Research Topics
Genomes and GenesSpecies | L Keski-NisulaSummaryAffiliation: Kuopio University Hospital Country: Finland Publications
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Detail Information
Publications
Maternal intrapartum antibiotics and decreased vertical transmission of Lactobacillus to neonates during birthLeea Keski-Nisula
Department of Obstetrics and Gynaecology, Kuopio University Hospital, Kuopio, Finland Department of Environmental Health, National Institute for Health and Welfare, Kuopio, Finland
Acta Paediatr 102:480-5. 2013..To estimate the transmission of maternal vaginal microbiota to neonates during term delivery, focusing on Lactobacillus flora in relation to various obstetric clinical factors...
Umbilical artery pH values at birth and risk of asthma at 5 to 6 years of ageL Keski-Nisula
Department of Environmental Health, National Institute for Health and Welfare, Kuopio, Finland
J Investig Allergol Clin Immunol 22:48-54. 2012..Intrapartum factors may have a role in the development of asthma and allergic diseases among offspring...
Production of interleukin-5, -10 and interferon-γ in cord blood is strongly associated with the season of birthL Keski-Nisula
Department of Environmental Health, National Institute for Health and Welfare, Kuopio, Finland
Clin Exp Allergy 40:1658-68. 2010..The effect of labour and different labour-related factors on the cord blood (CB) cell cytokine production is still relatively unknown...
Birth-related factors and doctor-diagnosed wheezing and allergic sensitization in early childhoodL Keski-Nisula
Department of Environmental Health, National Institute for Health and Welfare, Kuopio, Finland
Allergy 65:1116-25. 2010..To investigate the associations between clinical obstetric factors during birth and doctor-diagnosed wheezing and allergic sensitization during early childhood...
Pre-eclampsia, placental abruption and increased risk of atopic sensitization in male adolescent offspringLeea Keski-Nisula
Department of Environmental Health, National Institute for Health and Welfare, Kuopio, Finland
Am J Reprod Immunol 62:293-300. 2009..The aim of this study was to investigate maternal pre-eclampsia (PE), placental abruption (PA) and atopy among offspring...
Intrauterine bacterial growth at birth and risk of asthma and allergic sensitization among offspring at the age of 15 to 17 yearsLeea Keski-Nisula
Environmental Health Department, National Institute for Health and Welfare, Kuopio, Finland
J Allergy Clin Immunol 123:1305-11. 2009..Microbial colonization of the airways and intestine during birth might have an effect on the risk of asthma and allergic diseases later in life...
No association between placental weight or ratio at birth and risk of atopy, hay fever, or asthma at the age of 31 yearsL Keski-Nisula
Environmental Epidemiology Unit, National Public Health Institute, Kuopio, Finland
J Investig Allergol Clin Immunol 17:416-7. 2007
M385T polymorphism in the factor V gene, but not Leiden mutation, is associated with placental abruption in Finnish womenE Jaaskelainen
Department of Obstetrics and Gynecology, Kuopio University Hospital, 70211 Kuopio, Finland
Placenta 25:730-4. 2004..519 (95% CI 0.272-0.987). We conclude that T385 is less frequent among the patient group than in the control group. The M385T variant in the factor V gene other than the Leiden mutation may play a role in disease susceptibility...
Vacuum-assisted delivery is associated with late-onset asthmaL Keski-Nisula
Environmental Health Department, National Institute for Health and Welfare, Kuopio, Finland
Allergy 64:1530-8. 2009..Perinatal factors during delivery might modulate fetal immunological development and thereby be associated with the development of allergic diseases and asthma later...
Farming environment and prevalence of atopy at age 31: prospective birth cohort study in FinlandJ Lampi
Department of Environmental Health, National Institute for Health and Welfare, Kuopio, Finland
Clin Exp Allergy 41:987-93. 2011..Cross-sectional studies have shown an association between the farming environment and a decreased risk of atopic sensitization, mainly related to contact with farm animals in the childhood...
Exposure to microbial agents in house dust and wheezing, atopic dermatitis and atopic sensitization in early childhood: a birth cohort study in rural areasA M Karvonen
Department of Environmental Health, National Institute for Health and Welfare, Kuopio, Finland
Clin Exp Allergy 42:1246-56. 2012..Early-life exposure to environmental microbial agents may be associated with development of wheezing and allergic diseases...
Polymorphism of the interleukin 1 receptor antagonist (IL1Ra) gene and placental abruptionE Jaaskelainen
Department of Obstetrics and Gynaecology, University Hospital of Kuopio, Kuopio 70211, Finland
J Reprod Immunol 79:58-62. 2008..4%) and the general population (1.0%) but the difference was not statistically significant. We conclude that there is no significant difference in IL1Ra polymorphisms between patients with and without placental abruption...
Does the pill make a difference? Previous maternal use of contraceptive pills and allergic diseases among offspringL Keski-Nisula
Environmental Epidemiology Unit, National Public Health Institute, Kuopio, Finland
Allergy 61:1467-72. 2006..Maternal use of oral contraceptive pills (OCPs) might increase the prevalence of allergic diseases among offspring. The aim of the study was to clarify if there are differences between OCP types in this association...
Angiographically guided utero-placental gene transfer in rabbits with adenoviruses, plasmid/liposomes and plasmid/polyethyleneimine complexesA Heikkilä
AI Virtanen Institute, University of Kuopio, Kuopio, Finland
Gene Ther 8:784-8. 2001..Therefore, if gene therapy is developed for the treatment of placental disorders, the gene-vector combination should not be harmful to the fetus and the expression of the transgene should only occur in placenta...
