Research Topics
Species | Reijo TilvisSummaryAffiliation: Helsinki University Central Hospital Country: Finland Publications
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Detail Information
Publications
Statin treatment is associated with clearly reduced mortality risk of cardiovascular patients aged 75 years and olderTimo E Strandberg
J Gerontol A Biol Sci Med Sci 63:213-4; author reply 214. 2008- [Pain in the elderly]Reijo Tilvis
HYKS, , , 00029 HUS
Duodecim 120:223-7. 2004 - Predictors of cognitive decline and mortality of aged people over a 10-year periodReijo S Tilvis
Geriatric Clinic, Department of Medicine, Helsinki University Central Hospital, Finland
J Gerontol A Biol Sci Med Sci 59:268-74. 2004..According to the hypothesis of our 10-year prospective study, the predictive values of different risk indicators change over time in a general 75+ population... 
Laboratory tests as predictors of the antihypertensive effects of amlodipine, bisoprolol, hydrochlorothiazide and losartan in men: results from the randomized, double-blind, crossover GENRES StudyTimo Suonsyrja
Department of Medicine, University of Helsinki, and Biomedicum Helsinki, Helsinki, Finland
J Hypertens 26:1250-6. 2008..To improve optimization of antihypertensive therapy, we analyzed correlations of relevant laboratory tests with blood pressure responses to four antihypertensive monotherapies...- Parathyroid hormone as a mortality predictor in frail aged inpatientsMikko Bjorkman
Helsinki University Central Hospital, Helsinki, Finland
Gerontology 55:601-6. 2009..Some prospective cohort studies have associated parathyroid hormone (PTH) levels with survival independently of renal function, calcaemic and vitamin D status in the elderly... - Vitamin D supplementation has no major effect on pain or pain behavior in bedridden geriatric patients with advanced dementiaMikko Bjorkman
Clinics of Internal Medicine and Geriatrics, Helsinki University Central Hospital, POB 340, FI 00029 HUS, Helsinki, Finland
Aging Clin Exp Res 20:316-21. 2008..This randomized double-blind placebo controlled trial addressed the association between pain and vitamin D deficiency and the effects of vitamin D supplementation on pain in institutionalized aged patients... - Predictors of antihypertensive drug responses: initial data from a placebo-controlled, randomized, cross-over study with four antihypertensive drugs (The GENRES Study)Timo P Hiltunen
Department of Medicine, University of Helsinki, and Biomedicum Helsinki, Helsinki, Finland
Am J Hypertens 20:311-8. 2007..Only a minority of hypertensive individuals is adequately controlled for their hypertension, partially because reliable predictors for efficient antihypertensive drug therapy are lacking... - Benefits of optimising drug treatment in home-dwelling elderly patients with coronary artery diseaseTimo Strandberg
Department of Medicine, Geriatric Clinic, University of Helsinki, Helsinki, Finland
Drugs Aging 20:585-95. 2003..At the societal level, this would be reflected in fewer hospitalisations and institutionalisations, which means decreased cost of elderly care... - Prognostic significance of delirium in frail older peopleKaisu H Pitkala
Department of Medicine, Geriatric Clinic, Helsinki University Hospital, Helsinki, Finland
Dement Geriatr Cogn Disord 19:158-63. 2005..86, 95% CI 1.1-3.1), at 2 years (OR 1.76, 95% CI 1.1-2.8), and for permanent institutionalization (OR 2.45, 95% CI 1.2-4.9). Delirious patients with prior dementia tended to have a better prognosis than those without... - Predisposing and precipitating factors for delirium in a frail geriatric populationJouko V Laurila
Departments of Internal Medicine and Geriatrics corrected Helsinki University Central Hospital, Finland
J Psychosom Res 65:249-54. 2008..The aim of this study was to assess the possible predisposing aetiologic and short-term precipitating factors for delirium in acutely ill hospital patients with a heavy burden of comorbidities and medications... - Inappropriate drug prescribing in home-dwelling, elderly patients: a population-based surveyKaisu H Pitkala
Department of Medicine, Geriatric Clinic, Helsinki University Hospital, Finland
