E Jantunen

Summary

Affiliation: Kuopio University Hospital
Country: Finland

Publications

  1. pmc Oxidative stress and redox state-regulating enzymes have prognostic relevance in diffuse large B-cell lymphoma
    Pekka Peroja
    Department of Oncology and Radiotherapy, University of Oulu and Oulu University Hospital, Oulu, Finland
    Exp Hematol Oncol 1:2. 2012
  2. doi request reprint Autologous stem cell transplantation for enteropathy-associated T-cell lymphoma: a retrospective study by the EBMT
    Esa Jantunen
    University of Eastern Finland Clinical Medicine and Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Blood 121:2529-32. 2013
  3. doi request reprint Kinetics of blood CD34(+) cells after chemotherapy plus G-CSF in poor mobilizers: implications for pre-emptive plerixafor use
    E Jantunen
    University of Eastern Finland Clinical Medicine, Kuopio, Finland
    Ann Hematol 91:1073-9. 2012
  4. doi request reprint The evolving role of stem cell transplants in lymphomas
    Esa Jantunen
    Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland
    Biol Blood Marrow Transplant 18:660-73. 2012
  5. doi request reprint Preemptive use of plerixafor in difficult-to-mobilize patients: an emerging concept
    Esa Jantunen
    University of Eastern Finland Clinical Medicine and Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Transfusion 52:906-14. 2012
  6. doi request reprint Autologous stem cell transplantation in elderly patients (> or =60 years) with diffuse large B-cell lymphoma: an analysis based on data in the European Blood and Marrow Transplantation registry
    Esa Jantunen
    Department of Medicine, Kuopio University Hospital, POB 1777, 70211 Kuopio, Finland
    Haematologica 93:1837-42. 2008
  7. ncbi request reprint Stem cell transplantation in autoimmune diseases: an update
    Esa Jantunen
    Department of Medicine, Kuopio University Hospital, P O B 1777, 70211 Kuopio, Finland
    Ann Med 37:533-41. 2005
  8. ncbi request reprint Early treatment-related mortality in adult autologous stem cell transplant recipients: a nation-wide survey of 1482 transplanted patients
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Eur J Haematol 76:245-50. 2006
  9. ncbi request reprint Autologous stem cell transplantation in elderly (>60 years) patients with non-Hodgkin's lymphoma: a nation-wide analysis
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Bone Marrow Transplant 37:367-72. 2006
  10. ncbi request reprint Autologous stem cell transplantation in patients with high-risk plasmacytoma
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Eur J Haematol 74:402-6. 2005

Detail Information

Publications68

  1. pmc Oxidative stress and redox state-regulating enzymes have prognostic relevance in diffuse large B-cell lymphoma
    Pekka Peroja
    Department of Oncology and Radiotherapy, University of Oulu and Oulu University Hospital, Oulu, Finland
    Exp Hematol Oncol 1:2. 2012
    ..abstract:..
  2. doi request reprint Autologous stem cell transplantation for enteropathy-associated T-cell lymphoma: a retrospective study by the EBMT
    Esa Jantunen
    University of Eastern Finland Clinical Medicine and Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Blood 121:2529-32. 2013
    ..062). ASCT is feasible in selected patients with EATL and can yield durable disease control in a significant proportion of the patients...
  3. doi request reprint Kinetics of blood CD34(+) cells after chemotherapy plus G-CSF in poor mobilizers: implications for pre-emptive plerixafor use
    E Jantunen
    University of Eastern Finland Clinical Medicine, Kuopio, Finland
    Ann Hematol 91:1073-9. 2012
    ..97 and specificity 1.00, respectively, to identify patients for plerixafor use provided that all patients with B-CD34+ maximum ≤10×10(6)/l would have needed plerixafor.This simple model needs a prospective validation...
  4. doi request reprint The evolving role of stem cell transplants in lymphomas
    Esa Jantunen
    Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland
    Biol Blood Marrow Transplant 18:660-73. 2012
    ..Prospective, randomized studies are needed to evaluate feasibility and efficacy of alloSCT in several clinical settings, as most published evidence is based on retrospective registry data or single-center experiences...
