Research Topics
| Reetta KalviainenSummaryAffiliation: Kuopio University Hospital Country: Finland Publications
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Detail Information
Publications
Long-term cognitive and EEG effects of tiagabine in drug-resistant partial epilepsyR Kalviainen
Department of Neurology, University Hospital of Kuopio, Finland
Epilepsy Res 25:291-7. 1996..7 mg/day, range 30-80 mg/day) and after 18-24 months (mean dose 67.6 mg/day, range 24-80 mg/day). The daily dosages in the long-term follow-up of the present study are higher than in the previous reports...
Status epilepticus treatment guidelinesReetta Kalviainen
Department of Neurology, Kuopio Epilepsy Center, Kuopio University Hospital, Kuopio, Finland
Epilepsia 48:99-102. 2007
Clinical picture of EPM1-Unverricht-Lundborg diseaseReetta Kalviainen
Kuopio Epilepsy Center, Department of Neurology, Kuopio University Hospital, Kuopio, Finland
Epilepsia 49:549-56. 2008..EPM1 patients need lifelong clinical follow-up, including evaluation of the drug-treatment and comprehensive rehabilitation...
Juvenile-onset neuronal ceroid lipofuscinosis with infantile CLN1 mutation and palmitoyl-protein thioesterase deficiencyR Kalviainen
Department of Neurology, Kuopio Epilepsy Center, Kuopio University Hospital and University of Kuopio, Kuopio, Finland
Eur J Neurol 14:369-72. 2007....
Optimizing treatment of epilepsy during pregnancyReetta Kalviainen
Kuopio Epilepsy Center, Department of Neurology, University Hospital of Kuopio, Kuopio, Finland
Neurology 67:S59-63. 2006..With proper management before conception, during pregnancy, and after birth, the vast majority of pregnancies in women with active epilepsy will have a favorable outcome...
Refractory generalised convulsive status epilepticus : a guide to treatmentReetta Kalviainen
Department of Neurology, Kuopio University Hospital and University of Kuopio, Kuopio, Finland
CNS Drugs 19:759-68. 2005....
Vigabatrin, a gabaergic antiepileptic drug, causes concentric visual field defectsR Kalviainen
Department of Neurology, University Hospital of Kuopio, Finland
Neurology 53:922-6. 1999..To determine whether there is a causal link between vigabatrin treatment and concentric visual field defects and to evaluate the prevalence of these visual field constrictions...
Visual field defects with vigabatrin: epidemiology and therapeutic implicationsR Kalviainen
University Hospital of Kuopio and University of Kuopio, Finland
CNS Drugs 15:217-30. 2001....
Do recurrent seizures cause neuronal damage? A series of studies with MRI volumetry in adults with partial epilepsyReetta Kalviainen
Department of Neurology, Kuopio University Hospital, University of Kuopio, Kuopio, Finland
Prog Brain Res 135:279-95. 2002..Future research should address strategies for disease-modifying therapies and ultimately remission of the epileptic process...
Tiagabine: a new therapeutic option for people with intellectual disability and partial epilepsyR Kalviainen
Department of Neurology, University Hospital of Kuopio, Finland
J Intellect Disabil Res 42:63-7. 1998..The role of tiagabine in the management of partial epilepsy of patients with intellectual disability is especially emphasized since tiagabine has a low side-effect profile in the cognitive area...
A woman with seven monotherapiesReetta Kalviainen
Department of Neurology, Kuopio University Hospital, POB 1777, 70211 Kuopio, Finland
Epilepsy Behav 4:S8-11. 2003
Comparison of the cognitive effects of tiagabine and carbamazepine as monotherapy in newly diagnosed adult patients with partial epilepsy: pooled analysis of two long-term, randomized, follow-up studiesMarja Äikiä
Kuopio Epilepsy Center, Kuopio, Finland
Epilepsia 47:1121-7. 2006..Tiagabine (TGB) is indicated as adjunctive therapy for the treatment of partial seizures. The cognitive effects of TGB and carbamazepine (CBZ) monotherapy were evaluated in adult epilepsy patients with partial seizures...