Arch Intern Med 162:1707-12. 2002..In 1997, a US expert panel developed explicit criteria on potentially inappropriate drugs for the general elderly population... - Management of nonmalignant pain in home-dwelling older people: a population-based surveyKaisu H Pitkala
Helsinki University Hospital, Department of Medicine, Geriatric Clinic, Helsinki, Finland
J Am Geriatr Soc 50:1861-5. 2002.... - Impact of viral and bacterial burden on cognitive impairment in elderly persons with cardiovascular diseasesTimo E Strandberg
Department of Medicine, Geriatric Clinic, University of Helsinki, PO Box 340, FIN 00029 HUS Helsinki, Finland
Stroke 34:2126-31. 2003..Inflammation and infectious etiology have been implicated in the pathogenesis of dementia. We sought to investigate whether the seropositivity of common infections was associated with cognitive function... - Possibilities of multifactorial cardiovascular disease prevention in patients aged 75 and older: a randomized controlled trial: Drugs and Evidence Based Medicine in the Elderly (DEBATE) StudyTimo E Strandberg
Department of Medicine, Geriatric Clinic and Division of Cardiology, University of Helsinki, Helsinki, Finland
Eur Heart J 24:1216-22. 2003..The aim of this pre-planned, first-year analysis of the Drugs and Evidence-Based Medicine in the Elderly (DEBATE) Study was to determine the feasibility of prevention efforts in elderly cardiovascular patients... - Interaction of herpesviridae, APOE gene, and education in cognitive impairmentTimo E Strandberg
Department of Medicine, Geriatric Clinic, University of Helsinki, P O Box 340, FIN 00029 HUS, Finland
Neurobiol Aging 26:1001-4. 2005.... - Delirium among patients with and without dementia: does the diagnosis according to the DSM-IV differ from the previous classifications?Jouko V Laurila
Department of Medicine, Helsinki University Hospital, Geriatric Clinic, Helsinki, Finland
Int J Geriatr Psychiatry 19:271-7. 2004..It is not known how DSM-IV classification, compared with the DSM-III, DSM-III-R, and ICD-10, identifies delirium among individuals with and without dementia and whether the symptom profiles differ between these two subgroups... 
Exercise rehabilitation on home-dwelling patients with Alzheimer's disease--a randomized, controlled trial. Study protocolKaisu H Pitkala
Unit of General Practice, Helsinki University Central Hospital, University of Helsinki, PO Box 20, 00014 University of Helsinki, Finland
Trials 11:92. 2010..The aim of this study is to investigate the effectiveness of intensive exercise rehabilitation lasting for one year on mobility and physical functioning of home-dwelling patients with AD...- Vitamin D supplementation has minor effects on parathyroid hormone and bone turnover markers in vitamin D-deficient bedridden older patientsMikko Bjorkman
Clinics of Internal Medicine and Geriatrics, Helsinki University Central Hospital, Helsinki, Finland, POB 340, FI 00290 HUS
Age Ageing 37:25-31. 2008..to evaluate the effects of vitamin D supplementation on parathyroid function and bone turnover in aged, chronically immobile patients... - Does elevated parathyroid hormone concentration predict cognitive decline in older people?Mikko P Björkman
Clinics of Internal Medicine and Geriatrics, Helsinki University Central Hospital, Helsinki, Finland
Aging Clin Exp Res 22:164-9. 2010..This association was evaluated in random persons of age cohorts of 75, 80 and 85 years in a 10- year longitudinal prospective study... - The effect of smoking in midlife on health-related quality of life in old age: a 26-year prospective studyArto Y Strandberg
Department of Medicine, Geriatric Clinic, University of Helsinki, PL 340, 00029 Helsinki, Finland
Arch Intern Med 168:1968-74. 2008..This study evaluates the long-term effect of smoking in midlife on health-related quality of life (HRQoL) in old age... - The impact of different diagnostic criteria on prevalence rates for deliriumJouko V Laurila
Geriatric Clinic, Department of Medicine, Helsinki University Hospital, HUS, Finland
Dement Geriatr Cogn Disord 16:156-62. 2003..The DSM-IV and ICD-10 had the largest number of patients not overlapping with any other diagnostic group. The newest DSM-IV classification found more cases of delirium especially among acutely ill, hospitalized patients... - Detection and documentation of dementia and delirium in acute geriatric wardsJouko V Laurila
