Reijo Tilvis

Summary

Affiliation: Helsinki University Central Hospital
Country: Finland

Publications

  1. ncbi request reprint Statin treatment is associated with clearly reduced mortality risk of cardiovascular patients aged 75 years and older
    Timo E Strandberg
    J Gerontol A Biol Sci Med Sci 63:213-4; author reply 214. 2008
  2. ncbi request reprint [Pain in the elderly]
    Reijo Tilvis
    HYKS, sisätautien toimiala, yleissisätautien ja geriatrian klinikat PL 340, 00029 HUS
    Duodecim 120:223-7. 2004
  3. ncbi request reprint Predictors of cognitive decline and mortality of aged people over a 10-year period
    Reijo S Tilvis
    Geriatric Clinic, Department of Medicine, Helsinki University Central Hospital, Finland
    J Gerontol A Biol Sci Med Sci 59:268-74. 2004
  4. doi request reprint Laboratory tests as predictors of the antihypertensive effects of amlodipine, bisoprolol, hydrochlorothiazide and losartan in men: results from the randomized, double-blind, crossover GENRES Study
    Timo Suonsyrja
    Department of Medicine, University of Helsinki, and Biomedicum Helsinki, Helsinki, Finland
    J Hypertens 26:1250-6. 2008
  5. doi request reprint Parathyroid hormone as a mortality predictor in frail aged inpatients
    Mikko Bjorkman
    Helsinki University Central Hospital, Helsinki, Finland
    Gerontology 55:601-6. 2009
  6. ncbi request reprint Vitamin D supplementation has no major effect on pain or pain behavior in bedridden geriatric patients with advanced dementia
    Mikko Bjorkman
    Clinics of Internal Medicine and Geriatrics, Helsinki University Central Hospital, POB 340, FI 00029 HUS, Helsinki, Finland
    Aging Clin Exp Res 20:316-21. 2008
  7. ncbi request reprint Predictors of antihypertensive drug responses: initial data from a placebo-controlled, randomized, cross-over study with four antihypertensive drugs (The GENRES Study)
    Timo P Hiltunen
    Department of Medicine, University of Helsinki, and Biomedicum Helsinki, Helsinki, Finland
    Am J Hypertens 20:311-8. 2007
  8. ncbi request reprint Benefits of optimising drug treatment in home-dwelling elderly patients with coronary artery disease
    Timo Strandberg
    Department of Medicine, Geriatric Clinic, University of Helsinki, Helsinki, Finland
    Drugs Aging 20:585-95. 2003
  9. ncbi request reprint Prognostic significance of delirium in frail older people
    Kaisu H Pitkala
    Department of Medicine, Geriatric Clinic, Helsinki University Hospital, Helsinki, Finland
    Dement Geriatr Cogn Disord 19:158-63. 2005
  10. doi request reprint Predisposing and precipitating factors for delirium in a frail geriatric population
    Jouko V Laurila
    Departments of Internal Medicine and Geriatrics corrected Helsinki University Central Hospital, Finland
    J Psychosom Res 65:249-54. 2008

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Statin treatment is associated with clearly reduced mortality risk of cardiovascular patients aged 75 years and older
    Timo E Strandberg
    J Gerontol A Biol Sci Med Sci 63:213-4; author reply 214. 2008
  2. ncbi request reprint [Pain in the elderly]
    Reijo Tilvis
    HYKS, sisätautien toimiala, yleissisätautien ja geriatrian klinikat PL 340, 00029 HUS
    Duodecim 120:223-7. 2004
  3. ncbi request reprint Predictors of cognitive decline and mortality of aged people over a 10-year period
    Reijo S Tilvis
    Geriatric Clinic, Department of Medicine, Helsinki University Central Hospital, Finland
    J Gerontol A Biol Sci Med Sci 59:268-74. 2004
    ..According to the hypothesis of our 10-year prospective study, the predictive values of different risk indicators change over time in a general 75+ population...
  4. doi request reprint Laboratory tests as predictors of the antihypertensive effects of amlodipine, bisoprolol, hydrochlorothiazide and losartan in men: results from the randomized, double-blind, crossover GENRES Study
    Timo Suonsyrja
    Department of Medicine, University of Helsinki, and Biomedicum Helsinki, Helsinki, Finland
    J Hypertens 26:1250-6. 2008
    ..To improve optimization of antihypertensive therapy, we analyzed correlations of relevant laboratory tests with blood pressure responses to four antihypertensive monotherapies...