  5. doi request reprint Preemptive use of plerixafor in difficult-to-mobilize patients: an emerging concept
    Esa Jantunen
    University of Eastern Finland Clinical Medicine and Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Transfusion 52:906-14. 2012
    ....
  6. doi request reprint Autologous stem cell transplantation in elderly patients (> or =60 years) with diffuse large B-cell lymphoma: an analysis based on data in the European Blood and Marrow Transplantation registry
    Esa Jantunen
    Department of Medicine, Kuopio University Hospital, POB 1777, 70211 Kuopio, Finland
    Haematologica 93:1837-42. 2008
    ..There is currently limited experience on the feasibility and efficacy of autologous stem cell transplantation in elderly patients with diffuse large B-cell lymphoma...
  7. ncbi request reprint Stem cell transplantation in autoimmune diseases: an update
    Esa Jantunen
    Department of Medicine, Kuopio University Hospital, P O B 1777, 70211 Kuopio, Finland
    Ann Med 37:533-41. 2005
    ..Since autologous SCT may not be curative in patients with AID, also evaluation of allogeneic SCT is important in the future...
  8. ncbi request reprint Early treatment-related mortality in adult autologous stem cell transplant recipients: a nation-wide survey of 1482 transplanted patients
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Eur J Haematol 76:245-50. 2006
    ..To evaluate early (<100 d) treatment-related mortality (TRM) in autologous stem cell transplant (ASCT) recipients...
  9. ncbi request reprint Autologous stem cell transplantation in elderly (>60 years) patients with non-Hodgkin's lymphoma: a nation-wide analysis
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Bone Marrow Transplant 37:367-72. 2006
    ..A relapse or progression after ASCT has been observed in 32 patients (36%). ASCT is feasible in selected elderly patients with NHL, but the early TRM seems to be higher than in younger patients...
  10. ncbi request reprint Autologous stem cell transplantation in patients with high-risk plasmacytoma
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Eur J Haematol 74:402-6. 2005
    ..ASCT is feasible in this patient population resulting in promising overall survival. A randomised trial is needed to assess the real value of ASCT when compared with other treatment options in patients with high-risk PC...
  11. ncbi request reprint [Primary bone lymphomas. Experiences in Kuopio University Central Hospital during 1990-2003]
    Esa Jantunen
    KYS n sisätautien klinikka, Kuopio
    Duodecim 120:2681-7. 2004
  12. ncbi request reprint Autologous stem cell transplantation in patients with primary amyloidosis: a nation-wide survey
    E Jantunen
    Department of Medicine Kuopio University Hospital Kuopio Finland
    Leuk Lymphoma 45:2485-9. 2004
    ..A randomized multicentre trial is needed to show whether ASCT is superior to conventional therapy in patients with AL...
  13. ncbi request reprint Candidaemia in allogeneic stem cell transplant recipients: low risk without fluconazole prophylaxis
    E Jantunen
    Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Bone Marrow Transplant 34:891-5. 2004
    ..Thus, systematic prophylaxis against Candida infections might not be indicated. The prognosis of established infections is still poor due to comorbid conditions, notably GVHD...
  14. ncbi request reprint Autologous stem cell transplantation beyond 60 years of age
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Bone Marrow Transplant 38:715-20. 2006
    ..Also, further studies are needed in order to decrease toxicity of high-dose regimens in this patient group where co-morbid conditions may modify the toxicity of HDT in a clinically significant manner...
  15. ncbi request reprint [The use of anagrelide to treat thrombocytosis in connection with the chronic myeloproliferative disease]
    Esa Jantunen
    KYS n sisätautien klinikka, Kuopio
    Duodecim 122:453-7. 2006
  16. ncbi request reprint High-dose melphalan (200 mg/m2) supported by autologous stem cell transplantation is safe and effective in elderly (>or=65 years) myeloma patients: comparison with younger patients treated on the same protocol
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Bone Marrow Transplant 37:917-22. 2006
    ..We conclude that MEL200 is a safe and efficacious treatment in selected elderly myeloma patients...