Long-term effects of tiagabine monotherapy on cognition and mood in adult patients with chronic partial epilepsyMarja Äikiä
Kuopio Epilepsy Center, Department of Neurology, Kuopio University Hospital, Kuopio, Finland
Epilepsy Behav 8:750-5. 2006..The results of this small open-label extension study indicate that patients with chronic partial epilepsy who were successfully converted to long-term tiagabine monotherapy demonstrated no adverse effects on cognitive function or mood...
Motor cortical plasticity is impaired in Unverricht-Lundborg diseaseNils Danner
Department of Clinical Neurophysiology, Kuopio University Hospital, Kuopio, Finland
Mov Disord 26:2095-100. 2011..The impaired cortical plasticity may be associated with the previously reported structural and physiological abnormalities of the primary motor cortex...
Non-invasive preoperative localization of primary motor cortex in epilepsy surgery by navigated transcranial magnetic stimulationLaura Säisänen
Department of Clinical Neurophysiology, Kuopio University Hospital, Kuopio, Finland
Epilepsy Res 92:134-44. 2010..Navigated transcranial magnetic stimulation (nTMS) is a non-invasive method to localize the primary motor cortex (M1)...
Increased expression of caspase 2 in experimental and human temporal lobe epilepsySusanna Narkilahti
A I Virtanen Institute for Molecular Sciences, University of Kuopio, and Department of Neurology, Kuopio University Hospital, Finland
Neuromolecular Med 9:129-44. 2007..Our data suggest that caspase 2-mediated programmed cell death participates in the seizure-induced degenerative process in experimental and human TLE...
Severer phenotype in Unverricht-Lundborg disease (EPM1) patients compound heterozygous for the dodecamer repeat expansion and the c.202C>T mutation in the CSTB genePäivi Koskenkorva
Department of Clinical Radiology, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland
Neurodegener Dis 8:515-22. 2011..We describe the clinical, cognitive and imaging characteristics of 5 Finnish EPM1 patients who are compound heterozygous for the dodecamer repeat expansion and the c.202C>T mutations...
The effects of valproate exposure in utero on behavior and the need for educational support in school-aged childrenKatriina Viinikainen
Kuopio Epilepsy Center, Department of Neurology, Kuopio University Hospital and University of Kuopio, POB 1777, 70211, Kuopio, Finland
Epilepsy Behav 9:636-40. 2006..Larger studies with a prospective design are needed to confirm these findings...
Long-term epilepsy surgery outcomes in patients with MRI-negative temporal lobe epilepsyArto Immonen
Department of Neurosurgery, Kuopio University Hospital, Kuopio, Finland
Epilepsia 51:2260-9. 2010..The purpose of this study was to determine the long-term outcomes of consecutive true MRI-negative TLE patients who all underwent standardized preoperative evaluation with intracranial electroencephalography (EEG) electrodes...
Primary motor cortex alterations in a compound heterozygous form of Unverricht-Lundborg disease (EPM1)Nils Danner
Department of Clinical Neurophysiology, Institute of Clinical Medicine, School of Medicine, University of Eastern Finland and Kuopio University Hospital, POB 1777, FIN 70211 Kuopio, Finland
Seizure 20:65-71. 2011..202C>T mutation in the CSTB gene (chEPM1). There are no previous clinical or neurophysiological studies on these patients. Thus, we aimed to characterize possible functional alterations in primary motor cortical areas...
Can BIS monitoring be used to assess the depth of propofol anesthesia in the treatment of refractory status epilepticus?Tadeusz Musialowicz
Department of Anesthesiology and Intensive Care Medicine, Kuopio University Hospital, Kuopio, Finland
Epilepsia 51:1580-6. 2010..We conducted a study to evaluate the feasibility of using the BIS monitoring to assess the burst suppression (BS) pattern during propofol anesthesia in RSE...
Color vision and contrast sensitivity in epilepsy patients treated with initial tiagabine monotherapyIiris Sorri
Department of Ophthalmology, Kuopio University Hospital, P O Box 1777, FIN 70211 Kuopio, Finland Department of Ophthalmology, University of Kuopio, Kuopio, Finland
Epilepsy Res 67:101-7. 2005..Contrast sensitivity function was within normal ranges. The present study suggests that AED therapy with tiagabine, like with other established and newer AEDs may interfere with color perception...
