T Hanninen

Summary

Affiliation: Kuopio University Hospital
Country: Finland

Publications

  1. pmc Cognitive and Neuropsychiatric Symptom Differences in Early Stages of Alzheimer's Disease: Kuopio ALSOVA Study
    Ilona Hallikainen
    Institute of Clinical Medicine, Neurology, University of Eastern Finland, Mikkeli, Finland
    Dement Geriatr Cogn Dis Extra 2:209-18. 2012
  2. ncbi request reprint Age-associated memory impairment. Normal aging or warning of dementia?
    T Hanninen
    Department of Neurology, Kuopio University Hospital, Finland
    Drugs Aging 11:480-9. 1997
  3. ncbi request reprint Prevalence of mild cognitive impairment: a population-based study in elderly subjects
    T Hanninen
    Department of Neuroscience and Neurology, University of Kuopio, Finland
    Acta Neurol Scand 106:148-54. 2002
  4. pmc A voxel based morphometry study on mild cognitive impairment
    C Pennanen
    Department of Neurology, Bldg 5, Kuopio University Hospital, POB 1777, 70211 Kuopio, Finland
    J Neurol Neurosurg Psychiatry 76:11-4. 2005
  5. ncbi request reprint Midlife vascular risk factors and late-life mild cognitive impairment: A population-based study
    M Kivipelto
    Department of Neuroscience and Neurology, University of Kuopio, Finland
    Neurology 56:1683-9. 2001
  6. ncbi request reprint Cognitive function in an elderly population with persistent impaired glucose tolerance
    M Vanhanen
    Department of Neurology, Kuopio University Hospital, Finland
    Diabetes Care 21:398-402. 1998
  7. pmc Fragile-X: neuropsychological test performance, CGG triplet repeat lengths, and hippocampal volumes
    P Jakala
    Department of Neuroscience and Neurology, University Hospital and University of Kuopio, Finland
    J Clin Invest 100:331-8. 1997
  8. pmc Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study
    M Kivipelto
    Department of Neuroscience and Neurology, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
    BMJ 322:1447-51. 2001
  9. ncbi request reprint Diagnosis of Alzheimer's disease: MRI of the hippocampus vs delayed recall
    M P Laakso
    Department of Neurology, Kuopio University Hospital, Kuopio, Finland
    Neuropsychologia 38:579-84. 2000
  10. pmc Plasma Abeta42 and Abeta40 as markers of cognitive change in follow-up: a prospective, longitudinal, population-based cohort study
    T T Seppälä
    Department of Neurology, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland
    J Neurol Neurosurg Psychiatry 81:1123-7. 2010