  17. doi request reprint Novel strategies for blood stem cell mobilization: special focus on plerixafor
    Esa Jantunen
    University of Eastern Finland, and Kuopio University Hospital, Department of Medicine, POB 1777, 70211 Kuopio, Finland
    Expert Opin Biol Ther 11:1241-8. 2011
    ..Blood stem cell mobilization strategies are therefore important components of all transplant programs...
  18. doi request reprint Efficacy of pre-emptively used plerixafor in patients mobilizing poorly after chemomobilization: a single centre experience
    Esa Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland University of Eastern Finland Institute of Clinical Medicine, Kuopio, Finland
    Eur J Haematol 86:299-304. 2011
    ..In patients with low but rising B-CD34(+) counts, the use of plerixafor might be delayed as late mobilization may occur. Further studies are needed to optimize patient selection and timing of plerixafor...
  19. doi request reprint Mobilization strategies in hard-to-mobilize patients with lymphoid malignancies
    Esa Jantunen
    University of Eastern Finland Institute of Clinical Medicine, Kuopio, Finland
    Eur J Haematol 85:463-71. 2010
    ..This review attempts to summarize current treatment strategies in hard-to-mobilize patients with lymphoid malignancies...
  20. doi request reprint Changing landscape of invasive aspergillosis in allogeneic stem cell transplant recipients
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Transpl Infect Dis 10:156-61. 2008
    ..Despite some promises and improvements, IA will continue to remain a challenge in the upcoming years...
  21. doi request reprint Blood stem cell mobilization and collection in patients with lymphoproliferative diseases: practical issues
    Esa Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Eur J Haematol 80:287-95. 2008
    ..There seems to be even more disease-specific issues in blood stem cell mobilization in patients with chronic lymphocytic leukaemia and in patients with light chain amyloidosis. We also discuss options in hard-to-mobilize patients...
  22. ncbi request reprint Blood stem cell mobilization and collection in patients with chronic lymphocytic leukaemia: a nationwide analysis
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Bone Marrow Transplant 41:239-44. 2008
    ..001). A significant proportion of patients with CLL were difficult to mobilize. Adequate marrow function including platelet counts >100 x 10(9)/l seem to be important factors in terms of successful blood stem cell collection...
  23. ncbi request reprint Late non-relapse mortality among adult autologous stem cell transplant recipients: a nation-wide analysis of 1,482 patients transplanted in 1990-2003
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Eur J Haematol 77:114-9. 2006
    ..Altogether 22 patients (32% of late NRM) died from infectious causes. Malignancies and late infections are important causes of NRM after ASCT. These facts point out the importance of prolonged follow-up in ASCT recipients...
  24. ncbi request reprint Autologous stem cell transplantation in patients with chronic lymphocytic leukaemia: the Finnish experience
    E Jantunen
    Department of Medicine, Kuopio University Hospital, 70211 Kuopio, Finland
    Bone Marrow Transplant 37:1093-8. 2006
    ..Autologous stem cell transplantation is a feasible treatment option for CLL. Randomized trials against alternative treatments are needed to assess the impact of ASCT on the clinical course of CLL...
  25. ncbi request reprint Invasive fungal infections in autologous stem cell transplant recipients: a nation-wide study of 1188 transplanted patients
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Finland
    Eur J Haematol 73:174-8. 2004
    ..Based on small single-centre series, the risk of invasive fungal infections (IFI) has been considered small in autologous stem cell transplant (ASCT) recipients...
  26. ncbi request reprint Stem cell transplantation for peripheral T-cell lymphomas
    Esa Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Leuk Lymphoma 45:441-6. 2004
    ..lymphoma effect, also this approach should be studied. Due to rarity of PTCL, international collaboration is mandatory in order to study the various aspects of SCT in this patient population...
  27. ncbi request reprint Bisphosphonate therapy in multiple myeloma: past, present, future
    Esa Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Eur J Haematol 69:257-64. 2002
    ..Bisphosphonate therapy is now accepted as an important part of care in myeloma patients, although much still has to be learned in order to optimise this therapy in multiple myeloma...