Altered cortical inhibition in Unverricht-Lundborg type progressive myoclonus epilepsy (EPM1)Nils Danner
Department of Clinical Neurophysiology, Kuopio University Hospital and University of Kuopio, POB 1777, Kuopio FI 70211, Finland
Epilepsy Res 85:81-8. 2009..The aim of this study was to assess the function of the motor cortex in Unverricht-Lundborg disease (ULD), progressive myoclonus epilepsy type 1 (EPM1)...
Propofol and barbiturates for the anesthesia of refractory convulsive status epilepticus: pros and consIlkka Parviainen
Department of Anesthesiology and Intensive Care, Kuopio Epilepsy Center, Kuopio University Hospital, Kuopio, Finland
Neurol Res 29:667-71. 2007..To discuss mainly the use of propofol and barbiturates in the anesthesia of refractory status epilepticus (RSE)...
Late-onset Rasmussen's encephalitis and long-term remissionLaura Kupila
Department of Neurology, Paijat Hame Central Hospital, LahtiDepartment of Neurology, Paijat Hame Central Hospital, Lahti, Finland
Epileptic Disord 13:88-91. 2011..To our knowledge, this is the first report of a patient with Rasmussen's encephalitis who has become completely symptomless, at least for three years, on enhanced antiepileptic and immunological medication...
Ophthalmologic and neurologic findings in two children exposed to vigabatrin in uteroIiris Sorri
Department of Ophthalmology, Kuopio University Hospital, P O Box 1777, FIN 70211 Kupio, Finland
Epilepsy Res 65:117-20. 2005..We explored ophthalmic and neurologic findings in two children who have been exposed prenatally to VGB...
Thickened skull, scoliosis and other skeletal findings in Unverricht-Lundborg disease link cystatin B function to bone metabolismSanna Suoranta
Department of Clinical Radiology, Kuopio University Hospital, Kuopio, Finland
Bone 51:1016-24. 2012..Cystatin B, cathepsin K, and altered osteoclast bone resorption activity are interconnected in vitro. This study evaluated the skeletal characteristics of patients with EPM1...
The effect of fMRI task combinations on determining the hemispheric dominance of language functionsEini Niskanen
Department of Applied Physics, University of Eastern Finland, Kuopio, Finland
Neuroradiology 54:393-405. 2012....
Is reduced ornithine-δ-aminotransferase activity the cause of vigabatrin-associated visual field defects?Iiris Sorri
Department of Ophthalmology, Kuopio University Hospital, P O Box 1777, FIN 70211 Kuopio, Finland
Epilepsy Res 92:48-53. 2010..Although the clinical and electrophysiological features of VFDs are well documented, the mechanism of retinal toxicity is still unclear...
Propofol in the treatment of refractory status epilepticusIlkka Parviainen
Department of Anesthesiology and Intensive Care, Kuopio University Hospital, Kuopio, Finland
Intensive Care Med 32:1075-9. 2006..To study prospectively the effects of propofol anesthesia on seizure control, hemodynamics and course of intensive care in patients with refractory status epilepticus...
More severe epilepsy and cognitive impairment in the offspring of a mother with mosaicism for the ring 20 chromosomeEila Herrgard
Kuopio Epilepsy Center, FIN 70211 Kuopio, Finland
Epilepsy Res 73:122-8. 2007..Cases tend to be sporadic. We elucidate the characteristics of an inherited r(20) mosaicism by describing the clinical features of three family members: a mother and her two children...
Visual function in epilepsy patients treated with initial valproate monotherapyIiris Sorri
Department of Ophthalmology, Kuopio University Hospital, FIN 70211 Kuopio, Finland
Seizure 14:367-70. 2005..To investigate whether initial valproate (VPA) monotherapy for the treatment of epilepsy causes visual field defects and visual dysfunction...
Cystatin C expression is associated with granule cell dispersion in epilepsyTerhi J Pirttilä
A I Virtanen Institute for Molecular Sciences, University of Kuopio, Kuopio, Finland
Ann Neurol 58:211-23. 2005....
Infertility treatment and umbilical cord length-novel markers of childhood epilepsy?Sari Räisänen
Department of Obstetrics and Gynaecology, Kuopio University Hospital, Kuopio, Finland
PLoS ONE 8:e55394. 2013..Epilepsy is one of the most common neurologic disorders of childhood, affecting about 0.4-0.8% of all children up to the age of 20...