Collaborators

Detail Information

Publications19

  1. pmc Cognitive and Neuropsychiatric Symptom Differences in Early Stages of Alzheimer's Disease: Kuopio ALSOVA Study
    Ilona Hallikainen
    Institute of Clinical Medicine, Neurology, University of Eastern Finland, Mikkeli, Finland
    Dement Geriatr Cogn Dis Extra 2:209-18. 2012
    ..The aim of this study was to examine whether demographic variables, dementia severity, ADL and neuropsychiatric symptoms are associated with cognition in very mild or mild AD...
  2. ncbi request reprint Age-associated memory impairment. Normal aging or warning of dementia?
    T Hanninen
    Department of Neurology, Kuopio University Hospital, Finland
    Drugs Aging 11:480-9. 1997
    ..More reliable diagnostic approaches are needed for use in studies that are attempting to identify the risk factors for dementia or to find a treatment for very early dementia...
  3. ncbi request reprint Prevalence of mild cognitive impairment: a population-based study in elderly subjects
    T Hanninen
    Department of Neuroscience and Neurology, University of Kuopio, Finland
    Acta Neurol Scand 106:148-54. 2002
    ..In follow-up studies, more than 50% of MCI subjects have been converted to dementia in 3-4 years. However, the epidemiology of MCI is not well known. This study was designed to determine the prevalence of MCI in an elderly population...
  4. pmc A voxel based morphometry study on mild cognitive impairment
    C Pennanen
    Department of Neurology, Bldg 5, Kuopio University Hospital, POB 1777, 70211 Kuopio, Finland
    J Neurol Neurosurg Psychiatry 76:11-4. 2005
    ..A number of volumetric magnetic resonance imaging (MRI) studies have detected atrophy of the medial temporal lobe in subjects with MCI, but for the other cerebral regions the results have been inconsistent...
  5. ncbi request reprint Midlife vascular risk factors and late-life mild cognitive impairment: A population-based study
    M Kivipelto
    Department of Neuroscience and Neurology, University of Kuopio, Finland
    Neurology 56:1683-9. 2001
    ....
  6. ncbi request reprint Cognitive function in an elderly population with persistent impaired glucose tolerance
    M Vanhanen
    Department of Neurology, Kuopio University Hospital, Finland
    Diabetes Care 21:398-402. 1998
    ..To study cognitive function in an elderly population with persistent impaired glucose tolerance (IGT)...
  7. pmc Fragile-X: neuropsychological test performance, CGG triplet repeat lengths, and hippocampal volumes
    P Jakala
    Department of Neuroscience and Neurology, University Hospital and University of Kuopio, Finland
    J Clin Invest 100:331-8. 1997
    ..The data suggest minor abnormalities in temporal lobe structures in adult fra(X) subjects with fM...
  8. pmc Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study
    M Kivipelto
    Department of Neuroscience and Neurology, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
    BMJ 322:1447-51. 2001
    ..To examine the relation of midlife raised blood pressure and serum cholesterol concentrations to Alzheimer's disease in later life...
  9. ncbi request reprint Diagnosis of Alzheimer's disease: MRI of the hippocampus vs delayed recall
    M P Laakso
    Department of Neurology, Kuopio University Hospital, Kuopio, Finland
    Neuropsychologia 38:579-84. 2000
    ..93 for the left hippocampus and 0.96 for the VRT. These data suggest that assessment of delayed recall with the VRT is of high diagnostic accuracy, and may surpass the diagnostic accuracy of hippocampal volumetry...
  10. pmc Plasma Abeta42 and Abeta40 as markers of cognitive change in follow-up: a prospective, longitudinal, population-based cohort study
    T T Seppälä
    Department of Neurology, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland
    J Neurol Neurosurg Psychiatry 81:1123-7. 2010
    ..However, changes in plasma Aβ levels during repeated testing may be helpful in the prediction and evaluation of progression of the incipient AD or mild cognitive impairment...
  11. doi request reprint Heterogeneity of cerebral perfusion 1 week after haemorrhage is an independent predictor of clinical outcome in patients with aneurysmal subarachnoid haemorrhage
    T Mustonen
    Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland
    J Neurol Neurosurg Psychiatry 79:1128-33. 2008
    ....
  12. doi request reprint Apolipoprotein E epsilon 4 allele is associated with increased atrophy in progressive mild cognitive impairment: a voxel-based morphometric study
    A Hämäläinen
    Department of Neuroscience and Neurology, University of Kuopio and Brain Research Unit, Clinical Research Center, Mediteknia, Kuopio, Finland
    Neurodegener Dis 5:186-9. 2008
    ..The apolipoprotein E (APOE) epsilon4 allele is a risk factor for Alzheimer's disease. Earlier studies have shown differences in brain structure according to the APOE epsilon4 status...
  13. ncbi request reprint APOE-epsilon4 is associated with weight loss in women with AD: a population-based study
    M Vanhanen
    Department of Neurology of the Kuopio University Hospital, Finland
    Neurology 56:655-9. 2001
    ..To investigate whether the APOE-epsilon4 allele is associated with weight loss in patients with AD or in nondemented elderly subjects...
  14. doi request reprint Atrophic enlargement of CSF volume after subarachnoid hemorrhage: correlation with neuropsychological outcome
    P Bendel
    Department of Clinical Radiology, Kuopio University Hospital and University of Kuopio, Finland
    AJNR Am J Neuroradiol 31:370-6. 2010
    ..Our aim was to quantify the late ventricular dilation and volumes of the CSF spaces after aSAH and to determine if they correlate with neurologic and cognitive impairments frequently detected in these patients...
  15. ncbi request reprint Subarachnoid hemorrhage is followed by temporomesial volume loss: MRI volumetric study
    P Bendel
    Department of Clinical Radiology, Kuopio University Hospital, Kuopio University, Kuopio, Finland
    Neurology 67:575-82. 2006
    ..To assess whether subarachnoid hemorrhage (SAH) and its treatment is followed by volume loss in temporomesial structures...
  16. doi request reprint CERAD-neuropsychological battery in screening mild Alzheimer's disease
    M Sotaniemi
    Department of Psychology, Institute of Behavioural Sciences, University of Helsinki, Finland
    Acta Neurol Scand 125:16-23. 2012
    ..However, some of its parts need reassessment and focusing. The goal of this study was to examine the sensitivity and specificity of the subtests and their cut-off points most appropriate for identifying mild Alzheimer's disease (AD)...
  17. doi request reprint Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: a longitudinal study
    B Hooshmand
    Aging Research Center, KarolinskaInstitutet, Stockholm, Sweden
    J Intern Med 271:204-12. 2012
    ....
  18. ncbi request reprint Polymorphisms in the CYP19 gene confer increased risk for Alzheimer disease
    S Iivonen
    Department of Neuroscience and Neurology, University Hospital and University of Kuopio, Finland
    Neurology 62:1170-6. 2004
    ..Aromatase is encoded by the CYP19 gene located at 15q21.1, a chromosomal region in linkage disequilibrium (LD) with Alzheimer disease (AD) in this sample...
  19. ncbi request reprint Mood improvement reduces memory complaints in depressed patients
    R Antikainen
    Kuopio University Hospital, Department of Psychiatry, P O Box 1777, 70211 Kuopio, Finland
    Eur Arch Psychiatry Clin Neurosci 251:6-11. 2001
    ..The aim was to examine associations between memory complaints, cognitive performance and mood in 174 adult, clinically depressed, neurologically healthy patients at baseline and during six months of follow-up...