  28. ncbi request reprint Multiple complete remissions in a patient with acute myeloid leukemia (M4eo) with low-dose cytosine arabinoside and all-trans retinoic acid
    E Jantunen
    Department of Medicine, Kuopio University Hospital, P O B 1777, 70211 Kuopio, Finland
    Leuk Lymphoma 44:883-5. 2003
    ..The patient survived 81 months after the start with LDAraC-ATRA regimen. This low-toxicity regimen may be useful in some patients with poor-risk AML...
  29. ncbi request reprint A pilot study on feasibility and efficacy of amifostine preceding high-dose melphalan with autologous stem cell support in myeloma patients
    E Jantunen
    Department of Medicine, Kuopio University Hospital, P O Box 1777, 70211 Kuopio, Finland
    Leuk Lymphoma 43:1961-5. 2002
    ..Whether AMI could reduce the gastrointestinal toxicity associated with high-dose MEL can be reliably assessed only in prospective randomized trials...
  30. ncbi request reprint BEAC or BEAM for high-dose therapy in patients with non-Hodgkin's lymphoma? A single centre analysis on toxicity and efficacy
    E Jantunen
    Department of Medicine, Kuopio University Hospital, PO Box 1777, 70211 Kuopio, Finland
    Leuk Lymphoma 44:1151-8. 2003
    ..However, randomised studies are needed for more definitive conclusions on the relative merits of various high-dose regimens in patients with NHL...
  31. ncbi request reprint Is chemotherapy scoring useful to predict progenitor cell mobilisation in patients with non-Hodgkin's lymphoma?
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Bone Marrow Transplant 32:569-73. 2003
    ..Thus, both the original scoring system as well as our more widely applicable scoring system seem to be of limited value in predicting progenitor cell mobilisation in patients with NHL...
  32. ncbi request reprint Autologous stem cell transplantation in adult patients with peripheral T-cell lymphoma: a nation-wide survey
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Bone Marrow Transplant 33:405-10. 2004
    ..007). OS at 5 years was 63% in patients transplanted in CR/PR1 vs 45% in those transplanted in other disease status (P=NS). Prospective studies are needed to define the role of ASCT in this lymphoma type...
  33. doi request reprint Importance of blood graft characteristics in auto-SCT: implications for optimizing mobilization regimens
    E Jantunen
    University of Eastern Finland Institute of Clinical Medicine and Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Bone Marrow Transplant 46:627-35. 2011
    ..These studies are not only important in regard to defining the optimal stem-cell graft in the autologous setting, but also in identifying the optimal mobilization regimen...
  34. ncbi request reprint Cardiac effects within 3 months of BEAC high-dose therapy in non-Hodgkin's lymphoma patients undergoing autologous stem cell transplantation
    T Kuittinen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Eur J Haematol 77:120-7. 2006
    ..We prospectively assessed the cardiac effects of high-dose CY in 30 adult NHL patients receiving CY 6 g/m(2) as part of BEAC high-dose therapy (HDT)...
  35. ncbi request reprint Neuroendocrine changes during the evolution of doxorubicin-induced left ventricular dysfunction in adult lymphoma patients
    T Nousiainen
    Department of Medicine, Kuopio University Hospital, P O B 1777, 70211 Kuopio, Finland
    Clin Sci (Lond) 101:601-7. 2001
    ..Along with further progression of left ventricular dysfunction, there is an attenuation of sympathetic tone, which may be attributable to sympatho-adrenal inhibition by increased secretion of natriuretic peptides...
  36. ncbi request reprint Very acute cardiac toxicity during BEAC chemotherapy in non-Hodgkin's lymphoma patients undergoing autologous stem cell transplantation
    T Kuittinen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Bone Marrow Transplant 36:1077-82. 2005
    ..This toxicity can be detected with increased concentrations of circulating natriuretic peptides but not with LVEF measurement...
  37. ncbi request reprint Outcome of progressive disease after autologous stem cell transplantation in patients with non-Hodgkin's lymphoma: a nation-wide survey
    T Kuittinen
    Department of Medicine, Kuopio University Hospital, Finland
    Eur J Haematol 75:199-205. 2005
    ..To analyse outcome and prognostic factors in non-Hodgkin's lymphoma (NHL) patients who progress after autologous stem cell transplantation (ASCT)...