Department of Medicine, Helsinki University Hospital, Geriatric Clinic, Helsinki, Finland
Gen Hosp Psychiatry 26:31-5. 2004..3%) in medical records. In 64/77 (83.1%) cases signs of confusion were recorded in nurses' notes. Poor detection and documentation may lead to undertreatment of both disorders... - Left ventricular hypertrophy and blood pressure as predictors of cognitive decline in old ageMervi Kähönen-Väre
Clinic of Geriatrics, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
Aging Clin Exp Res 16:147-52. 2004..The impact of history of hypertension, present BP levels, and left ventricular hypertrophy (LVH) on cognition was investigated in a 10-year follow-up study of an aged population... - Elevated serum parathyroid hormone predicts impaired survival prognosis in a general aged populationMikko P Björkman
Clinics of Internal Medicine and Geriatrics, Helsinki University Central Hospital, POB 340, FI 00290 HUS Helsinki, Finland
Eur J Endocrinol 158:749-53. 2008..In order to evaluate the predictive value of elevated serum PTH during the last years of life, random persons of age cohorts of 75, 80 and 85 years were followed for 17 years... - Impact of different diagnostic criteria on prognosis of delirium: a prospective studyJouko V Laurila
Geriatric Clinic, Department of Medicine, Helsinki University Hospital, Helsinki, Finland
Dement Geriatr Cogn Disord 18:240-4. 2004..The DSM-IV has simplified the criteria of delirium. It identifies new, acutely ill and relatively nondependent subjects as delirious who share the poor prognosis of patients diagnosed with the previous criteria... - Low parathyroid hormone levels in bedridden geriatric patients with vitamin D deficiencyMikko P Björkman
Helsinki University Central Hospital, Clinic of Internal Medicine, POB 340, HUS FI 00029, Helsinki, Finland
J Am Geriatr Soc 57:1045-50. 2009..To identify the clinical conditions associated with low parathyroid hormone (PTH) in patients with vitamin D deficiency and to evaluate the stability of the blunted PTH response to vitamin D deficiency over 6 months... - Periodontal disease and mortality in an aged populationShilpi Ajwani
Department of Oral Rehabilitation, School of Dentistry, University of Otago, New Zealand
Spec Care Dentist 23:125-30. 2003..These results suggest that periodontitis influences the pathogenesis and outcome of cardiovascular disease, especially in individuals who also have evidence of a systemic inflammatory reaction... - Living will, resuscitation preferences, and attitudes towards life in an aged populationMarja Liisa Laakkonen
Helsinki City Hospital Koskela, Helsinki, Finland
Gerontology 50:247-54. 2004..The growth of life-sustaining medical technology and greater attention to medical care at the end of life have provoked interest in issues related to advance care planning... - The association between weight gain up to midlife, 30-year mortality, and quality of life in older menTimo E Strandberg
Arch Intern Med 167:2260-1. 2007 - Multicomponent geriatric intervention for elderly inpatients with delirium: effects on costs and health-related quality of lifeKaisu H Pitkala
Unit of General Practice, University of Helsinki, Finland
J Gerontol A Biol Sci Med Sci 63:56-61. 2008..We studied the effects of multicomponent geriatric treatment on costs of care and HRQoL in delirious inpatients... - Neither atypical nor conventional antipsychotics increase mortality or hospital admissions among elderly patients with dementia: a two-year prospective studyMinna M Raivio
Memory Research and Treatment Centers Finland Medical Center Hemo Oy, Lahti, Finland
Am J Geriatr Psychiatry 15:416-24. 2007..Antipsychotics are widely used to manage behavioral disorders in patients with dementia. Recently, serious concerns have been raised about the stroke and mortality risk of atypical antipsychotics when administered to patients with dementia... - Alcoholic beverage preference, 29-year mortality, and quality of life in men in old ageTimo E Strandberg
Department of Public Health Science and General Practice, University of Oulu, Finland
