Seppo Santavirta

Summary

Affiliation: Helsinki University Central Hospital
Country: Finland

Publications

  1. ncbi request reprint Alternative materials to improve total hip replacement tribology
    Seppo Santavirta
    Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Helsinki, Finland
    Acta Orthop Scand 74:380-8. 2003
  2. ncbi request reprint [Materials for artificial joints]
    Seppo Santavirta
    Töölön sairaala, HUS
    Duodecim 120:2020-6. 2004
  3. ncbi request reprint Seppo Santavirta: the life and work of an orthopaedic surgeon and scientist. A tribute from his friends
    Yrjo T Konttinen
    University of Helsinki, Helsinki, Finland
    J Am Acad Orthop Surg 16:xii-xv. 2008
  4. ncbi request reprint Increased expression and processing of ADAM 12 (meltrin-alpha) in osteolysis associated with aseptic loosening of total hip replacement implants
    Guofeng Ma
    Department of Medicine Invärtes Medicin, Biomedicum, FIN 00029 Helsinki University Central Hospital, Helsinki, Finland
    J Rheumatol 32:1943-50. 2005
  5. ncbi request reprint Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K
    Jami Mandelin
    Institute of Biomedicine Anatomy, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
    J Rheumatol 32:713-20. 2005
  6. ncbi request reprint Bioabsorbable fixation devices in trauma and bone surgery: current clinical standing
    Eero Waris
    Peijas Hospital, Helsinki University Central Hospital, Finland and Biomedicum Helsinki, Institute of Biomedicine Anatomy, PO Box 63, FIN 00014 University of Helsinki, Finland
    Expert Rev Med Devices 1:229-40. 2004
  7. ncbi request reprint Operative and nonoperative treatments of medial collateral ligament rupture with early anterior cruciate ligament reconstruction: a prospective randomized study
    Jyrki Halinen
    Jorvi Hospital, Helsinki, Finland
    Am J Sports Med 34:1134-40. 2006
  8. pmc Fracture dislocations of the cervical spine: a review of 106 conservatively and operatively treated patients
    Mika P Koivikko
    Department of Radiology, Helsinki University Central Hospital, Toolo Trauma Center, Topeliuksenkatu 5, 00260, Helsinki, Finland
    Eur Spine J 13:610-6. 2004
  9. ncbi request reprint Immunohistochemical evaluation of inflammatory mediators in failing implants
    Yrjo T Konttinen
    Department of Medicine lnvartes Medicin, Helsinki University Central Hospital, Finland
    Int J Periodontics Restorative Dent 26:135-41. 2006
  10. ncbi request reprint Increased expression of a novel osteoclast-stimulating factor, ADAM8, in interface tissue around loosened hip prostheses
    Jami Mandelin
    Department of Anatomy, University of Helsinki, Helsinki, Finland
    J Rheumatol 30:2033-8. 2003