  38. ncbi request reprint Comparison of echocardiography and radionuclide ventriculography in the follow-up of left ventricular systolic function in adult lymphoma patients during doxorubicin therapy
    T Nousiainen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    J Intern Med 249:297-303. 2001
    ..To compare echocardiography (ECHO) and radionuclide ventriculography (RVG) in the monitoring of left ventricular systolic function during doxorubicin therapy in adult lymphoma patients...
  39. ncbi request reprint Natriuretic peptides as markers of cardiotoxicity during doxorubicin treatment for non-Hodgkin's lymphoma
    T Nousiainen
    Department of Medicine, Kuopio University Hospital and University of Kuopio, Finland
    Eur J Haematol 62:135-41. 1999
    ..On the other hand, our study suggests that natriuretic peptides are useful in the detection of subclinical left ventricular dysfunction in patients receiving doxorubicin therapy...
  40. ncbi request reprint Acute neurohumoral and cardiovascular effects of idarubicin in leukemia patients
    T Nousiainen
    Department of Medicine, Kuopio University Hospital and University of Kuopio, Finland
    Eur J Haematol 61:347-53. 1998
    ..Whether these acute changes predict late clinical cardiomyopathy should be evaluated in prospective studies with larger number of patients and with higher cumulative anthracycline doses...
  41. ncbi request reprint Aspergillus infections in allogeneic stem cell transplant recipients: have we made any progress?
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Bone Marrow Transplant 30:925-9. 2002
    ..Further studies in this field will focus on the role of various cytokines and combinations of antifungal agents...
  42. doi request reprint Pre-emptive plerixafor injection increases blood neutrophil, lymphocyte and monocyte counts in addition to CD34+ counts in patients with non-Hodgkin lymphoma mobilizing poorly with chemotherapy plus G-CSF: potential implications for apheresis and graft co
    V Varmavuo
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Transfus Apher Sci 46:257-62. 2012
    ..No detailed data regarding the effects of plerixafor on other blood cell components have been published but may be of importance in regard to graft composition collected after plerixafor injection...
  43. ncbi request reprint Prediction of mobilisation failure in patients with non-Hodgkin's lymphoma
    T Kuittinen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Bone Marrow Transplant 33:907-12. 2004
    ..71 and a specificity of 0.77 in the prediction of mobilisation failure. Patients at a high risk of mobilisation failure may benefit from novel approaches...
  44. ncbi request reprint Autologous stem cell transplantation in patients with mantle cell lymphoma
    Riikka Oinonen
    Department of Medicine, Helsinki University Central Hospital, Finland
    Leuk Lymphoma 43:1229-37. 2002
    ..However, no plateau was seen in the EFS curve after ASCT. Whether cure Can be achieved in a proportion of patients with ASCT is currently unknown and should be studied in larger patient series with a longer follow-up...
  45. pmc Early decline in left ventricular ejection fraction predicts doxorubicin cardiotoxicity in lymphoma patients
    T Nousiainen
    Department of Medicine, Kuopio University Hospital and University of Kuopio, FIN 70211 Kuopio, Finland
    Br J Cancer 86:1697-700. 2002
    ..This finding may be of value in identifying patients at high or low risk for the development of anthracycline cardiotoxicity...
  46. ncbi request reprint Central nervous system aspergillosis in allogeneic stem cell transplant recipients
    E Jantunen
    Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Bone Marrow Transplant 31:191-6. 2003
    ..CNS aspergillosis is not uncommon in allogeneic SCT recipients. Clinical manifestations are usually dramatic and progress quickly. Earlier and more effective treatment of IA is needed to prevent dissemination of infection into the CNS...
  47. ncbi request reprint Low-dose or intermediate-dose cyclophosphamide plus granulocyte colony-stimulating factor for progenitor cell mobilisation in patients with multiple myeloma
    E Jantunen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Bone Marrow Transplant 31:347-51. 2003
    ....
