Seppo Santavirta

Summary

Affiliation: Helsinki University Central Hospital
Country: Finland

Publications

  1. ncbi Alternative materials to improve total hip replacement tribology
    Seppo Santavirta
    Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Helsinki, Finland
    Acta Orthop Scand 74:380-8. 2003
  2. ncbi [Materials for artificial joints]
    Seppo Santavirta
    , HUS
    Duodecim 120:2020-6. 2004
  3. ncbi Seppo Santavirta: the life and work of an orthopaedic surgeon and scientist. A tribute from his friends
    Yrjo T Konttinen
    University of Helsinki, Helsinki, Finland
    J Am Acad Orthop Surg 16:xii-xv. 2008
  4. ncbi Increased expression and processing of ADAM 12 (meltrin-alpha) in osteolysis associated with aseptic loosening of total hip replacement implants
    Guofeng Ma
    , Biomedicum, FIN-00029 Helsinki University Central Hospital, Helsinki, Finland
    J Rheumatol 32:1943-50. 2005
  5. ncbi Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K
    Jami Mandelin
    Institute of Biomedicine/Anatomy, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
    J Rheumatol 32:713-20. 2005
  6. ncbi Bioabsorbable fixation devices in trauma and bone surgery: current clinical standing
    Eero Waris
    Peijas Hospital, Helsinki University Central Hospital, Finland and Biomedicum Helsinki, Institute of Biomedicine Anatomy, PO Box 63, FIN 00014 University of Helsinki, Finland
    Expert Rev Med Devices 1:229-40. 2004
  7. ncbi Operative and nonoperative treatments of medial collateral ligament rupture with early anterior cruciate ligament reconstruction: a prospective randomized study
    Jyrki Halinen
    Jorvi Hospital, Helsinki, Finland
    Am J Sports Med 34:1134-40. 2006
  8. ncbi Fracture dislocations of the cervical spine: a review of 106 conservatively and operatively treated patients
    Mika P Koivikko
    Department of Radiology, Helsinki University Central Hospital, Toolo Trauma Center, Topeliuksenkatu 5, 00260, Helsinki, Finland
    Eur Spine J 13:610-6. 2004
  9. ncbi Current management: Management of rheumatic diseases in the era of biological anti-rheumatic drugs
    Yrjo T Konttinen
    Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Acta Orthop 76:614-9. 2005
  10. ncbi Immunohistochemical evaluation of inflammatory mediators in failing implants
    Yrjo T Konttinen
    Department of Medicine lnvartes Medicin, Helsinki University Central Hospital, Finland
    Int J Periodontics Restorative Dent 26:135-41. 2006

