Research Topics
Genomes and GenesSpecies | Matti J ValimakiSummaryAffiliation: Helsinki University Central Hospital Country: Finland Publications
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Detail Information
Publications
Quality of life in treated patients with acromegalyRitva Kauppinen-Mäkelin
Department of Internal Medicine, Jorvi Hospital, FIN 02740 Espoo, Finland
J Clin Endocrinol Metab 91:3891-6. 2006..It is not known to what extent quality of life of patients treated for acromegaly is dependent on levels of GH and IGF-I attained...
The effects of transdermal estrogen therapy on bone mass and turnover in early postmenopausal smokers: a prospective, controlled studyMatti J Valimaki
Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, FIN 00290 Helsinki, Finland
Am J Obstet Gynecol 189:1213-20. 2003..The purpose of this study was to investigate whether smoking reduces the effects of transdermal estrogen replacement therapy on bone...
Quantitative ultrasound variables of the heel in Finnish men aged 18-20 yr: predictors, relationship to bone mineral content, and changes during military serviceV V Välimäki
Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, FI 00029 Helsinki, HUS, Finland
Osteoporos Int 17:1763-71. 2006..Determinants of BUA and SOS and their changes during military service-associated physical training were studied in 196 army recruits and 50 control men, aged 18-20 years...
Serum estradiol, testosterone, and sex hormone-binding globulin as regulators of peak bone mass and bone turnover rate in young Finnish menVille Valtteri Välimäki
Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
J Clin Endocrinol Metab 89:3785-9. 2004..Moreover, serum SHBG appeared to be an independent positive predictor of bone turnover rate, which also positively associated with serum 25-hydroxyvitamin-D levels...
Risk factors for clinical stress fractures in male military recruits: a prospective cohort studyVille Valtteri Välimäki
Department of Medicine, Division of Endocrinology, Helsinki University Central Hospital, FIN 00290 Helsinki, Finland
Bone 37:267-73. 2005..Given the poor vitamin D status of young Finnish men, intervention studies of vitamin D supplementation to lower serum PTH levels and to possibly reduce the incidence of stress fractures are warranted...
Vitamin D status as a determinant of peak bone mass in young Finnish menVille Valtteri Välimäki
Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, FIN 00290 Helsinki, Finland
J Clin Endocrinol Metab 89:76-80. 2004....
Effects of alendronate and hormone replacement therapy, alone and in combination, on bone mass and markers of bone turnover in elderly women with osteoporosisSirpa Eviö
Department of Obstetrics and Gynecology, Helsinki University Central Hospital, FIN 00029 HUS Helsinki, Finland
J Clin Endocrinol Metab 89:626-31. 2004..In terms of BMD changes, the single treatments were equally effective, but the reductions in bone markers were less with HRT than with alendronate...
The same annual dose of 292000 IU of vitamin D (cholecalciferol) on either daily or four monthly basis for elderly women: 1-year comparative study of the effects on serum 25(OH)D concentrations and renal functionTuula Pekkarinen
Department of Internal Medicine, Peijas Hospital, Helsinki University Central Hospital, Vantaa, Finland
Clin Endocrinol (Oxf) 72:455-61. 2010..We compared the efficacy and safety of two oral dosages (800 IU daily or 97333 IU four monthly) of vitamin D(3) resulting in the equal annual dose of 292000 IU...
The relation of the XbaI and PvuII polymorphisms of the estrogen receptor gene and the CAG repeat polymorphism of the androgen receptor gene to peak bone mass and bone turnover rate among young healthy menVille Valtteri Välimäki
Division of Endocrinology, Helsinki University Central Hospital, 00290, Helsinki, Finland
Osteoporos Int 16:1633-40. 2005..Our study does not support the view that the XbaI and PvuII polymorphisms of the ER gene and the CAG polymorphism of the AR gene would have a substantial impact on the development of peak bone mass in young Finnish men...
Post-ablative serum thyroglobulin is an independent predictor of recurrence in low-risk differentiated thyroid carcinoma: a 16-year follow-up studyHanna Pelttari
Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, PO Box 340, FI 00290 Helsinki, Finland
Eur J Endocrinol 163:757-63. 2010..To study whether post-surgical and/or post-ablative thyroglobulin (Tg) concentrations may serve as independent predictors of disease recurrence in patients treated for TNM stage I or II well-differentiated thyroid carcinoma (WDTC)...
The A1330V polymorphism of the low-density lipoprotein receptor-related protein 5 gene (LRP5) associates with low peak bone mass in young healthy menAnne Saarinen
Folkhälsan Institute of Genetics and Department of Medical Genetics, University of Helsinki, Helsinki, Finland
Bone 40:1006-12. 2007..Whether this is due to influence on bone mass acquisition or on bone loss thereafter has not been established...