  48. doi request reprint Impact of germinal center and non-germinal center phenotypes on overall and failure-free survival after high-dose chemotherapy and auto-SCT in primary diffuse large B-cell lymphoma
    H Nyman
    Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
    Bone Marrow Transplant 42:93-8. 2008
    ..The data imply that auto-SCT can overcome the adverse prognostic impact of the non-GC phenotype in patients with high-risk DLBCL and warrant additional prospective studies...
  49. ncbi request reprint Radiologically guided fine needle lung biopsies in the evaluation of focal pulmonary lesions in allogeneic stem cell transplant recipients
    E Jantunen
    Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Bone Marrow Transplant 29:353-6. 2002
    ..Radiologically guided FNLB is feasible in allogeneic SCT recipients and has a low complication rate. The diagnostic yield is high especially for IPA...
  50. doi request reprint Severe sepsis in autologous stem cell transplant recipients: microbiological aetiology, risk factors and outcome
    Sari Hamalainen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Scand J Infect Dis 41:14-20. 2009
    ..Severe sepsis is an important cause of early mortality after ASCT, especially in NHL patients. Ways to prevent development of severe sepsis or predict its development might reduce early mortality among ASCT recipients...
  51. ncbi request reprint QT dispersion and late potentials during doxorubicin therapy for non-Hodgkin's lymphoma
    T Nousiainen
    Department of Medicine, Kuopio University Hospital, Finland
    J Intern Med 245:359-64. 1999
    ..To investigate effects of doxorubicin therapy on cardiac electrophysiology, with special emphasis on QT dispersion and late potentials, in lymphoma patients...
  52. ncbi request reprint Autologous peripheral blood stem cell transplantation in a patient with severe mixed connective tissue disease
    R Myllykangas-Luosujärvi
    Department of Medicine, Kuopio University Hospital, Finland
    Scand J Rheumatol 29:326-7. 2000
    ..Based on histopathological examination there is still active myositis. Our case would suggests that this treatment may have some efficacy in MCTD with severe polymyositis although longer follow-up is needed...
  53. doi request reprint Serum amino-terminal pro-brain natriuretic peptide in hematological patients with neutropenic fever: a prospective comparison with C-reactive protein
    Sari Hamalainen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Leuk Lymphoma 51:1040-6. 2010
    ..NT-proBNP seemed to reflect cardiac distress, but it did not help to predict the development of severe sepsis in this patient group...
  54. doi request reprint Serum vascular endothelial growth factor in adult haematological patients with neutropenic fever: a comparison with C-reactive protein
    Sari Hamalainen
    Department of Medicine, Kuopio University Hospital, P O B 1777, Kuopio 70211, Finland
    Eur J Haematol 83:251-7. 2009
    ..Vascular endothelial growth factor (VEGF) is considered to be of importance in patients with sepsis. No data are available on VEGF kinetics in haematological patients with neutropenic fever...
  55. doi request reprint Serial plasma lactate measurements in haematological patients with neutropenic fever
    Auni Juutilainen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Scand J Infect Dis 42:102-8. 2010
    ..An elevated plasma lactate level at the start of neutropenic fever is not common and does not indicate severe sepsis, but high lactate and an impaired lactate decrease may signify a fatal course in neutropenic fever...
  56. doi request reprint Neutropenic fever and severe sepsis in adult acute myeloid leukemia (AML) patients receiving intensive chemotherapy: Causes and consequences
    Sari Hamalainen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Leuk Lymphoma 49:495-501. 2008
    ..Severe sepsis is associated with significant mortality in AML patients. Earlier methods than CRP are needed to predict development of severe sepsis...
  57. ncbi request reprint Concomitant impairment of left ventricular systolic and diastolic function during doxorubicin therapy: a prospective radionuclide ventriculographic and echocardiographic study
    Tapio Nousiainen
    Department of Medicine, Kuopio University Hospital, P O B 1777, 70211 Kuopio, Finland
    Leuk Lymphoma 43:1807-11. 2002
    ..In addition, these changes manifest at relatively low cumulative doxorubicin doses and occur concomitantly. Thus, the assessment of diastolic function provides no advantage over monitoring systolic function during doxorubicin therapy...