  5. doi request reprint Parathyroid hormone as a mortality predictor in frail aged inpatients
    Mikko Bjorkman
    Helsinki University Central Hospital, Helsinki, Finland
    Gerontology 55:601-6. 2009
    ..Some prospective cohort studies have associated parathyroid hormone (PTH) levels with survival independently of renal function, calcaemic and vitamin D status in the elderly...
  6. ncbi request reprint Vitamin D supplementation has no major effect on pain or pain behavior in bedridden geriatric patients with advanced dementia
    Mikko Bjorkman
    Clinics of Internal Medicine and Geriatrics, Helsinki University Central Hospital, POB 340, FI 00029 HUS, Helsinki, Finland
    Aging Clin Exp Res 20:316-21. 2008
    ..This randomized double-blind placebo controlled trial addressed the association between pain and vitamin D deficiency and the effects of vitamin D supplementation on pain in institutionalized aged patients...
  7. ncbi request reprint Predictors of antihypertensive drug responses: initial data from a placebo-controlled, randomized, cross-over study with four antihypertensive drugs (The GENRES Study)
    Timo P Hiltunen
    Department of Medicine, University of Helsinki, and Biomedicum Helsinki, Helsinki, Finland
    Am J Hypertens 20:311-8. 2007
    ..Only a minority of hypertensive individuals is adequately controlled for their hypertension, partially because reliable predictors for efficient antihypertensive drug therapy are lacking...
  8. ncbi request reprint Benefits of optimising drug treatment in home-dwelling elderly patients with coronary artery disease
    Timo Strandberg
    Department of Medicine, Geriatric Clinic, University of Helsinki, Helsinki, Finland
    Drugs Aging 20:585-95. 2003
    ..At the societal level, this would be reflected in fewer hospitalisations and institutionalisations, which means decreased cost of elderly care...
  9. ncbi request reprint Prognostic significance of delirium in frail older people
    Kaisu H Pitkala
    Department of Medicine, Geriatric Clinic, Helsinki University Hospital, Helsinki, Finland
    Dement Geriatr Cogn Disord 19:158-63. 2005
    ..86, 95% CI 1.1-3.1), at 2 years (OR 1.76, 95% CI 1.1-2.8), and for permanent institutionalization (OR 2.45, 95% CI 1.2-4.9). Delirious patients with prior dementia tended to have a better prognosis than those without...
  10. doi request reprint Predisposing and precipitating factors for delirium in a frail geriatric population
    Jouko V Laurila
    Departments of Internal Medicine and Geriatrics corrected Helsinki University Central Hospital, Finland
    J Psychosom Res 65:249-54. 2008
    ..The aim of this study was to assess the possible predisposing aetiologic and short-term precipitating factors for delirium in acutely ill hospital patients with a heavy burden of comorbidities and medications...
  11. ncbi request reprint Inappropriate drug prescribing in home-dwelling, elderly patients: a population-based survey
    Kaisu H Pitkala
    Department of Medicine, Geriatric Clinic, Helsinki University Hospital, Finland
    Arch Intern Med 162:1707-12. 2002
    ..In 1997, a US expert panel developed explicit criteria on potentially inappropriate drugs for the general elderly population...
  12. ncbi request reprint Management of nonmalignant pain in home-dwelling older people: a population-based survey
    Kaisu H Pitkala
    Helsinki University Hospital, Department of Medicine, Geriatric Clinic, Helsinki, Finland
    J Am Geriatr Soc 50:1861-5. 2002
    ....
  13. ncbi request reprint Impact of viral and bacterial burden on cognitive impairment in elderly persons with cardiovascular diseases
    Timo E Strandberg
    Department of Medicine, Geriatric Clinic, University of Helsinki, PO Box 340, FIN 00029 HUS Helsinki, Finland
    Stroke 34:2126-31. 2003
    ..Inflammation and infectious etiology have been implicated in the pathogenesis of dementia. We sought to investigate whether the seropositivity of common infections was associated with cognitive function...