Collaborators

Detail Information

Publications21

  1. ncbi Alternative materials to improve total hip replacement tribology
    Seppo Santavirta
    Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Helsinki, Finland
    Acta Orthop Scand 74:380-8. 2003
    ..Each of these bearing concepts will probably permit the use of larger head sizes, to reduce the risk of impingement and luxations...
  2. ncbi [Materials for artificial joints]
    Seppo Santavirta
    , HUS
    Duodecim 120:2020-6. 2004
  3. ncbi Seppo Santavirta: the life and work of an orthopaedic surgeon and scientist. A tribute from his friends
    Yrjo T Konttinen
    University of Helsinki, Helsinki, Finland
    J Am Acad Orthop Surg 16:xii-xv. 2008
  4. ncbi Increased expression and processing of ADAM 12 (meltrin-alpha) in osteolysis associated with aseptic loosening of total hip replacement implants
    Guofeng Ma
    , Biomedicum, FIN-00029 Helsinki University Central Hospital, Helsinki, Finland
    J Rheumatol 32:1943-50. 2005
    ..It may play a role in formation of giant cells and osteoclasts around loosened total hip replacement implants...
  5. ncbi Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K
    Jami Mandelin
    Institute of Biomedicine/Anatomy, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
    J Rheumatol 32:713-20. 2005
    ..CONCLUSION: Interface tissue fibroblasts are able to produce RANKL, OPG, and cathepsin K and may contribute indirectly and directly to pathologic periprosthetic collagenolysis and bone destruction...
  6. ncbi Bioabsorbable fixation devices in trauma and bone surgery: current clinical standing
    Eero Waris
    Peijas Hospital, Helsinki University Central Hospital, Finland and Biomedicum Helsinki, Institute of Biomedicine Anatomy, PO Box 63, FIN 00014 University of Helsinki, Finland
    Expert Rev Med Devices 1:229-40. 2004
    ..The risk of implant-associated stress shielding, peri-implant osteoporosis and infections is reduced. Implants do not interfere with clinical imaging. Current clinical use of bioabsorbable devices is reviewed...
  7. ncbi Operative and nonoperative treatments of medial collateral ligament rupture with early anterior cruciate ligament reconstruction: a prospective randomized study
    Jyrki Halinen
    Jorvi Hospital, Helsinki, Finland
    Am J Sports Med 34:1134-40. 2006
    ..The apparent consensus is that solitary medial collateral ligament rupture can be treated nonoperatively, but treatment of severe combined ruptures of the medial collateral ligament and anterior cruciate ligament remains controversial...
  8. ncbi Fracture dislocations of the cervical spine: a review of 106 conservatively and operatively treated patients
    Mika P Koivikko
    Department of Radiology, Helsinki University Central Hospital, Toolo Trauma Center, Topeliuksenkatu 5, 00260, Helsinki, Finland
    Eur Spine J 13:610-6. 2004
    ..A significant number of the conservatively treated patients developed kyphotic deformity, and 29% needed later surgery because of chronic instability or unacceptable anatomical results...
  9. ncbi Current management: Management of rheumatic diseases in the era of biological anti-rheumatic drugs
    Yrjo T Konttinen
    Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland
    Acta Orthop 76:614-9. 2005
  10. ncbi Immunohistochemical evaluation of inflammatory mediators in failing implants
    Yrjo T Konttinen
    Department of Medicine lnvartes Medicin, Helsinki University Central Hospital, Finland
    Int J Periodontics Restorative Dent 26:135-41. 2006
    ..These cytokines may contribute to peri-implant bone loss/loosening by stimulating formation and activity of osteoclasts and might be an amenable target for local therapies with cytokine modulators...
  11. ncbi Increased expression of a novel osteoclast-stimulating factor, ADAM8, in interface tissue around loosened hip prostheses
    Jami Mandelin
    Department of Anatomy, University of Helsinki, Helsinki, Finland
    J Rheumatol 30:2033-8. 2003
    ..This is compatible with a role for ADAM8 in the formation of foreign body giant cells and osteoclasts...
  12. ncbi Self-reinforced bioabsorbable versus metallic fixation systems for metacarpal and phalangeal fractures: a biomechanical study
    Eero Waris
    Institute of Biomedicine/Anatomy, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
    J Hand Surg [Am] 27:902-9. 2002
    ..The results show that by using ultra-high strength self-reinforced implants adequate fixation stability for hand fracture fixation can be achieved...
  13. ncbi Reciprocal age-related changes in GAP-43/B-50, substance P and calcitonin gene-related peptide (CGRP) expression in rat primary sensory neurones and their terminals in the dorsal horn of the spinal cord and subintima of the knee synovium
    Mika Hukkanen
    Institute of Biomedicine Anatomy, Biomedicum Helsinki, PO Box 63, Haartmaninkatu 8, FIN 00014 University of Helsinki, Helsinki, Finland
    Neurosci Res 42:251-60. 2002
    ....
  14. ncbi Compatibility of the totally replaced hip. Reduction of wear by amorphous diamond coating
    Seppo Santavirta
    Biomedical Technology Group, Department of Applied Physics, University of Kuopio, Finland
    Acta Orthop Scand Suppl 74:1-19. 2003
    ..The present work clearly shows that wear is one of the basic problems with totally replaced hips. Diamond coating of the bearing surfaces appears to be an attractive solution to improve longevity of the totally replaced hip...
  15. ncbi Pseudosynovial fluid from loosened total hip prosthesis induces osteoclast formation
    Jami Mandelin
    Institute of Biomedicine/Anatomy, Biomedicum Helsinki, University of Helsinki, Finland
    J Biomed Mater Res B Appl Biomater 74:582-8. 2005
    ..It is thus concluded that suppression of RANKL activity may be beneficial in terms of increasing the lifetime of total hip prostheses...
  16. ncbi Upregulation of matrix metalloproteinase (MMP)-1 and its activator MMP-3 of human osteoblast by uniaxial cyclic stimulation
    Kan Sasaki
    Department of Orthopaedic Surgery, Yamagata University School of Medicine, Yamagata, 990 9585, Japan
    J Biomed Mater Res B Appl Biomater 80:491-8. 2007
    ..The strain might also play a role in cleaning of demineralized bone surface during the reversal phase, before bone formation starts...
  17. ncbi Arthroscopic operations in joint tuberculosis
    Alexei G Titov
    Sanct-Petersburg State Scientific Research Institute of Phthisiopulmonology, Sanct-Petersburg, Russia
    Knee 11:57-62. 2004
    ....
  18. ncbi [Bioabsorbable devices in bone surgery]
    Eero Waris
    Mikkelin keskussairaala Porrassalmenkatu 35-7, 50100 Mikkeli
    Duodecim 120:673-81. 2004
  19. ncbi Biotribology
    Seppo Santavirta
    Acta Orthop 76:613. 2005
  20. ncbi [Tooth implant--a spare part becoming commonly used]
    Antti Pihakari
    Helsingin kaupungin terveyskeskus, Helsinki
    Duodecim 120:1474-82. 2004
  21. ncbi Dense innervation in pseudocapsular tissue compared to aneural interface tissue in loose totally replaced hips
    Sirkku Niissalo
    Department of Oral Pathology and Oral Medicine, Institute of Dentistry, University of Helsinki, Finland
    J Rheumatol 29:796-803. 2002
    ..Failure in ubiquitin mediated proteolysis might support overgrowth of interface tissue and aseptic loosening...