  58. ncbi request reprint Bisphosphonate therapy in multiple myeloma
    M Laakso
    Department of Medicine, University of Kuopio, Finland
    Acta Oncol 35:55-6. 1996
    ..Bisphosphonates are a useful adjunct therapy in patients with multiple myeloma...
  59. doi request reprint Prognostic impact of CD31-positive microvessel density in follicular lymphoma patients treated with immunochemotherapy
    Minna Taskinen
    Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
    Eur J Cancer 46:2506-12. 2010
    ..Here we investigated whether tumour vascularity is associated with MC content and outcome in FL patients treated with immunochemotherapy...
  60. doi request reprint Acute lymphoblastic leukemia in adolescents and young adults in Finland
    Anu Usvasalo
    Hospital for Children and Adolescents, University of Helsinki, P O Box 281, 00029 HUS, Helsinki, Finland
    Haematologica 93:1161-8. 2008
    ..We, therefore, studied acute lymphoblastic leukemia in adolescents and young adults aged 10 to 25 years in Finland...
  61. doi request reprint Autologous stem-cell transplantation in patients with mantle cell lymphoma beyond 65 years of age: a study from the European Group for Blood and Marrow Transplantation (EBMT)
    E Jantunen
    Department of Medicine, Institute of Clinical Medicine, University of Eastern Finland and Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    Ann Oncol 23:166-71. 2012
    ..Limited experience is available on the feasibility and efficacy of autologous stem-cell transplantation (ASCT) in patients with mantle cell lymphoma (MCL) beyond 65 years...
  62. ncbi request reprint Natriuretic peptides during the development of doxorubicin-induced left ventricular diastolic dysfunction
    T Nousiainen
    Department of Medicine, Kuopio University Hospital, Kuopio, Finland
    J Intern Med 251:228-34. 2002
    ....
  63. doi request reprint Late potentials and QT dispersion after high-dose chemotherapy in patients with non-Hodgkin lymphoma
    Taru Kuittinen
    Hematology Research Unit, Helsinki University Central Hospital and University of Helsinki, Helsinki, Helsinki, Finland
    Clin Physiol Funct Imaging 30:175-80. 2010
    ..Thus, longer follow-up is required to confirm the meaning of these adverse effects on cardiac function and quality of life...
  64. ncbi request reprint Long-term outcome of intensive chemotherapy for adults with de novo acute myeloid leukaemia (AML): the nationwide AML-92 study by the Finnish Leukaemia Group
    Pirjo Koistinen
    Department of Medicine, Oulu University Hospital, Oulu, Finland
    Eur J Haematol 78:477-86. 2007
    ..To investigate the long-term outcome of idarubicin- and cytarabine-based intensive chemotherapy in adult acute myeloid leukaemia (AML)...
  65. ncbi request reprint [Lymphomas of the gastrointestinal tract]
    Martine Vornanen
    TAYS n laboratoriokeskus, patologian vastuualue, Tampere
    Duodecim 120:1859-65. 2004
  66. pmc Haematopoietic stem cell transplantation for vasculitis including Behcet's disease and polychondritis: a retrospective analysis of patients recorded in the European Bone Marrow Transplantation and European League Against Rheumatism databases and a review
    Thomas Daikeler
    Department of Rheumatology, University of Basle, Petersgraben 4, CH 4031 Basle, Switzerland
    Ann Rheum Dis 66:202-7. 2007
    ..To evaluate the feasibility of haematopoietic stem cell transplantation (HSCT) in vasculitis...
  67. ncbi request reprint Autologous hemopoietic stem cell transplantation in severe rheumatoid arthritis: a report from the EBMT and ABMTR
    John A Snowden
    Department of Rheumatology, Felix Platter Spital, University of Basel, Basel, Switzerland
    J Rheumatol 31:482-8. 2004
    ..To date, published reports have been individual cases or series containing small numbers. This study combined the worldwide experience in a single analysis...
  68. ncbi request reprint [Large granular lymphocytic leukemia]
    Esa Jantunen
    KYS n sisätautien Klinikka PL 1777, 70211 Kuopio
    Duodecim 118:177-81. 2002