  14. ncbi request reprint Possibilities of multifactorial cardiovascular disease prevention in patients aged 75 and older: a randomized controlled trial: Drugs and Evidence Based Medicine in the Elderly (DEBATE) Study
    Timo E Strandberg
    Department of Medicine, Geriatric Clinic and Division of Cardiology, University of Helsinki, Helsinki, Finland
    Eur Heart J 24:1216-22. 2003
    ..The aim of this pre-planned, first-year analysis of the Drugs and Evidence-Based Medicine in the Elderly (DEBATE) Study was to determine the feasibility of prevention efforts in elderly cardiovascular patients...
  15. ncbi request reprint Interaction of herpesviridae, APOE gene, and education in cognitive impairment
    Timo E Strandberg
    Department of Medicine, Geriatric Clinic, University of Helsinki, P O Box 340, FIN 00029 HUS, Finland
    Neurobiol Aging 26:1001-4. 2005
    ....
  16. ncbi request reprint Delirium among patients with and without dementia: does the diagnosis according to the DSM-IV differ from the previous classifications?
    Jouko V Laurila
    Department of Medicine, Helsinki University Hospital, Geriatric Clinic, Helsinki, Finland
    Int J Geriatr Psychiatry 19:271-7. 2004
    ..It is not known how DSM-IV classification, compared with the DSM-III, DSM-III-R, and ICD-10, identifies delirium among individuals with and without dementia and whether the symptom profiles differ between these two subgroups...
  17. pmc Exercise rehabilitation on home-dwelling patients with Alzheimer's disease--a randomized, controlled trial. Study protocol
    Kaisu H Pitkala
    Unit of General Practice, Helsinki University Central Hospital, University of Helsinki, PO Box 20, 00014 University of Helsinki, Finland
    Trials 11:92. 2010
    ..The aim of this study is to investigate the effectiveness of intensive exercise rehabilitation lasting for one year on mobility and physical functioning of home-dwelling patients with AD...
  18. ncbi request reprint Vitamin D supplementation has minor effects on parathyroid hormone and bone turnover markers in vitamin D-deficient bedridden older patients
    Mikko Bjorkman
    Clinics of Internal Medicine and Geriatrics, Helsinki University Central Hospital, Helsinki, Finland, POB 340, FI 00290 HUS
    Age Ageing 37:25-31. 2008
    ..to evaluate the effects of vitamin D supplementation on parathyroid function and bone turnover in aged, chronically immobile patients...
  19. doi request reprint Does elevated parathyroid hormone concentration predict cognitive decline in older people?
    Mikko P Björkman
    Clinics of Internal Medicine and Geriatrics, Helsinki University Central Hospital, Helsinki, Finland
    Aging Clin Exp Res 22:164-9. 2010
    ..This association was evaluated in random persons of age cohorts of 75, 80 and 85 years in a 10- year longitudinal prospective study...
  20. doi request reprint The effect of smoking in midlife on health-related quality of life in old age: a 26-year prospective study
    Arto Y Strandberg
    Department of Medicine, Geriatric Clinic, University of Helsinki, PL 340, 00029 Helsinki, Finland
    Arch Intern Med 168:1968-74. 2008
    ..This study evaluates the long-term effect of smoking in midlife on health-related quality of life (HRQoL) in old age...
  21. ncbi request reprint The impact of different diagnostic criteria on prevalence rates for delirium
    Jouko V Laurila
    Geriatric Clinic, Department of Medicine, Helsinki University Hospital, HUS, Finland
    Dement Geriatr Cogn Disord 16:156-62. 2003
    ..The DSM-IV and ICD-10 had the largest number of patients not overlapping with any other diagnostic group. The newest DSM-IV classification found more cases of delirium especially among acutely ill, hospitalized patients...
  22. ncbi request reprint Detection and documentation of dementia and delirium in acute geriatric wards
    Jouko V Laurila
    Department of Medicine, Helsinki University Hospital, Geriatric Clinic, Helsinki, Finland
    Gen Hosp Psychiatry 26:31-5. 2004
    ..3%) in medical records. In 64/77 (83.1%) cases signs of confusion were recorded in nurses' notes. Poor detection and documentation may lead to undertreatment of both disorders...