J Gerontol A Biol Sci Med Sci 62:213-8. 2007..We compared 29-year mortality and quality of life in old age by alcoholic beverage preference (beer, wine, or spirits) in a cohort of men whose socioeconomic status was similar in their adult life... - Psychotropic medication and stroke outcomeMinna M Raivio
Am J Psychiatry 162:1027; author reply 1027-8. 2005 - Cardiovascular risk in midlife and psychological well-being among older menTimo E Strandberg
Department of Public Health Science and General Practice, University of Oulu, Oulu, Finland
Arch Intern Med 166:2266-71. 2006..We investigated whether cardiovascular disease risk in midlife is related to psychological well-being in older men (aged 69-84 years old)... - Use of inappropriate medications and their prognostic significance among in-hospital and nursing home patients with and without dementia in FinlandMinna M Raivio
Department of General Internal Medicine and Geriatrics, University of Helsinki, Finland
Drugs Aging 23:333-43. 2006..This study examines the use of inappropriate drugs and their impact on mortality and use of health services among Finnish elderly nursing home and hospital patients. Patients with dementia were studied as a special subgroup... - Multicomponent geriatric intervention for elderly inpatients with delirium: a randomized, controlled trialKaisu H Pitkala
The Central Union for the Welfare of the Aged, Malmin Kauppatie 26, 00700 Helsinki, Finland
J Gerontol A Biol Sci Med Sci 61:176-81. 2006..Treatment is mainly based on common sense with wide variations in practice. We investigated whether intensified, multicomponent geriatric treatment could improve the prognosis of delirious patients... - Cholesterol and glucose metabolism and recurrent cardiovascular events among the elderly: a prospective studyTimo E Strandberg
Department of Public Health Science and General Practice, University of Oulu, Oulu, Finland
J Am Coll Cardiol 48:708-14. 2006.... - Social contacts and their relationship to loneliness among aged people - a population-based studyPirkko E Routasalo
Department of Nursing Science, University of Turku, Finland
Gerontology 52:181-7. 2006..This has implications for practice. Interventions aiming at relieving loneliness should be focused on enabling an individual to reflect her own expectations and inner feelings of loneliness... - Advance orders to limit therapy in 67 long-term care facilities in FinlandMarja Liisa Laakkonen
Helsinki City Hospital Koskela, P O Box 6410, FIN 00099 Helsinki, Finland
Resuscitation 61:333-9. 2004..To assess the documentation of a do-not-attempt-resuscitation (DNAR) or do-not-hospitalize (DNH) orders in the medical record and to determine factors related to these orders... - Multifactorial intervention to prevent recurrent cardiovascular events in patients 75 years or older: the Drugs and Evidence-Based Medicine in the Elderly (DEBATE) study: a randomized, controlled trialTimo E Strandberg
Department of Public Health Science and General Practice, University of Oulu, University Hospital, Oulu, Finland
Am Heart J 152:585-92. 2006..We aimed to examine whether better use of preventive methods and treatments of cardiovascular disease would reduce recurrent events in home-dwelling patients 75 years or older... - Physical and cognitive functioning and resuscitation preferences of aged patientsMarja-Lilsa Laakkonen
J Am Geriatr Soc 53:168-70. 2005 - Interest in healthy lifestyle and adherence to medications: Impact on mortality among elderly cardiovascular patients in the DEBATE StudyKaisu H Pitkala
University of Helsinki, Department of Primary Care and General Practice, Helsinki, Finland
Patient Educ Couns 67:44-9. 2007..We examined how a patient-centered consultation can help the physician to evaluate older patients' adherence to medical care and a healthy lifestyle. We hypothesised that an accurate estimate of adherence should be shown in their prognosis... - Older people's reasoning for resuscitation preferences and their role in the decision-making processMarja Liisa Laakkonen
Helsinki City Hospital Koskela, P O Box 6410, FIN 00099 Helsinki, Finland
Resuscitation 65:165-71. 2005..To investigate older patients' reasoning for their cardiopulmonary resuscitation (CPR) preferences and the related decision-making process (DMP)...