Serum 25(OH)D3 vitamin status of elderly Finnish women is suboptimal even after summer sunshine but is not associated with bone density or turnoverTuula Pekkarinen
Department of Internal Medicine, Peijas Hospital, Helsinki University Central Hospital, Helsinki, Finland
Eur J Endocrinol 162:183-9. 2010..We evaluated vitamin D status of elderly Finnish women in light of these definitions, its relationship to bone mineral density (BMD) and turnover, and improvement by summer sunshine...
BRAF V600E mutation does not predict recurrence after long-term follow-up in TNM stage I or II papillary thyroid carcinoma patientsHanna Pelttari
Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, Finland
APMIS 120:380-6. 2012..2 cm, 21% vs 35% and 6% vs 12%, respectively, all p = NS). Taken together, BRAF V600E is common in Finnish patients with low-risk PTC but does not predict recurrence after long-term follow-up after initial treatment with TTE and RRA...
Serum tartrate-resistant acid phosphatase 5b or amino-terminal propeptide of type I procollagen for monitoring bisphosphonate therapy in postmenopausal osteoporosis?Matti J Valimaki
Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, Finland
Clin Chem 51:2382-5. 2005
Effects of risedronate 5 mg/d on bone mineral density and bone turnover markers in late-postmenopausal women with osteopenia: a multinational, 24-month, randomized, double-blind, placebo-controlled, parallel-group, phase III trialMatti J Valimaki
Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
Clin Ther 29:1937-49. 2007..Although the effects of risedronate in preventing frac- tures has been established, its effects in maintaining or increasing BMD in osteopenia have not...
Serum TSH reference interval in healthy Finnish adults using the Abbott Architect 2000i AnalyzerCamilla Schalin-Jantti
Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, Finland
Scand J Clin Lab Invest 71:344-9. 2011..The objective was to redefine the TSH reference interval in the adult Finnish population. The current reference interval for the widely used Abbott Architect method in Finland is 0.4-4.0 mU/L...
Long-term outcome of 495 TNM stage I or II patients with differentiated thyroid carcinoma followed up with neck ultrasonography and thyroglobulin measurements on T4 treatmentHanna Pelttari
Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
Clin Endocrinol (Oxf) 69:323-31. 2008..We evaluated the safety and efficacy of a surveillance paradigm comprising yearly T(4)-suppressed Tg measurements and neck US every second year, with an increase in Tg to a detectable level being a prompt indication for DxWBS...
Manifestation, management and molecular analysis of candidate genes in two rare cases of thyrotoxic hypokalemic periodic paralysisCamilla Schalin-Jantti
Division of Endocrinology, Department of Medicine, University of Helsinki, Finland
Horm Res 63:139-44. 2005..Ion channel gene mutations may underlie these diseases. We describe the first pediatric and a rare adult Caucasian case of THypoKPP in Finland...
A nationwide survey of mortality in acromegalyRitva Kauppinen-Mäkelin
Department of Internal Medicine, Jorvi Hospital, FIN 02740 Espoo, Finland
J Clin Endocrinol Metab 90:4081-6. 2005..Increased mortality in acromegaly has been confined to those with posttreatment basal GH of 2.5 microg/liter or greater, but the impact of IGF-I and pituitary radiotherapy on mortality has remained controversial...
The novel WHO 2010 classification for gastrointestinal neuroendocrine tumours correlates well with the metastatic potential of rectal neuroendocrine tumoursJuha Jernman
Department of Pathology, Haartman Institute and HUSLAB, Helsinki University Central Hospital, Haarmaninkatu 3, Helsinki, Finland
Neuroendocrinology 95:317-24. 2012..The WHO 2010 classification of NETs predicts the metastatic potential of rectal NETs better than the WHO 2000 classification...
Health-related quality of life in long-term follow-up of patients with cured TNM Stage I or II differentiated thyroid carcinomaHanna Pelttari
Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
Clin Endocrinol (Oxf) 70:493-7. 2009..The purpose of this study was to assess the impact of cured low-risk differentiated thyroid carcinoma (DTC) on health-related quality of life (HRQoL) after long-term follow-up...
Effect of sex and assay method on serum concentrations of growth hormone in patients with acromegaly and in healthy controlsHelene Markkanen
Department of Clinical Chemistry, Helsinki University Hospital, Helsinki, Finland
Clin Chem 52:468-73. 2006..A nadir value <1 microg/L is commonly used to define a normal response, but some authors suggest lower cutoff values...
The effect of hormone therapy on the health-related quality of life in elderly womenSirpa Eviö
Department of Obstetrics and Gynecology, Helsinki University Central Hospital, PB 140, 00029 Helsinki, Finland
Maturitas 56:122-8. 2007..The purpose of this study was to compare the health-related quality of life (HRQoL) of elderly users and non-users of hormone therapy (HT)...
Parathyroid hormone treatment improves pain and fracture healing in adult hypophosphatasiaCamilla Schalin-Jantti
Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, P O Box 340, FI 00290 Helsinki, Finland
J Clin Endocrinol Metab 95:5174-9. 2010..Increased S-ALP and fracture repair were reported in two patients treated with teriparatide, PTH 1-34. The effects of full-length PTH 1-84 have not been studied...