  23. ncbi request reprint Left ventricular hypertrophy and blood pressure as predictors of cognitive decline in old age
    Mervi Kähönen-Väre
    Clinic of Geriatrics, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Aging Clin Exp Res 16:147-52. 2004
    ..The impact of history of hypertension, present BP levels, and left ventricular hypertrophy (LVH) on cognition was investigated in a 10-year follow-up study of an aged population...
  24. doi request reprint Elevated serum parathyroid hormone predicts impaired survival prognosis in a general aged population
    Mikko P Björkman
    Clinics of Internal Medicine and Geriatrics, Helsinki University Central Hospital, POB 340, FI 00290 HUS Helsinki, Finland
    Eur J Endocrinol 158:749-53. 2008
    ..In order to evaluate the predictive value of elevated serum PTH during the last years of life, random persons of age cohorts of 75, 80 and 85 years were followed for 17 years...
  25. ncbi request reprint Impact of different diagnostic criteria on prognosis of delirium: a prospective study
    Jouko V Laurila
    Geriatric Clinic, Department of Medicine, Helsinki University Hospital, Helsinki, Finland
    Dement Geriatr Cogn Disord 18:240-4. 2004
    ..The DSM-IV has simplified the criteria of delirium. It identifies new, acutely ill and relatively nondependent subjects as delirious who share the poor prognosis of patients diagnosed with the previous criteria...
  26. doi request reprint Low parathyroid hormone levels in bedridden geriatric patients with vitamin D deficiency
    Mikko P Björkman
    Helsinki University Central Hospital, Clinic of Internal Medicine, POB 340, HUS FI 00029, Helsinki, Finland
    J Am Geriatr Soc 57:1045-50. 2009
    ..To identify the clinical conditions associated with low parathyroid hormone (PTH) in patients with vitamin D deficiency and to evaluate the stability of the blunted PTH response to vitamin D deficiency over 6 months...
  27. ncbi request reprint Periodontal disease and mortality in an aged population
    Shilpi Ajwani
    Department of Oral Rehabilitation, School of Dentistry, University of Otago, New Zealand
    Spec Care Dentist 23:125-30. 2003
    ..These results suggest that periodontitis influences the pathogenesis and outcome of cardiovascular disease, especially in individuals who also have evidence of a systemic inflammatory reaction...
  28. ncbi request reprint Living will, resuscitation preferences, and attitudes towards life in an aged population
    Marja Liisa Laakkonen
    Helsinki City Hospital Koskela, Helsinki, Finland
    Gerontology 50:247-54. 2004
    ..The growth of life-sustaining medical technology and greater attention to medical care at the end of life have provoked interest in issues related to advance care planning...
  29. ncbi request reprint The association between weight gain up to midlife, 30-year mortality, and quality of life in older men
    Timo E Strandberg
    Arch Intern Med 167:2260-1. 2007
  30. ncbi request reprint Multicomponent geriatric intervention for elderly inpatients with delirium: effects on costs and health-related quality of life
    Kaisu H Pitkala
    Unit of General Practice, University of Helsinki, Finland
    J Gerontol A Biol Sci Med Sci 63:56-61. 2008
    ..We studied the effects of multicomponent geriatric treatment on costs of care and HRQoL in delirious inpatients...
  31. ncbi request reprint Neither atypical nor conventional antipsychotics increase mortality or hospital admissions among elderly patients with dementia: a two-year prospective study
    Minna M Raivio
    Memory Research and Treatment Centers Finland Medical Center Hemo Oy, Lahti, Finland
    Am J Geriatr Psychiatry 15:416-24. 2007
    ..Antipsychotics are widely used to manage behavioral disorders in patients with dementia. Recently, serious concerns have been raised about the stroke and mortality risk of atypical antipsychotics when administered to patients with dementia...
  32. ncbi request reprint Alcoholic beverage preference, 29-year mortality, and quality of life in men in old age
    Timo E Strandberg
    Department of Public Health Science and General Practice, University of Oulu, Finland
    J Gerontol A Biol Sci Med Sci 62:213-8. 2007
    ..We compared 29-year mortality and quality of life in old age by alcoholic beverage preference (beer, wine, or spirits) in a cohort of men whose socioeconomic status was similar in their adult life...