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Alternative materials to improve total hip replacement tribology
    Seppo Santavirta
    Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Helsinki, Finland
    Acta Orthop Scand 74:380-8. 2003
    ..Each of these bearing concepts will probably permit the use of larger head sizes, to reduce the risk of impingement and luxations...
  2. ncbi request reprint [Materials for artificial joints]
    Seppo Santavirta
    Töölön sairaala, HUS
    Duodecim 120:2020-6. 2004
  3. ncbi request reprint Seppo Santavirta: the life and work of an orthopaedic surgeon and scientist. A tribute from his friends
    Yrjo T Konttinen
    University of Helsinki, Helsinki, Finland
    J Am Acad Orthop Surg 16:xii-xv. 2008
  4. ncbi request reprint Increased expression and processing of ADAM 12 (meltrin-alpha) in osteolysis associated with aseptic loosening of total hip replacement implants
    Guofeng Ma
    Department of Medicine Invärtes Medicin, Biomedicum, FIN 00029 Helsinki University Central Hospital, Helsinki, Finland
    J Rheumatol 32:1943-50. 2005
    ..Macrophage-colony stimulating factor (M-CSF) and receptor activator of nuclear factor-kappaB ligand (RANKL) costimulation of human monocytes followed by FACS, immunofluorescence staining, Western blotting, and bone resorption assay...
  5. ncbi request reprint Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K
    Jami Mandelin
    Institute of Biomedicine Anatomy, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
    J Rheumatol 32:713-20. 2005
    ..We hypothesized that fibroblasts in the interface tissue may form a source for RANKL production...
  6. ncbi request reprint Bioabsorbable fixation devices in trauma and bone surgery: current clinical standing
    Eero Waris
    Peijas Hospital, Helsinki University Central Hospital, Finland and Biomedicum Helsinki, Institute of Biomedicine Anatomy, PO Box 63, FIN 00014 University of Helsinki, Finland
    Expert Rev Med Devices 1:229-40. 2004
    ..The risk of implant-associated stress shielding, peri-implant osteoporosis and infections is reduced. Implants do not interfere with clinical imaging. Current clinical use of bioabsorbable devices is reviewed...
  7. ncbi request reprint Operative and nonoperative treatments of medial collateral ligament rupture with early anterior cruciate ligament reconstruction: a prospective randomized study
    Jyrki Halinen
    Jorvi Hospital, Helsinki, Finland
    Am J Sports Med 34:1134-40. 2006
    ..The apparent consensus is that solitary medial collateral ligament rupture can be treated nonoperatively, but treatment of severe combined ruptures of the medial collateral ligament and anterior cruciate ligament remains controversial...
  8. pmc Fracture dislocations of the cervical spine: a review of 106 conservatively and operatively treated patients
    Mika P Koivikko
    Department of Radiology, Helsinki University Central Hospital, Toolo Trauma Center, Topeliuksenkatu 5, 00260, Helsinki, Finland
    Eur Spine J 13:610-6. 2004
    ..A significant number of the conservatively treated patients developed kyphotic deformity, and 29% needed later surgery because of chronic instability or unacceptable anatomical results...
  9. ncbi request reprint Immunohistochemical evaluation of inflammatory mediators in failing implants
    Yrjo T Konttinen
    Department of Medicine lnvartes Medicin, Helsinki University Central Hospital, Finland
    Int J Periodontics Restorative Dent 26:135-41. 2006
    ..These cytokines may contribute to peri-implant bone loss/loosening by stimulating formation and activity of osteoclasts and might be an amenable target for local therapies with cytokine modulators...
  10. ncbi request reprint Increased expression of a novel osteoclast-stimulating factor, ADAM8, in interface tissue around loosened hip prostheses
    Jami Mandelin
    Department of Anatomy, University of Helsinki, Helsinki, Finland
    J Rheumatol 30:2033-8. 2003
    ..Because loosening of hip replacement implants is characterized by foreign body giant cells and peri-implant osteoclasts, it was speculated that this molecule might be (over)expressed in the synovial membrane-like interface tissues...
  11. ncbi request reprint Current management: Management of rheumatic diseases in the era of biological anti-rheumatic drugs
    Yrjo T Konttinen
    Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Acta Orthop 76:614-9. 2005
  12. ncbi request reprint Self-reinforced bioabsorbable versus metallic fixation systems for metacarpal and phalangeal fractures: a biomechanical study
    Eero Waris
    Institute of Biomedicine Anatomy, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
    J Hand Surg Am 27:902-9. 2002
    ..The results show that by using ultra-high strength self-reinforced implants adequate fixation stability for hand fracture fixation can be achieved...
  13. ncbi request reprint Reciprocal age-related changes in GAP-43/B-50, substance P and calcitonin gene-related peptide (CGRP) expression in rat primary sensory neurones and their terminals in the dorsal horn of the spinal cord and subintima of the knee synovium
    Mika Hukkanen
    Institute of Biomedicine Anatomy, Biomedicum Helsinki, PO Box 63, Haartmaninkatu 8, FIN 00014 University of Helsinki, Helsinki, Finland
    Neurosci Res 42:251-60. 2002
    ....
  14. ncbi request reprint Compatibility of the totally replaced hip. Reduction of wear by amorphous diamond coating
    Seppo Santavirta
    Biomedical Technology Group, Department of Applied Physics, University of Kuopio, Finland
    Acta Orthop Scand Suppl 74:1-19. 2003
    ..The present work clearly shows that wear is one of the basic problems with totally replaced hips. Diamond coating of the bearing surfaces appears to be an attractive solution to improve longevity of the totally replaced hip...
  15. ncbi request reprint [Bioabsorbable devices in bone surgery]
    Eero Waris
    Mikkelin keskussairaala Porrassalmenkatu 35 7, 50100 Mikkeli
    Duodecim 120:673-81. 2004
  16. ncbi request reprint Biotribology
    Seppo Santavirta
    Acta Orthop 76:613. 2005
  17. ncbi request reprint [Tooth implant--a spare part becoming commonly used]
    Antti Pihakari
    Helsingin kaupungin terveyskeskus, Helsinki
    Duodecim 120:1474-82. 2004
  18. ncbi request reprint Arthroscopic operations in joint tuberculosis
    Alexei G Titov
    Sanct Petersburg State Scientific Research Institute of Phthisiopulmonology, Sanct Petersburg, Russia
    Knee 11:57-62. 2004
    ....
  19. ncbi request reprint Pseudosynovial fluid from loosened total hip prosthesis induces osteoclast formation
    Jami Mandelin
    Institute of Biomedicine Anatomy, Biomedicum Helsinki, University of Helsinki, Finland
    J Biomed Mater Res B Appl Biomater 74:582-8. 2005
    ..It is thus concluded that suppression of RANKL activity may be beneficial in terms of increasing the lifetime of total hip prostheses...
  20. ncbi request reprint Upregulation of matrix metalloproteinase (MMP)-1 and its activator MMP-3 of human osteoblast by uniaxial cyclic stimulation
    Kan Sasaki
    Department of Orthopaedic Surgery, Yamagata University School of Medicine, Yamagata, 990 9585, Japan
    J Biomed Mater Res B Appl Biomater 80:491-8. 2007
    ..The strain might also play a role in cleaning of demineralized bone surface during the reversal phase, before bone formation starts...
  21. ncbi request reprint Dense innervation in pseudocapsular tissue compared to aneural interface tissue in loose totally replaced hips
    Sirkku Niissalo
    Department of Oral Pathology and Oral Medicine, Institute of Dentistry, University of Helsinki, Finland
    J Rheumatol 29:796-803. 2002
    ..The function of many inflammatory cells is in part regulated by neuronal cells, which may lead to so-called neurogenic inflammation. Sensory nerves also mediate the pain sensation...