differ between the two groups. The lowering of the serum levels of IL-7, a regulator of T cell homeostasis, in MDD subjects may underlie the depression-related impaired T cell function...
  10. pmc Elevated depressive symptoms and compositional changes in LDL particles in middle-aged men
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital, 70210, Kuopio, Finland
    Eur J Epidemiol 25:403-9. 2010
    ..Our findings suggest that greater small-particle LDL levels are not associated with depression, and are thus unlikely to underlie the association between cardiovascular risk and depression...
  11. doi request reprint Serum anti-inflammatory markers in general population subjects with elevated depressive symptoms
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital, 70210 Kuopio, Finland
    Neurosci Lett 484:201-5. 2010
    ..001). The significance of IL-6 alterations did not persist in the same model. The pronounced secretion of anti-inflammatory marker IL-1 RA may reflect the presence of compensatory mechanisms during a depression-related inflammatory state...
  12. ncbi request reprint Changes in midbrain serotonin transporter availability in atypically depressed subjects after one year of psychotherapy
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital, 70210 Kuopio, Finland
    Prog Neuropsychopharmacol Biol Psychiatry 32:229-37. 2008
    ..The effect of psychotherapy on neurotransmitter transporter functions has never been recorded in depressed subjects...
  13. doi request reprint Low HDL cholesterol associates with major depression in a sample with a 7-year history of depressive symptoms
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital and University of Kuopio, 70210 Kuopio, Finland
    Prog Neuropsychopharmacol Biol Psychiatry 32:1557-61. 2008
    ..049). These findings suggest that compared with the healthy controls, those with long-term depression may have lower HDL-C values and higher atherogenic indices...
  14. doi request reprint Temporal cortex dopamine D2/3 receptor binding in major depression
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital, Kuopio, Finland
    Psychiatry Clin Neurosci 62:345-8. 2008
    ..Dopaminergic abnormalities may be present in the temporal cortices of major depressives...
  15. doi request reprint Serum adiponectin and resistin levels in major depressive disorder
    S M Lehto
    Department of Psychiatry, Kuopio University Hospital and University of Kuopio, Kuopio, Finland
    Acta Psychiatr Scand 121:209-15. 2010
    ..To examine the role of the adipose-tissue-derived low-grade inflammation markers adiponectin and resistin in major depressive disorder (MDD) in a population-based sample...
  16. doi request reprint Serum chemokine levels in major depressive disorder
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital and University of Kuopio, 70210 Kuopio, Finland
    Psychoneuroendocrinology 35:226-32. 2010
    ..To examine the role of chemokines of two major chemokine families, CC and CXC, in major depressive disorder (MDD) in a population-based sample...
  17. doi request reprint Midbrain serotonin and striatum dopamine transporter binding in double depression: a one-year follow-up study
    Soili M Lehto
    Department of Psychiatry, Kuopio University Hospital, 70210 Kuopio, Finland
    Neurosci Lett 441:291-5. 2008
    ..However, low striatum [123I] nor-beta-CIT binding, a marker of DAT binding, may be associated with a longer illness duration in dysthymia...
  18. doi request reprint Association of depressive symptoms and metabolic syndrome in men
    H Viinamaki
    Institute of Clinical Medicine, University of Kuopio, Kuopio University Hospital, Kuopio, Finland
    Acta Psychiatr Scand 120:23-9. 2009
    ..To explore the relationship between several indicators of depression and metabolic syndrome (MetS)...
  19. doi request reprint How does lifestyle intervention affect depressive symptoms? Results from the Finnish Diabetes Prevention Study
    A Ruusunen
    Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland
    Diabet Med 29:e126-32. 2012
    ..To assess the effect of lifestyle intervention on depressive symptoms during a 36-month randomized clinical trial designed to prevent Type 2 diabetes...
  20. doi request reprint Population-based comparison of health-related quality of life between healthy subjects and those with specific psychiatric or somatic diseases
    Tarja Saharinen
    Department of Nursing Science, University of Eastern Finland, and Kuopio University Hospital, Kuopio Psychiatric Center, Kuopio, Finland
    Perspect Psychiatr Care 47:66-73. 2011
    ..The purpose of this study was to compare health-related quality of life (HRQL) of healthy subjects and those with psychiatric or somatic diseases...
  21. doi request reprint Hypogonadism, decreased sexual desire, and long-term depression in middle-aged men
    Jukka Hintikka
    Institute of Clinical Medicine, University of Kuopio, Kuopio, Finland
    J Sex Med 6:2049-57. 2009
    ..In middle-aged men, the associations between long-term depressive symptoms and circulating testosterone levels are poorly known, although it is known that testosterone levels decrease with age...
  22. doi request reprint Coexistence of pain and depression predicts poor 2-year surgery outcome among lumbar spinal stenosis patients
    Sanna Sinikallio
    Department of Rehabilitation, Kuopio University Hospital, Kuopio, Finland
    Nord J Psychiatry 64:391-6. 2010
    ..Lumbar spinal stenosis is a common cause of back and leg pain with the most severe cases treated surgically. Regarding the surgery outcome, the importance of early postoperative depression and pain is unknown...
  23. doi request reprint Depressive symptoms predict postoperative disability among patients with lumbar spinal stenosis: a two-year prospective study comparing two age groups
    Sanna Sinikallio
    Department of Rehabilitation 2981, Kuopio University Hospital, Tarinan sairaala, Siilinjärvi, 71800 Finland
    Disabil Rehabil 32:462-8. 2010
    ..To examine the importance of preoperative and recovery phase depressive symptoms in two age groups of patients with lumbar spinal stenosis (LSS) with respect to surgery outcome 2 years postoperatively...
  24. doi request reprint Alexithymia is associated with increased cardiovascular mortality in middle-aged Finnish men
    Tommi Tolmunen
    Department of Psychiatry, Kuopio University Hospital, FIN 70211 Kuopio, Finland
    Psychosom Med 72:187-91. 2010
    ..To explore the associations between alexithymia and increased somatic morbidity. The mechanisms underlying these associations, however, are still unclear. Furthermore, data on the association between alexithymia and mortality are scarce...
  25. doi request reprint Is alexithymia a risk factor for major depression, personality disorder, or alcohol use disorders? A prospective population-based study
    Kirsi Honkalampi
    Department of Psychiatry, Kuopio University Hospital, Kuopio, Finland
    J Psychosom Res 68:269-73. 2010
    ..The aim of this 7-year follow-up study was to examine whether alexithymia predicts subsequent major depression, personality disorder, or alcohol use disorders in a population-based sample...