Research Topics
Species | T HanninenSummaryAffiliation: Kuopio University Hospital Country: Finland Publications
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Detail Information
Publications
Prevalence of mild cognitive impairment: a population-based study in elderly subjectsT Hanninen
Department of Neuroscience and Neurology, University of Kuopio, Finland
Acta Neurol Scand 106:148-54. 2002..In follow-up studies, more than 50% of MCI subjects have been converted to dementia in 3-4 years. However, the epidemiology of MCI is not well known. This study was designed to determine the prevalence of MCI in an elderly population...
Age-associated memory impairment. Normal aging or warning of dementia?T Hanninen
Department of Neurology, Kuopio University Hospital, Finland
Drugs Aging 11:480-9. 1997..More reliable diagnostic approaches are needed for use in studies that are attempting to identify the risk factors for dementia or to find a treatment for very early dementia...
Midlife vascular risk factors and late-life mild cognitive impairment: A population-based studyM Kivipelto
Department of Neuroscience and Neurology, University of Kuopio, Finland
Neurology 56:1683-9. 2001....
Cognitive function in an elderly population with persistent impaired glucose toleranceM Vanhanen
Department of Neurology, Kuopio University Hospital, Finland
Diabetes Care 21:398-402. 1998..To study cognitive function in an elderly population with persistent impaired glucose tolerance (IGT)...
Fragile-X: neuropsychological test performance, CGG triplet repeat lengths, and hippocampal volumesP Jakala
Department of Neuroscience and Neurology, University Hospital and University of Kuopio, Finland
J Clin Invest 100:331-8. 1997..The data suggest minor abnormalities in temporal lobe structures in adult fra(X) subjects with fM...
Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based studyM Kivipelto
Department of Neuroscience and Neurology, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
BMJ 322:1447-51. 2001..To examine the relation of midlife raised blood pressure and serum cholesterol concentrations to Alzheimer's disease in later life...
Diagnosis of Alzheimer's disease: MRI of the hippocampus vs delayed recallM P Laakso
Department of Neurology, Kuopio University Hospital, Kuopio, Finland
Neuropsychologia 38:579-84. 2000..93 for the left hippocampus and 0.96 for the VRT. These data suggest that assessment of delayed recall with the VRT is of high diagnostic accuracy, and may surpass the diagnostic accuracy of hippocampal volumetry...
Plasma Abeta42 and Abeta40 as markers of cognitive change in follow-up: a prospective, longitudinal, population-based cohort studyT T Seppälä
Department of Neurology, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland
J Neurol Neurosurg Psychiatry 81:1123-7. 2010..However, changes in plasma Aβ levels during repeated testing may be helpful in the prediction and evaluation of progression of the incipient AD or mild cognitive impairment...
Heterogeneity of cerebral perfusion 1 week after haemorrhage is an independent predictor of clinical outcome in patients with aneurysmal subarachnoid haemorrhageT Mustonen
Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland
J Neurol Neurosurg Psychiatry 79:1128-33. 2008....
Apolipoprotein E epsilon 4 allele is associated with increased atrophy in progressive mild cognitive impairment: a voxel-based morphometric studyA Hämäläinen
Department of Neuroscience and Neurology, University of Kuopio and Brain Research Unit, Clinical Research Center, Mediteknia, Kuopio, Finland
Neurodegener Dis 5:186-9. 2008..The apolipoprotein E (APOE) epsilon4 allele is a risk factor for Alzheimer's disease. Earlier studies have shown differences in brain structure according to the APOE epsilon4 status...
APOE-epsilon4 is associated with weight loss in women with AD: a population-based studyM Vanhanen
Department of Neurology of the Kuopio University Hospital, Finland
Neurology 56:655-9. 2001..To investigate whether the APOE-epsilon4 allele is associated with weight loss in patients with AD or in nondemented elderly subjects...
Atrophic enlargement of CSF volume after subarachnoid hemorrhage: correlation with neuropsychological outcomeP Bendel
Department of Clinical Radiology, Kuopio University Hospital and University of Kuopio, Finland
AJNR Am J Neuroradiol 31:370-6. 2010..Our aim was to quantify the late ventricular dilation and volumes of the CSF spaces after aSAH and to determine if they correlate with neurologic and cognitive impairments frequently detected in these patients...
CERAD-neuropsychological battery in screening mild Alzheimer's diseaseM Sotaniemi
Department of Psychology, Institute of Behavioural Sciences, University of Helsinki, Finland
Acta Neurol Scand 125:16-23. 2012..However, some of its parts need reassessment and focusing. The goal of this study was to examine the sensitivity and specificity of the subtests and their cut-off points most appropriate for identifying mild Alzheimer's disease (AD)...
Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: a longitudinal studyB Hooshmand
Aging Research Center, KarolinskaInstitutet, Stockholm, Sweden
J Intern Med 271:204-12. 2012....
Subarachnoid hemorrhage is followed by temporomesial volume loss: MRI volumetric studyP Bendel
Department of Clinical Radiology, Kuopio University Hospital, Kuopio University, Kuopio, Finland
Neurology 67:575-82. 2006..To assess whether subarachnoid hemorrhage (SAH) and its treatment is followed by volume loss in temporomesial structures...
Polymorphisms in the CYP19 gene confer increased risk for Alzheimer diseaseS Iivonen
Department of Neuroscience and Neurology, University Hospital and University of Kuopio, Finland
Neurology 62:1170-6. 2004..Aromatase is encoded by the CYP19 gene located at 15q21.1, a chromosomal region in linkage disequilibrium (LD) with Alzheimer disease (AD) in this sample...
Mood improvement reduces memory complaints in depressed patientsR Antikainen
Kuopio University Hospital, Department of Psychiatry, P O Box 1777, 70211 Kuopio, Finland
Eur Arch Psychiatry Clin Neurosci 251:6-11. 2001..The aim was to examine associations between memory complaints, cognitive performance and mood in 174 adult, clinically depressed, neurologically healthy patients at baseline and during six months of follow-up...