  33. ncbi request reprint Psychotropic medication and stroke outcome
    Minna M Raivio
    Am J Psychiatry 162:1027; author reply 1027-8. 2005
  34. ncbi request reprint Cardiovascular risk in midlife and psychological well-being among older men
    Timo E Strandberg
    Department of Public Health Science and General Practice, University of Oulu, Oulu, Finland
    Arch Intern Med 166:2266-71. 2006
    ..We investigated whether cardiovascular disease risk in midlife is related to psychological well-being in older men (aged 69-84 years old)...
  35. ncbi request reprint Use of inappropriate medications and their prognostic significance among in-hospital and nursing home patients with and without dementia in Finland
    Minna M Raivio
    Department of General Internal Medicine and Geriatrics, University of Helsinki, Finland
    Drugs Aging 23:333-43. 2006
    ..This study examines the use of inappropriate drugs and their impact on mortality and use of health services among Finnish elderly nursing home and hospital patients. Patients with dementia were studied as a special subgroup...
  36. ncbi request reprint Multicomponent geriatric intervention for elderly inpatients with delirium: a randomized, controlled trial
    Kaisu H Pitkala
    The Central Union for the Welfare of the Aged, Malmin Kauppatie 26, 00700 Helsinki, Finland
    J Gerontol A Biol Sci Med Sci 61:176-81. 2006
    ..Treatment is mainly based on common sense with wide variations in practice. We investigated whether intensified, multicomponent geriatric treatment could improve the prognosis of delirious patients...
  37. ncbi request reprint Cholesterol and glucose metabolism and recurrent cardiovascular events among the elderly: a prospective study
    Timo E Strandberg
    Department of Public Health Science and General Practice, University of Oulu, Oulu, Finland
    J Am Coll Cardiol 48:708-14. 2006
    ....
  38. ncbi request reprint Social contacts and their relationship to loneliness among aged people - a population-based study
    Pirkko E Routasalo
    Department of Nursing Science, University of Turku, Finland
    Gerontology 52:181-7. 2006
    ..Emotional loneliness and social isolation are major problems in old age. These concepts are interrelated and often used interchangeably, but few studies have investigated them simultaneously thus trying to clarify their relationship...
  39. ncbi request reprint Advance orders to limit therapy in 67 long-term care facilities in Finland
    Marja Liisa Laakkonen
    Helsinki City Hospital Koskela, P O Box 6410, FIN 00099 Helsinki, Finland
    Resuscitation 61:333-9. 2004
    ..To assess the documentation of a do-not-attempt-resuscitation (DNAR) or do-not-hospitalize (DNH) orders in the medical record and to determine factors related to these orders...
  40. ncbi request reprint Multifactorial intervention to prevent recurrent cardiovascular events in patients 75 years or older: the Drugs and Evidence-Based Medicine in the Elderly (DEBATE) study: a randomized, controlled trial
    Timo E Strandberg
    Department of Public Health Science and General Practice, University of Oulu, University Hospital, Oulu, Finland
    Am Heart J 152:585-92. 2006
    ..We aimed to examine whether better use of preventive methods and treatments of cardiovascular disease would reduce recurrent events in home-dwelling patients 75 years or older...
  41. ncbi request reprint Physical and cognitive functioning and resuscitation preferences of aged patients
    Marja Lilsa Laakkonen
    J Am Geriatr Soc 53:168-70. 2005
  42. ncbi request reprint Interest in healthy lifestyle and adherence to medications: Impact on mortality among elderly cardiovascular patients in the DEBATE Study
    Kaisu H Pitkala
    University of Helsinki, Department of Primary Care and General Practice, Helsinki, Finland
    Patient Educ Couns 67:44-9. 2007
    ..We examined how a patient-centered consultation can help the physician to evaluate older patients' adherence to medical care and a healthy lifestyle. We hypothesised that an accurate estimate of adherence should be shown in their prognosis...
  43. ncbi request reprint Older people's reasoning for resuscitation preferences and their role in the decision-making process
    Marja Liisa Laakkonen
    Helsinki City Hospital Koskela, P O Box 6410, FIN 00099 Helsinki, Finland
    Resuscitation 65:165-71. 2005
    ..To investigate older patients' reasoning for their cardiopulmonary resuscitation (CPR) preferences and the related decision-making process (DMP)...